Inflammation and cancer: V. Chronic pancreatitis and pancreatic cancer

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 2 50-2, 2004, Pages

  Whitcomb, David C ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

Author keywords

Alcohol; Cystic fibrosis; Hereditary pancreatitis; Inflammation; KRAS; Tropical pancreatitis

Indexed keywords

DNA; TRYPSINOGEN;

ALCOHOLIC PANCREATITIS; CANCER INCIDENCE; CANCER INVASION; CANCER RISK; CHRONIC INFLAMMATION; CHRONIC PANCREATITIS; CLINICAL OBSERVATION; CYSTIC FIBROSIS; DNA REPAIR; GENE MUTATION; GENETIC ASSOCIATION; GENETIC DISORDER; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IDIOPATHIC DISEASE; INFLAMMATION; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PRIORITY JOURNAL; RECURRENT DISEASE; REVIEW; TROPICAL DISEASE;

ADENOCARCINOMA; CHRONIC DISEASE; HUMANS; PANCREATIC NEOPLASMS; PANCREATITIS;

EID: 3242724146     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00115.2004     Document Type: Review

References (26)

1. Augustine P and Ramesh H. Is tropical pancreatitis premalignant? Am J Gastroenterol 87: 1005-1008, 1992.
2. Banke MG, Mulvihill JJ, and Aston CE. Inheritance of pancreatic cancer in pancreatic cancer-prone families. Med Clin North Am 84: 677-690, 2000.
3. Chari ST, Mohan V, Pitchumoni CS, Viswanathan M, Madanagopalan N, and Lowenfels AB. Risk of pancratic carcinoma in tropical calcifying pancreatitits: an epidemicologic study. Pancreas 9: 62-66, 1994.
4. Cohn JA, Friedman KJ, Noone PG, Knowles MR, Silverman LM, and Jowell PS. Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med 339: 653-658, 1998.
5. Eberle MA, Pfutzer R, Pogue-Geile KL, Bronner MP, Crispin D, Kimmey MB, Duerr RH, Kruglyak L, Whitcomb DC, and Brentnall TA. A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34. Am J Hum Genet 70: 1044-1048, 2002.
6. Etemad B and Whitcomb DC. Chronic pancreatitis: diagnosis, classification, and new genetic developments. Gastroenterology 120: 682-707, 2001.
7. Farrow B and Evers BM. Inflammation and the development of pancreatic cancer. Surg Oncol 10: 153-169, 2002.
8. Hahn SA, Greenhalf B, Ellis I, Sina-Frey M, Rieder H, Korte B, Gerdes B, Kress R, Ziegler A, Raeburn JA, Campra D, Grutzmann R, Rehder H, Rothmund M, Schmiegel W, Neoptolemos JP, and Bartsch DK. BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst 95: 214-221, 2003.
9. Hengstler JG, Bauer A, Wolf HK, Bulitta CJ, Tanner B, Oesch F, Gebhard S, and Boettger T. Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer. Anticancer Res 20: 2967-2974, 2000.
10. Howes N, Lerch MM, Greenhalf W, Stocken DD, Ellis I, Simon P, Truninger K, Ammann R, Cavallini G, Charnley R, Uomo G, Delhaye M, Spicak J, Drumm B, Jansen J, Mountford R, Whitcomb DC, and Neoptolemos JP. Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol 2: 252-261, 2004.
11. Hruban RH, Adsay NV, Albores-Saavedra J, Compton C, Garrett ES, Goodman SN, Kern SE, Klimstra DS, Kloppel G, Longnecker DS, Luttges J, and Offerhaus GJ. Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions. Am J Surg Pathol 25: 579-586, 2001.
12. Kinzler KW and Vogelstein B. Landscaping the cancer terrain. Science 280: 1036-1037, 1998.
13. Lowenfels A, Maisonneuve P, DiMagno E, Elitsur Y, Gates L, Perrault J, and Whitcomb D. Hereditary pancreatitis and the risk of pancreatic cancer. J Natl Cancer Inst 89: 442-446, 1997.
14. Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, Dimagno EP, Andren SA, and Domellof L. Pancreatitis and the risk of pancreatic cancer. N Engl J Med 328: 1433-1437, 1993.
15. Lowenfels AB, Maisonneuve P, Whitcomb DC, Lerch MM, and DiMagno EP. Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis. JAMA 286: 169-170, 2001.
16. Malats N, Casals T, Porta M, Guarner L, Estivill X, and Real FX. Cystic fibrosis transmembrane regulator (CFTR) DeltaF508 mutation and 5T allele in patients with chronic pancreatitis and exocrine pancreatic cancer. Gut 48: 70-74, 2001.
17. Mohan V, Premalatha G, and Pitchumoni CS. Tropical chronic pancreatitis: an update. J Clin Gastroenterol 36: 337-346, 2003.
18. Neglia JP, FitzSimmons SC, Malsonneuve P, Schoni MH, Schoni-Affolter F, Corey M, and Lowenfels AB. The risk of cancer among patients with cystic fibrosis. N Engl J Med 332: 494-499, 1995.
19. Pfützer RH, Barmada MM, Brunskil APJ, Finch R, Hart PS, Neoptolemos J, Furey WF, and Whitcomb DC. SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis. Gastroenterology 119: 615-623, 2000.
20. Rossi L, Pfützer RL, Parvin S, Ali L, Sattar S, Azad Kahn AK, Gyr K, and Whitcomb DC. SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh: a preliminary report. Pancreatology 1: 242-245, 2001.
21. Sheldon CD, Hodson ME, Carpenter LM, and Swerdlow AJ. A cohort study of cystic fibrosis and malignancy. Br J Cancer 68: 1025-1028, 1993.
22. Tersmette AC, Petersen GM, Offerhaus GJ, Falatko FC, Brune KA, Goggins M, Rozenblum E, Wilentz RE, Yeo CJ, Cameron JL, Kern SE, and Hruban RH. Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer. Clin Cancer Res 7: 738-744, 2001.
23. Whitcomb DC. Value of genetic testing in management of pancreatitis. Gut. In press.
24. Whitcomb DC, Gorry MC, Preston RA, Furey W, Sossenheimer MJ, Ulrich CD, Martin SP, Gates LK Jr, Amann ST, Toskes PP, Liddle R, McGrath K, Uomo G, Post JC, and Ehrlich GD. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 14: 141-145, 1996.
25. Whitcomb DC and Pogue-Geile K. Pancreatitis as a risk for pancreatic cancer. Gastroenterol Clin North Am 31: 663-678, 2002.
26. Witt H, Luck W, Hennies HC, Classen M, Kage A, Lass U, Landt O, and Becker M. Mutations in the gene encoding the serine protease inhibitor, kazal type 1 are associated with chronic pancreatitis. Nat Genet 25: 213-216, 2000.