Prion-like properties of Tau protein: The importance of extracellular Tau as a therapeutic target

Journal of Biological Chemistry

Volumn 289, Issue 29, 2014, Pages 19855-19861

  Holmes, Brandon B ^a   Diamond, Marc I ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; PROTEINS;

CONFORMATIONAL CHANGE; EXTRACELLULAR; EXTRACELLULAR PROTEINS; PRECLINICAL STUDIES; PROTEIN AGGREGATES; SMALL MOLECULES; THERAPEUTIC ANTIBODIES; THERAPEUTIC TARGETS;

AGGREGATES;

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; EPIMERASE; MONOCLONAL ANTIBODY; PRION PROTEIN; PROTEOHEPARAN SULFATE; SULFOTRANSFERASE; TAU PROTEIN;

AMYLOIDOSIS; CELL SURFACE; CREUTZFELDT JAKOB DISEASE; DEGENERATIVE DISEASE; DISEASE COURSE; ENDOCYTOSIS; ENTORHINAL CORTEX; EUKARYOTIC CELL; EXOSOME; GENE EXPRESSION; HUMAN; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PINOCYTOSIS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SHORT SURVEY;

AGGREGATE PROPAGATION; ALPHA-SYNUCLEIN (A-SYNUCLEIN); CHEMOPREVENTION; NEURODEGENERATIVE DISEASE; PRION; TAU PROTEIN (TAU); THERAPY;

ALPHA-SYNUCLEIN; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL MEMBRANE; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; PRIONS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; TAU PROTEINS; TAUOPATHIES; VACCINES;

EID: 84904488776     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R114.549295     Document Type: Short Survey

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