A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation

Journal of Applied Toxicology

Volumn 33, Issue 11, 2013, Pages 1337-1352

  Natsch, Andreas ^a   Ryan, Cindy A ^b   Foertsch, Leslie ^b   Emter, Roger ^a   Jaworska, Joanna ^b   Gerberick, Frank ^b   Kern, Petra ^b  

^a GIVAUDAN SCHWEIZ AG   (Switzerland)

^b PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

CD86; Database; Dendritic cells; Direct peptide reactivity; DPRA; Integrated testing strategy; KeratinoSens ; Prevalidation; Skin sensitization; U937

Indexed keywords

2 PROPANOL; 4 HYDROXYBENZOIC ACID; 6 METHYLCOUMARIN; ACETOPHENONE; BENZALDEHYDE; BENZALDEHYDE DERIVATIVE; BENZALKONIUM CHLORIDE; BENZOCAINE; BENZOIC ACID; BUTANOL; CHLOROBENZENE; CLOFIBRATE; COUMARIN; GLYCEROL; HEXANE; LACTIC ACID; METHYL PARABEN; MYRISTIC ACID ISOPROPYL ESTER; NONANOIC ACID; OCTANOIC ACID; PHENYLACETIC ACID DERIVATIVE; PHTHALIC ACID DIETHYL ESTER; PROPYL PARABEN; PROPYLENE GLYCOL; SACCHARIN; STREPTOMYCIN SULFATE; SULFANILAMIDE; SULFANILIC ACID; TARTARIC ACID; VANILLIN; CD86 ANTIGEN; CD86 PROTEIN, HUMAN;

ACCURACY; ARTICLE; CORRELATION COEFFICIENT; DOSE RESPONSE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; HUMAN; HYDROPHOBICITY; KERATINOSENS ASSAY; LABORATORY TEST; MOLECULAR WEIGHT; PREDICTION; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REFERENCE DATABASE; SENSITIVITY AND SPECIFICITY; SKIN SENSITIZATION; ADVERSE DRUG REACTION; ANIMAL TESTING ALTERNATIVE; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; DERMATITIS, ALLERGIC CONTACT; DRUG EFFECTS; FACTUAL DATABASE; IMMUNOLOGY; PREDICTIVE VALUE; PROCEDURES; TOXICITY TESTING;

ANIMALIA;

ANIMAL TESTING ALTERNATIVES; ANTIGENS, CD86; CELL LINE; CELL SURVIVAL; DATABASES, FACTUAL; DERMATITIS, ALLERGIC CONTACT; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; HUMANS; MODELS, BIOLOGICAL; PREDICTIVE VALUE OF TESTS; TOXICITY TESTS;

EID: 84884702882     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2868     Document Type: Article

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