Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity

Diabetes

Volumn 61, Issue 2, 2012, Pages 383-390

  Creemers, John W M ^a   Choquet, Hélène ^b   Stijnen, Pieter ^a   Vatin, Vincent ^b   Pigeyre, Marie ^b   Beckers, Sigri ^c   Meulemans, Sandra ^a   Than, Manuel E ^d   Yengo, Loïc ^b   Tauber, Maithé ^e   Balkau, Beverley ^f,g   Elliott, Paul ^h   Jarvelin, Marjo Riitta ^h,i   Van Hul, Wim ^c   Van Gaal, Luc ^j   Horber, Fritz ^k   Pattou, François ^b   Froguel, Philippe ^b,h   Meyre, David ^b,l  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIV LILLE   (France)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d FRITZ LIPMANN INSTITUTE   (Germany)

^e TOULOUSE UNIVERSITY HOSPITAL   (France)

^f CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^g UNIVERSITÉ PARIS SACLAY   (France)

^h IMPERIAL COLLEGE LONDON   (United Kingdom)

ⁱ UNIVERSITY OF OULU   (Finland)

^j ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^k Department of Surgery and Internal Medicine   (Switzerland)

^l MCMASTER UNIVERSITY   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FURIN; PROHORMONE CONVERTASE 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BINDING SITE; CHILD; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; EUROPE; EXON; FEMALE; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC RISK; GENETIC VARIABILITY; HETEROZYGOSITY; HIGH RISK PATIENT; HUMAN; HUMAN CELL; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; OBESITY; PARTIAL PROHORMONE CONVERTASE 1 DEFICIENCY; PCSK1 GENE; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; WILD TYPE;

ADULT; FEMALE; GENOTYPE; GLYCOSYLATION; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; OBESITY; PROPROTEIN CONVERTASE 1;

EID: 84856523505     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0305     Document Type: Article

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