-
1
-
-
0032568448
-
Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha
-
An WG, Kanekal M, Simon MC, Maltepe E, Blagosklonny MV, Neckers LM (1998) Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha. Nature 392: 405-408
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
2
-
-
0029803552
-
An essential role for p300/CBP in the cellular response to hypoxia
-
Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, Bunn HF, Livingston DM (1996) An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci USA 93: 12969-12973
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12969-12973
-
-
Arany, Z.1
Huang, L.E.2
Eckner, R.3
Bhattacharya, S.4
Jiang, C.5
Goldberg, M.A.6
Bunn, H.F.7
Livingston, D.M.8
-
3
-
-
0030902253
-
Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells
-
Balajee AS, May A, Dianov GL, Friedberg EC, Bohr VA (1997) Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc Natl Acad Sci USA 94: 4306-4311
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4306-4311
-
-
Balajee, A.S.1
May, A.2
Dianov, G.L.3
Friedberg, E.C.4
Bohr, V.A.5
-
4
-
-
14244255484
-
The CSB protein actively wraps DNA
-
Beerens N, Hoeijmakers JH, Kanaar R, Vermeulen W, Wyman C (2005) The CSB protein actively wraps DNA. J Biol Chem 280: 4722-4729
-
(2005)
J Biol Chem
, vol.280
, pp. 4722-4729
-
-
Beerens, N.1
Hoeijmakers, J.H.2
Kanaar, R.3
Vermeulen, W.4
Wyman, C.5
-
5
-
-
0036809114
-
CSB is a component of RNA pol I transcription
-
Bradsher J, Auriol J, Proietti de Santis L, Iben S, Vonesch JL, Grummt I, Egly JM (2002) CSB is a component of RNA pol I transcription. Mol Cell 10: 819-829
-
(2002)
Mol Cell
, vol.10
, pp. 819-829
-
-
Bradsher, J.1
Auriol, J.2
Proietti de Santis, L.3
Iben, S.4
Vonesch, J.L.5
Grummt, I.6
Egly, J.M.7
-
6
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet P (2003) Angiogenesis in health and disease. Nat Med 9: 653-660
-
(2003)
Nat Med
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
7
-
-
0347479231
-
Oxidative stress is responsible for deficient survival and dendritogenesis in Purkinje neurons from ataxia-telangiectasia mutated mutant mice
-
Chen P, Peng C, Luff J, Spring K, Watters D, Bottle S, Furuya S, Lavin MF (2003) Oxidative stress is responsible for deficient survival and dendritogenesis in Purkinje neurons from ataxia-telangiectasia mutated mutant mice. J Neurosci 23: 11453-11460
-
(2003)
J Neurosci
, vol.23
, pp. 11453-11460
-
-
Chen, P.1
Peng, C.2
Luff, J.3
Spring, K.4
Watters, D.5
Bottle, S.6
Furuya, S.7
Lavin, M.F.8
-
8
-
-
0033806183
-
ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor
-
Citterio E, Van Den Boom V, Schnitzler G, Kanaar R, Bonte E, Kingston RE, Hoeijmakers JH, Vermeulen W (2000) ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor. Mol Cell Biol 20: 7643-7653
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7643-7653
-
-
Citterio, E.1
Van Den Boom, V.2
Schnitzler, G.3
Kanaar, R.4
Bonte, E.5
Kingston, R.E.6
Hoeijmakers, J.H.7
Vermeulen, W.8
-
9
-
-
0032945313
-
Alterations in the CSB gene in three Italian patients with the severe form of Cockayne syndrome (CS) but without clinical photosensitivity
-
Colella S, Nardo T, Mallery D, Borrone C, Ricci R, Ruffa G, Lehmann AR, Stefanini M (1999) Alterations in the CSB gene in three Italian patients with the severe form of Cockayne syndrome (CS) but without clinical photosensitivity. Hum Mol Genet 8: 935-941
-
(1999)
Hum Mol Genet
, vol.8
, pp. 935-941
-
-
Colella, S.1
Nardo, T.2
Mallery, D.3
Borrone, C.4
Ricci, R.5
Ruffa, G.6
Lehmann, A.R.7
Stefanini, M.8
-
10
-
-
33747194740
-
Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo
-
Fousteri M, Vermeulen W, van Zeeland AA, Mullenders LH (2006) Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo. Mol Cell 23: 471-482
-
(2006)
Mol Cell
, vol.23
, pp. 471-482
-
-
Fousteri, M.1
Vermeulen, W.2
van Zeeland, A.A.3
Mullenders, L.H.4
-
11
-
-
0028110809
-
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status
-
Graeber TG, Peterson JF, Tsai M, Monica K, Fornace Jr AJ, Giaccia AJ (1994) Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol Cell Biol 14: 6264-6277
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6264-6277
-
-
Graeber, T.G.1
Peterson, J.F.2
Tsai, M.3
Monica, K.4
Fornace Jr, A.J.5
Giaccia, A.J.6
-
12
-
-
0032741858
-
Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene
-
Graven KK, Yu Q, Pan D, Roncarati JS, Farber HW (1999) Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene. Biochim Biophys Acta 1447: 208-218
-
(1999)
Biochim Biophys Acta
, vol.1447
, pp. 208-218
-
-
Graven, K.K.1
Yu, Q.2
Pan, D.3
Roncarati, J.S.4
Farber, H.W.5
-
13
-
-
33747596652
-
Oxygen sensing by mitochondria at complex III: The paradox of increased reactive oxygen species during hypoxia
-
Guzy RD, Schumacker PT (2006) Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol 91: 807-819
-
(2006)
Exp Physiol
, vol.91
, pp. 807-819
-
-
Guzy, R.D.1
Schumacker, P.T.2
-
14
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100: 57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
15
-
-
0036359548
-
Hypoxia - a key regulatory factor in tumour growth
-
Harris AL (2002) Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38-47
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
16
-
-
0035868964
-
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
-
Ito A, Lai CH, Zhao X, Saito S, Hamilton MH, Appella E, Yao TP (2001) p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J 20: 1331-1340
-
(2001)
EMBO J
, vol.20
, pp. 1331-1340
-
-
Ito, A.1
Lai, C.H.2
Zhao, X.3
Saito, S.4
Hamilton, M.H.5
Appella, E.6
Yao, T.P.7
-
17
-
-
33745016466
-
The p53 family in nervous system development and disease
-
Jacobs WB, Kaplan DR, Miller FD (2006) The p53 family in nervous system development and disease. J Neurochem 97: 1571-1584
-
(2006)
J Neurochem
, vol.97
, pp. 1571-1584
-
-
Jacobs, W.B.1
Kaplan, D.R.2
Miller, F.D.3
-
18
-
-
31444444611
-
Initiation of DNA repair mediated by a stalled RNA polymerase IIO
-
Laine JP, Egly JM (2006) Initiation of DNA repair mediated by a stalled RNA polymerase IIO. EMBO J 25: 387-397
-
(2006)
EMBO J
, vol.25
, pp. 387-397
-
-
Laine, J.P.1
Egly, J.M.2
-
19
-
-
4644371659
-
Structural and functional adaptation to hypoxia in the rat brain
-
LaManna JC, Chavez JC, Pichiule P (2004) Structural and functional adaptation to hypoxia in the rat brain. J Exp Biol 207: 3163-3169
-
(2004)
J Exp Biol
, vol.207
, pp. 3163-3169
-
-
LaManna, J.C.1
Chavez, J.C.2
Pichiule, P.3
-
20
-
-
33846613301
-
Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice
-
Laposa RR, Huang EJ, Cleaver JE (2007) Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice. Proc Natl Acad Sci USA 104: 1389-1394
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1389-1394
-
-
Laposa, R.R.1
Huang, E.J.2
Cleaver, J.E.3
-
21
-
-
39749184830
-
Deletion of 50 sequences of the CSB gene provides insight into the pathophysiology of Cockayne syndrome
-
Laugel V, Dalloz C, Stary A, Cormier-Daire V, Desguerre I, Renouil M, Fourmaintraux A, Velez-Cruz R, Egly JM, Sarasin A, Dollfus H (2008) Deletion of 50 sequences of the CSB gene provides insight into the pathophysiology of Cockayne syndrome. Eur J Hum Genet 16: 320-327
-
(2008)
Eur J Hum Genet
, vol.16
, pp. 320-327
-
-
Laugel, V.1
Dalloz, C.2
Stary, A.3
Cormier-Daire, V.4
Desguerre, I.5
Renouil, M.6
Fourmaintraux, A.7
Velez-Cruz, R.8
Egly, J.M.9
Sarasin, A.10
Dollfus, H.11
-
22
-
-
4744348300
-
Hypoxia-induced nucleophosmin protects cell death through inhibition of p53
-
Li J, Zhang X, Sejas DP, Bagby GC, Pang Q (2004) Hypoxia-induced nucleophosmin protects cell death through inhibition of p53. J Biol Chem 279: 41275-41279
-
(2004)
J Biol Chem
, vol.279
, pp. 41275-41279
-
-
Li, J.1
Zhang, X.2
Sejas, D.P.3
Bagby, G.C.4
Pang, Q.5
-
23
-
-
0346101496
-
Cockayne syndrome group B cellular and biochemical functions
-
Licht CL, Stevnsner T, Bohr VA (2003) Cockayne syndrome group B cellular and biochemical functions. Am J Hum Genet 73: 1217-1239
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1217-1239
-
-
Licht, C.L.1
Stevnsner, T.2
Bohr, V.A.3
-
24
-
-
0030973238
-
Binding and modulation of p53 by p300/CBP coactivators
-
Lill NL, Grossman SR, Ginsberg D, DeCaprio J, Livingston DM (1997) Binding and modulation of p53 by p300/CBP coactivators. Nature 387: 823-827
-
(1997)
Nature
, vol.387
, pp. 823-827
-
-
Lill, N.L.1
Grossman, S.R.2
Ginsberg, D.3
DeCaprio, J.4
Livingston, D.M.5
-
25
-
-
33745649668
-
The retinal vasculature and function of the neural retina in a rat model of retinopathy of prematurity
-
Liu K, Akula JD, Falk C, Hansen RM, Fulton AB (2006) The retinal vasculature and function of the neural retina in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci 47: 2639-2647
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 2639-2647
-
-
Liu, K.1
Akula, J.D.2
Falk, C.3
Hansen, R.M.4
Fulton, A.B.5
-
26
-
-
0027950513
-
DNA helicases: Enzymes with essential roles in all aspects of DNA metabolism
-
Matson SW, Bean DW, George JW (1994) DNA helicases: enzymes with essential roles in all aspects of DNA metabolism. Bioessays 16: 13-22
-
(1994)
Bioessays
, vol.16
, pp. 13-22
-
-
Matson, S.W.1
Bean, D.W.2
George, J.W.3
-
27
-
-
0026508774
-
Cockayne syndrome: Review of 140 cases
-
Nance MA, Berry SA (1992) Cockayne syndrome: review of 140 cases. Am J Med Genet 42: 68-84
-
(1992)
Am J Med Genet
, vol.42
, pp. 68-84
-
-
Nance, M.A.1
Berry, S.A.2
-
28
-
-
3042779529
-
p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment
-
Pan Y, Oprysko PR, Asham AM, Koch CJ, Simon MC (2004) p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. Oncogene 23: 4975-4983
-
(2004)
Oncogene
, vol.23
, pp. 4975-4983
-
-
Pan, Y.1
Oprysko, P.R.2
Asham, A.M.3
Koch, C.J.4
Simon, M.C.5
-
29
-
-
33646589650
-
Cockayne syndrome B protein regulates the transcriptional program after UV irradiation
-
Proietti-De-Santis L, Drane P, Egly JM (2006) Cockayne syndrome B protein regulates the transcriptional program after UV irradiation. EMBO J 25: 1915-1923
-
(2006)
EMBO J
, vol.25
, pp. 1915-1923
-
-
Proietti-De-Santis, L.1
Drane, P.2
Egly, J.M.3
-
30
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
Pugh CW, Ratcliffe PJ (2003) Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 9: 677-684
-
(2003)
Nat Med
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
31
-
-
35348954836
-
UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway
-
Rapisarda A, Melillo G (2007) UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway. Oncogene 26: 6875-6884
-
(2007)
Oncogene
, vol.26
, pp. 6875-6884
-
-
Rapisarda, A.1
Melillo, G.2
-
32
-
-
33846054328
-
New insights for understanding the transcription-coupled repair pathway
-
Sarasin A, Stary A (2007) New insights for understanding the transcription-coupled repair pathway. DNA Repair 6: 265-269
-
(2007)
DNA Repair
, vol.6
, pp. 265-269
-
-
Sarasin, A.1
Stary, A.2
-
33
-
-
26944448202
-
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: Insights for transcription-coupled repair and Cockayne syndrome
-
Sarker AH, Tsutakawa SE, Kostek S, Ng C, Shin DS, Peris M, Campeau E, Tainer JA, Nogales E, Cooper PK (2005) Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne syndrome. Mol Cell 20: 187-198
-
(2005)
Mol Cell
, vol.20
, pp. 187-198
-
-
Sarker, A.H.1
Tsutakawa, S.E.2
Kostek, S.3
Ng, C.4
Shin, D.S.5
Peris, M.6
Campeau, E.7
Tainer, J.A.8
Nogales, E.9
Cooper, P.K.10
-
34
-
-
2642574174
-
p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1)
-
Schmid T, Zhou J, Kohl R, Brune B (2004) p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1). Biochem J 380: 289-295
-
(2004)
Biochem J
, vol.380
, pp. 289-295
-
-
Schmid, T.1
Zhou, J.2
Kohl, R.3
Brune, B.4
-
35
-
-
0030822591
-
Cockayne syndrome group B protein enhances elongation by RNA polymerase II
-
Selby CP, Sancar A (1997) Cockayne syndrome group B protein enhances elongation by RNA polymerase II. Proc Natl Acad Sci USA 94: 11205-11209
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11205-11209
-
-
Selby, C.P.1
Sancar, A.2
-
36
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL (2003) Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
37
-
-
33645786505
-
Development of novel therapeutic strategies that target HIF-1
-
Semenza GL (2006) Development of novel therapeutic strategies that target HIF-1. Expert Opin Ther Targets 10: 267-280
-
(2006)
Expert Opin Ther Targets
, vol.10
, pp. 267-280
-
-
Semenza, G.L.1
-
38
-
-
0030667078
-
Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes
-
Tantin D, Kansal A, Carey M (1997) Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes. Mol Cell Biol 17: 6803-6814
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6803-6814
-
-
Tantin, D.1
Kansal, A.2
Carey, M.3
-
39
-
-
0026465665
-
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
-
Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH (1992) ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 71: 939-953
-
(1992)
Cell
, vol.71
, pp. 939-953
-
-
Troelstra, C.1
van Gool, A.2
de Wit, J.3
Vermeulen, W.4
Bootsma, D.5
Hoeijmakers, J.H.6
-
40
-
-
0030826732
-
The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex
-
van Gool AJ, Citterio E, Rademakers S, van Os R, Vermeulen W, Constantinou A, Egly JM, Bootsma D, Hoeijmakers JH (1997) The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex. EMBO J 16: 5955-5965
-
(1997)
EMBO J
, vol.16
, pp. 5955-5965
-
-
van Gool, A.J.1
Citterio, E.2
Rademakers, S.3
van Os, R.4
Vermeulen, W.5
Constantinou, A.6
Egly, J.M.7
Bootsma, D.8
Hoeijmakers, J.H.9
-
41
-
-
34547743163
-
Activation of RNA polymerase I transcription by Cockayne syndrome group B protein and histone methyltransferase G9a
-
Yuan X, Feng W, Imhof A, Grummt I, Zhou Y (2007) Activation of RNA polymerase I transcription by Cockayne syndrome group B protein and histone methyltransferase G9a. Mol Cell 27: 585-595
-
(2007)
Mol Cell
, vol.27
, pp. 585-595
-
-
Yuan, X.1
Feng, W.2
Imhof, A.3
Grummt, I.4
Zhou, Y.5
-
42
-
-
0033593199
-
Role for p300 in stabilization of p53 in the response to DNA damage
-
Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Shioya H, Utsugisawa Y, Yokoyama K, Weichselbaum R, Shi Y, Kufe D (1999) Role for p300 in stabilization of p53 in the response to DNA damage. J Biol Chem 274: 1883-1886
-
(1999)
J Biol Chem
, vol.274
, pp. 1883-1886
-
-
Yuan, Z.M.1
Huang, Y.2
Ishiko, T.3
Nakada, S.4
Utsugisawa, T.5
Shioya, H.6
Utsugisawa, Y.7
Yokoyama, K.8
Weichselbaum, R.9
Shi, Y.10
Kufe, D.11
|