Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

Neuron

Volumn 72, Issue 1, 2011, Pages 57-71

  Volpicelli Daley, Laura A ^a   Luk, Kelvin C ^a   Patel, Tapan P ^b   Tanik, Selcuk A ^a   Riddle, Dawn M ^a   Stieber, Anna ^a   Meaney, David F ^b   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; MUTANT PROTEIN; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL INCLUSION; CONTROLLED STUDY; DIFFUSE LEWY BODY DISEASE; DISEASE COURSE; ENDOCYTOSIS; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL NECROSIS; NERVE GROWTH; NEURITE; NEUROFILAMENT; NEUROLOGIC DISEASE; NONHUMAN; PATHOGENESIS; PERIKARYON; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SYNAPTIC DYSFUNCTION; WILD TYPE;

ALPHA-SYNUCLEIN; ANIMALS; AXONAL TRANSPORT; CELL DEATH; ENDOCYTOSIS; HIPPOCAMPUS; HUMANS; LEWY BODIES; MICE; MICE, INBRED C57BL; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURITES; NEURONS; PRIMARY CELL CULTURE; SYNAPSES; VOLTAGE-SENSITIVE DYE IMAGING;

EID: 80053613574     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2011.08.033     Document Type: Article

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