Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of Nrf2 by cancer chemotherapeutic agents

Cancer Research

Volumn 66, Issue 22, 2006, Pages 10983-10994

  Xiu, Jun Wang ^a   Hayes, John D ^a   Wolf, C Roland ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; AKRIC ENZYME; ALPHA TOCOPHEROL; ASCORBIC ACID; BUTHIONINE SULFOXIMINE; CARMUSTINE; CHLORAMBUCIL; CISPLATIN; ETOPOSIDE; GLUTATHIONE; LUCIFERASE; MELPHALAN; MITOXANTRONE; OXIDOREDUCTASE; TERT BUTYLHYDROQUINONE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG EXPOSURE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RECEPTOR GENE; RNA INTERFERENCE; TRANSGENE;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; BREAST NEOPLASMS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; LUCIFERASES; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; RESPONSE ELEMENTS; RNA, MESSENGER; TRANSFECTION; TRANSGENES;

EID: 33845297317     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-2298     Document Type: Article

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