메뉴 건너뛰기




Volumn 60, Issue 4, 2009, Pages 1076-1084

Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus

(23)  Webb, Ryan a   Wren, Jonathan D b   Jeffries, Matlock a   Kelly, Jennifer A b   Kaufman, Kenneth M a   Tang, Yuhong c   Frank, Mark Barton b   Merrill, Joan a   Kimberly, Robert P d   Edberg, Jeffrey C d   Ramsey Goldman, Rosalind e   Petri, Michelle f   Reveille, John D g   Alarcón, Graciela S d   Vilá, Luis M h   Alarcón Riquelme, Marta E i   James, Judith A a   Vyse, Timothy J j   Moser, Kathy L b   Gaffney, Patrick M b   more..


Author keywords

[No Author keywords available]

Indexed keywords

METHYL CPG BINDING PROTEIN 2;

EID: 65249109807     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24360     Document Type: Article
Times cited : (81)

References (42)
  • 1
    • 4344625903 scopus 로고    scopus 로고
    • Antinuclear autoantibodies in systemic lupus erythematosus
    • Sawalha AH, Harley JB. Antinuclear autoantibodies in systemic lupus erythematosus. Curr Opin Rheumatol 2004;16:534-40.
    • (2004) Curr Opin Rheumatol , vol.16 , pp. 534-540
    • Sawalha, A.H.1    Harley, J.B.2
  • 2
    • 0026741293 scopus 로고
    • Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus
    • Richardson BC, Strahler JR, Pivirotto TS, Quddus J, Bayliss GE, Gross LA, et al. Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus. Arthritis Rheum 1992;35: 647-62.
    • (1992) Arthritis Rheum , vol.35 , pp. 647-662
    • Richardson, B.C.1    Strahler, J.R.2    Pivirotto, T.S.3    Quddus, J.4    Bayliss, G.E.5    Gross, L.A.6
  • 3
    • 14844348806 scopus 로고    scopus 로고
    • DNA methylation in the pathogenesis of systemic lupus erythematosus
    • Sawalha AH, Richardson BC. DNA methylation in the pathogenesis of systemic lupus erythematosus. Curr Pharmacogenomics 2005;3:73-8.
    • (2005) Curr Pharmacogenomics , vol.3 , pp. 73-78
    • Sawalha, A.H.1    Richardson, B.C.2
  • 4
    • 38449104652 scopus 로고    scopus 로고
    • Impaired T cell protein kinase CS activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus
    • Gorelik G, Fang JY, Wu A, Sawalha AH, Richardson B. Impaired T cell protein kinase CS activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus. J Immunol 2007;179:5553-63.
    • (2007) J Immunol , vol.179 , pp. 5553-5563
    • Gorelik, G.1    Fang, J.Y.2    Wu, A.3    Sawalha, A.H.4    Richardson, B.5
  • 5
    • 2642556447 scopus 로고    scopus 로고
    • Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors
    • Oelke K, Lu Q, Richardson D, Wu A, Deng C, Hanash S, et al. Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. Arthritis Rheum 2004;50:1850-60.
    • (2004) Arthritis Rheum , vol.50 , pp. 1850-1860
    • Oelke, K.1    Lu, Q.2    Richardson, D.3    Wu, A.4    Deng, C.5    Hanash, S.6
  • 6
    • 0028986033 scopus 로고
    • Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo
    • Yung RL, Quddus J, Chrisp CE, Johnson KJ, Richardson BC. Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo. J Immunol 1995;154:3025-35.
    • (1995) J Immunol , vol.154 , pp. 3025-3035
    • Yung, R.L.1    Quddus, J.2    Chrisp, C.E.3    Johnson, K.J.4    Richardson, B.C.5
  • 10
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, et al. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 2008;320:1224-9.
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5    Qin, J.6
  • 11
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]
    • for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology
    • Hochberg MC, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
    • (1997) Arthritis Rheum , vol.40 , pp. 1725
    • Hochberg, M.C.1
  • 12
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Mailer J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21: 263-5.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Mailer, J.3    Daly, M.J.4
  • 14
    • 85142197793 scopus 로고    scopus 로고
    • Dozmorov I, Centola M. An associative analysis of gene expression array data. Bioinformatics 2003;19:204-ll.
    • Dozmorov I, Centola M. An associative analysis of gene expression array data. Bioinformatics 2003;19:204-ll.
  • 15
    • 1042269463 scopus 로고    scopus 로고
    • Shared relationship analysis: Ranking set cohesion and commonalities within a literature-derived relationship network
    • Wren JD, Garner HR. Shared relationship analysis: ranking set cohesion and commonalities within a literature-derived relationship network. Bioinformatics 2004;20:191-8.
    • (2004) Bioinformatics , vol.20 , pp. 191-198
    • Wren, J.D.1    Garner, H.R.2
  • 17
    • 12144287057 scopus 로고    scopus 로고
    • Mnatzakanian GN, Lohi H, Munteanu I, Alfred SE, Yamada T, MacLeod PJ, et al. A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome [published erratum appears in Nat Genet 2004;36:540]. Nat Genet 2004;36:339-41.
    • Mnatzakanian GN, Lohi H, Munteanu I, Alfred SE, Yamada T, MacLeod PJ, et al. A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome [published erratum appears in Nat Genet 2004;36:540]. Nat Genet 2004;36:339-41.
  • 18
    • 2542481314 scopus 로고    scopus 로고
    • The major form of MeCP2 has a novel N-terminus generated by alternative splicing
    • Kriaucionis S, Bird A. The major form of MeCP2 has a novel N-terminus generated by alternative splicing. Nucleic Acids Res 2004;32:1818-23.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1818-1823
    • Kriaucionis, S.1    Bird, A.2
  • 19
  • 21
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 1998;393:386-9.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6
  • 22
    • 38449116161 scopus 로고    scopus 로고
    • Demethylation of CD40LG on the inactive X in T cells from women with lupus
    • Lu Q, Wu A, Tesmer L, Ray D, Yousif N, Richardson B. Demethylation of CD40LG on the inactive X in T cells from women with lupus. J Immunol 2007;179:6352-8.
    • (2007) J Immunol , vol.179 , pp. 6352-6358
    • Lu, Q.1    Wu, A.2    Tesmer, L.3    Ray, D.4    Yousif, N.5    Richardson, B.6
  • 23
    • 33745625865 scopus 로고    scopus 로고
    • Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients
    • Tan FK, Zhou X, Mayes MD, Gourh P, Guo X, Marcum C, et al. Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients. Rheumatology (Oxford) 2006;45:694-702.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 694-702
    • Tan, F.K.1    Zhou, X.2    Mayes, M.D.3    Gourh, P.4    Guo, X.5    Marcum, C.6
  • 24
    • 18644384042 scopus 로고    scopus 로고
    • Activation of the interferon-α pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease
    • Kirou KA, Lee C, George S, Louca K, Peterson MG, Crow MK. Activation of the interferon-α pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. Arthritis Rheum 2005;52:1491-503.
    • (2005) Arthritis Rheum , vol.52 , pp. 1491-1503
    • Kirou, K.A.1    Lee, C.2    George, S.3    Louca, K.4    Peterson, M.G.5    Crow, M.K.6
  • 25
    • 42649137264 scopus 로고    scopus 로고
    • Epigenetics and T-cell immunity
    • Sawalha AH. Epigenetics and T-cell immunity. Autoimmunity 2008;41:245-52.
    • (2008) Autoimmunity , vol.41 , pp. 245-252
    • Sawalha, A.H.1
  • 26
    • 0033681250 scopus 로고    scopus 로고
    • Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter
    • Agalioti T, Lomvardas S, Parekh B, Yie J, Maniatis T, Thanos D. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter. Cell 2000;103:667-78.
    • (2000) Cell , vol.103 , pp. 667-678
    • Agalioti, T.1    Lomvardas, S.2    Parekh, B.3    Yie, J.4    Maniatis, T.5    Thanos, D.6
  • 27
    • 44849087740 scopus 로고    scopus 로고
    • Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients
    • Sawalha AH, Jeffries M, Webb R, Lu Q, Gorelik G, Ray D, et al. Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes Immun 2008;9:368-78.
    • (2008) Genes Immun , vol.9 , pp. 368-378
    • Sawalha, A.H.1    Jeffries, M.2    Webb, R.3    Lu, Q.4    Gorelik, G.5    Ray, D.6
  • 28
    • 13244268327 scopus 로고    scopus 로고
    • Extending the mutual information measure to rank inferred literature relationships
    • Wren JD. Extending the mutual information measure to rank inferred literature relationships. BMC Bioinformatics 2004;5:145.
    • (2004) BMC Bioinformatics , vol.5 , pp. 145
    • Wren, J.D.1
  • 29
    • 1342330525 scopus 로고    scopus 로고
    • Knowledge discovery by automated identification and ranking of implicit relationships
    • Wren JD, Bekeredjian R, Stewart JA, Shohet RV, Garner HR. Knowledge discovery by automated identification and ranking of implicit relationships. Bioinformatics 2004;20:389-98.
    • (2004) Bioinformatics , vol.20 , pp. 389-398
    • Wren, J.D.1    Bekeredjian, R.2    Stewart, J.A.3    Shohet, R.V.4    Garner, H.R.5
  • 30
    • 33747857815 scopus 로고    scopus 로고
    • Dual role of TMS1/ASC in death receptor signaling
    • Parsons MJ, Vertino PM. Dual role of TMS1/ASC in death receptor signaling. Oncogene 2006;25:6948-58.
    • (2006) Oncogene , vol.25 , pp. 6948-6958
    • Parsons, M.J.1    Vertino, P.M.2
  • 31
    • 40449097257 scopus 로고    scopus 로고
    • The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
    • Muruve DA, Petrilli V, Zaiss AK, White LR, Clark SA, Ross PJ, et al. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 2008;452: 103-7.
    • (2008) Nature , vol.452 , pp. 103-107
    • Muruve, D.A.1    Petrilli, V.2    Zaiss, A.K.3    White, L.R.4    Clark, S.A.5    Ross, P.J.6
  • 32
    • 23244439221 scopus 로고    scopus 로고
    • Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene
    • Chen WD, Han ZJ, Skoletsky J, Olson J, Sah J, Myeroff L, et al. Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene. J Natl Cancer Inst 2005;97: 1124-32.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1124-1132
    • Chen, W.D.1    Han, Z.J.2    Skoletsky, J.3    Olson, J.4    Sah, J.5    Myeroff, L.6
  • 33
    • 38849109516 scopus 로고    scopus 로고
    • Aberrant methylation in promoter regions of cyclin-dependent kinase inhibitor genes in adenoid cystic carcinoma of the salivary gland
    • Daa T, Kashima K, Kondo Y, Yada N, Suzuki M, Yokoyama S. Aberrant methylation in promoter regions of cyclin-dependent kinase inhibitor genes in adenoid cystic carcinoma of the salivary gland. APMIS 2008;116:21-6.
    • (2008) APMIS , vol.116 , pp. 21-26
    • Daa, T.1    Kashima, K.2    Kondo, Y.3    Yada, N.4    Suzuki, M.5    Yokoyama, S.6
  • 34
    • 0037097819 scopus 로고    scopus 로고
    • Effect of DNA methylation and chromatin structure on ITGAL expression
    • Lu Q, Ray D, Gutsch D, Richardson B. Effect of DNA methylation and chromatin structure on ITGAL expression. Blood 2002;99:4503-8.
    • (2002) Blood , vol.99 , pp. 4503-4508
    • Lu, Q.1    Ray, D.2    Gutsch, D.3    Richardson, B.4
  • 35
    • 0036095885 scopus 로고    scopus 로고
    • Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
    • Lu Q, Kaplan M, Ray D, Ray D, Zacharek S, Gutsch D, et al. Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus. Arthritis Rheum 2002;46:1282-91.
    • (2002) Arthritis Rheum , vol.46 , pp. 1282-1291
    • Lu, Q.1    Kaplan, M.2    Ray, D.3    Ray, D.4    Zacharek, S.5    Gutsch, D.6
  • 36
    • 36248992253 scopus 로고    scopus 로고
    • Epigenetic down-regulation of ARF expression is a selection step in immortalization of human fibroblasts by c-Myc
    • Benanti JA, Wang ML, Myers HE, Robinson KL, Grandori C, Galloway DA. Epigenetic down-regulation of ARF expression is a selection step in immortalization of human fibroblasts by c-Myc. Mol Cancer Res 2007;5:1181-9.
    • (2007) Mol Cancer Res , vol.5 , pp. 1181-1189
    • Benanti, J.A.1    Wang, M.L.2    Myers, H.E.3    Robinson, K.L.4    Grandori, C.5    Galloway, D.A.6
  • 38
    • 0022636168 scopus 로고
    • Increased proto-oncogene expression in peripheral blood lymphocytes from patients with systemic lupus erythematosus and other autoimmune diseases
    • Boumpas DT, Tsokos GC, Mann DL, Eleftheriades EG, Harris CC, Mark GE. Increased proto-oncogene expression in peripheral blood lymphocytes from patients with systemic lupus erythematosus and other autoimmune diseases. Arthritis Rheum 1986;29: 755-60.
    • (1986) Arthritis Rheum , vol.29 , pp. 755-760
    • Boumpas, D.T.1    Tsokos, G.C.2    Mann, D.L.3    Eleftheriades, E.G.4    Harris, C.C.5    Mark, G.E.6
  • 39
    • 0028344936 scopus 로고
    • Expression of c-myc, c-myb, and c-sis in fibroblasts from affected and unaffected skin of patients with systemic sclerosis
    • Feghali CA, Boulware DW, Ferriss JA, Levy LS. Expression of c-myc, c-myb, and c-sis in fibroblasts from affected and unaffected skin of patients with systemic sclerosis. Autoimmunity 1993;16: 167-71.
    • (1993) Autoimmunity , vol.16 , pp. 167-171
    • Feghali, C.A.1    Boulware, D.W.2    Ferriss, J.A.3    Levy, L.S.4
  • 40
    • 42649130058 scopus 로고    scopus 로고
    • ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation
    • Ehrlich M, Sanchez C, Shao C, Nishiyama R, Kehrl J, Kuick R, et al. ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity 2008;41:253-71.
    • (2008) Autoimmunity , vol.41 , pp. 253-271
    • Ehrlich, M.1    Sanchez, C.2    Shao, C.3    Nishiyama, R.4    Kehrl, J.5    Kuick, R.6
  • 41
    • 48949083986 scopus 로고    scopus 로고
    • Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placentalspecific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing
    • Monk D, Wagschal A, Arnaud P, Muller PS, Parker-Katiraee L, Bourc'his D, et al. Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placentalspecific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing. Genome Res 2008;18:1270-81.
    • (2008) Genome Res , vol.18 , pp. 1270-1281
    • Monk, D.1    Wagschal, A.2    Arnaud, P.3    Muller, P.S.4    Parker-Katiraee, L.5    Bourc'his, D.6
  • 42
    • 31444453032 scopus 로고    scopus 로고
    • The ups and downs of BDNF in Rett syndrome
    • Sun YE, Wu H. The ups and downs of BDNF in Rett syndrome. Neuron 2006;49:321-3.
    • (2006) Neuron , vol.49 , pp. 321-323
    • Sun, Y.E.1    Wu, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.