Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver

Diabetes

Volumn 62, Issue 3, 2013, Pages 811-824

  Otoda, Toshiki ^a   Takamura, Toshinari ^a   Misu, Hirofumi ^a   Ota, Tsuguhito ^a   Murata, Shigeo ^a   Hayashi, Hiroto ^a   Takayama, Hiroaki ^a   Kikuchi, Akihiro ^a   Kanamori, Takehiro ^a   Shima, Kosuke R ^a   Lan, Fei ^a,b   Takeda, Takashi ^a   Kurita, Seiichiro ^a   Ishikura, Kazuhide ^a   Kita, Yuki ^a   Iwayama, Kaito ^c   Kato, Ken Ichiro ^a   Uno, Masafumi ^a   Takeshita, Yumie ^a   Yamamoto, Miyuki ^a   Tokuyama, Kunpei ^c   Iseki, Shoichi ^a   Tanaka, Keiji ^d   Kaneko, Shuichi ^a   more..

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; GLUCOSE; INSULIN; PROTEASOME; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; GLUCONEOGENESIS; IN VIVO STUDY; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-OBESITY AGENTS; CELL LINE; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; LIVER; MALE; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MIDDLE AGED; MUSCLE, SKELETAL; OBESITY; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; RATS; UNFOLDED PROTEIN RESPONSE;

EID: 84874427117     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1652     Document Type: Article

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