Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

Journal of Experimental Medicine

Volumn 205, Issue 9, 2008, Pages 1983-1991

  Zhou, Xuyu ^a   Jeker, Lukas T ^a   Fife, Brian T ^a   Zhu, Shirley ^a   Anderson, Mark S ^a,b   McManus, Michael T ^a,b   Bluestone, Jeffrey A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DICER; GAMMA INTERFERON; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 7 RECEPTOR; MICRORNA; NEUROPILIN 1; TRANSCRIPTION FACTOR FOXP3;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; BACTERIAL ARTIFICIAL CHROMOSOME; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; GENE DISRUPTION; GENETIC TRANSCRIPTION; HELPER CELL; HOMEOSTASIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; THYMUS;

ANIMALS; AUTOIMMUNITY; CELL DIFFERENTIATION; CELL SEPARATION; CHROMOSOMES, ARTIFICIAL, BACTERIAL; DEAD-BOX RNA HELICASES; ENDORIBONUCLEASES; FLOW CYTOMETRY; IMMUNE SYSTEM; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICRORNAS; PHENOTYPE; T-LYMPHOCYTES, REGULATORY;

EID: 51049120236     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20080707     Document Type: Article

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