Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology

Toxicology

Volumn 153, Issue 1-3, 2000, Pages 83-104

  Mates J M ^a  

^a UNIVERSITY OF MÁLAGA   (Spain)

Author keywords

Antioxidants; Apoptosis; Catalase; Glutathione peroxidase; Reactive oxygen species; Superoxide dismutase

Indexed keywords

ANTIOXIDANT; CATALASE; DNA; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; M PROTEIN; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

AEROBIC METABOLISM; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL FUNCTION; CHEMICAL REACTION; CYTOTOXICITY; GENE CONTROL; LIPID PEROXIDATION; MUTAGENICITY; OXIDATION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CATALASE; GLUTATHIONE PEROXIDASE; HUMANS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 0034676493     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(00)00306-1     Document Type: Article

References (166)

1. Association of EC-SOD phenotype with the endothelial constitutive NO synthase polymorphism
2. Coordinate regulation of NAD(P)H:quinone oxidoreductase and glutathione-S-transferases in primary cultures of rat neurons and glia: Role of the antioxidant/electrophile responsive element
3. Intracerebroventricular administration of copper-zinc superoxide dismutase inhibits pulsatile luteinizing hormone secretion in ovariectomized ewes
4. GPX compensates for the hypersensitivity of Cu,Zn-SOD overproducers to oxidant stress
5. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury
6. Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?
7. Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin
8. Cerebrospinal fluid lipoproteins are more vulnerable to oxidation in Alzheimer's disease and are neurotoxic when oxidized ex vivo
9. The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease
10. Alzheimer's disease and oxidative stress: Implications for novel therapeutic approaches
11. Growth in iron-enriched medium partially compensates E. coli for the lack of Mn and Fe SOD
12. Antioxidant properties of melatoninan emerging mystery
13. Differences in the reducing power along the rat GI tract: Lower antioxidant capacity of the colon
14. Bcl-x(L) overexpresion attenuates glutathione depletion in FL5.12 cells following interleukin-3 withdrawal
15. Modifications of the antioxidant enzymes in relation to chromosome imbalances in human melanoma cell lines
16. Human cytoplasmic aconitase (Iron regulatory protein 1) is converted into its [3Fe-4S] form by hydrogen peroxide in vitro but is not activated for iron-responsive element binding
17. Oxidative stress and tumour cell proliferation
18. 2 in relation to proliferation and apoptosis in BHK-21 hamster fibroblasts
19. DNA excision repair profiles of normal and leukemic human lymphocytes: Functional analysis at the single-cell level
20. Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
21. Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells
22. Advanced glycation end products, oxidant stress and vascular lesions
23. Crystal structure of a novel human peroxidase enzyme at 2.0 Å resolution
24. Decreased zinc affinity of ALS-associated SOD mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite
25. pH-dependent DNA cleavage in permeabilized human fibroblasts
26. Metalloporphyrins are potent inhibitors of lipid peroxidation
27. Mice with a homozygous null mutation for the most abundant glutathione peroxidase. GPX1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide
28. Recent developments in the design of bioreductive drugs
29. Oxidative stress to rat lens in vitro: Protection by taurine
30. Nitric oxide inhibits APO-1/fas-mediated cell death
31. Biochemical characterization of selenium-containing catalytic antibody as a cytosolic glutathione peroxidase mimic
32. Glucose may induce cell death through a free radical-mediated mechanism
33. Oxidized lipoproteins activate NF-κB binding activity and apoptosis in PC12 cells
34. Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease
35. Antitumor activities of vanadium(IV), manganese(IV), iron(III), cobalt(II) and copper(II) complexes of 2-methylaminopyridine
36. Clastogenic factors in plasma of HIV-1 infected patients activate HIV-1 replication in vitro: Inhibition by superoxide dismutase
37. The heparin-binding domain of Ec-SOD is proteolytically processed intracellularly during biosynthesis
38. Induction of NO-dependent apoptosis in motor neurons by zinc-deficient SOD
39. Antioxidant properties of s-adenosyl-L-methionine: A proposed addition to organ storage fluids
40. Ramdom versus selective membrane phospholipid oxidation in apoptosis: Role of phosphatidylserine
41. Free radicals as mediators of neuronal injury
42. ApoE-containing HDL promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein (LRP)
43. Biological effects of resveratrol
44. Two adjacent AP-1-like binding sites form the electrophile-responsive element of the murine glutathione S-transferase Ya subunit gene
45. Oxidative stress caused by glycation of Cu,Zn-superoxide dismutase and its effects on intracellular components
46. Role of Hsp70 in regulation of stress-kinase JNK: Implications in apoptosis and aging
47. In vitro inhibition of superoxide anion production and SOD activity by zinc in human spermatozoa
48. Inactivation of both RNA binding and aconitase activities of iron regulatory protein-1 by quinone-induced oxidative stress
49. Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34
50. Antioxidant characterization. Methodology and mechanism
51. Vitamin C: Poison, prophylactic or panacea?
52. Nerve growth factor inhibits apoptosis induced by tumor necrosis factor in PC12 cells
53. Reduced fertility in female mice lacking Cu/Zn-SOD
54. Bcl-2 functions in an antioxidant pathway to prevent apoptosis
55. LRP mediates apolipoprotein E-dependent neurite outgrowth in a CNS-derived neuronal cell line
56. Probing the active site of human Mn-SOD: The role of glutamine 143
57. The Ab peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
58. 2 production and metal reduction
59. Genomic instability and catalase gene amplification induced by chronic exposure to oxidative stress
60. Expression of apolipoprotein E during nerve degeneration and regeneration
61. Lipoprotein uptake by neuronal growth cones in vitro
62. Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase
63. Importance of catalase in the adaptive response to hydrogen peroxide: Analysis of acatalasaemic Saccharomyces cerevisiae
64. Antioxidant response element
65. Human NAD(P)H:quinone oxidoreductase2. Gene structure, activity, and tissue-specific expression
66. SODs in relation to the overall survival of colorectal cancer patients
67. Effect of nitric oxide on hemoprotein-catalyzed oxidative reactions
68. Bioorganometallic chemistry synthesis and antitumor activity of cobalt carbonyl complexes
69. Synthetic antioxidants: Biochemical actions and interference with radiation, toxic compounds, chemical mutagens and chemical carcinogens
70. Signal transduction by the neurotrophin receptors
71. Oxidized low-density lipoprotein induces neuronal cell death: Implication for calcium, reactive oxygen species and caspases
72. Do nitroxide antioxidants act as scavengers of superoxide or as superoxide dismutase mimics?
73. Protein kinase cascades activated by stress and inflammatory cytokines
74. Nascent astrocyte particles differ from lipoproteins in CSF
75. Molecular manipulations of extracellular superoxide dismutase: Functional importance for learning
76. Paraquat induced activation of transcription factor AP-1 and apoptosis in PC12 cells
77. 2
78. Oxidation of catalase by singlet oxygen
79. An assessment of oxidative damage to proteins, lipids and DNA in brain from patients with Alzheimer's disease
80. Prevention of mitochondrial injury by Mn-SOD reveals a primary mechanism for alkaline-induced cell death
81. Antioxidant enzymes and their implications in pathophysiologic processes
82. Antioxidant enzymes and human diseases
83. Antioxidant enzymatic activities in human blood cells after an allergic reaction to pollen or house dust mite
84. Role of ROS in apoptosis. Possible implications for cancer therapy
85. Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease
86. Signal transduction pathways to apoptosis
87. Cu/Zn SOD deficiency potentiates hearing loss and cochlear pathology in aged 129,CD-1 mice
88. Selenium: An essential element for immune function
89. Metabolism and function of glutathione
90. Glutathione-ascorbic acid antioxidant system in animals
91. A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
92. A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells
93. The role of oxidative stress and NF(B activation in late diabetic complications
94. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
95. Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-alpha and estrogen receptor-beta
96. Glutathione S-transferase pi in colorectal tumors is predictive for overall survival
97. Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence
98. An insight into Dupuytren's contracture
99. Cell-specific induction of hsp72-mediated protection by glutamine against oxidant injury in IEC18 cells
100. Liposome-encapsulated superoxide dismutase prevents liver necrosis induced by acetaminophen
101. Oxidative injury and its defense system in vivo
102. Antioxidant-derived prooxidant formation from ubiquinol
103. Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse
104. Role of the well-known basic and recently discovered acidic glutathione S-transferases in the control of genotoxic metabolites
105. Functional cooperativity between two TPA responsive elements in undifferentiated F9 embryonic stem cells
106. Rapid responses to oxidative stress mediated by iron regulatory protein
107. Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress
108. Activation of iron regulatory protein-1 by oxidative stress in vitro
109. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
110. Sequence specificity and reactivity of the binding of phenazine-tethered platinum complexes to DNA
111. Superoxide dismutase activity of antibodies purified from the human arteries and atherosclerotic lesions
112. Neural tube defects in embryos of diabetic mice: Role of the Pax-3 gene and apoptosis
113. Cholesterol synthesis and lipoprotein reuptake during synaptic remodeling in hippocampus in adult rats
114. The electrophile counterattack response: Protection against neoplasia and toxicity
115. Genetic neurodegenerative diseases: The human illness and transgenic models
116. Antioxidant response element-mediated 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induction of human NAD(P)H:quinone oxidoreductase 1 gene expression
117. Effects of vitamins A, C, and E on aflatoxin B1-induced mutagenesis in Salmonella typhimurium TA-98 and TA-100
118. DT-diaphorase: Possible roles in cancer chemotherapy and carcinogenesis
119. Motor neurons in Cu/ZnSOD-deficient mice develop normally but exhibit enhanced cell death after axonal injury
120. Regulation of glutathione S-transferase Ya subunit gene expression: Identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds
121. Glutathione S-transferases, structure, regulation, and therapeutic implications
122. Neurons undergo apoptosis in animal and cell culture models of diabetes
123. A nonpeptidyl mimic of SOD with therapeutic activity in rats
124. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
125. Enhanced alloxan-induced beta-cell damage and delayed recovery from hyperglycemia in mice lacking extracellular-superoxide dismutase
126. C/EBP alpha and C/EBP beta play similar roles in the transcription of the human Cu/Zn SOD gene
127. Amrita Bindu: A salt-spice-herbal health food supplement for the prevention of nitrosamine induced depletion of antioxidants
128. Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase
129. Cells enriched for catalase are sensitized to the toxicities of bleomycin, adriamycin, and paraquat
130. Concepts and developments in radiosensitization of mammalian cells
131. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in onset familial Alzheimer disease
132. Binding of human Apolipoprotein E to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
133. Apolipoprotein E and Alzheimer's disease
134. Oxidative stress and neurodegenerative disorders
135. Functional roles of phospholipids of synaptosomal membrane
136. Chemoprotection against cancer by phase 2 enzyme induction
137. Oxygen free radical scavenger properties of dehydroepiandrosterone
138. Identification of the major oxidatively damaged proteins in Escherichia coli cells exposed to oxidative stress
139. Glutathione peroxidase protects cultured mammalian cells from the toxicity of adriamycin and paraquat
140. Cytotoxicity, radiosensitization, antitumor activity, and interaction with hyperthermia of a Co(III) mustard complex
141. UDP-glucuronosyltransferases: A family of detoxifying enzymes
142. Apoptosis in the pathogenesis and treatment of disease
143. Low glutathione and high iron govern the susceptibility of oligodendroglial precursors to oxidative stress
144. Expression of manganese superoxide dismutase reduces tumor control radiation dose: Gene-radiotherapy
145. Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts
146. Sensitivity of K562 and HL-60 cells to edelfosine, an ether lipid drug, correlates with production of reactive oxygen species
147. Overexpression of human copper,zinc-superoxide dismutase (SOD-1) prevents postischemic injury
148. Functional antioxidant responsive elements
149. Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage
150. Manganese-based SOD mimetics inhibit neutrophil infiltration in vivo
151. Cu/Zn-SOD and Mn-SOD in human tissues and human malignant tumors
152. A glutamate bridge is essential for dimer stability and metal selectivity in Mn-SOD
153. Dose-related inhibition of aflatoxin B1 induced hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene
154. AP-2-mediated regulation of human NAD(P)H: Quinone oxidoreductase 1 (NQO1) gene expression
155. Glycation-induced inactivation and loss of antigenicity of catalase and superoxide dismutase
156. Superoxide generation in v-Ha-ras-transduced human keratinocyte HaCaT cells
157. The antioxidant vitamin E modulates amyloid beta-peptide-induced creatine kinase activity inhibition and increased protein oxidation: Implications for the free radical hypothesis of Alzheimer's disease
158. A novel nickel-containing superoxide dismutase from Streptomyces spp.
159. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
160. Diabetes-induced apoptosis in rat kidney
161. Redox gene therapy protects human IB-3 lung epithelial cells against ionizing radiation-induced apoptosis