MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 27, 2014, Pages

  Li, Chaoran ^a   Jiang, Shan ^a,c   Liu, Si Qi ^a   Lykken, Erik ^a   Zhao, Lin Tao ^b   Sevilla, Jose ^a   Zhu, Bo ^b   Li, Qi Jing ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c SHENZHEN UNIVERSITY   (China)

Author keywords

CNS2 acetylation; Epigenetic regulation; Immune homeostasis; Regulatory T cell stability

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; HISTONE H3; METHYL CPG BINDING PROTEIN 2; TRANSCRIPTION FACTOR FOXP3;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; COLITIS; CONTROLLED STUDY; EPIGENETICS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENE; GENE LOCUS; GENE SILENCING; HISTONE ACETYLATION; INFLAMMATION; INFLAMMATORY BOWEL DISEASE; LYMPHOCYTE FUNCTION; METHYL CPG BINDING GENE 2; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; STABLE EXPRESSION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE RESILIENCE; TRANSCRIPTION FACTOR FOXP3 GENE; YOUNG ADULT;

CNS2 ACETYLATION; EPIGENETIC REGULATION; IMMUNE HOMEOSTASIS; REGULATORY T-CELL STABILITY;

ACETYLATION; ANIMALS; COLITIS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTORS; GENE SILENCING; HISTONES; LYMPHOCYTE ACTIVATION; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, TRANSGENIC; T-LYMPHOCYTES, REGULATORY;

EID: 84903950937     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1401505111     Document Type: Article

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