Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

Nature Genetics

Volumn 44, Issue 3, 2012, Pages 297-301

  Bonnefond, Amélie ^a,b   Clément, Nathalie ^c,d   Fawcett, Katherine ^e   Yengo, Loic ^a,b   Vaillant, Emmanuel ^a,b   Guillaume, Jean Luc ^c,d   Dechaume, Aurélie ^b,c   Payne, Felicity ^e   Roussel, Ronan ^f,g   Czernichow, Sébastien ^h,i   Hercberg, Serge ^j,k   Hadjadj, Samy ^g,l   Balkau, Beverley ^m,n   Marre, Michel ^f,g   Lantieri, Olivier ^o   Langenberg, Claudia ^p   Bouatia Naji, Nabila ^a,b   Charpentier, Guillaume ^q   Vaxillaire, Martine ^a,b,x   Rocheleau, Ghislain ^r,s   Wareham, Nicholas J ^p   Sladek, Robert ^t,u   McCarthy, Mark I ^v,w   Dina, Christian ^y,z   Barroso, Ins ^e,aa   Jockers, Ralf ^c,d   Froguel, Philippe ^a,b,ab   more..

^a CNRS   (France)

^b UNIV LILLE   (France)

^c INSTITUT COCHIN   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^f BICHAT HOSPITAL   (France)

^g INSERM   (France)

^h HÔPITAL AMBROISE PARÉ   (France)

ⁱ LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^j University of Versailles Saint Quentin ^*  (France)

^k AVICENNE HOSPITAL   (France)

^l POITIERS UNIVERSITY HOSPITAL   (France)

^m CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

ⁿ UNIVERSITÉ PARIS SACLAY   (France)

^o IRSA Institut Inter Régional Pour la Santé   (France)

^p UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^q CENTRE HOSPITALIER SUD FRANCILIEN   (France)

^r CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^s Prognomix   (Canada)

^t MCGILL UNIVERSITY   (Canada)

^u Genome Quebec Innovation Centre   (Canada)

^v UNIVERSITY OF OXFORD   (United Kingdom)

^w UNIVERSITY OF OXFORD   (United Kingdom)

^x L INSTITUT DU THORAX   (France)

^y CNRS Equipe de Recherche Labellisée 3147   (France)

^z UNIVERSITÉ DE NANTES   (France)

^aa ADDENBROOKE S HOSPITAL   (United Kingdom)

^ab IMPERIAL COLLEGE LONDON   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN; MELATONIN 2 RECEPTOR;

ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; EXON; GENE; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; LOSS OF FUNCTION MUTATION; MTNR1B GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BINDING; RISK;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BASE SEQUENCE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; GENE FREQUENCY; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LOGISTIC MODELS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ODDS RATIO; RECEPTOR, MELATONIN, MT2; SEQUENCE ANALYSIS, DNA;

EID: 84857654651     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.1053     Document Type: Article

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