Role of compartmentalization on HiF-1α degradation dynamics during changing oxygen conditions: A computational approach

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Bedessem, Baptiste ^a   Stéphanou, Angélique ^a  

^a LABORATOIRE TIMC IMAG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; VON HIPPEL LINDAU PROTEIN; ANTINEOPLASTIC AGENT; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, MOUSE; VHL PROTEIN, HUMAN; VHLH PROTEIN, MOUSE;

ARTICLE; CARCINOGENESIS; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CYTOPLASM; HYPOXIA; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MUTATION; REOXYGENATION; 3T3 CELL LINE; ACTIVE TRANSPORT; ANIMAL; CELL HYPOXIA; COMPUTER SIMULATION; CYTOSOL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOUSE; PROTEIN DEGRADATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; STATISTICAL MODEL; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL COMPARTMENTATION; CELL HYPOXIA; CELL LINE, TUMOR; CELL NUCLEUS; COMPUTER SIMULATION; CYTOSOL; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MODELS, STATISTICAL; MUTATION; NIH 3T3 CELLS; OXYGEN; PROTEIN STABILITY; PROTEOLYSIS; SIGNAL TRANSDUCTION; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84908510969     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110495     Document Type: Article

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