메뉴 건너뛰기




Volumn 7, Issue 1, 2014, Pages 261-272

A clinical perspective on the role of chronic inflammation in gastrointestinal cancer

Author keywords

Carcinogenesis; Gastrointestinal cancer; Immune response; Inflammation; Risk factor

Indexed keywords


EID: 84905980016     PISSN: None     EISSN: 11787023     Source Type: Journal    
DOI: 10.2147/CEG.S43457     Document Type: Article
Times cited : (25)

References (154)
  • 2
    • 70249118103 scopus 로고    scopus 로고
    • Oesophageal cancer incidence in the United States by race, sex, and histologic type, 1977-2005
    • Cook MB, Chow WH, Devesa SS. Oesophageal cancer incidence in the United States by race, sex, and histologic type, 1977-2005. Br J Cancer. 2009;101(5):855-859.
    • (2009) Br J Cancer , vol.101 , Issue.5 , pp. 855-859
    • Cook, M.B.1    Chow, W.H.2    Devesa, S.S.3
  • 3
    • 49249109498 scopus 로고    scopus 로고
    • Liver is a target of arsenic carcinogenesis
    • Liu J, Waalkes MP. Liver is a target of arsenic carcinogenesis. Toxicol Sci. 2008;105(1):24-32.
    • (2008) Toxicol Sci , vol.105 , Issue.1 , pp. 24-32
    • Liu, J.1    Waalkes, M.P.2
  • 4
    • 31144461664 scopus 로고    scopus 로고
    • Helicobacter infection and gastric neoplasia
    • Peek RM Jr, Crabtree JE. Helicobacter infection and gastric neoplasia. J Pathol. 2006;208(2):233-248.
    • (2006) J Pathol , vol.208 , Issue.2 , pp. 233-248
    • Peek Jr., R.M.1    Crabtree, J.E.2
  • 6
    • 84965199448 scopus 로고
    • An address on the value of pathological experiments
    • Virchow R. An address on the value of pathological experiments. Br Med J. 1881;2(1075):198-203.
    • (1881) Br Med J , vol.2 , Issue.1075 , pp. 198-203
    • Virchow, R.1
  • 7
    • 84859384082 scopus 로고    scopus 로고
    • Innate lymphoid cells: Emerging insights in development, lineage relationships, and function
    • Spits H, Cupedo T. Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annu Rev Immunol. 2012;30:647-675.
    • (2012) Annu Rev Immunol , vol.30 , pp. 647-675
    • Spits, H.1    Cupedo, T.2
  • 8
    • 84872977452 scopus 로고    scopus 로고
    • Innate lymphoid cells - a proposal for uniform nomenclature
    • Spits H, Artis D, Colonna M, et al. Innate lymphoid cells - a proposal for uniform nomenclature. Nat Rev Immunol. 2013;13(2):145-149.
    • (2013) Nat Rev Immunol , vol.13 , Issue.2 , pp. 145-149
    • Spits, H.1    Artis, D.2    Colonna, M.3
  • 9
    • 0345131696 scopus 로고    scopus 로고
    • Clinical applications of TNF-alpha in cancer
    • Lejeune FJ, Rüegg C, Liénard D. Clinical applications of TNF-alpha in cancer. Curr Opin Immunol. 1998;10(5):573-580.
    • (1998) Curr Opin Immunol , vol.10 , Issue.5 , pp. 573-580
    • Lejeune, F.J.1    Rüegg, C.2    Liénard, D.3
  • 10
    • 33645318217 scopus 로고    scopus 로고
    • Diversification of T-helper-cell lineages: Finding the family root of IL-17-producing cells
    • Dong C. Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells. Nat Rev Immunol. 2006;6(4):329-333.
    • (2006) Nat Rev Immunol , vol.6 , Issue.4 , pp. 329-333
    • Dong, C.1
  • 11
    • 0028288179 scopus 로고
    • Lymphokine production by human T cells in disease states
    • Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol. 1994;12:227-257.
    • (1994) Annu Rev Immunol , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 12
    • 67349234068 scopus 로고    scopus 로고
    • IL-17 and Th17 cells in human inflammatory diseases
    • Miossec P. IL-17 and Th17 cells in human inflammatory diseases. Microbes Infect. 2009;11(5):625-630.
    • (2009) Microbes Infect , vol.11 , Issue.5 , pp. 625-630
    • Miossec, P.1
  • 14
    • 0033831517 scopus 로고    scopus 로고
    • Infections as a major preventable cause of human cancer
    • Kuper H, Adami HO, Trichopoulos D. Infections as a major preventable cause of human cancer. J Intern Med. 2000;248(3):171-183.
    • (2000) J Intern Med , vol.248 , Issue.3 , pp. 171-183
    • Kuper, H.1    Adami, H.O.2    Trichopoulos, D.3
  • 15
    • 84861648384 scopus 로고    scopus 로고
    • Global burden of cancers attributable to infections in 2008: A review and synthetic analysis
    • de Martel C, Ferlay J, Franceschi S, et al. Global burden of cancers attributable to infections in 2008: a review and synthetic analysis. Lancet Oncol. 2012;13(6):607-615.
    • (2012) Lancet Oncol , vol.13 , Issue.6 , pp. 607-615
    • de Martel, C.1    Ferlay, J.2    Franceschi, S.3
  • 16
    • 0032112771 scopus 로고    scopus 로고
    • Nitric oxide and oxygen radicals in infection, inflammation, and cancer
    • Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistry (Mosc). 1998;63(7):854-865.
    • (1998) Biochemistry (Mosc) , vol.63 , Issue.7 , pp. 854-865
    • Maeda, H.1    Akaike, T.2
  • 17
    • 0033969322 scopus 로고    scopus 로고
    • Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism
    • Jaiswal M, LaRusso NF, Burgart LJ, Gores GJ. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res. 2000;60(1): 184-190.
    • (2000) Cancer Res , vol.60 , Issue.1 , pp. 184-190
    • Jaiswal, M.1    Larusso, N.F.2    Burgart, L.J.3    Gores, G.J.4
  • 18
    • 0036082617 scopus 로고    scopus 로고
    • Oxidative stress inactivates the human DNA mismatch repair system
    • Chang CL, Marra G, Chauhan DP, et al. Oxidative stress inactivates the human DNA mismatch repair system. Am J Physiol Cell Physiol. 2002;283(1):C148-C154.
    • (2002) Am J Physiol Cell Physiol , vol.283 , Issue.1
    • Chang, C.L.1    Marra, G.2    Chauhan, D.P.3
  • 19
    • 0034282793 scopus 로고    scopus 로고
    • Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1
    • Fleisher AS, Esteller M, Harpaz N, et al. Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Res. 2000;60(17):4864-4868.
    • (2000) Cancer Res , vol.60 , Issue.17 , pp. 4864-4868
    • Fleisher, A.S.1    Esteller, M.2    Harpaz, N.3
  • 20
    • 15244344206 scopus 로고    scopus 로고
    • HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression
    • Koshiji M, To KK, Hammer S, et al. HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression. Mol Cell. 2005;17(6):793-803.
    • (2005) Mol Cell , vol.17 , Issue.6 , pp. 793-803
    • Koshiji, M.1    To, K.K.2    Hammer, S.3
  • 21
    • 0347334750 scopus 로고    scopus 로고
    • IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
    • Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J. 2003;17(14):2115-2117.
    • (2003) FASEB J , vol.17 , Issue.14 , pp. 2115-2117
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Neckers, L.5
  • 22
    • 51249087746 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers
    • Endo Y, Marusawa H, Kou T, et al. Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. Gastroenterology. 2008;135(3):889-898, 898. e1-e3.
    • (2008) Gastroenterology , vol.135 , Issue.3 , pp. 889-898
    • Endo, Y.1    Marusawa, H.2    Kou, T.3
  • 25
    • 0034704880 scopus 로고    scopus 로고
    • Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    • El-Omar EM, Carrington M, Chow WH, et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature. 2000;404(6776):398-402.
    • (2000) Nature , vol.404 , Issue.6776 , pp. 398-402
    • El-Omar, E.M.1    Carrington, M.2    Chow, W.H.3
  • 26
    • 36549082403 scopus 로고    scopus 로고
    • Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors
    • Fukata M, Chen A, Vamadevan AS, et al. Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors. Gastroenterology. 2007;133(6):1869-1881.
    • (2007) Gastroenterology , vol.133 , Issue.6 , pp. 1869-1881
    • Fukata, M.1    Chen, A.2    Vamadevan, A.S.3
  • 27
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer. 2009;9(11):798-809.
    • (2009) Nat Rev Cancer , vol.9 , Issue.11 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 28
    • 58649101347 scopus 로고    scopus 로고
    • gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
    • Bollrath J, Phesse TJ, von Burstin VA, et al. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell. 2009;15(2):91-102.
    • (2009) Cancer Cell , vol.15 , Issue.2 , pp. 91-102
    • Bollrath, J.1    Phesse, T.J.2    von Burstin, V.A.3
  • 29
    • 79955030498 scopus 로고    scopus 로고
    • Border patrol: Regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
    • Sonnenberg GF, Fouser LA, Artis D. Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat Immunol. 2011;12(5):383-390.
    • (2011) Nat Immunol , vol.12 , Issue.5 , pp. 383-390
    • Sonnenberg, G.F.1    Fouser, L.A.2    Artis, D.3
  • 30
    • 79960055459 scopus 로고    scopus 로고
    • RAS interaction with PI3K: More than just another effector pathway
    • Castellano E, Downward J. RAS interaction with PI3K: more than just another effector pathway. Genes Cancer. 2011;2(3):261-274.
    • (2011) Genes Cancer , vol.2 , Issue.3 , pp. 261-274
    • Castellano, E.1    Downward, J.2
  • 32
    • 84881053737 scopus 로고    scopus 로고
    • Clinical utility of anti-p53 auto-antibody: Systematic review and focus on colorectal cancer
    • Suppiah A, Greenman J. Clinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancer. World J Gastroenterol. 2013;19(29):4651-4670.
    • (2013) World J Gastroenterol , vol.19 , Issue.29 , pp. 4651-4670
    • Suppiah, A.1    Greenman, J.2
  • 33
    • 84872406787 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer
    • Liang J, Nagahashi M, Kim EY, et al. Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. Cancer Cell. 2013;23(1): 107-120.
    • (2013) Cancer Cell , vol.23 , Issue.1 , pp. 107-120
    • Liang, J.1    Nagahashi, M.2    Kim, E.Y.3
  • 34
    • 77953136143 scopus 로고    scopus 로고
    • TNF receptor 2 pathway: Drug target for autoimmune diseases
    • Faustman D, Davis M. TNF receptor 2 pathway: drug target for autoimmune diseases. Nat Rev Drug Discov. 2010;9(6):482-493.
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.6 , pp. 482-493
    • Faustman, D.1    Davis, M.2
  • 35
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation
    • Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation. Cell. 2009;139(4):693-706.
    • (2009) Cell , vol.139 , Issue.4 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 36
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-kappaB as the matchmaker
    • Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol. 2011;12(8):715-723.
    • (2011) Nat Immunol , vol.12 , Issue.8 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 37
    • 84872600554 scopus 로고    scopus 로고
    • Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
    • Schwitalla S, Fingerle AA, Cammareri P, et al. Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. Cell. 2013;152(1-2):25-38.
    • (2013) Cell , vol.152 , Issue.1-2 , pp. 25-38
    • Schwitalla, S.1    Fingerle, A.A.2    Cammareri, P.3
  • 38
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 2004;118(3):285-296.
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 39
    • 33645999706 scopus 로고    scopus 로고
    • NF-kappaB and IKK as therapeutic targets in cancer
    • Kim HJ, Hawke N, Baldwin AS. NF-kappaB and IKK as therapeutic targets in cancer. Cell Death Differ. 2006;13(5):738-747.
    • (2006) Cell Death Differ , vol.13 , Issue.5 , pp. 738-747
    • Kim, H.J.1    Hawke, N.2    Baldwin, A.S.3
  • 40
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 41
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev. 2004;25(4):581-611.
    • (2004) Endocr Rev , vol.25 , Issue.4 , pp. 581-611
    • Ferrara, N.1
  • 42
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • Murdoch C, Muthana M, Coffelt SB, Lewis CE. The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer. 2008;8(8):618-631.
    • (2008) Nat Rev Cancer , vol.8 , Issue.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 43
    • 0032800759 scopus 로고    scopus 로고
    • The role of CXC chemokines in the regulation of angiogenesis
    • Keane MP, Strieter RM. The role of CXC chemokines in the regulation of angiogenesis. Chem Immunol. 1999;72:86-101.
    • (1999) Chem Immunol , vol.72 , pp. 86-101
    • Keane, M.P.1    Strieter, R.M.2
  • 44
    • 0034650795 scopus 로고    scopus 로고
    • Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNFalpha and IL-1alpha
    • Torisu H, Ono M, Kiryu H, et al. Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalpha and IL-1alpha. Int J Cancer. 2000;85(2):182-188.
    • (2000) Int J Cancer , vol.85 , Issue.2 , pp. 182-188
    • Torisu, H.1    Ono, M.2    Kiryu, H.3
  • 45
    • 79952070774 scopus 로고    scopus 로고
    • The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
    • Peinado H, Lavotshkin S, Lyden D. The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts. Semin Cancer Biol. 2011;21(2):139-146.
    • (2011) Semin Cancer Biol , vol.21 , Issue.2 , pp. 139-146
    • Peinado, H.1    Lavotshkin, S.2    Lyden, D.3
  • 46
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell. 2010;141(1):39-51.
    • (2010) Cell , vol.141 , Issue.1 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 47
    • 12944254582 scopus 로고    scopus 로고
    • IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1
    • Vidal-Vanaclocha F, Fantuzzi G, Mendoza L, et al. IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci U S A. 2000;97(2):734-739.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.2 , pp. 734-739
    • Vidal-Vanaclocha, F.1    Fantuzzi, G.2    Mendoza, L.3
  • 48
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009;119(6):1420-1428.
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 49
    • 76949084622 scopus 로고    scopus 로고
    • TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
    • Wu Y, Zhou BP. TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br J Cancer. 2010;102(4):639-644.
    • (2010) Br J Cancer , vol.102 , Issue.4 , pp. 639-644
    • Wu, Y.1    Zhou, B.P.2
  • 50
    • 69249221254 scopus 로고    scopus 로고
    • Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells
    • Sullivan NJ, Sasser AK, Axel AE, et al. Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells. Oncogene. 2009;28(33):2940-2947.
    • (2009) Oncogene , vol.28 , Issue.33 , pp. 2940-2947
    • Sullivan, N.J.1    Sasser, A.K.2    Axel, A.E.3
  • 51
    • 84874217880 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer
    • Wang H, Wang HS, Zhou BH, et al. Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer. PLoS One. 2013;8(2):e56664.
    • (2013) PLoS One , vol.8 , Issue.2
    • Wang, H.1    Wang, H.S.2    Zhou, B.H.3
  • 52
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell. 2009;15(5):416-428.
    • (2009) Cancer Cell , vol.15 , Issue.5 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 53
    • 84866334922 scopus 로고    scopus 로고
    • TGF-β-induced epithelial-mesenchymal transition: A link between cancer and inflammation
    • Fuxe J, Karlsson MC. TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation. Semin Cancer Biol. 2012;22(5-6):455-461.
    • (2012) Semin Cancer Biol , vol.22 , Issue.5-6 , pp. 455-461
    • Fuxe, J.1    Karlsson, M.C.2
  • 54
    • 0030879456 scopus 로고    scopus 로고
    • Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression
    • Elder DJ, Halton DE, Hague A, Paraskeva C. Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. Clin Cancer Res. 1997;3(10):1679-1683.
    • (1997) Clin Cancer Res , vol.3 , Issue.10 , pp. 1679-1683
    • Elder, D.J.1    Halton, D.E.2    Hague, A.3    Paraskeva, C.4
  • 55
    • 0035183413 scopus 로고    scopus 로고
    • Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs
    • García-Rodríguez LA, Huerta-Alvarez C. Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs. Epidemiology. 2001;12(1):88-93.
    • (2001) Epidemiology , vol.12 , Issue.1 , pp. 88-93
    • García-Rodríguez, L.A.1    Huerta-Alvarez, C.2
  • 56
    • 0035496616 scopus 로고    scopus 로고
    • Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
    • Gupta RA, Dubois RN. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat Rev Cancer. 2001;1(1):11-21.
    • (2001) Nat Rev Cancer , vol.1 , Issue.1 , pp. 11-21
    • Gupta, R.A.1    Dubois, R.N.2
  • 57
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
    • Yin MJ, Yamamoto Y, Gaynor RB. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998;396(6706):77-80.
    • (1998) Nature , vol.396 , Issue.6706 , pp. 77-80
    • Yin, M.J.1    Yamamoto, Y.2    Gaynor, R.B.3
  • 59
    • 84891106411 scopus 로고    scopus 로고
    • COX-independent mechanisms of cancer chemoprevention by anti-inflammatory drugs
    • Gurpinar E, Grizzle WE, Piazza GA. COX-independent mechanisms of cancer chemoprevention by anti-inflammatory drugs. Front Oncol. 2013;3:181.
    • (2013) Front Oncol , vol.3 , pp. 181
    • Gurpinar, E.1    Grizzle, W.E.2    Piazza, G.A.3
  • 60
  • 61
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med. 2013;19(11):1423-1437.
    • (2013) Nat Med , vol.19 , Issue.11 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 62
    • 84879604746 scopus 로고    scopus 로고
    • The metastasis-promoting roles of tumor-associated immune cells
    • Smith HA, Kang Y. The metastasis-promoting roles of tumor-associated immune cells. J Mol Med (Berl). 2013;91(4):411-429.
    • (2013) J Mol Med (Berl) , vol.91 , Issue.4 , pp. 411-429
    • Smith, H.A.1    Kang, Y.2
  • 63
    • 0033067163 scopus 로고    scopus 로고
    • Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
    • Leek RD, Landers RJ, Harris AL, Lewis CE. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br J Cancer. 1999;79(5-6):991-995.
    • (1999) Br J Cancer , vol.79 , Issue.5-6 , pp. 991-995
    • Leek, R.D.1    Landers, R.J.2    Harris, A.L.3    Lewis, C.E.4
  • 64
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich DI, Chen HL, Girgis KR, et al. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med. 1996;2(10):1096-1103.
    • (1996) Nat Med , vol.2 , Issue.10 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3
  • 65
    • 0033561648 scopus 로고    scopus 로고
    • TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells
    • Geissmann F, Revy P, Regnault A, et al. TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells. J Immunol. 1999;162(8):4567-4575.
    • (1999) J Immunol , vol.162 , Issue.8 , pp. 4567-4575
    • Geissmann, F.1    Revy, P.2    Regnault, A.3
  • 66
    • 34248328368 scopus 로고    scopus 로고
    • CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers
    • Huang B, Lei Z, Zhao J, et al. CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers. Cancer Lett. 2007; 252(1):86-92.
    • (2007) Cancer Lett , vol.252 , Issue.1 , pp. 86-92
    • Huang, B.1    Lei, Z.2    Zhao, J.3
  • 67
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009;9(3):162-174.
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 68
    • 84872559040 scopus 로고    scopus 로고
    • The immunosuppressive tumour network: Myeloid-derived suppressor cells, regulatory T cells and natural killer T cells
    • Lindau D, Gielen P, Kroesen M, Wesseling P, Adema GJ. The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells. Immunology. 2013;138(2): 105-115.
    • (2013) Immunology , vol.138 , Issue.2 , pp. 105-115
    • Lindau, D.1    Gielen, P.2    Kroesen, M.3    Wesseling, P.4    Adema, G.J.5
  • 69
    • 77952513628 scopus 로고    scopus 로고
    • Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma
    • Zhai R, Chen F, Liu G, et al. Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma. J Clin Oncol. 2010;28(14):2445-2451.
    • (2010) J Clin Oncol , vol.28 , Issue.14 , pp. 2445-2451
    • Zhai, R.1    Chen, F.2    Liu, G.3
  • 70
    • 84862909168 scopus 로고    scopus 로고
    • Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia
    • Quante M, Bhagat G, Abrams JA, et al. Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell. 2012;21(1):36-51.
    • (2012) Cancer Cell , vol.21 , Issue.1 , pp. 36-51
    • Quante, M.1    Bhagat, G.2    Abrams, J.A.3
  • 71
    • 38049187779 scopus 로고    scopus 로고
    • Bone marrow progenitor cells contribute to esophageal regeneration and metaplasia in a rat model of Barrett's esophagus
    • Sarosi G, Brown G, Jaiswal K, et al. Bone marrow progenitor cells contribute to esophageal regeneration and metaplasia in a rat model of Barrett's esophagus. Dis Esophagus. 2008;21(1):43-50.
    • (2008) Dis Esophagus , vol.21 , Issue.1 , pp. 43-50
    • Sarosi, G.1    Brown, G.2    Jaiswal, K.3
  • 72
    • 79959631111 scopus 로고    scopus 로고
    • Residual embryonic cells as precursors of a Barrett's-like metaplasia
    • Wang X, Ouyang H, Yamamoto Y, et al. Residual embryonic cells as precursors of a Barrett's-like metaplasia. Cell. 2011;145(7):1023-1035.
    • (2011) Cell , vol.145 , Issue.7 , pp. 1023-1035
    • Wang, X.1    Ouyang, H.2    Yamamoto, Y.3
  • 73
    • 0036716699 scopus 로고    scopus 로고
    • Inflammatory gradient in Barrett's oesophagus: Implications for disease complications
    • Fitzgerald RC, Abdalla S, Onwuegbusi BA, et al. Inflammatory gradient in Barrett's oesophagus: implications for disease complications. Gut. 2002;51(3):316-322.
    • (2002) Gut , vol.51 , Issue.3 , pp. 316-322
    • Fitzgerald, R.C.1    Abdalla, S.2    Onwuegbusi, B.A.3
  • 75
    • 77954726942 scopus 로고    scopus 로고
    • Risk of malignant progression in patients with Barrett's oesophagus: A Dutch nationwide cohort study
    • de Jonge PJ, van Blankenstein M, Looman CW, Casparie MK, Meijer GA, Kuipers EJ. Risk of malignant progression in patients with Barrett's oesophagus: a Dutch nationwide cohort study. Gut. 2010;59(8):1030-1036.
    • (2010) Gut , vol.59 , Issue.8 , pp. 1030-1036
    • de Jonge, P.J.1    van Blankenstein, M.2    Looman, C.W.3    Casparie, M.K.4    Meijer, G.A.5    Kuipers, E.J.6
  • 77
    • 0035168386 scopus 로고    scopus 로고
    • Etiology and chemoprevention of esophageal squamous cell carcinoma
    • Stoner GD, Gupta A. Etiology and chemoprevention of esophageal squamous cell carcinoma. Carcinogenesis. 2001;22(11):1737-1746.
    • (2001) Carcinogenesis , vol.22 , Issue.11 , pp. 1737-1746
    • Stoner, G.D.1    Gupta, A.2
  • 78
    • 80855143718 scopus 로고    scopus 로고
    • Meta-analysis: Non-steroidal anti-inflammatory drug use and the risk of esophageal squamous cell carcinoma
    • Sun L, Yu S. Meta-analysis: non-steroidal anti-inflammatory drug use and the risk of esophageal squamous cell carcinoma. Dis Esophagus. 2011;24(8):544-549.
    • (2011) Dis Esophagus , vol.24 , Issue.8 , pp. 544-549
    • Sun, L.1    Yu, S.2
  • 79
    • 84883851981 scopus 로고    scopus 로고
    • Epidemiology of esophageal cancer
    • Zhang Y. Epidemiology of esophageal cancer. World J Gastroenterol. 2013;19(34):5598-5606.
    • (2013) World J Gastroenterol , vol.19 , Issue.34 , pp. 5598-5606
    • Zhang, Y.1
  • 80
    • 79955478213 scopus 로고    scopus 로고
    • Helicobacter pylori in the pathogenesis of gastric cancer and gastric lymphoma
    • Kim SS, Ruiz VE, Carroll JD, Moss SF. Helicobacter pylori in the pathogenesis of gastric cancer and gastric lymphoma. Cancer Lett. 2011;305(2):228-238.
    • (2011) Cancer Lett , vol.305 , Issue.2 , pp. 228-238
    • Kim, S.S.1    Ruiz, V.E.2    Carroll, J.D.3    Moss, S.F.4
  • 81
    • 84869170531 scopus 로고    scopus 로고
    • Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention
    • Nagini S. Carcinoma of the stomach: a review of epidemiology, pathogenesis, molecular genetics and chemoprevention. World J Gastrointest Oncol. 2012;4(7):156-169.
    • (2012) World J Gastrointest Oncol , vol.4 , Issue.7 , pp. 156-169
    • Nagini, S.1
  • 82
    • 84889589086 scopus 로고    scopus 로고
    • Helicobacter pylori and interleukin-8 in gastric cancer
    • Lee KE, Khoi PN, Xia Y, et al. Helicobacter pylori and interleukin-8 in gastric cancer. World J Gastroenterol. 2013;19(45):8192-8202.
    • (2013) World J Gastroenterol , vol.19 , Issue.45 , pp. 8192-8202
    • Lee, K.E.1    Khoi, P.N.2    Xia, Y.3
  • 83
    • 4544334936 scopus 로고    scopus 로고
    • Oncogenic mechanisms of the Helicobacter pylori CagA protein
    • Hatakeyama M. Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer. 2004;4(9):688-694.
    • (2004) Nat Rev Cancer , vol.4 , Issue.9 , pp. 688-694
    • Hatakeyama, M.1
  • 84
    • 84896737881 scopus 로고    scopus 로고
    • A positive feedback loop between STAT3 and cyclooxygenase-2 gene may contribute to Helicobacter pylori-associated human gastric tumorigenesis
    • Xiong H, Du W, Sun TT, et al. A positive feedback loop between STAT3 and cyclooxygenase-2 gene may contribute to Helicobacter pylori-associated human gastric tumorigenesis. Int J Cancer. 2014;134(9):2030-2040.
    • (2014) Int J Cancer , vol.134 , Issue.9 , pp. 2030-2040
    • Xiong, H.1    Du, W.2    Sun, T.T.3
  • 86
    • 84876005485 scopus 로고    scopus 로고
    • Autoimmune gastritis mediated by CD4+ T cells promotes the development of gastric cancer
    • Nguyen TL, Khurana SS, Bellone CJ, et al. Autoimmune gastritis mediated by CD4+ T cells promotes the development of gastric cancer. Cancer Res. 2013;73(7):2117-2126.
    • (2013) Cancer Res , vol.73 , Issue.7 , pp. 2117-2126
    • Nguyen, T.L.1    Khurana, S.S.2    Bellone, C.J.3
  • 87
    • 84874105291 scopus 로고    scopus 로고
    • The role of PGE2-associated inflammatory responses in gastric cancer development
    • Oshima H, Oshima M. The role of PGE2-associated inflammatory responses in gastric cancer development. Semin Immunopathol. 2013;35(2):139-150.
    • (2013) Semin Immunopathol , vol.35 , Issue.2 , pp. 139-150
    • Oshima, H.1    Oshima, M.2
  • 88
    • 84905992135 scopus 로고    scopus 로고
    • TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells. Oncogene
    • Oshima H, Ishikawa T, Yoshida GJ, et al. TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells. Oncogene. Epub August 26, 2013.
    • (2013) Epub August , pp. 26
    • Oshima, H.1    Ishikawa, T.2    Yoshida, G.J.3
  • 89
    • 84876094509 scopus 로고    scopus 로고
    • Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis
    • Kinoshita H, Hirata Y, Nakagawa H, et al. Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis. PLoS One. 2013;8(4):e60914.
    • (2013) PLoS One , vol.8 , Issue.4
    • Kinoshita, H.1    Hirata, Y.2    Nakagawa, H.3
  • 90
    • 84865624014 scopus 로고    scopus 로고
    • Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells
    • Kong D, Piao YS, Yamashita S, et al. Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. Oncogene. 2012;31(35):3949-3960.
    • (2012) Oncogene , vol.31 , Issue.35 , pp. 3949-3960
    • Kong, D.1    Piao, Y.S.2    Yamashita, S.3
  • 93
    • 35449002488 scopus 로고    scopus 로고
    • Carcinogenesis in inflammatory bowel disease
    • Herszenyi L, Miheller P, Tulassay Z. Carcinogenesis in inflammatory bowel disease. Dig Dis. 2007;25(3):267-269.
    • (2007) Dig Dis , vol.25 , Issue.3 , pp. 267-269
    • Herszenyi, L.1    Miheller, P.2    Tulassay, Z.3
  • 94
    • 84864859115 scopus 로고    scopus 로고
    • Colorectal cancer in inflammatory bowel disease: What is the real magnitude of the risk?
    • Dyson JK, Rutter MD. Colorectal cancer in inflammatory bowel disease: what is the real magnitude of the risk? World J Gastroenterol. 2012;18(29):3839-3848.
    • (2012) World J Gastroenterol , vol.18 , Issue.29 , pp. 3839-3848
    • Dyson, J.K.1    Rutter, M.D.2
  • 95
    • 84896713816 scopus 로고    scopus 로고
    • Chronic ulcerative colitis and colorectal cancer
    • Rogler G. Chronic ulcerative colitis and colorectal cancer. Cancer Lett. 2014;345(2):235-241.
    • (2014) Cancer Lett , vol.345 , Issue.2 , pp. 235-241
    • Rogler, G.1
  • 96
    • 84887171375 scopus 로고    scopus 로고
    • E. coli and colon cancer: Is mutY a culprit?
    • Khan AA, Cash P. E. coli and colon cancer: is mutY a culprit? Cancer Lett. 2013;341(2):127-131.
    • (2013) Cancer Lett , vol.341 , Issue.2 , pp. 127-131
    • Khan, A.A.1    Cash, P.2
  • 97
    • 84880102029 scopus 로고    scopus 로고
    • Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: Clinico-pathogenic aspects
    • Füri I, Sipos F, Germann TM, et al. Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: clinico-pathogenic aspects. World J Gastroenterol. 2013;19(26):4119-4126.
    • (2013) World J Gastroenterol , vol.19 , Issue.26 , pp. 4119-4126
    • Füri, I.1    Sipos, F.2    Germann, T.M.3
  • 98
    • 84873930620 scopus 로고    scopus 로고
    • Regulatory T cells in inflammatory bowel diseases and colorectal cancer
    • Müzes G, Molnár B, Sipos F. Regulatory T cells in inflammatory bowel diseases and colorectal cancer. World J Gastroenterol. 2012;18(40):5688-5694.
    • (2012) World J Gastroenterol , vol.18 , Issue.40 , pp. 5688-5694
    • Müzes, G.1    Molnár, B.2    Sipos, F.3
  • 99
    • 3242724146 scopus 로고    scopus 로고
    • Inflammation and cancer V. Chronic pancreatitis and pancreatic cancer
    • Whitcomb DC. Inflammation and cancer V. Chronic pancreatitis and pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2004;287(2):G315-G319.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , Issue.2
    • Whitcomb, D.C.1
  • 100
    • 84902124992 scopus 로고    scopus 로고
    • The immune network in pancreatic cancer development and progression
    • Wörmann SM, Diakopoulos KN, Lesina M, Algül H. The immune network in pancreatic cancer development and progression. Oncogene. 2014;33(23):2956-2967.
    • (2014) Oncogene , vol.33 , Issue.23 , pp. 2956-2967
    • Wörmann, S.M.1    Diakopoulos, K.N.2    Lesina, M.3    Algül, H.4
  • 102
    • 0032960393 scopus 로고    scopus 로고
    • Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer
    • Kleeff J, Kusama T, Rossi DL, et al. Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer. Int J Cancer. 1999;81(4):650-657.
    • (1999) Int J Cancer , vol.81 , Issue.4 , pp. 650-657
    • Kleeff, J.1    Kusama, T.2    Rossi, D.L.3
  • 103
    • 0033670393 scopus 로고    scopus 로고
    • A polymorphism of the interleukin-1 beta gene influences survival in pancreatic cancer
    • Barber MD, Powell JJ, Lynch SF, Fearon KC, Ross JA. A polymorphism of the interleukin-1 beta gene influences survival in pancreatic cancer. Br J Cancer. 2000;83(11):1443-1447.
    • (2000) Br J Cancer , vol.83 , Issue.11 , pp. 1443-1447
    • Barber, M.D.1    Powell, J.J.2    Lynch, S.F.3    Fearon, K.C.4    Ross, J.A.5
  • 104
    • 84891110745 scopus 로고    scopus 로고
    • Risk factors and therapeutic targets in pancreatic cancer
    • Wörmann SM, Algül H. Risk factors and therapeutic targets in pancreatic cancer. Front Oncol. 2013;3:282.
    • (2013) Front Oncol , vol.3 , pp. 282
    • Wörmann, S.M.1    Algül, H.2
  • 105
    • 84893436855 scopus 로고    scopus 로고
    • Risk factors for pancreatic cancer: Underlying mechanisms and potential targets
    • Kolodecik T, Shugrue C, Ashat M, Thrower EC. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Front Physiol. 2013;4:415.
    • (2013) Front Physiol , vol.4 , pp. 415
    • Kolodecik, T.1    Shugrue, C.2    Ashat, M.3    Thrower, E.C.4
  • 106
    • 0036093865 scopus 로고    scopus 로고
    • Inflammation and the development of pancreatic cancer
    • Farrow B, Evers BM. Inflammation and the development of pancreatic cancer. Surg Oncol. 2002;10(4):153-169.
    • (2002) Surg Oncol , vol.10 , Issue.4 , pp. 153-169
    • Farrow, B.1    Evers, B.M.2
  • 107
    • 12644290242 scopus 로고    scopus 로고
    • Analysis of K-ras oncogene mutations in chronic pancreatitis with ductal hyperplasia
    • Rivera JA, Rall CJ, Graeme-Cook F, et al. Analysis of K-ras oncogene mutations in chronic pancreatitis with ductal hyperplasia. Surgery. 1997;121(1):42-49.
    • (1997) Surgery , vol.121 , Issue.1 , pp. 42-49
    • Rivera, J.A.1    Rall, C.J.2    Graeme-Cook, F.3
  • 108
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo M. Pancreatic cancer. N Engl J Med. 2010;362(17): 1605-1617.
    • (2010) N Engl J Med , vol.362 , Issue.17 , pp. 1605-1617
    • Hidalgo, M.1
  • 109
    • 34447506658 scopus 로고    scopus 로고
    • Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
    • Ancrile B, Lim KH, Counter CM. Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. Genes Dev. 2007;21(14): 1714-1719.
    • (2007) Genes Dev , vol.21 , Issue.14 , pp. 1714-1719
    • Ancrile, B.1    Lim, K.H.2    Counter, C.M.3
  • 110
    • 84862150896 scopus 로고    scopus 로고
    • Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer
    • Bayne LJ, Beatty GL, Jhala N, et al. Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. Cancer Cell. 2012;21(6):822-835.
    • (2012) Cancer Cell , vol.21 , Issue.6 , pp. 822-835
    • Bayne, L.J.1    Beatty, G.L.2    Jhala, N.3
  • 111
    • 84862147254 scopus 로고    scopus 로고
    • Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
    • Pylayeva-Gupta Y, Lee KE, Hajdu CH, Miller G, Bar-Sagi D. Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell. 2012;21(6):836-847.
    • (2012) Cancer Cell , vol.21 , Issue.6 , pp. 836-847
    • Pylayeva-Gupta, Y.1    Lee, K.E.2    Hajdu, C.H.3    Miller, G.4    Bar-Sagi, D.5
  • 112
    • 79953154967 scopus 로고    scopus 로고
    • CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
    • Beatty GL, Chiorean EG, Fishman MP, et al. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science. 2011;331(6024):1612-1616.
    • (2011) Science , vol.331 , Issue.6024 , pp. 1612-1616
    • Beatty, G.L.1    Chiorean, E.G.2    Fishman, M.P.3
  • 113
    • 79953756112 scopus 로고    scopus 로고
    • Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
    • Lesina M, Kurkowski MU, Ludes K, et al. Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. Cancer Cell. 2011;19(4):456-469.
    • (2011) Cancer Cell , vol.19 , Issue.4 , pp. 456-469
    • Lesina, M.1    Kurkowski, M.U.2    Ludes, K.3
  • 114
    • 84885093561 scopus 로고    scopus 로고
    • Role of bacterial infections in pancreatic cancer
    • Michaud DS. Role of bacterial infections in pancreatic cancer. Carcinogenesis. 2013;34(10):2193-2197.
    • (2013) Carcinogenesis , vol.34 , Issue.10 , pp. 2193-2197
    • Michaud, D.S.1
  • 115
    • 7044264264 scopus 로고    scopus 로고
    • Hepatitis C infection and the increasing incidence of hepatocellular carcinoma: A population-based study
    • Davila JA, Morgan RO, Shaib Y, McGlynn KA, El-Serag HB. Hepatitis C infection and the increasing incidence of hepatocellular carcinoma: a population-based study. Gastroenterology. 2004;127(5):1372-1380.
    • (2004) Gastroenterology , vol.127 , Issue.5 , pp. 1372-1380
    • Davila, J.A.1    Morgan, R.O.2    Shaib, Y.3    McGlynn, K.A.4    El-Serag, H.B.5
  • 116
    • 84883137078 scopus 로고    scopus 로고
    • HBV induced HCC: Major risk factors from genetic to molecular level
    • Ayub A, Ashfaq UA, Haque A. HBV induced HCC: major risk factors from genetic to molecular level. Biomed Res Int. 2013; 2013:810461.
    • (2013) Biomed Res Int , pp. 810461
    • Ayub, A.1    Ashfaq, U.A.2    Haque, A.3
  • 117
    • 33845420396 scopus 로고    scopus 로고
    • The role of cytokines in hepatocellular carcinoma
    • Budhu A, Wang XW. The role of cytokines in hepatocellular carcinoma. J Leukoc Biol. 2006;80(6):1197-1213.
    • (2006) J Leukoc Biol , vol.80 , Issue.6 , pp. 1197-1213
    • Budhu, A.1    Wang, X.W.2
  • 118
    • 84871842657 scopus 로고    scopus 로고
    • Epidemiology and surveillance of hepatocellular carcinoma
    • Kim do Y, Han KH. Epidemiology and surveillance of hepatocellular carcinoma. Liver Cancer. 2012;1(1):2-14.
    • (2012) Liver Cancer , vol.1 , Issue.1 , pp. 2-14
    • Kim, D.Y.1    Han, K.H.2
  • 119
    • 34347232205 scopus 로고    scopus 로고
    • Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma
    • Matsuzaki K, Murata M, Yoshida K, et al. Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma. Hepatology. 2007;46(1):48-57.
    • (2007) Hepatology , vol.46 , Issue.1 , pp. 48-57
    • Matsuzaki, K.1    Murata, M.2    Yoshida, K.3
  • 120
    • 78851469544 scopus 로고    scopus 로고
    • Does antiviral therapy for hepatitis B and C prevent hepatocellular carcinoma?
    • Lok AS. Does antiviral therapy for hepatitis B and C prevent hepatocellular carcinoma? J Gastroenterol Hepatol. 2011;26(2):221-227.
    • (2011) J Gastroenterol Hepatol , vol.26 , Issue.2 , pp. 221-227
    • Lok, A.S.1
  • 121
    • 84873726893 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of hepatocellular carcinoma: An update
    • Aravalli RN, Cressman EN, Steer CJ. Cellular and molecular mechanisms of hepatocellular carcinoma: an update. Arch Toxicol. 2013;87(2):227-247.
    • (2013) Arch Toxicol , vol.87 , Issue.2 , pp. 227-247
    • Aravalli, R.N.1    Cressman, E.N.2    Steer, C.J.3
  • 122
    • 78149386734 scopus 로고    scopus 로고
    • Tumor initiation and progression in hepatocellular carcinoma: Risk factors, classification, and therapeutic targets
    • Severi T, van Malenstein H, Verslype C, van Pelt JF. Tumor initiation and progression in hepatocellular carcinoma: risk factors, classification, and therapeutic targets. Acta Pharmacol Sin. 2010;31(11): 1409-1420.
    • (2010) Acta Pharmacol Sin , vol.31 , Issue.11 , pp. 1409-1420
    • Severi, T.1    van Malenstein, H.2    Verslype, C.3    van Pelt, J.F.4
  • 123
    • 84903575064 scopus 로고    scopus 로고
    • From cirrhosis to hepatocellular carcinoma: New molecular insights on inflammation and cellular senescence
    • Ramakrishna G, Rastogi A, Trehanpati N, Sen B, Khosla R, Sarin SK. From cirrhosis to hepatocellular carcinoma: new molecular insights on inflammation and cellular senescence. Liver Cancer. 2013;2(3-4):367-383.
    • (2013) Liver Cancer , vol.2 , Issue.3-4 , pp. 367-383
    • Ramakrishna, G.1    Rastogi, A.2    Trehanpati, N.3    Sen, B.4    Khosla, R.5    Sarin, S.K.6
  • 124
    • 84869436442 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review
    • White DL, Kanwal F, El-Serag HB. Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review. Clin Gastroenterol Hepatol. 2012;10(12):1342-1359. e2.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , Issue.12 , pp. 1342-1359
    • White, D.L.1    Kanwal, F.2    El-Serag, H.B.3
  • 125
    • 84881027669 scopus 로고    scopus 로고
    • From NAFLD to NASH to fibrosis to HCC: Role of dendritic cell populations in the liver
    • Tacke F, Yoneyama H. From NAFLD to NASH to fibrosis to HCC: role of dendritic cell populations in the liver. Hepatology. 2013;58(2):494-496.
    • (2013) Hepatology , vol.58 , Issue.2 , pp. 494-496
    • Tacke, F.1    Yoneyama, H.2
  • 126
    • 84867208789 scopus 로고    scopus 로고
    • Primary biliary cirrhosis and cancer risk: A systematic review and meta-analysis
    • Liang Y, Yang Z, Zhong R. Primary biliary cirrhosis and cancer risk: a systematic review and meta-analysis. Hepatology. 2012;56(4): 1409-1417.
    • (2012) Hepatology , vol.56 , Issue.4 , pp. 1409-1417
    • Liang, Y.1    Yang, Z.2    Zhong, R.3
  • 127
    • 84888117795 scopus 로고    scopus 로고
    • Role of innate immunity in the development of hepatocellular carcinoma
    • Aravalli RN. Role of innate immunity in the development of hepatocellular carcinoma. World J Gastroenterol. 2013;19(43):7500-7514.
    • (2013) World J Gastroenterol , vol.19 , Issue.43 , pp. 7500-7514
    • Aravalli, R.N.1
  • 128
    • 79952038728 scopus 로고    scopus 로고
    • The tumor microenvironment in hepatocellular carcinoma: Current status and therapeutic targets
    • Yang JD, Nakamura I, Roberts LR. The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets. Semin Cancer Biol. 2011;21(1):35-43.
    • (2011) Semin Cancer Biol , vol.21 , Issue.1 , pp. 35-43
    • Yang, J.D.1    Nakamura, I.2    Roberts, L.R.3
  • 129
    • 4344680938 scopus 로고    scopus 로고
    • Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2′-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase
    • Pinlaor S, Ma N, Hiraku Y, et al. Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2′-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase. Carcinogenesis. 2004;25(8):1535-1542.
    • (2004) Carcinogenesis , vol.25 , Issue.8 , pp. 1535-1542
    • Pinlaor, S.1    Ma, N.2    Hiraku, Y.3
  • 130
    • 77949615892 scopus 로고    scopus 로고
    • Epidemiology of cholangiocarcinoma: An update focusing on risk factors
    • Shin HR, Oh JK, Masuyer E, et al. Epidemiology of cholangiocarcinoma: an update focusing on risk factors. Cancer Sci. 2010;101(3):579-585.
    • (2010) Cancer Sci , vol.101 , Issue.3 , pp. 579-585
    • Shin, H.R.1    Oh, J.K.2    Masuyer, E.3
  • 132
    • 84879589312 scopus 로고    scopus 로고
    • Primary sclerosing cholangitis and cholangiocarcinoma: Pathogenesis and modes of diagnostics
    • Ehlken H, Schramm C. Primary sclerosing cholangitis and cholangiocarcinoma: pathogenesis and modes of diagnostics. Dig Dis. 2013;31(1):118-125.
    • (2013) Dig Dis , vol.31 , Issue.1 , pp. 118-125
    • Ehlken, H.1    Schramm, C.2
  • 133
    • 84878210747 scopus 로고    scopus 로고
    • Cholangiocarcinoma: Risk factors, environmental influences and oncogenesis
    • Al-Bahrani R, Abuetabh Y, Zeitouni N, Sergi C. Cholangiocarcinoma: risk factors, environmental influences and oncogenesis. Ann Clin Lab Sci. 2013;43(2):195-210.
    • (2013) Ann Clin Lab Sci , vol.43 , Issue.2 , pp. 195-210
    • Al-Bahrani, R.1    Abuetabh, Y.2    Zeitouni, N.3    Sergi, C.4
  • 134
    • 84880656950 scopus 로고    scopus 로고
    • Medical risk factors associated with cholangiocarcinoma in taiwan: A population-based case-control study
    • Chang JS, Tsai CR, Chen LT. Medical risk factors associated with cholangiocarcinoma in taiwan: a population-based case-control study. PLoS One. 2013;8(7):e69981.
    • (2013) PLoS One , vol.8 , Issue.7
    • Chang, J.S.1    Tsai, C.R.2    Chen, L.T.3
  • 136
    • 80053301589 scopus 로고    scopus 로고
    • Inflammatory response to liver fluke Opisthorchis viverrini depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans
    • Nair SS, Bommana A, Pakala SB, et al. Inflammatory response to liver fluke Opisthorchis viverrini depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans. Hepatology. 2011;54(4):1388-1397.
    • (2011) Hepatology , vol.54 , Issue.4 , pp. 1388-1397
    • Nair, S.S.1    Bommana, A.2    Pakala, S.B.3
  • 137
    • 2942585417 scopus 로고    scopus 로고
    • The molecular pathogenesis of cholangiocarcinoma
    • Berthiaume EP, Wands J. The molecular pathogenesis of cholangiocarcinoma. Semin Liver Dis. 2004;24(2):127-137.
    • (2004) Semin Liver Dis , vol.24 , Issue.2 , pp. 127-137
    • Berthiaume, E.P.1    Wands, J.2
  • 138
    • 0032714310 scopus 로고    scopus 로고
    • Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line
    • Park J, Tadlock L, Gores GJ, Patel T. Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line. Hepatology. 1999;30(5): 1128-1133.
    • (1999) Hepatology , vol.30 , Issue.5 , pp. 1128-1133
    • Park, J.1    Tadlock, L.2    Gores, G.J.3    Patel, T.4
  • 139
    • 32944479992 scopus 로고    scopus 로고
    • Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells
    • Isomoto H, Kobayashi S, Werneburg NW, et al. Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells. Hepatology. 2005;42(6):1329-1338.
    • (2005) Hepatology , vol.42 , Issue.6 , pp. 1329-1338
    • Isomoto, H.1    Kobayashi, S.2    Werneburg, N.W.3
  • 140
    • 33744959817 scopus 로고    scopus 로고
    • Infection as a risk factor for gallbladder cancer
    • Kumar S, Kumar S, Kumar S. Infection as a risk factor for gallbladder cancer. J Surg Oncol. 2006;93(8):633-639.
    • (2006) J Surg Oncol , vol.93 , Issue.8 , pp. 633-639
    • Kumar, S.1    Kumar, S.2    Kumar, S.3
  • 141
    • 84876520642 scopus 로고    scopus 로고
    • Helicobacter pylori infection, chronic inflammation, and genomic transformations in gastric MALT lymphoma
    • Witkowska M, Smolewski P. Helicobacter pylori infection, chronic inflammation, and genomic transformations in gastric MALT lymphoma. Mediators Inflamm. 2013;2013:523170.
    • (2013) Mediators Inflamm , pp. 523170
    • Witkowska, M.1    Smolewski, P.2
  • 142
    • 46149120101 scopus 로고    scopus 로고
    • Association of t(14;18) translocation with HCV infection in gastrointestinal MALT lymphomas
    • Libra M, Gloghini A, Malaponte G, et al. Association of t(14;18) translocation with HCV infection in gastrointestinal MALT lymphomas. J Hepatol. 2008;49(2):170-174.
    • (2008) J Hepatol , vol.49 , Issue.2 , pp. 170-174
    • Libra, M.1    Gloghini, A.2    Malaponte, G.3
  • 143
    • 9144227738 scopus 로고    scopus 로고
    • Immunoproliferative small intestinal disease associated with Campylobacter jejuni
    • Lecuit M, Abachin E, Martin A, et al. Immunoproliferative small intestinal disease associated with Campylobacter jejuni. N Engl J Med. 2004;350(3):239-248.
    • (2004) N Engl J Med , vol.350 , Issue.3 , pp. 239-248
    • Lecuit, M.1    Abachin, E.2    Martin, A.3
  • 145
    • 84889580237 scopus 로고    scopus 로고
    • Role of Helicobacter pylori virulence factor cytotoxin-associated gene A in gastric mucosa-associated lymphoid tissue lymphoma
    • Wang HP, Zhu YL, Shao W. Role of Helicobacter pylori virulence factor cytotoxin-associated gene A in gastric mucosa-associated lymphoid tissue lymphoma. World J Gastroenterol. 2013;19(45):8219-8226.
    • (2013) World J Gastroenterol , vol.19 , Issue.45 , pp. 8219-8226
    • Wang, H.P.1    Zhu, Y.L.2    Shao, W.3
  • 146
    • 75549090875 scopus 로고    scopus 로고
    • Effects of Helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma
    • Zullo A, Hassan C, Cristofari F, et al. Effects of Helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma. Clin Gastroenterol Hepatol 2010. 2010;8(2):105-110.
    • (2010) Clin Gastroenterol Hepatol 2010 , vol.8 , Issue.2 , pp. 105-110
    • Zullo, A.1    Hassan, C.2    Cristofari, F.3
  • 147
    • 73949159228 scopus 로고    scopus 로고
    • Importance of mucosal healing in ulcerative colitis
    • Lichtenstein GR, Rutgeerts P. Importance of mucosal healing in ulcerative colitis. Inflamm Bowel Dis. 2010;16(2):338-346.
    • (2010) Inflamm Bowel Dis , vol.16 , Issue.2 , pp. 338-346
    • Lichtenstein, G.R.1    Rutgeerts, P.2
  • 148
    • 84866076674 scopus 로고    scopus 로고
    • 5-aminosalicylic acid is not protective against colorectal cancer in inflammatory bowel disease: A meta-analysis of non-referral populations
    • Nguyen GC, Gulamhusein A, Bernstein CN. 5-aminosalicylic acid is not protective against colorectal cancer in inflammatory bowel disease: a meta-analysis of non-referral populations. Am J Gastroenterol. 2012;107(9):1298-1304; quiz 1297, 1305.
    • (2012) Am J Gastroenterol , vol.107 , Issue.9 , pp. 1298-1304
    • Nguyen, G.C.1    Gulamhusein, A.2    Bernstein, C.N.3
  • 149
    • 84896737676 scopus 로고    scopus 로고
    • Impact of non-steroidal anti-inflammatory drugs on gastrointestinal cancers: Current state-of-the science
    • Sahin IH, Hassan MM, Garrett CR. Impact of non-steroidal anti-inflammatory drugs on gastrointestinal cancers: current state-of-the science. Cancer Lett. 2014;345(2):249-257.
    • (2014) Cancer Lett , vol.345 , Issue.2 , pp. 249-257
    • Sahin, I.H.1    Hassan, M.M.2    Garrett, C.R.3
  • 150
    • 84891847947 scopus 로고    scopus 로고
    • Targeting interleukin-6 in inflammatory autoimmune diseases and cancers
    • Yao X, Huang J, Zhong H, et al. Targeting interleukin-6 in inflammatory autoimmune diseases and cancers. Pharmacol Ther. 2014;141(2): 125-139.
    • (2014) Pharmacol Ther , vol.141 , Issue.2 , pp. 125-139
    • Yao, X.1    Huang, J.2    Zhong, H.3
  • 151
    • 84870864817 scopus 로고    scopus 로고
    • Overview of safety of non-biologic and biologic DMARDs
    • Oxford
    • Ruderman EM. Overview of safety of non-biologic and biologic DMARDs. Rheumatology (Oxford). 2012;51 Suppl 6:vi37-vi43.
    • (2012) Rheumatology , vol.51 , Issue.6 , pp. 637-643
    • Ruderman, E.M.1
  • 153
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science. 2006;313(5795):1960-1964.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 154
    • 84877076923 scopus 로고    scopus 로고
    • From the immune contexture to the Immunoscore: The role of prognostic and predictive immune markers in cancer
    • Angell H, Galon J. From the immune contexture to the Immunoscore: the role of prognostic and predictive immune markers in cancer. Curr Opin Immunol. 2013;25(2):261-267.
    • (2013) Curr Opin Immunol , vol.25 , Issue.2 , pp. 261-267
    • Angell, H.1    Galon, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.