Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes

Molecular Metabolism

Volumn 3, Issue 8, 2014, Pages 781-793

  Henstridge, Darren C ^a   Whitham, Martin ^a   Febbraio, Mark A ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Chemical chaperones; Hsp72; Inflammation; Insulin resistance; Mitochondria; Obesity; Oxidative capacity; Skeletal muscle; Type 2 diabetes

Indexed keywords

4 PHENYLBUTYRIC ACID; CHAPERONE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; O (2 HYDROXY 3 PIPERIDINOPROPYL)NICOTINIC AMIDOXIME; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; TAUROURSODEOXYCHOLIC ACID;

AGING; CELL FUNCTION; CELL STRUCTURE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; GENE DELETION; GENE OVEREXPRESSION; GLUCOSE HOMEOSTASIS; HSP27 GENE; HUMAN; HYPERTHERMIC THERAPY; INFLAMMATION; INSULIN RESISTANCE; LIPID DIET; METABOLIC DISORDER; MITOCHONDRION; MITOPHAGY; MOLECULAR INTERACTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; REVIEW; VASCULAR DISEASE;

EID: 84908204729     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2014.08.003     Document Type: Review

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