Bayesian integrated testing strategy to assess skin sensitization potency: From theory to practice

Journal of Applied Toxicology

Volumn 33, Issue 11, 2013, Pages 1353-1364

  Jaworska, Joanna ^a   Dancik, Yuri ^a   Kern, Petra ^a   Gerberick, Frank ^a   Natsch, Andreas ^b  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b GIVAUDAN SCHWEIZ AG   (Switzerland)

Author keywords

Bayesian Network; Integrated testing strategy; LLNA potency class; Skin sensitization

Indexed keywords

CYSTEINE;

ARTICLE; BIOAVAILABILITY; CELL ACTIVATION; DENDRITIC CELL; IN VITRO STUDY; LOCAL LYMPH NODE ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SKIN SENSITIZATION; TOXICITY TESTING; ADVERSE DRUG REACTION; ANIMAL; ANIMAL TESTING ALTERNATIVE; BAYES THEOREM; BIOLOGICAL MODEL; CELL LINE; DERMATITIS, ALLERGIC CONTACT; FACTUAL DATABASE; IMMUNOLOGY; PREDICTIVE VALUE; PROCEDURES; STATISTICS AND NUMERICAL DATA;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BAYES THEOREM; CELL LINE; DATABASES, FACTUAL; DERMATITIS, ALLERGIC CONTACT; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; MODELS, BIOLOGICAL; PREDICTIVE VALUE OF TESTS; TOXICITY TESTS;

EID: 84884699708     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2869     Document Type: Article

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