A dynamic model of the hypoxia-inducible factor 1α(HIF-1α) network

Journal of Cell Science

Volumn 126, Issue 6, 2013, Pages 1454-1463

  Nguyen, Lan K ^a   Cavadas, Miguel A S ^a   Scholz, Carsten C ^a   Fitzpatrick, Susan F ^a   Bruning, Ulrike ^a   Cummins, Eoin P ^a   Tambuwala, Murtaza M ^a   Manresa, Mario C ^a   Kholodenko, Boris N ^a   Taylor, Cormac T ^a   Cheong, Alex ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

FIH; HIF; Hydroxylase; Hypoxia; Mathematical model

Indexed keywords

ASPARAGINYL HYDROXYLASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEASOME; UNCLASSIFIED DRUG;

ARTICLE; CELL HYPOXIA; COMPUTER MODEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE SILENCING; HUMAN; HUMAN CELL; HYDROXYLATION; IN VITRO STUDY; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; NETWORK LEARNING; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

FIH; HIF; HYDROXYLASE; HYPOXIA; MATHEMATICAL MODEL;

COMPUTATIONAL BIOLOGY; HEK293 CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; OXYGEN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; PROTEOLYSIS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 84877917354     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.119974     Document Type: Article

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