Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNFα and IL-1α

International Journal of Cancer

Volumn 85, Issue 2, 2000, Pages 182-188

  Torisu, Hitoe ^a   Ono, Mayumi ^a   Kiryu, Hiromaro ^a   Furue, Masutaka ^a   Ohmoto, Yasukazu ^b   Nakayama, Juichiro ^c   Nishioka, Yasuhiko ^d   Sone, Saburo ^d   Kuwano, Michihiko ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^c FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BASIC FIBROBLAST GROWTH FACTOR; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 1ALPHA; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; VASCULOTROPIN;

ARTICLE; CANCER GROWTH; CANCER STAGING; CAPILLARY DENSITY; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; HUMAN CELL; INFLAMMATORY INFILTRATE; LEUKOCYTE COUNT; MACROPHAGE; MACROPHAGE ACTIVATION; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; TUMOR VASCULARIZATION;

EID: 0034650795     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(20000115)85:2<182::AID-IJC6>3.3.CO;2-D     Document Type: Article

References (20)

1. BENNICELLI, J.L. and GUERRY, D., IV, Production of multiple cytokines by cultured human melanomas. Exp. Dermatol., 2, 186-190 (1993).
2. BRÖCKER, E.B., ZWADLO, G., HOLZMANN, B., MACHER, E. and SORG, C., Inflammatory cell infiltrates in human melanoma at different stages of tumor progression. Int. J. Cancer, 41, 562-567 (1988).
3. BUSAM, K.J. and 13 OTHERS, Tumor vascularity is not a prognostic factor for malignant melanoma of the skin. Amer. J. Pathol., 147, 1049-1056 (1995).
4. CLAFFEY, K.P., BROWN, L.F., DEL AGUILA, L.F., TOGNAZZI, K., YEO, K.T., MANSEAU, E.J. and DVORAK, H.F., Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res., 56, 172-181 (1996).
5. DENIJN, M. and RUITER, D.J., The possible role of angiogenesis in the metastatic potential of human melanoma. Clinicopathological aspects. Melanoma Res., 3, 5-14 (1993).
6. DIPIETRO, L. A. and POLVERINI, P.J., Angiogenic macrophages produce the angiogenic inhibitor thrombospondin I. Amer. J. Pathol., 143, 678-684 (1993).
7. DVORAK, H.F., NAGY, J.A., DVORAK, J.T. and DVORAK, A.M., Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Amer. J. Pathol., 133, 95-109 (1988).
8. GRAHAM, C.H., RIVERS, J., KERBEL, R.S., STANKIEWICZ, K.S. and WHITE, W.L., Extent of vascularization as a prognostic indicator in thin (<0.76 mm) malignant melanomas. Amer. J. Pathol., 145, 510-514 (1994).
9. LEEK, R.D., LEWIS, C.E., WHITEHOUSE, R., GREENALL, M., CLARKE, J. and HARRIS, A.L., Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res., 56, 4625-4629 (1996).
10. MARCOVAL, J., MORENO, A., GRAELLS, J., VIDAL, A., ESCRIBA, J.M., GARCIA-RAMIREZ, M. and FABRA, A., Angiogenesis and malignant melanoma. Angiogenesis is related to the development of vertical (tumorigenic) growth phase. J. cutan. Pathol., 24, 212-218 (1997).
11. NISHIE, A., ONO, M., SHONO, T., FUKUSHI, J., OTSUBO, M., ONOUE, H., ITO, Y., INAMURA, T., IKEZAKI, K., FUKUI, M., IWAKI, T., and KUWANO, M., Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas. Clin. Cancer Res., 5, 1107-1113 (1999).
12. NISHIOKA, Y., YANO, S., FUJIKI, F, MUKAIDA, N., MATSUSHIMA, K., TSURUO, T. and SONE, S., Combined therapy of multidrug-resistant human lung cancer with anti-P-glycoprotein antibody and monocyte chemo-attractant protein-1 gene transduction: the possibility of immunological overcoming of multidrug resistance. Int. J. Cancer, 71, 170-177 (1997).
13. NORRBY, K., Interleukin-1 -alpha and de novo mammalian angiogenesis. Microvascular Res., 54, 58-64 (1997).
14. OKAMURA, K., SATO, Y., MATSUDA, T., HAMANAKA, R., ONO, M., KOHNO, K. and KUWANO, M., Endogenous basic-fibroblast-growth-factor-dependent induction of collagenase and interleukin-6 in tumor-necrosis-factor-treated human microvascular endothelial cells. J. biol. Chem., 266, 19162-19165 (1991).
15. ONO, M., TORISU, H., FUKUSHI, J., NISHIK, A. and KUWANO, M., Biological implication of macrophage infiltration in human tumor angiogenesis. Cancer Chemother. Pharmacol., 43 (Suppl.), S69-S71 (1999).
16. POLVERINI, P.J. and LEIBOVICH, S.J., Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages. Lab. Invest., 51, 635-642 (1984).
17. RYUTO, M., ONO, M., IZUMI, H., YOSHIDA, S., WEICH, H.A., KOHNO, K. and KUWANO, M., Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1. J. biol. Chem., 271, 28220-28228 (1996).
18. SHONO, T., ONO, M., IZUMI, H., JIMI, S.I., MATSUSHIMA. K., OKAMOTO, T., KOHNO, K. and KUWANO, M., Involvement of the transcription factor NF-kappa B in tubular morphogenesis of human microvascular endothelial cells by oxidative stress. Mol. cell. Biol., 16, 4231-4239 (1996).
19. WANG, Y. and BECKER, D., Anti-sense targeting of basic fibroblast growth factor and fibroblast-growth-factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth. Nature Med., 3, 887-893 (1997).
20. YOSHIDA, S., ONO, M., SHONO, T., IZUMI, H., ISHIBASHI, T., SUZUKI, H. and KUWANO, M., Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor-necrosis-factor-alpha-dependent angiogenesis. Mol. cell. Biol., 17, 4015-4023 (1997).