A comparative evaluation of in vitro skin sensitisation tests: The human cell-line activation test (h-CLAT) versus the Local Lymph Node Assay (LLNA)

ATLA Alternatives to Laboratory Animals

Volumn 38, Issue 4, 2010, Pages 275-284

  Ashikaga, Takao ^a   Sakaguchi, Hitoshi ^b   Sono, Sakiko ^a   Kosaka, Nanae ^b   Ishikawa, Makie ^a   Nukada, Yuko ^b   Miyazawa, Masaaki ^b   Ito, Yuichi ^b   Nishiyama, Naohiro ^b   Itagaki, Hiroshi ^a  

^a SHISEIDO RESEARCH CENTER   (Japan)

^b KAO CORPORATION   (Japan)

Author keywords

Human cell line activation test; Skin sensitisation; THP 1

Indexed keywords

CD86 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LEUKOCYTE ANTIGEN; ORGANIC COMPOUND;

ARTICLE; CELL ACTIVATION; COMPARATIVE STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN CELL LINE ACTIVATION TEST; IN VITRO STUDY; LOCAL LYMPH NODE ASSAY; PRIORITY JOURNAL; SKIN SENSITIZATION; SKIN TEST; ANIMAL; ANIMAL TESTING ALTERNATIVE; CELL LINE; CELL SURVIVAL; CULTURE TECHNIQUE; DRUG EFFECT; IMMUNIZATION; IMMUNOLOGY; LYMPH NODE; METHODOLOGY; PREDICTION AND FORECASTING; SKIN; STANDARD;

ANIMAL TESTING ALTERNATIVES; ANIMALS; ANTIGENS, CD; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; HUMANS; IMMUNIZATION; LOCAL LYMPH NODE ASSAY; LYMPH NODES; ORGANIC CHEMICALS; PREDICTIVE VALUE OF TESTS; SKIN; SKIN TESTS;

EID: 78349276123     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119291003800403     Document Type: Article

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