Data integration of non-animal tests for the development of a test battery to predict the skin sensitizing potential and potency of chemicals

Toxicology in Vitro

Volumn 27, Issue 2, 2013, Pages 609-618

  Nukada, Yuko ^a   Miyazawa, Masaaki ^a   Kazutoshi, Saitou ^a   Sakaguchi, Hitoshi ^a   Nishiyama, Naohiro ^a  

^a KAO CORPORATION   (Japan)

Author keywords

DEREK; DPRA; H CLAT; In vitro test; Skin sensitization; Test battery

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 1 NAPHTHOL; 1,4 BENZOQUINONE; 3 AMINOPHENOL; ABIETIC ACID; BENZYL BROMIDE; BENZYLIDENEACETONE; CITRAL; COBALT CHLORIDE; DICHROMATE POTASSIUM; DIETHYL SULFATE; DIETHYLENETRIAMINE; DIPHENCYPRONE; DODECYL GALLATE; ETHYLENEDIAMINE; FORMALDEHYDE; GALLIC ACID PROPYL ESTER; GLUTARALDEHYDE; GLYOXAL; ISOEUGENOL; MALEIC ACID DIETHYL ESTER; MALEIC ANHYDRIDE; OXAZOLONE; PERILLALDEHYDE; PHENYLENEDIAMINE; PHTHALIC ANHYDRIDE; RESORCINOL; TETRACHLORSALAN; TOSYLCHLORAMIDE SODIUM;

ACCURACY; ARTICLE; COMPUTER MODEL; COMPUTER SYSTEM; CONTROLLED STUDY; DEREK; DIRECT PEPTIDE REACTIVITY ASSAY; HUMAN; HUMAN CELL; HUMAN CELL LINE ACTIVATION TEST; INTERMETHOD COMPARISON; LOCAL LYMPH NODE ASSAY; PREDICTION; PROCESS DEVELOPMENT; RELIABILITY; SENSITIVITY ANALYSIS; SKIN SENSITIZATION; TOXICITY TESTING;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; ANTIGENS, CD86; CELL LINE; CYSTEINE; DERMATITIS, ALLERGIC CONTACT; HAPTENS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LYSINE; MODELS, BIOLOGICAL; MONOCYTES; OLIGOPEPTIDES; PHARMACEUTICAL PREPARATIONS; PREDICTIVE VALUE OF TESTS; TOXICITY TESTS;

EID: 84875245378     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.11.006     Document Type: Article

References (26)

1. Ashikaga T., Sakaguchi H., Okamoto K., Mizuno M., Sato J., Yamada T., Yoshida M., Ota N., Hasegawa S., Kodama T., Okamoto Y., Kuwahara H., Kosaka N., Sono S., Ohno Y. Assessment of the human cell line activation test (h-CLAT) for skin sensitization; results of the first Japanese inter-laboratory study. AATEX 2008, 13:27-35.
2. Ashikaga T., Sakaguchi H., Sono S., Kosaka N., Ishikawa M., Nukada Y., Miyazawa M., Ito Y., Nishiyama N., Itagaki H. A comparative evaluation of in vitro skin sensitisation tests: the human cell-line activation test (h-CLAT) versus the local lymph node assay (LLNA). Altern. Lab. Anim. 2010, 38:275-284.
3. Bauch C., Kolle S.N., Fabian E., Pachel C., Ramirez T., Wiench B., Wruck C.J., van Ravenzwaay B., Landsiedel R. Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals. Toxicol. In Vitro 2011, 25:1162-1168.
4. Cooper J.A., Saracci R., Cole P. Describing the validity of carcinogen screening-tests. Br. J. Cancer 1979, 39:87-89.
5. Dimitrov S.D., Low L.K., Patlewicz G.Y., Kern P.S., Dimitrova G.D., Comber M.H., Phillips R.D., Niemela J., Bailey P.T., Mekenyan O.G. Skin sensitization: modeling based on skin metabolism simulation and formation of protein conjugates. Int. J. Toxicol. 2005, 24:189-204.
6. dos Santos G.G., Reinders J., Ouwehand K., Rustemeyer T., Scheper R.J., Gibbs S. Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound. Toxicol. Appl. Pharmacol. 2009, 236:372-382.
7. Emter R., Ellis G., Natsch A. Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro. Toxicol. Appl. Pharmacol. 2010, 245:281-290.
8. Gerberick G.F., Vassallo J.D., Bailey R.E., Chaney J.G., Morrall S.W., Lepoittevin J.P. Development of a peptide reactivity assay for screening contact allergens. Toxicol. Sci. 2004, 81:332-343.
9. Gerberick G.F., Ryan C.A., Kern P.S., Schlatter H., Dearman R.J., Kimber I., Patlewicz G.Y., Basketter D.A. Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods. Dermatitis 2005, 16:157-202.
10. Gerberick G.F., Vassallo J.D., Foertsch L.M., Price B.B., Chaney J.G., Lepoittevin J.P. Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach. Toxicol. Sci. 2007, 97:417-427.
11. Gerberick G.F., Ryan C.A., Dearman R.J., Kimber I. Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals. Methods 2007, 41:54-60.
12. Gerberick G.F., Troutman J.A., Foertsch L.M., Vassallo J.D., Quijano M., Dobson R.L., Goebel C., Lepoittevin J.P. Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system. Toxicol. Sci. 2009, 112:164-174.
13. Jaworska J., Harol A., Kern P.S., Gerberick G.F. Integrating non-animal test information into an adaptive testing strategy - skin sensitization proof of concept case. ALTEX 2011, 28:211-225.
14. Jowsey I.R., Basketter D.A., Westmoreland C., Kimber I. A future approach to measuring relative skin sensitising potency: a proposal. J. Appl. Toxicol. 2006, 26:341-350.
15. Kimber I., Basketter D.A., Gerberick G.F., Ryan C.A., Dearman R.J. Chemical allergy: translating biology into hazard characterization. Toxicol. Sci. 2011, 120:S238-S268.
16. McGarry H.F. The murine local lymph node assay: regulatory and potency considerations under REACH. Toxicology 2007, 238:71-89.
17. Megherbi R., Kiorpelidou E., Foster B., Rowe C., Naisbitt D.J., Goldring C.E., Park B.K. Role of protein haptenation in triggering maturation events in the dendritic cell surrogate cell line THP-1. Toxicol. Appl. Pharmacol. 2009, 238:120-132.
18. Miyazawa M., Ito Y., Yoshida Y., Sakaguchi H., Suzuki H. Phenotypic alterations and cytokine production in THP-1 cells in response to allergens. Toxicol. In Vitro 2007, 21:428-437.
19. Miyazawa M., Ito Y., Kosaka N., Nukada Y., Sakaguchi H., Suzuki H., Nishiyama N. Role of TNF-alpha and extracellular ATP in THP-1 cell activation following allergen exposure. J. Toxicol. Sci. 2008, 33:71-83.
20. Natsch A., Emter R., Ellis G. Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing. Toxicol. Sci. 2009, 107:106-121.
21. Nukada Y., Ashikaga T., Abo T., Sono S., Sakaguchi H., Itagaki H., Nishiyama N. Prediction of skin sensitization potential of chemicals by human cell line activation test (h-CLAT) and an attempt of classification of skin sensitization potency. The Toxicologist 2010, 127:301. (Abstract).
22. Nukada Y., Ashikaga T., Sakaguchi H., Sono S., Mugita N., Hirota M., Miyazawa M., Ito Y., Sasa H., Nishiyama N. Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT). Contact Dermatitis 2011, 65:343-353.
23. Sakaguchi H., Ashikaga T., Miyazawa M., Yoshida Y., Ito Y., Yoneyama K., Hirota M., Itagaki H., Toyoda H., Suzuki H. Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II. An inter-laboratory study of the h-CLAT. Toxicol. In Vitro 2006, 20:774-784.
24. Sakaguchi H., Ryan C., Ovigne J.M., Schroeder K.R., Ashikaga T. Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring trials. Toxicol. In Vitro 2010, 24:1810-1820.
25. Sanderson D.M., Earnshaw C.G. Computer prediction of possible toxic action from chemical structure; the DEREK system. Hum. Exp. Toxicol. 1991, 10:261-273.
26. Yoshida Y., Sakaguchi H., Ito Y., Okuda M., Suzuki H. Evaluation of the skin sensitization potential of chemicals using expression of co-stimulatory molecules, CD54 and CD86, on the naive THP-1 cell line. Toxicol. In Vitro 2003, 17:221-228.