From NAFLD to NASH to fibrosis to HCC: Role of dendritic cell populations in the liver

Hepatology

Volumn 58, Issue 2, 2013, Pages 494-496

  Tacke, Frank ^a   Yoneyama, Hiroyuki ^b  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b Stelic Institute of Regenerative Medicine   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P 15095;

ANTIGEN SPECIFICITY; APOPTOSIS; CD4+ T LYMPHOCYTE; CELL FUNCTION; CELL MIGRATION; CELL POPULATION; DENDRITIC CELL; DISEASE MODEL; EDITORIAL; FIBROGENESIS; IMMUNOMODULATION; INFLAMMATION; LIVER CELL CARCINOMA; LIVER FIBROSIS; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; CELL COMMUNICATION; DENDRITIC CELLS; DISEASE PROGRESSION; FATTY LIVER; LIVER; MALE;

EID: 84881027669     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26405     Document Type: Editorial

References (18)

1. Hashimoto D, Miller J, Merad M. Dendritic cell and macrophage heterogeneity in vivo. Immunity 2011;35:323-335.
2. Rahman AH, Aloman C. Dendritic cells and liver fibrosis. Biochim Biophys Acta 2013 Jan 9. doi: 10.1016/j.bbadis.2013.01.005.
3. Bleier JI, Katz SC, Chaudhry UI, Pillarisetty VG, Kingham TP, IIIrd, Shah AB, et al. Biliary obstruction selectively expands and activates liver myeloid dendritic cells. J Immunol 2006;176:7189-7195.
4. Karlmark KR, Weiskirchen R, Zimmermann HW, Gassler N, Ginhoux F, Weber C, et al. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology 2009;50:261-274.
5. Connolly MK, Bedrosian AS, Mallen-St Clair J, Mitchell AP, Ibrahim J, Stroud A, et al. In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha. J Clin Invest 2009;119:3213-3225.
6. Zimmermann HW, Tacke F. Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis. Inflamm Allergy Drug Targets 2011;10:509-536.
7. Henning JR, Graffeo CS, Rehman A, Fallon NC, Zambirinis CP, Ochi A, et al. Dendritic cells limit fibro-inflammatory injury in NASH. Hepatology 2013;;58:589-602.
8. Jiao J, Sastre D, Fiel MI, Lee UE, Ghiassi-Nejad Z, Ginhoux F, et al. Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression. Hepatology 2012;55:244-255.
9. Aloman C, Tacke F. Dendritic cells in liver fibrosis: conductor of the inflammatory orchestra? Hepatology 2010;51:1070-1072.
10. Sander LE, Sackett SD, Dierssen U, Beraza N, Linke RP, Muller M, et al. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J Exp Med 2010;207:1453-1464.
11. Ugel S, Peranzoni E, Desantis G, Chioda M, Walter S, Weinschenk T, et al. Immune tolerance to tumor antigens occurs in a specialized environment of the spleen. Cell Rep 2012;2:628-639.
12. Tittel AP, Heuser C, Ohliger C, Llanto C, Yona S, Hammerling GJ, et al. Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice. Nat Methods 2012;9:385-390.
13. Miyake T, Akbar SM, Yoshida O, Chen S, Hiasa Y, Matsuura B, et al. Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease. J Gastroenterol 2010;45:859-867.
14. Herber DL, Cao W, Nefedova Y, Novitskiy SV, Nagaraj S, Tyurin VA, et al. Lipid accumulation and dendritic cell dysfunction in cancer. Nat Med 2010;16:880-886.
15. Yoneyama H, Matsuno K, Zhang Y, Murai M, Itakura M, Ishikawa S, et al. Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease. J Exp Med 2001;193:35-49.
16. Ochando JC, Chen SH. Myeloid-derived suppressor cells in transplantation and cancer. Immunol Res 2012;54:275-285.
17. Schneider C, Teufel A, Yevsa T, Staib F, Hohmeyer A, Walenda G, et al. Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer. Gut 2012;61:1733-1743.
18. Torres DM, Harrison SA. Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil. Semin Liver Dis 2012;32:30-38.