-
1
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, et al. (2008) SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 40: 1098-1102.
-
(2008)
Nat Genet
, vol.40
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
Hara, K.4
Horikoshi, M.5
-
2
-
-
50449085998
-
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
-
Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, et al. (2008) Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 40: 1092-1097.
-
(2008)
Nat Genet
, vol.40
, pp. 1092-1097
-
-
Yasuda, K.1
Miyake, K.2
Horikawa, Y.3
Hara, K.4
Osawa, H.5
-
3
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445: 881-885.
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
-
4
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316: 1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
-
5
-
-
34249885875
-
A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, et al. (2007) A genomewide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316: 1341-1345.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
-
6
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, et al. (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316: 1336-1341.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
-
7
-
-
42349106044
-
Metaanalysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, et al. (2008) Metaanalysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 40: 638-645.
-
(2008)
Nat Genet
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
Marchini, J.L.5
-
8
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, et al. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38: 320-323.
-
(2006)
Nat Genet
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
-
9
-
-
0033624575
-
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80.
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
-
10
-
-
0037317981
-
Largescale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, et al. (2003) Largescale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes 52: 568-572.
-
(2003)
Diabetes
, vol.52
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
-
11
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, et al. (2007) A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 39: 770-775.
-
(2007)
Nat Genet
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
-
12
-
-
34547536393
-
Common variants in WFS1 confer risk of type 2 diabetes
-
Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, et al. (2007) Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet 39: 951-953.
-
(2007)
Nat Genet
, vol.39
, pp. 951-953
-
-
Sandhu, M.S.1
Weedon, M.N.2
Fawcett, K.A.3
Wasson, J.4
Debenham, S.L.5
-
13
-
-
34547510624
-
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
-
Gudmundsson J, Sulem P, Steinthorsdottir V, Bergthorsson JT, Thorleifsson G, et al. (2007) Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet 39: 977-983.
-
(2007)
Nat Genet
, vol.39
, pp. 977-983
-
-
Gudmundsson, J.1
Sulem, P.2
Steinthorsdottir, V.3
Bergthorsson, J.T.4
Thorleifsson, G.5
-
14
-
-
65249114674
-
Diabetes prevalence and body mass index differ by ethnicity: The Multiethnic Cohort
-
Maskarinec G, Grandinetti A, Matsuura G, Sharma S, Mau M, et al. (2009) Diabetes prevalence and body mass index differ by ethnicity: the Multiethnic Cohort. Ethn Dis 19: 49-55.
-
(2009)
Ethn Dis
, vol.19
, pp. 49-55
-
-
Maskarinec, G.1
Grandinetti, A.2
Matsuura, G.3
Sharma, S.4
Mau, M.5
-
15
-
-
68049136006
-
Diabetes incidence based on linkages with health plans: The multiethnic cohort
-
Maskarinec G, Erber E, Grandinetti A, Verheus M, Oum R, et al. (2009) Diabetes incidence based on linkages with health plans: the multiethnic cohort. Diabetes 58: 1732-1738.
-
(2009)
Diabetes
, vol.58
, pp. 1732-1738
-
-
Maskarinec, G.1
Erber, E.2
Grandinetti, A.3
Verheus, M.4
Oum, R.5
-
16
-
-
33749003979
-
Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men
-
Freedman ML, Haiman CA, Patterson N, McDonald GJ, Tandon A, et al. (2006) Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci U S A 103: 14068-14073.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14068-14073
-
-
Freedman, M.L.1
Haiman, C.A.2
Patterson, N.3
McDonald, G.J.4
Tandon, A.5
-
17
-
-
34247482327
-
Multiple regions within 8q24 independently affect risk for prostate cancer
-
Haiman CA, Patterson N, Freedman ML, Myers SR, Pike MC, et al. (2007) Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet 39: 638-644.
-
(2007)
Nat Genet
, vol.39
, pp. 638-644
-
-
Haiman, C.A.1
Patterson, N.2
Freedman, M.L.3
Myers, S.R.4
Pike, M.C.5
-
18
-
-
52949092735
-
MYH9 is associated with nondiabetic end-stage renal disease in African Americans
-
Kao WH, Klag MJ, Meoni LA, Reich D, Berthier-Schaad Y, et al. (2008) MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet 40: 1185-1192.
-
(2008)
Nat Genet
, vol.40
, pp. 1185-1192
-
-
Kao, W.H.1
Klag, M.J.2
Meoni, L.A.3
Reich, D.4
Berthier-Schaad, Y.5
-
19
-
-
65949107547
-
Common genetic variation and human traits
-
Goldstein DB (2009) Common genetic variation and human traits. N Engl J Med 360: 1696-1698.
-
(2009)
N Engl J Med
, vol.360
, pp. 1696-1698
-
-
Goldstein, D.B.1
-
20
-
-
77249134594
-
Rare Variants Create Synthetic Genome-Wide Associations
-
doi:10.1371/journal.pbio.1000294
-
Dickson SP, Wang K, Krantz I, Hakonarson H, Goldstein DB (2010) Rare Variants Create Synthetic Genome-Wide Associations. PLoS Biol 8: e1000294. doi:10.1371/journal.pbio.1000294.
-
(2010)
PLoS Biol
, vol.8
-
-
Dickson, S.P.1
Wang, K.2
Krantz, I.3
Hakonarson, H.4
Goldstein, D.B.5
-
21
-
-
77951974619
-
Interpretation of association signals and identification of causal variants from genome-wide association studies
-
Wang K, Dickson SP, Stolle CA, Krantz ID, Goldstein DB, et al. (2010) Interpretation of association signals and identification of causal variants from genome-wide association studies. Am J Hum Genet 86: 730-742.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 730-742
-
-
Wang, K.1
Dickson, S.P.2
Stolle, C.A.3
Krantz, I.D.4
Goldstein, D.B.5
-
22
-
-
70349640785
-
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
-
Jonsson A, Isomaa B, Tuomi T, Taneera J, Salehi A, et al. (2009) A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes 58: 2409-2413.
-
(2009)
Diabetes
, vol.58
, pp. 2409-2413
-
-
Jonsson, A.1
Isomaa, B.2
Tuomi, T.3
Taneera, J.4
Salehi, A.5
-
23
-
-
67650663161
-
Strong association of socioeconomic status with genetic ancestry in Latinos: Implications for admixture studies of type 2 diabetes
-
Florez JC, Price AL, Campbell D, Riba L, Parra MV, et al. (2009) Strong association of socioeconomic status with genetic ancestry in Latinos: implications for admixture studies of type 2 diabetes. Diabetologia 52: 1528-1536.
-
(2009)
Diabetologia
, vol.52
, pp. 1528-1536
-
-
Florez, J.C.1
Price, A.L.2
Campbell, D.3
Riba, L.4
Parra, M.V.5
-
24
-
-
63249118012
-
Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening
-
Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, et al. (2009) Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. Diabetes 58: 493-498.
-
(2009)
Diabetes
, vol.58
, pp. 493-498
-
-
Tabara, Y.1
Osawa, H.2
Kawamoto, R.3
Onuma, H.4
Shimizu, I.5
-
25
-
-
67650248695
-
Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
-
Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, et al. (2009) Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes 58: 1690-1699.
-
(2009)
Diabetes
, vol.58
, pp. 1690-1699
-
-
Takeuchi, F.1
Serizawa, M.2
Yamamoto, K.3
Fujisawa, T.4
Nakashima, E.5
-
26
-
-
57349191471
-
Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
-
Lee YH, Kang ES, Kim SH, Han SJ, Kim CH, et al. (2008) Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population. J Hum Genet 53: 991-998.
-
(2008)
J Hum Genet
, vol.53
, pp. 991-998
-
-
Lee, Y.H.1
Kang, E.S.2
Kim, S.H.3
Han, S.J.4
Kim, C.H.5
-
27
-
-
75149150236
-
Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore
-
Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, et al. (2010) Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore. J Clin Endocrinol Metab 95: 390-397.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 390-397
-
-
Tan, J.T.1
Ng, D.P.2
Nurbaya, S.3
Ye, S.4
Lim, X.L.5
-
28
-
-
56349170898
-
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
-
Wu Y, Li H, Loos RJ, Yu Z, Ye X, et al. (2008) Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Diabetes 57: 2834-2842.
-
(2008)
Diabetes
, vol.57
, pp. 2834-2842
-
-
Wu, Y.1
Li, H.2
Loos, R.J.3
Yu, Z.4
Ye, X.5
-
29
-
-
18844474648
-
A multiethnic cohort in Hawaii and Los Angeles: Baseline characteristics
-
Kolonel LN, Henderson BE, Hankin JH, Nomura AM, Wilkens LR, et al. (2000) A multiethnic cohort in Hawaii and Los Angeles: baseline characteristics. Am J Epidemiol 151: 346-357.
-
(2000)
Am J Epidemiol
, vol.151
, pp. 346-357
-
-
Kolonel, L.N.1
Henderson, B.E.2
Hankin, J.H.3
Nomura, A.M.4
Wilkens, L.R.5
-
30
-
-
0027291689
-
Allelic discrimination by nick-translation PCR with fluorogenic probes
-
Lee LG, Connell CR, Bloch W (1993) Allelic discrimination by nick-translation PCR with fluorogenic probes. Nucleic Acids Res 21: 3761-3766.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 3761-3766
-
-
Lee, L.G.1
Connell, C.R.2
Bloch, W.3
-
31
-
-
67149130298
-
Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X
-
doi:10.1371/journal.pgen.1000490
-
Cheng CY, Kao WH, Patterson N, Tandon A, Haiman CA, et al. (2009) Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X. PLoS Genet 5: e1000490. doi:10.1371/journal.pgen.1000490.
-
(2009)
PLoS Genet
, vol.5
-
-
Cheng, C.Y.1
Kao, W.H.2
Patterson, N.3
Tandon, A.4
Haiman, C.A.5
-
32
-
-
37349125527
-
A high-density admixture scan in 1,670 African Americans with hypertension
-
doi:10.1371/journal.pgen.0030196
-
Deo RC, Patterson N, Tandon A, McDonald GJ, Haiman CA, et al. (2007) A high-density admixture scan in 1,670 African Americans with hypertension. PLoS Genet 3: e196. doi:10.1371/journal.pgen.0030196.
-
(2007)
PLoS Genet
, vol.3
-
-
Deo, R.C.1
Patterson, N.2
Tandon, A.3
McDonald, G.J.4
Haiman, C.A.5
|