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Volumn 248, Issue 1, 2014, Pages 31-39

A mathematical model of HiF-1α-mediated response to hypoxia on the G1/S transition

Author keywords

Cancer; Cell cycle arrest; G1 S transition; HiF 1 ; Hypoxia; Quiescence

Indexed keywords

CANCER; CELL-CYCLE ARREST; G1/S TRANSITION; HYPOXIA; QUIESCENCE;

EID: 84893489829     PISSN: 00255564     EISSN: 18793134     Source Type: Journal    
DOI: 10.1016/j.mbs.2013.11.007     Document Type: Article
Times cited : (22)

References (54)
  • 1
    • 3042594418 scopus 로고    scopus 로고
    • A mathematical model of the effects of hypoxia on the cell-cycle of normal and cancer cells
    • Alarcon T., Byrne H.M., Maini P.K. A mathematical model of the effects of hypoxia on the cell-cycle of normal and cancer cells. J. Theor. Biol. 2004, 229:395.
    • (2004) J. Theor. Biol. , vol.229 , pp. 395
    • Alarcon, T.1    Byrne, H.M.2    Maini, P.K.3
  • 2
    • 78650810040 scopus 로고    scopus 로고
    • Quiescence: a mechanism for escaping the effects of drug on cell populations
    • Alarcon T., Jensen H.J. Quiescence: a mechanism for escaping the effects of drug on cell populations. J. R. Soc. Interface 2011, 8:99.
    • (2011) J. R. Soc. Interface , vol.8 , pp. 99
    • Alarcon, T.1    Jensen, H.J.2
  • 4
    • 84871261049 scopus 로고    scopus 로고
    • Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment
    • Bao B., Ali S., Ahmad A., Azmi A.S., Li Y., Banerjee S., Kong D., Sethi S., Aboukameel A., Padhye S.B., Sarkar F.H. Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment. PLoS One 2012, 7:e50165.
    • (2012) PLoS One , vol.7
    • Bao, B.1    Ali, S.2    Ahmad, A.3    Azmi, A.S.4    Li, Y.5    Banerjee, S.6    Kong, D.7    Sethi, S.8    Aboukameel, A.9    Padhye, S.B.10    Sarkar, F.H.11
  • 5
    • 34247627985 scopus 로고    scopus 로고
    • Cell size at s phase initiation: an emergent property of the G1/S network
    • Barberis M., Klipp E., Vanoni M., Alberghina L. Cell size at s phase initiation: an emergent property of the G1/S network. PLoS Comput. Biol. 2007, 3:e64.
    • (2007) PLoS Comput. Biol. , vol.3
    • Barberis, M.1    Klipp, E.2    Vanoni, M.3    Alberghina, L.4
  • 6
    • 10344240885 scopus 로고    scopus 로고
    • Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines
    • Box A.H., Demetrick D.J. Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines. Carcinogenesis 2004, 25:2325.
    • (2004) Carcinogenesis , vol.25 , pp. 2325
    • Box, A.H.1    Demetrick, D.J.2
  • 7
    • 22144493866 scopus 로고    scopus 로고
    • Negative and positive regulation of HiF-1: a complex network
    • Brdos J.I., Ashcroft M. Negative and positive regulation of HiF-1: a complex network. Biochim. Biophys. Acta 2005, 1755:107.
    • (2005) Biochim. Biophys. Acta , vol.1755 , pp. 107
    • Brdos, J.I.1    Ashcroft, M.2
  • 8
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown J.M., Wilson W.R. Exploiting tumour hypoxia in cancer treatment. Nat. Rev. Cancer 2004, 4:437.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 437
    • Brown, J.M.1    Wilson, W.R.2
  • 10
    • 20344384264 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor
    • Chen W.T., Huang C.J., Wu M.T., Yang S.F., Su Y.C., Chai C.Y. Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor. Jpn. J. Clin. Oncol. 2005, 35:207.
    • (2005) Jpn. J. Clin. Oncol. , vol.35 , pp. 207
    • Chen, W.T.1    Huang, C.J.2    Wu, M.T.3    Yang, S.F.4    Su, Y.C.5    Chai, C.Y.6
  • 12
    • 67449152160 scopus 로고    scopus 로고
    • Computational systems biology of the cell cycle
    • Csiksz-Nagy A. Computational systems biology of the cell cycle. Brief Bioinf. 2009, 10:424.
    • (2009) Brief Bioinf. , vol.10 , pp. 424
    • Csiksz-Nagy, A.1
  • 13
    • 84862822257 scopus 로고    scopus 로고
    • Up-regulation of hypoxia inducible factor-1 by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells
    • Dai Z.J., Gao J., Ma X.B., Yan K., Liu X.X., Kang H.F., Ji Z.Z., Guan H.T., Wang X.J. Up-regulation of hypoxia inducible factor-1 by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells. J. Exp. Clin. Cancer Res. 2012, 31:28.
    • (2012) J. Exp. Clin. Cancer Res. , vol.31 , pp. 28
    • Dai, Z.J.1    Gao, J.2    Ma, X.B.3    Yan, K.4    Liu, X.X.5    Kang, H.F.6    Ji, Z.Z.7    Guan, H.T.8    Wang, X.J.9
  • 14
    • 33745508920 scopus 로고    scopus 로고
    • Ubiquitylation of cyclin e requires the sequential function of SCF complexes containing distinct hCdc4 isoforms
    • van Drogen F., Sangfelt O., Malyukova A., Matskova L., Yeh E., Means A.R., Reed S.I. Ubiquitylation of cyclin e requires the sequential function of SCF complexes containing distinct hCdc4 isoforms. Mol. Cell 2006, 23:37.
    • (2006) Mol. Cell , vol.23 , pp. 37
    • van Drogen, F.1    Sangfelt, O.2    Malyukova, A.3    Matskova, L.4    Yeh, E.5    Means, A.R.6    Reed, S.I.7
  • 15
  • 16
    • 0442278330 scopus 로고    scopus 로고
    • Drosophila cyclin D/Cdk4 requires HiF-1 prolyl hydroxylase to drive cell growth
    • Frei C., Edgar B.A. Drosophila cyclin D/Cdk4 requires HiF-1 prolyl hydroxylase to drive cell growth. Dev. Cell 2004, 6:241.
    • (2004) Dev. Cell , vol.6 , pp. 241
    • Frei, C.1    Edgar, B.A.2
  • 18
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby R.A., Gillies R.J. Why do cancers have high aerobic glycolysis?. Nat. Rev. Cancer 2004, 4:891.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 891
    • Gatenby, R.A.1    Gillies, R.J.2
  • 19
    • 0042763564 scopus 로고    scopus 로고
    • HiF-1 in cell cycle regulation, apoptosis, and tumor progression
    • Goda N., Dozier S.J., Johnson R.S. HiF-1 in cell cycle regulation, apoptosis, and tumor progression. Antioxid. Redox Signal. 2003, 5:467.
    • (2003) Antioxid. Redox Signal. , vol.5 , pp. 467
    • Goda, N.1    Dozier, S.J.2    Johnson, R.S.3
  • 21
    • 0035145591 scopus 로고    scopus 로고
    • P21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest
    • Green S.L., Freiberg R.A., Giaccia A.J. p21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest. Mol. Cell Biol. 2001, 21:1196.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 1196
    • Green, S.L.1    Freiberg, R.A.2    Giaccia, A.J.3
  • 22
    • 34548292555 scopus 로고    scopus 로고
    • Hypoxic suppression of the cell cycle gene CDC25A in tumor cells
    • Hammer S., To K.K.W., Yoo Y.G., Koshiji M., Huang L.E. Hypoxic suppression of the cell cycle gene CDC25A in tumor cells. Cell Cycle 2007, 6:1919.
    • (2007) Cell Cycle , vol.6 , pp. 1919
    • Hammer, S.1    To, K.K.W.2    Yoo, Y.G.3    Koshiji, M.4    Huang, L.E.5
  • 23
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - a key regulatory factor in tumour growth
    • Harris A.L. Hypoxia - a key regulatory factor in tumour growth. Nat. Rev. Cancer 2002, 2:38.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38
    • Harris, A.L.1
  • 24
    • 79960702572 scopus 로고    scopus 로고
    • Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1-dependent manner in pancreatic cancer cells
    • Hashimoto O., Shimizu K., Semba S., Chiba S., Ku Y., Yokozaki H., Hori Y. Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1-dependent manner in pancreatic cancer cells. Pathobiology 2011, 78:181.
    • (2011) Pathobiology , vol.78 , pp. 181
    • Hashimoto, O.1    Shimizu, K.2    Semba, S.3    Chiba, S.4    Ku, Y.5    Yokozaki, H.6    Hori, Y.7
  • 25
    • 84893516697 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 induces chemoresistance phenotype in non-hodgkin lymphoma cell line via up-regulation of Bcl-(xL)
    • Hernandez-Luna M.A., Rocha-Zavaleta L., Vega M.I., Huerta-Yepez S. Hypoxia inducible factor-1 induces chemoresistance phenotype in non-hodgkin lymphoma cell line via up-regulation of Bcl-(xL). Leuk. Lymphoma 2012.
    • (2012) Leuk. Lymphoma
    • Hernandez-Luna, M.A.1    Rocha-Zavaleta, L.2    Vega, M.I.3    Huerta-Yepez, S.4
  • 26
    • 84857198083 scopus 로고    scopus 로고
    • Drosophila cyclin D/Cdk4 regulates mitochondrial biogenesis and aging and sensitizes animals to hypoxic stress
    • Icreverzi A., de la Cruz A.F., Voorhies W.A.V., Edgar B.A. Drosophila cyclin D/Cdk4 regulates mitochondrial biogenesis and aging and sensitizes animals to hypoxic stress. Cell Cycle 2012, 11:554.
    • (2012) Cell Cycle , vol.11 , pp. 554
    • Icreverzi, A.1    de la Cruz, A.F.2    Voorhies, W.A.V.3    Edgar, B.A.4
  • 27
    • 0029859510 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
    • Jiang B.H., Semenza G.L., Bauer C., Marti H.H. Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am. J. Physiol. 1996, 271:C1172.
    • (1996) Am. J. Physiol. , vol.271
    • Jiang, B.H.1    Semenza, G.L.2    Bauer, C.3    Marti, H.H.4
  • 28
    • 33947358207 scopus 로고    scopus 로고
    • Mutant p53 facilitates pro-angiogenic, hyperproliferative phenotype in response to chronic relative hypoxia
    • Kamat C.D., Green D.E., Warnke L., Thorpe J.E., Ceriello A., Ihnat M.A. Mutant p53 facilitates pro-angiogenic, hyperproliferative phenotype in response to chronic relative hypoxia. Cancer Lett. 2007, 249:209.
    • (2007) Cancer Lett. , vol.249 , pp. 209
    • Kamat, C.D.1    Green, D.E.2    Warnke, L.3    Thorpe, J.E.4    Ceriello, A.5    Ihnat, M.A.6
  • 29
    • 33751169387 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 (HiF-1)
    • Ke Q., Costa M. Hypoxia-inducible factor-1 (HiF-1). Mol. Pharmacol. 2006, 70:1469.
    • (2006) Mol. Pharmacol. , vol.70 , pp. 1469
    • Ke, Q.1    Costa, M.2
  • 30
    • 1842868935 scopus 로고    scopus 로고
    • Molecular responses to hypoxia in tumor cells
    • Kunz M., Ibrahim S.M. Molecular responses to hypoxia in tumor cells. Mol. Cancer 2003, 2:23.
    • (2003) Mol. Cancer , vol.2 , pp. 23
    • Kunz, M.1    Ibrahim, S.M.2
  • 31
    • 84864019874 scopus 로고    scopus 로고
    • On the importance of the submicrovascular network in a computational model of tumour growth
    • Lesart A.C., van der Sanden B., Hamard L., Esteve F., Stephanou A. On the importance of the submicrovascular network in a computational model of tumour growth. Microvasc. Res. 2012, 84:188.
    • (2012) Microvasc. Res. , vol.84 , pp. 188
    • Lesart, A.C.1    van der Sanden, B.2    Hamard, L.3    Esteve, F.4    Stephanou, A.5
  • 32
    • 0036203894 scopus 로고    scopus 로고
    • Phosphorylation of pRb is required for HGF-induced muscle cell proliferation and is p27kip1-dependent
    • Leshem Y., Halevy O. Phosphorylation of pRb is required for HGF-induced muscle cell proliferation and is p27kip1-dependent. J. Cell. Physiol. 2002, 191:173.
    • (2002) J. Cell. Physiol. , vol.191 , pp. 173
    • Leshem, Y.1    Halevy, O.2
  • 33
    • 84863499887 scopus 로고    scopus 로고
    • Microrna-mediated posttranscriptional mechanisms of gene expression in proliferating and quiescent cancer cells
    • Letonqueze O., Lee J., Vasudevan S. Microrna-mediated posttranscriptional mechanisms of gene expression in proliferating and quiescent cancer cells. RNA Biol. 2012, 9:871.
    • (2012) RNA Biol. , vol.9 , pp. 871
    • Letonqueze, O.1    Lee, J.2    Vasudevan, S.3
  • 34
    • 0035573882 scopus 로고    scopus 로고
    • The pvhl-hif-1 system. A key mediator of oxygen homeostasis
    • Maxwell P.H., Pugh C.W., Ratcliffe P.J. The pvhl-hif-1 system. A key mediator of oxygen homeostasis. Adv. Exp. Med. Biol. 2001, 502:365.
    • (2001) Adv. Exp. Med. Biol. , vol.502 , pp. 365
    • Maxwell, P.H.1    Pugh, C.W.2    Ratcliffe, P.J.3
  • 36
    • 4444349425 scopus 로고    scopus 로고
    • A model for restriction point control of the mammalian cell cycle
    • Novak B., Tyson J.J. A model for restriction point control of the mammalian cell cycle. J. Theor. Biol. 2004, 230:563.
    • (2004) J. Theor. Biol. , vol.230 , pp. 563
    • Novak, B.1    Tyson, J.J.2
  • 37
    • 33644622570 scopus 로고    scopus 로고
    • HiF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I., Cairns R.A., Fontana L., Lim A.L., Denko N.C. HiF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006, 3:187.
    • (2006) Cell Metab. , vol.3 , pp. 187
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 38
    • 10444280004 scopus 로고    scopus 로고
    • Cellular reaction to hypoxia: sensing and responding to an adverse environment
    • Papandreou I., Powell A., Lim A.L., Denko N. Cellular reaction to hypoxia: sensing and responding to an adverse environment. Mutat. Res. 2005, 569:87.
    • (2005) Mutat. Res. , vol.569 , pp. 87
    • Papandreou, I.1    Powell, A.2    Lim, A.L.3    Denko, N.4
  • 39
    • 0034789703 scopus 로고    scopus 로고
    • Lovastatin-induced e2f-1 modulation and its effect on prostate cancer cell death
    • Park C., Lee I., Kang W.K. Lovastatin-induced e2f-1 modulation and its effect on prostate cancer cell death. Carcinogenesis 2001, 22:1727.
    • (2001) Carcinogenesis , vol.22 , pp. 1727
    • Park, C.1    Lee, I.2    Kang, W.K.3
  • 40
    • 84861994004 scopus 로고    scopus 로고
    • Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model
    • Powathil G.G., Gordon K.E., Hill L.A., Chaplain M.A.J. Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model. J. Theor. Biol. 2012, 308:1.
    • (2012) J. Theor. Biol. , vol.308 , pp. 1
    • Powathil, G.G.1    Gordon, K.E.2    Hill, L.A.3    Chaplain, M.A.J.4
  • 41
    • 79953148385 scopus 로고    scopus 로고
    • Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling
    • Provenzano P.P., Keely P.J. Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. J. Cell Sci. 2011, 124:1195.
    • (2011) J. Cell Sci. , vol.124 , pp. 1195
    • Provenzano, P.P.1    Keely, P.J.2
  • 42
    • 40949142209 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factors in tumorigenesis
    • Rankin E.B., Giaccia A.J. The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ. 2008, 15:678.
    • (2008) Cell Death Differ. , vol.15 , pp. 678
    • Rankin, E.B.1    Giaccia, A.J.2
  • 44
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha (HiF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • Salceda S., Caro J. Hypoxia-inducible factor 1alpha (HiF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J. Biol. Chem. 1997, 272:22642.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22642
    • Salceda, S.1    Caro, J.2
  • 45
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HiF-1 for cancer therapy
    • Semenza G.L. Targeting HiF-1 for cancer therapy. Nat. Rev. Cancer 2003, 3:721.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 721
    • Semenza, G.L.1
  • 46
    • 35148828429 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 (HiF-1) pathway., Sci STKE 2007 cm8.
    • G.L. Semenza, Hypoxia-inducible factor 1 (HiF-1) pathway., Sci STKE 2007 (2007) cm8.
    • (2007)
    • Semenza, G.L.1
  • 47
    • 84859445000 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
    • Semenza G.L. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol. Sci. 2012, 33:207.
    • (2012) Trends Pharmacol. Sci. , vol.33 , pp. 207
    • Semenza, G.L.1
  • 48
    • 0037376168 scopus 로고    scopus 로고
    • Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells
    • Stacey D.W. Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells. Curr. Opin. Cell Biol. 2003, 15:158.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 158
    • Stacey, D.W.1
  • 49
    • 0035926571 scopus 로고    scopus 로고
    • Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions
    • Tyson J.J., Novak B. Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions. J. Theor. Biol. 2001, 210:249.
    • (2001) J. Theor. Biol. , vol.210 , pp. 249
    • Tyson, J.J.1    Novak, B.2
  • 50
    • 77950207236 scopus 로고    scopus 로고
    • Suppression of cyclin d1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of a549 cells
    • Wen W., Ding J., Sun W., Wu K., Ning B., Gong W., He G., Huang S., Ding X., Yin P., Chen L., Liu Q., Xie W., Wang H. Suppression of cyclin d1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of a549 cells. Cancer Res. 2010, 70:2010.
    • (2010) Cancer Res. , vol.70 , pp. 2010
    • Wen, W.1    Ding, J.2    Sun, W.3    Wu, K.4    Ning, B.5    Gong, W.6    He, G.7    Huang, S.8    Ding, X.9    Yin, P.10    Chen, L.11    Liu, Q.12    Xie, W.13    Wang, H.14
  • 51
    • 0027146274 scopus 로고
    • Growth factor regulation of cyclin d1 mrna expression through protein synthesis-dependent and -independent mechanisms
    • Winston J.T., Pledger W.J. Growth factor regulation of cyclin d1 mrna expression through protein synthesis-dependent and -independent mechanisms. Mol. Biol. Cell 1993, 4:1133.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1133
    • Winston, J.T.1    Pledger, W.J.2
  • 52
    • 34247167103 scopus 로고    scopus 로고
    • Variations in cyclin d1 levels through the cell cycle determine the proliferative fate of a cell
    • Yang K., Hitomi M., Stacey D.W. Variations in cyclin d1 levels through the cell cycle determine the proliferative fate of a cell. Cell Div. 2006, 1:32.
    • (2006) Cell Div. , vol.1 , pp. 32
    • Yang, K.1    Hitomi, M.2    Stacey, D.W.3
  • 54
    • 81755184035 scopus 로고    scopus 로고
    • Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct
    • Zhou W., Dosey T.L., Biechele T., Moon R.T., Horwitz M.S., Ruohola-Baker H. Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct. PLoS One 2011, 6:e27460.
    • (2011) PLoS One , vol.6
    • Zhou, W.1    Dosey, T.L.2    Biechele, T.3    Moon, R.T.4    Horwitz, M.S.5    Ruohola-Baker, H.6


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