Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population

International Journal of Obesity

Volumn 37, Issue 7, 2013, Pages 980-985

  Robiou Du Pont, S ^a,b   Bonnefond, A ^c   Yengo, L ^a,b   Vaillant, E ^a,b   Lobbens, S ^a,b   Durand, E ^a,b   Weill, J ^d   Lantieri, O ^e   Balkau, B ^f,g   Charpentier, G ^h   Marre, M ^c,i   Froguel, P ^a,b,j   Meyre, D ^k  

^a INSTITUT PASTEUR DE LILLE   (France)

^b UNIV LILLE   (France)

^c INSERM   (France)

^d Regional Hospital and University Center   (France)

^e IRSA Institut Inter Régional Pour la Santé   (France)

^f CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^g UNIVERSITÉ PARIS SACLAY   (France)

^h CENTRE HOSPITALIER SUD FRANCILIEN   (France)

ⁱ BICHAT HOSPITAL   (France)

^j HAMMERSMITH HOSPITAL   (United Kingdom)

^k MCMASTER UNIVERSITY   (Canada)

more..

Author keywords

Insulin resistance; Pancreatic function; SNP; Type 2 diabetes

Indexed keywords

INSULIN;

ADULT; AGED; ALLELE; ARTICLE; CASE CONTROL STUDY; CELL FUNCTION; CONTROLLED STUDY; FEMALE; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PANCREAS ISLET BETA CELL; PHENOTYPE; POPULATION RESEARCH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; BODY MASS INDEX; CYCLIN-DEPENDENT KINASE 5; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FRANCE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HOMEOSTASIS; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; OBESITY; PHENOTYPE; PHOSPHORIC DIESTER HYDROLASES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; PYROPHOSPHATASES; RISK FACTORS;

EID: 84880255967     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2012.175     Document Type: Article

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