-
1
-
-
33646178955
-
Reciprocal relationships between insulin resistance and endothelial dysfunction: Molecular and pathophysiological mechanisms
-
Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 2006;113:1888-1904
-
(2006)
Circulation
, vol.113
, pp. 1888-1904
-
-
Kim, J.A.1
Montagnani, M.2
Koh, K.K.3
Quon, M.J.4
-
2
-
-
0027261173
-
Insulin-mediated vasodilation: Impairment with increased blood pressure and body mass
-
Feldman RD, Bierbrier GS. Insulin-mediated vasodilation: impairment with increased blood pressure and body mass. Lancet 1993;342:707-709
-
(1993)
Lancet
, vol.342
, pp. 707-709
-
-
Feldman, R.D.1
Bierbrier, G.S.2
-
3
-
-
33745948085
-
Insulin resistance and endothelial dysfunction: The road map to cardiovascular diseases
-
Cersosimo E, DeFronzo RA. Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases. Diabetes Metab Res Rev 2006; 22:423-436
-
(2006)
Diabetes Metab Res Rev
, vol.22
, pp. 423-436
-
-
Cersosimo, E.1
Defronzo, R.A.2
-
4
-
-
83555172286
-
Insulin resistance induces a segmental difference in thoracic and abdominal aorta: Differential expression of AT1 and AT2 receptors
-
Karpe PA, Gupta J, Marthong RF, Ramarao P, Tikoo K. Insulin resistance induces a segmental difference in thoracic and abdominal aorta: differential expression of AT1 and AT2 receptors. J Hypertens 2012;30: 132-146
-
(2012)
J Hypertens
, vol.30
, pp. 132-146
-
-
Karpe, P.A.1
Gupta, J.2
Marthong, R.F.3
Ramarao, P.4
Tikoo, K.5
-
5
-
-
78650414197
-
Role of renin-angiotensin system blockades in reciprocal relationship between insulin resistance and endothelial dysfunction
-
Koh KK, Sakuma I, Quon MJ. Role of renin-angiotensin system blockades in reciprocal relationship between insulin resistance and endothelial dysfunction. Hypertension 2010;56:e169
-
(2010)
Hypertension
, vol.56
-
-
Koh, K.K.1
Sakuma, I.2
Quon, M.J.3
-
6
-
-
0842311015
-
Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance
-
Shinozaki K, Ayajiki K, Nishio Y, Sugaya T, Kashiwagi A, Okamura T. Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance. Hypertension 2004;43: 255-262
-
(2004)
Hypertension
, vol.43
, pp. 255-262
-
-
Shinozaki, K.1
Ayajiki, K.2
Nishio, Y.3
Sugaya, T.4
Kashiwagi, A.5
Okamura, T.6
-
7
-
-
20244388129
-
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
-
Kostenis E, Milligan G, Christopoulos A, et al. G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor. Circulation 2005;111:1806-1813
-
(2005)
Circulation
, vol.111
, pp. 1806-1813
-
-
Kostenis, E.1
Milligan, G.2
Christopoulos, A.3
-
8
-
-
77957374580
-
Advances in the renin angiotensin system focus on angiotensin-converting enzyme 2 and angiotensin-(1-7)
-
Ferrario CM, Ahmad S, Joyner JN, Varagic J. Advances in the renin angiotensin system focus on angiotensin-converting enzyme 2 and angiotensin-(1-7). Adv Pharmacol 2010;59:197-233
-
(2010)
Adv Pharmacol
, vol.59
, pp. 197-233
-
-
Ferrario, C.M.1
Ahmad, S.2
Joyner, J.N.3
Varagic, J.4
-
9
-
-
78149308747
-
The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells
-
Hayashi N, Yamamoto K, Ohishi M, et al. The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells. Hypertens Res 2010;33:1182-1185
-
(2010)
Hypertens Res
, vol.33
, pp. 1182-1185
-
-
Hayashi, N.1
Yamamoto, K.2
Ohishi, M.3
-
10
-
-
36448975192
-
Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells
-
Sampaio WO, Henrique de Castro C, Santos RAS, Schiffrin EL, Touyz RM. Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells. Hypertension 2007;50:1093-1098
-
(2007)
Hypertension
, vol.50
, pp. 1093-1098
-
-
Sampaio, W.O.1
De Castro, H.C.2
Santos, R.A.S.3
Schiffrin, E.L.4
Touyz, R.M.5
-
11
-
-
84879382289
-
Angiotensin (1-7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs
-
Tassone EJ, Sciacqua A, Andreozzi F, et al. Angiotensin (1-7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs. Cardiovasc Res 2013;99:129-136
-
(2013)
Cardiovasc Res
, vol.99
, pp. 129-136
-
-
Tassone, E.J.1
Sciacqua, A.2
Andreozzi, F.3
-
12
-
-
74949087578
-
Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases
-
Ferreira AJ, Santos RAS, Bradford CN, et al. Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases. Hypertension 2010;55:207-213
-
(2010)
Hypertension
, vol.55
, pp. 207-213
-
-
Ferreira, A.J.1
Santos, R.A.S.2
Bradford, C.N.3
-
13
-
-
84860643125
-
Impairment of cardiac function and remodeling induced by myocardial infarction in rats are attenuated by the nonpeptide angiotensin-(1-7) analog AVE 0991
-
Zeng WT, Chen WY, Leng XY, et al. Impairment of cardiac function and remodeling induced by myocardial infarction in rats are attenuated by the nonpeptide angiotensin-(1-7) analog AVE 0991. Cardiovasc Ther 2012;30: 152-161
-
(2012)
Cardiovasc Ther
, vol.30
, pp. 152-161
-
-
Zeng, W.T.1
Chen, W.Y.2
Leng, X.Y.3
-
14
-
-
36248993506
-
Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats
-
Benter IF, Yousif MHM, Dhaunsi GS, Kaur J, Chappell MC, Diz DI. Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats. Am J Nephrol 2008;28:25-33
-
(2008)
Am J Nephrol
, vol.28
, pp. 25-33
-
-
Benter, I.F.1
Yousif, M.H.M.2
Dhaunsi, G.S.3
Kaur, J.4
Chappell, M.C.5
Diz, D.I.6
-
15
-
-
20444423644
-
Angiotensin-(1-7) enhances LTP in the hippocampus through the G-protein-coupled receptor Mas
-
Hellner K, Walther T, Schubert M, Albrecht D. Angiotensin-(1-7) enhances LTP in the hippocampus through the G-protein-coupled receptor Mas. Mol Cell Neurosci 2005;29:427-435
-
(2005)
Mol Cell Neurosci
, vol.29
, pp. 427-435
-
-
Hellner, K.1
Walther, T.2
Schubert, M.3
Albrecht, D.4
-
16
-
-
34548851716
-
Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: More than regulation of blood pressure?
-
Chappell MC. Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: more than regulation of blood pressure? Hypertension 2007;50:596-599
-
(2007)
Hypertension
, vol.50
, pp. 596-599
-
-
Chappell, M.C.1
-
17
-
-
67650541842
-
Devil and angel in the renin-angiotensin system: ACEangiotensin II-AT1 receptor axis vs
-
Iwai M, Horiuchi M. Devil and angel in the renin-angiotensin system: ACEangiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-Mas receptor axis. Hypertens Res 2009;32:533-536
-
(2009)
ACE2-angiotensin-(1-7)-Mas Receptor Axis. Hypertens Res
, vol.32
, pp. 533-536
-
-
Iwai, M.1
Horiuchi, M.2
-
18
-
-
0032580971
-
Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis
-
Oemar BS, Tschudi MR, Godoy N, Brovkovich V, Malinski T, Lüscher TF. Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis. Circulation 1998;97:2494-2498
-
(1998)
Circulation
, vol.97
, pp. 2494-2498
-
-
Oemar, B.S.1
Tschudi, M.R.2
Godoy, N.3
Brovkovich, V.4
Malinski, T.5
Lüscher, T.F.6
-
19
-
-
0035943042
-
Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice
-
Kuhlencordt PJ, Gyurko R, Han F, et al. Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice. Circulation 2001;104:448-454
-
(2001)
Circulation
, vol.104
, pp. 448-454
-
-
Kuhlencordt, P.J.1
Gyurko, R.2
Han, F.3
-
20
-
-
0034004826
-
Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment
-
Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, Maeda N. Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. J Clin Invest 2000;105:451-458
-
(2000)
J Clin Invest
, vol.105
, pp. 451-458
-
-
Knowles, J.W.1
Reddick, R.L.2
Jennette, J.C.3
Shesely, E.G.4
Smithies, O.5
Maeda, N.6
-
21
-
-
84867743194
-
Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype
-
Sansbury BE, Cummins TD, Tang Y, et al. Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype. Circ Res 2012;111:1176-1189
-
(2012)
Circ Res
, vol.111
, pp. 1176-1189
-
-
Sansbury, B.E.1
Cummins, T.D.2
Tang, Y.3
-
22
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Nisoli E, Tonello C, Cardile A, et al. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 2005; 310:314-317
-
(2005)
Science
, vol.310
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
-
23
-
-
1842614317
-
Heat shock treatment protects against angiotensin II induced hypertension and inflammation in aorta
-
Chen Y, Ross BM, Currie RW. Heat shock treatment protects against angiotensin II induced hypertension and inflammation in aorta. Cell Stress Chaperones 2004;9: 99-107
-
(2004)
Cell Stress Chaperones
, vol.9
, pp. 99-107
-
-
Chen, Y.1
Ross, B.M.2
Currie, R.W.3
-
24
-
-
33745311153
-
Phosphatidylinositol 3-kinasedependent activation of akt, an essential signal for hyperthermia-induced heat-shock protein 72, is attenuated in streptozotocin-induced diabetic heart
-
Shinohara T, Takahashi N, Ooie T, et al. Phosphatidylinositol 3-kinasedependent activation of akt, an essential signal for hyperthermia-induced heat-shock protein 72, is attenuated in streptozotocin-induced diabetic heart. Diabetes 2006;55:1307-1315
-
(2006)
Diabetes
, vol.55
, pp. 1307-1315
-
-
Shinohara, T.1
Takahashi, N.2
Ooie, T.3
-
25
-
-
63849147182
-
Heat shock proteins in diabetes and wound healing
-
Atalay M, Oksala N, Lappalainen J, Laaksonen DE, Sen CK, Roy S. Heat shock proteins in diabetes and wound healing. Curr Protein Pept Sci 2009; 10:85-95
-
(2009)
Curr Protein Pept Sci
, vol.10
, pp. 85-95
-
-
Atalay, M.1
Oksala, N.2
Lappalainen, J.3
Laaksonen, D.E.4
Sen, C.K.5
Roy, S.6
-
26
-
-
0042822096
-
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: Evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism
-
Bruce CR, Carey AL, Hawley JA, Febbraio MA. Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism. Diabetes 2003;52:2338-2345
-
(2003)
Diabetes
, vol.52
, pp. 2338-2345
-
-
Bruce, C.R.1
Carey, A.L.2
Hawley, J.A.3
Febbraio, M.A.4
-
27
-
-
73649109601
-
A novel combination of mild electrical stimulation and hyperthermia: General concepts and applications
-
Kai H, Suico MA, Morino S, et al. A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications. Int J Hyperthermia 2009;25:655-660
-
(2009)
Int J Hyperthermia
, vol.25
, pp. 655-660
-
-
Kai, H.1
Suico, M.A.2
Morino, S.3
-
29
-
-
62749130586
-
Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet
-
Gupte AA, Bomhoff GL, Swerdlow RH, Geiger PC. Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet. Diabetes 2009;58:567-578
-
(2009)
Diabetes
, vol.58
, pp. 567-578
-
-
Gupte, A.A.1
Bomhoff, G.L.2
Swerdlow, R.H.3
Geiger, P.C.4
-
30
-
-
84878107240
-
Epigenetics: The link between nature and nurture
-
Tammen SA, Friso S, Choi S-W. Epigenetics: the link between nature and nurture. Mol Aspects Med 2013;34:753-764
-
(2013)
Mol Aspects Med
, vol.34
, pp. 753-764
-
-
Tammen, S.A.1
Friso, S.2
Choi, S.-W.3
-
31
-
-
4544225646
-
The cell-specific expression of endothelial nitric-oxide synthase: A role for DNA methylation
-
Chan Y, Fish JE, D'Abreo C, et al. The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation. J Biol Chem 2004; 279:35087-35100
-
(2004)
J Biol Chem
, vol.279
, pp. 35087-35100
-
-
Chan, Y.1
Fish, J.E.2
D'abreo, C.3
-
32
-
-
83255186739
-
SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities
-
Peng L, Yuan Z, Ling H, et al. SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Mol Cell Biol 2011;31: 4720-4734
-
(2011)
Mol Cell Biol
, vol.31
, pp. 4720-4734
-
-
Peng, L.1
Yuan, Z.2
Ling, H.3
-
33
-
-
84856269852
-
MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor a gene
-
Wang Y-S, Chou W-W, Chen K-C, Cheng H-Y, Lin R-T, Juo S-HH. MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor a gene. PLoS One 2012;7:e30635
-
(2012)
PLoS One
, vol.7
-
-
Wang, Y.-S.1
Chou, W.-W.2
Chen, K.-C.3
Cheng, H.-Y.4
Lin, R.-T.5
Juo, S.-H.H.6
-
34
-
-
4143151681
-
Heat shock treatment suppresses angiotensin II-induced activation of NF-kappaB pathway and heart inflammation: A role for IKK depletion by heat shock?
-
Chen Y, Arrigo AP, Currie RW. Heat shock treatment suppresses angiotensin II-induced activation of NF-kappaB pathway and heart inflammation: a role for IKK depletion by heat shock? Am J Physiol Heart Circ Physiol 2004;287:H1104-H1114
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Chen, Y.1
Arrigo, A.P.2
Currie, R.W.3
-
35
-
-
77956178364
-
Heat shock augments angiotensin II-induced vascular contraction through increased production of reactive oxygen species
-
Kim JI, Jung SW, Yang E, Park KM, Eto M, Kim IK. Heat shock augments angiotensin II-induced vascular contraction through increased production of reactive oxygen species. Biochem Biophys Res Commun 2010;399: 452-457
-
(2010)
Biochem Biophys Res Commun
, vol.399
, pp. 452-457
-
-
Kim, J.I.1
Jung, S.W.2
Yang, E.3
Park, K.M.4
Eto, M.5
Kim, I.K.6
-
36
-
-
60749101582
-
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
-
Westerheide SD, Anckar J, Stevens SM Jr, Sistonen L, Morimoto RI. Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 2009;323:1063-1066
-
(2009)
Science
, vol.323
, pp. 1063-1066
-
-
Westerheide, S.D.1
Anckar, J.2
Stevens Jr., S.M.3
Sistonen, L.4
Morimoto, R.I.5
-
37
-
-
0036227062
-
Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance
-
Kurucz I, Morva A, Vaag A, et al. Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance. Diabetes 2002;51:1102-1109
-
(2002)
Diabetes
, vol.51
, pp. 1102-1109
-
-
Kurucz, I.1
Morva, A.2
Vaag, A.3
-
38
-
-
84878613877
-
Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles
-
Sindler AL, Reyes R, Chen B, et al. Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles. J Appl Physiol (1985) 2013;114:681-693
-
(2013)
J Appl Physiol (1985)
, vol.114
, pp. 681-693
-
-
Sindler, A.L.1
Reyes, R.2
Chen, B.3
-
39
-
-
84875727264
-
SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: Implications for vascular aging
-
Zarzuelo MJ, López-Sepúlveda R, Sánchez M, et al. SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging. Biochem Pharmacol 2013;85: 1288-1296
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 1288-1296
-
-
Zarzuelo, M.J.1
López-Sepúlveda, R.2
Sánchez, M.3
-
40
-
-
33847018997
-
Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways
-
Sampaio WO, Souza dos Santos RA, Faria-Silva R, da Mata Machado LT, Schiffrin EL, Touyz RM. Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways. Hypertension 2007;49:185-192
-
(2007)
Hypertension
, vol.49
, pp. 185-192
-
-
Sampaio, W.O.1
Souza Dos Santos, R.A.2
Faria-Silva, R.3
Da Mata Machado, L.T.4
Schiffrin, E.L.5
Touyz, R.M.6
-
41
-
-
42649115768
-
Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)- Mas axis
-
Santos RA, Ferreira AJ, Simões E Silva AC. Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis. Exp Physiol 2008;93:519-527
-
(2008)
Exp Physiol
, vol.93
, pp. 519-527
-
-
Santos, R.A.1
Ferreira, A.J.2
Simões Silva, E.A.C.3
-
42
-
-
0034784780
-
Heat shock proteins and cardiovascular pathophysiology
-
Snoeckx LHEH, Cornelussen RN, Van Nieuwenhoven FA, Reneman RS, Van Der Vusse GJ. Heat shock proteins and cardiovascular pathophysiology. Physiol Rev 2001;81:1461-1497
-
(2001)
Physiol Rev
, vol.81
, pp. 1461-1497
-
-
Snoeckx, L.H.E.H.1
Cornelussen, R.N.2
Van Nieuwenhoven, F.A.3
Reneman, R.S.4
Van Der Vusse, G.J.5
-
43
-
-
69149087790
-
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density
-
Barrès R, Osler ME, Yan J, et al. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab 2009;10:189-198
-
(2009)
Cell Metab
, vol.10
, pp. 189-198
-
-
Barrès, R.1
Osler, M.E.2
Yan, J.3
-
44
-
-
23944472129
-
Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats
-
Igase M, Strawn WB, Gallagher PE, Geary RL, Ferrario CM. Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2005; 289:H1013-H1019
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Igase, M.1
Strawn, W.B.2
Gallagher, P.E.3
Geary, R.L.4
Ferrario, C.M.5
-
45
-
-
84876588807
-
Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2
-
Varagic J, Ahmad S, VonCannon JL, et al. Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats. Am J Hypertens 2013;26:583-590
-
(2013)
Lewis Rats. Am J Hypertens
, vol.26
, pp. 583-590
-
-
Varagic, J.1
Ahmad, S.2
Voncannon, J.L.3
-
46
-
-
60849095515
-
Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in rats
-
Giani JF, Mayer MA, Muñoz MC, et al. Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in rats. Am J Physiol Endocrinol Metab 2009;296:E262-E271
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Giani, J.F.1
Mayer, M.A.2
Muñoz, M.C.3
-
47
-
-
55949126600
-
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function
-
Rentzsch B, Todiras M, Iliescu R, et al. Transgenic angiotensin- converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension 2008;52:967-973
-
(2008)
Hypertension
, vol.52
, pp. 967-973
-
-
Rentzsch, B.1
Todiras, M.2
Iliescu, R.3
-
48
-
-
0037478671
-
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas
-
Santos RAS, Simoes e Silva AC, Maric C, et al. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci USA 2003;100:8258-8263
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8258-8263
-
-
Santos, R.A.S.1
Simoes, E.S.A.C.2
Maric, C.3
-
49
-
-
84875442204
-
Angiotensin 1-7 as means to prevent the metabolic syndrome: Lessons from the fructose-fed rat model
-
Marcus Y, Shefer G, Sasson K, et al. Angiotensin 1-7 as means to prevent the metabolic syndrome: lessons from the fructose-fed rat model. Diabetes 2013;62:1121-1130
-
(2013)
Diabetes
, vol.62
, pp. 1121-1130
-
-
Marcus, Y.1
Shefer, G.2
Sasson, K.3
-
50
-
-
84880927634
-
Oral formulation of angiotensin-(1-7) improves lipid metabolism and prevents high-fat diet-induced hepatic steatosis and inflammation in mice
-
Feltenberger JD, Andrade JM, Paraíso A, et al. Oral formulation of angiotensin-(1-7) improves lipid metabolism and prevents high-fat diet-induced hepatic steatosis and inflammation in mice. Hypertension 2013;62:324-330
-
(2013)
Hypertension
, vol.62
, pp. 324-330
-
-
Feltenberger, J.D.1
Andrade, J.M.2
Paraíso, A.3
-
51
-
-
84879043544
-
Oral angiotensin-(1-7) prevented obesity and hepatic inflammation by inhibition of resistin/Tlr4/ mapk/NF-kB in rats fed with high-fat diet
-
Santos SH, Andrade JM, Fernandes LR, et al. Oral angiotensin-(1-7) prevented obesity and hepatic inflammation by inhibition of resistin/Tlr4/ mapk/NF-kB in rats fed with high-fat diet. Peptides 2013;46:47-52
-
(2013)
Peptides
, vol.46
, pp. 47-52
-
-
Santos, S.H.1
Andrade, J.M.2
Fernandes, L.R.3
-
52
-
-
84875214685
-
Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity
-
Beyer AM, Guo D-F, Rahmouni K. Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity. J Hypertens 2013;31:730-738
-
(2013)
J Hypertens
, vol.31
, pp. 730-738
-
-
Beyer, A.M.1
Guo, D.-F.2
Rahmouni, K.3
-
53
-
-
33644860787
-
Angiotensin-(1-7) prevents development of severe hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME
-
Benter IF, Yousif MHM, Anim JT, Cojocel C, Diz DI. Angiotensin-(1-7) prevents development of severe hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME. Am J Physiol Heart Circ Physiol 2006;290:H684-H691
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Benter, I.F.1
Yousif, M.H.M.2
Anim, J.T.3
Cojocel, C.4
Diz, D.I.5
-
54
-
-
77955864813
-
AVE 0991-angiotensin-(1-7) receptor agonist, inhibits atherogenesis in apoE-knockout mice
-
Toton-Zuranska J, Gajda M, Pyka-Fosciak G, et al. AVE 0991-angiotensin-(1-7) receptor agonist, inhibits atherogenesis in apoE-knockout mice. J Physiol Pharmacol 2010;61:181-183
-
(2010)
J Physiol Pharmacol
, vol.61
, pp. 181-183
-
-
Toton-Zuranska, J.1
Gajda, M.2
Pyka-Fosciak, G.3
-
55
-
-
84873716865
-
The nonpeptide ANG-(1-7) mimic AVE 0991 attenuates cardiac remodeling and improves baroreflex sensitivity in renovascular hypertensive rats
-
Cunha TMB, Lima WG, Silva ME, Souza Santos RA, Campagnole-Santos MJ, Alzamora AC. The nonpeptide ANG-(1-7) mimic AVE 0991 attenuates cardiac remodeling and improves baroreflex sensitivity in renovascular hypertensive rats. Life Sci 2013;92:266-275
-
(2013)
Life Sci
, vol.92
, pp. 266-275
-
-
Cunha, T.M.B.1
Lima, W.G.2
Silva, M.E.3
Souza Santos, R.A.4
Campagnole-Santos, M.J.5
Alzamora, A.C.6
-
56
-
-
84885155097
-
AVE 0991, a nonpeptide mimic of angiotensin(1-7) effects, attenuates pulmonary remodeling in a model of chronic asthma
-
Rodrigues-Machado MG, Magalhães GS, Cardoso JA, et al. AVE 0991, a nonpeptide mimic of angiotensin(1-7) effects, attenuates pulmonary remodeling in a model of chronic asthma. Br J Pharmacol 2013;170:835-846
-
(2013)
Br J Pharmacol
, vol.170
, pp. 835-846
-
-
Rodrigues-Machado, M.G.1
Magalhães, G.S.2
Cardoso, J.A.3
-
57
-
-
84874352641
-
Angiotensin-converting enzyme 2 priming enhances the function of endothelial progenitor cells and their therapeutic efficacy
-
Chen JXX, Xiao X, Chen S, et al. Angiotensin-converting enzyme 2 priming enhances the function of endothelial progenitor cells and their therapeutic efficacy. Hypertension 2013;61:681-689
-
(2013)
Hypertension
, vol.61
, pp. 681-689
-
-
Chen, J.X.X.1
Xiao, X.2
Chen, S.3
-
58
-
-
84878937766
-
Angiotensin-converting enzyme 2 activation improves endothelial function
-
Fraga-Silva RA, Costa-Fraga FP, Murça TM, et al. Angiotensin-converting enzyme 2 activation improves endothelial function. Hypertension 2013;61: 1233-1238
-
(2013)
Hypertension
, vol.61
, pp. 1233-1238
-
-
Fraga-Silva, R.A.1
Costa-Fraga, F.P.2
Murça, T.M.3
-
59
-
-
84875464297
-
Activation of the ACE2/ angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors
-
Jarajapu YPR, Bhatwadekar AD, Caballero S, et al. Activation of the ACE2/ angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors. Diabetes 2013;62:1258-1269
-
(2013)
Diabetes
, vol.62
, pp. 1258-1269
-
-
Jarajapu, Y.P.R.1
Bhatwadekar, A.D.2
Caballero, S.3
-
60
-
-
46249090611
-
Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis
-
Dong B, Zhang C, Feng JB, et al. Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis. Arterioscler Thromb Vasc Biol 2008;28:1270-1276
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1270-1276
-
-
Dong, B.1
Zhang, C.2
Feng, J.B.3
-
61
-
-
34648826015
-
ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts
-
Grobe JL, Der Sarkissian S, Stewart JM, Meszaros JG, Raizada MK, Katovich MJ. ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts. Clin Sci (Lond) 2007;113: 357-364
-
(2007)
Clin Sci (Lond)
, vol.113
, pp. 357-364
-
-
Grobe, J.L.1
Der Sarkissian, S.2
Stewart, J.M.3
Meszaros, J.G.4
Raizada, M.K.5
Katovich, M.J.6
-
63
-
-
79958792472
-
Exercise protects against myocardial ischemia-reperfusion injury via stimulation of b(3)-adrenergic receptors and increased nitric oxide signaling: Role of nitrite and nitrosothiols
-
Calvert JW, Condit ME, Aragón JP, et al. Exercise protects against myocardial ischemia-reperfusion injury via stimulation of b(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols. Circ Res 2011;108:1448-1458
-
(2011)
Circ Res
, vol.108
, pp. 1448-1458
-
-
Calvert, J.W.1
Condit, M.E.2
Aragón, J.P.3
-
64
-
-
80555142897
-
Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
-
Schenk S, McCurdy CE, Philp A, et al. Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J Clin Invest 2011;121: 4281-4288
-
(2011)
J Clin Invest
, vol.121
, pp. 4281-4288
-
-
Schenk, S.1
McCurdy, C.E.2
Philp, A.3
-
65
-
-
35349011597
-
Sirt1 modulates premature senescence-like phenotype in human endothelial cells
-
Ota H, Akishita M, Eto M, Iijima K, Kaneki M, Ouchi Y. Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J Mol Cell Cardiol 2007;43:571-579
-
(2007)
J Mol Cell Cardiol
, vol.43
, pp. 571-579
-
-
Ota, H.1
Akishita, M.2
Eto, M.3
Iijima, K.4
Kaneki, M.5
Ouchi, Y.6
-
66
-
-
35549008884
-
SIRT1 promotes endotheliumdependent vascular relaxation by activating endothelial nitric oxide synthase
-
Mattagajasingh I, Kim CS, Naqvi A, et al. SIRT1 promotes endotheliumdependent vascular relaxation by activating endothelial nitric oxide synthase. Proc Natl Acad Sci USA 2007;104:14855-14860
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14855-14860
-
-
Mattagajasingh, I.1
Kim, C.S.2
Naqvi, A.3
-
67
-
-
50649112638
-
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
-
Hou X, Xu S, Maitland-Toolan KA, et al. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J Biol Chem 2008;283:20015-20026
-
(2008)
J Biol Chem
, vol.283
, pp. 20015-20026
-
-
Hou, X.1
Xu, S.2
Maitland-Toolan, K.A.3
-
68
-
-
43049121395
-
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
-
Fulco M, Cen Y, Zhao P, et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell 2008;14:661-673
-
(2008)
Dev Cell
, vol.14
, pp. 661-673
-
-
Fulco, M.1
Cen, Y.2
Zhao, P.3
-
69
-
-
77953455149
-
Shear stress, SIRT1, and vascular homeostasis
-
Chen Z, Peng IC, Cui X, Li YS, Chien S, Shyy JYJ. Shear stress, SIRT1, and vascular homeostasis. Proc Natl Acad Sci USA 2010;107:10268-10273
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 10268-10273
-
-
Chen, Z.1
Peng, I.C.2
Cui, X.3
Li, Y.S.4
Chien, S.5
Shyy, J.Y.J.6
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