The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics

Cell Stress and Chaperones

Volumn 17, Issue 4, 2012, Pages 517-521

  Literáti Nagy, Zsuzsanna ^a   Tory, Kálmán ^b   Literáti Nagy, Botond ^c   Kolonics, Attila ^b   Török, Zsolt ^d   Gombos, Imre ^f   Balogh, Gábor ^d   Vígh Jr , László ^d,e   Horváth, Ibola ^d   Mandl, József ^a   Sümegi, Balázs ^f   Hooper, Philip L ^g   Vígh, László ^d  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b N Gene Research and Development Ltd   (Hungary)

^c Drug Research Center Ltd   (Hungary)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^e Mecsek Pharma Research Ltd   (Hungary)

^f UNIVERSITY OF PÉCS   (Hungary)

^g UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Atypical antipsychotic drugs; BGP 15; Diabetes; Heat shock proteins; HSP; HSP inducers; HSP72; Hydroxylamines; Insulin resistance; Insulin signaling; Membranes; Metabolic syndrome; Mitochondria; Schizophrenia; Side effects; Therapy; Weight gain

Indexed keywords

CLOZAPINE; GLUCOSE; HEAT SHOCK PROTEIN 72; LIPID; O (2 HYDROXY 3 PIPERIDINOPROPYL)NICOTINIC AMIDOXIME; OLANZAPINE; PLACEBO;

ADIPOCYTE; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LEVEL; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DOSE INCREASE; DRUG MECHANISM; FEMALE; GLUCOSE METABOLISM; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; LIPID METABOLISM; LIPID STORAGE; METABOLIC DISORDER; NONHUMAN; NORMAL HUMAN; PARALLEL DESIGN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RANDOMIZED CONTROLLED TRIAL; RAT; SOMNOLENCE; TREATMENT DURATION; WEIGHT CHANGE; WEIGHT GAIN;

ADIPOCYTES; ANIMALS; ANTIPSYCHOTIC AGENTS; CELLS, CULTURED; FEMALE; HSP72 HEAT-SHOCK PROTEINS; HUMANS; HYPOGLYCEMIC AGENTS; MALE; OXIMES; PIPERIDINES; RATS; RATS, WISTAR; UP-REGULATION; WEIGHT GAIN;

ANIMALIA; RATTUS NORVEGICUS; RODENTIA;

EID: 84865114015     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-012-0327-5     Document Type: Article

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