Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance

Diabetes

Volumn 58, Issue 3, 2009, Pages 550-558

  Bruce, Clinton R ^a,b   Hoy, Andrew J ^b   Turner, Nigel ^b   Watt, Matthew J ^c,d   Allen, Tamara L ^a   Carpenter, Kevin ^e,f   Cooney, Gregory J ^b   Febbraio, Mark A ^a   Kraegen, Edward W ^b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^f UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; BETA ACTIN; CARNITINE PALMITOYLTRANSFERASE I; CITRATE SYNTHASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LONG CHAIN FATTY ACID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; PROTEIN KINASE C THETA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF1; TRIACYLGLYCEROL; CARNITINE PALMITOYLTRANSFERASE; FATTY ACID; PALMITIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; ELECTRON TRANSPORT; ENZYME ACTIVITY; EXTENSOR DIGITORUM LONGUS MUSCLE; FATTY ACID OXIDATION; HORMONE ACTION; HYPERINSULINEMIA; IN VIVO STUDY; INSULIN RESISTANCE; LIPID DIET; MALE; MUSCLE MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKELETAL MUSCLE; TIBIALIS ANTERIOR MUSCLE; ANIMAL; ELECTROPORATION; ENZYMOLOGY; FAT INTAKE; GENETICS; GLUCOSE CLAMP TECHNIQUE; HUMAN; HYPERINSULINISM; METABOLISM; MOTIVATION; PHYSIOLOGY; PLASMID; POLYMERASE CHAIN REACTION; SECOND MESSENGER; WISTAR RAT;

ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; DIETARY FATS; ELECTROPORATION; FATTY ACIDS; GLUCOSE CLAMP TECHNIQUE; HANDLING (PSYCHOLOGY); HUMANS; HYPERINSULINISM; INSULIN RESISTANCE; MALE; MITOCHONDRIA, MUSCLE; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; PALMITIC ACID; PLASMIDS; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; SECOND MESSENGER SYSTEMS;

EID: 62749140758     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-1078     Document Type: Article

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