Oxidative stress-mediated cytotoxicity and metabolism of T-2 toxin and deoxynivalenol in animals and humans: An update

Archives of Toxicology

Volumn 88, Issue 7, 2014, Pages 1309-1326

  Wu, Qing Hua ^a,b   Wang, Xu ^c   Yang, Wei ^d   Nüssler, Andreas K ^d   Xiong, Ling Yun ^e   Kuča, Kamil ^b,f   Dohnal, Vlastimil ^b   Zhang, Xiu Juan ^a   Yuan, Zong Hui ^c  

^a YANGTZE UNIVERSITY   (China)

^b UNIVERSITY OF HRADEC KRALOVE   (Czech Republic)

^c HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

Author keywords

Deoxynivalenol (DON); Metabolism; Metabolizing enzymes; Oxidative stress; ROS; T 2 toxin

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 2; CASPASE 3; CASPASE 8; CYTOCHROME P450; CYTOCHROME P450 3A22; CYTOCHROME P450 3A29; CYTOCHROME P450 3A37; CYTOCHROME P450 3A46; DEOXYNIVALENOL 3 BETA DEXTRO GLUCOSIDE; GAMMA GLUTAMYLTRANSFERASE; HT 2 TOXIN; MITOGEN ACTIVATED PROTEIN KINASE; NEOSOLANIOL; T 2 TOXIN; TRICHOTHECENE DERIVATIVE; UNCLASSIFIED DRUG; VOMITOXIN; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; BIOTRANSFORMATION; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; ENTEROCOCCUS; ENZYME METABOLISM; GLUCURONIDATION; HUMAN; HYDROXYLATION; IMMUNE RESPONSE; LACTOBACILLUS PLANTARUM; LIPID METABOLISM; LIPID PEROXIDATION; LIVER CELL; LIVER MICROSOME; LIVER TOXICITY; METABOLISM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; CHICKEN; DRUG EFFECTS; OXIDATION REDUCTION REACTION; RAT; SPECIES DIFFERENCE; TOXICITY;

ANIMALS; APOPTOSIS; CHICKENS; HUMANS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; T-2 TOXIN; TRICHOTHECENES;

EID: 84903379089     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1280-0     Document Type: Review

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