메뉴 건너뛰기




Volumn 62, Issue 1, 2014, Pages 288-296

Metabolism, distribution, and excretion of deoxynivalenol with combined techniques of radiotracing, high-performance liquid chromatography ion trap time-of-flight mass spectrometry, and online radiometric detection

Author keywords

deoxynivalenol; disposition; metabolism; tritium labeled

Indexed keywords

COMBINED TECHNIQUES; DEOXYNIVALENOL; DISPOSITION; GASTROINTESTINAL TRACT; METABOLITE PROFILES; RADIOMETRIC DETECTION; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; RADIOTRACER METHOD;

EID: 84892154352     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf4047946     Document Type: Article
Times cited : (57)

References (28)
  • 1
    • 34547830857 scopus 로고    scopus 로고
    • Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients
    • Binder, E. M.; Tan, L. M.; Chin, L. J.; Handl, J.; Richard, J. Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients Anim. Feed Sci. Technol. 2007, 137, 265-282
    • (2007) Anim. Feed Sci. Technol. , vol.137 , pp. 265-282
    • Binder, E.M.1    Tan, L.M.2    Chin, L.J.3    Handl, J.4    Richard, J.5
  • 2
    • 34547840232 scopus 로고    scopus 로고
    • Deoxynivalenol: Toxicity, mechanisms and animal health risks
    • Pestka, J. J. Deoxynivalenol: Toxicity, mechanisms and animal health risks Anim. Feed Sci. Technol. 2007, 137, 283-298
    • (2007) Anim. Feed Sci. Technol. , vol.137 , pp. 283-298
    • Pestka, J.J.1
  • 3
    • 70849100264 scopus 로고    scopus 로고
    • Mechanisms of deoxynivalenol-induced gene expression and apoptosis
    • Pestka, J. J. Mechanisms of deoxynivalenol-induced gene expression and apoptosis Food Addit. Contam., Part A 2008, 25, 1128-1140
    • (2008) Food Addit. Contam., Part A , vol.25 , pp. 1128-1140
    • Pestka, J.J.1
  • 8
    • 0021092231 scopus 로고
    • Structure of a novel metabolite from deoxynivalenol, a trichothecene mycotoxin, in animals
    • Yoshizawa, T.; Takeda, H.; Ohi, T. Structure of a novel metabolite from deoxynivalenol, a trichothecene mycotoxin, in animals Agric. Biol. Chem. 1983, 47, 2133-2135
    • (1983) Agric. Biol. Chem. , vol.47 , pp. 2133-2135
    • Yoshizawa, T.1    Takeda, H.2    Ohi, T.3
  • 9
    • 0026450895 scopus 로고
    • Microbial transformation of deoxynivalenol (vomitoxin)
    • He, P.; Young, L. G.; Forsberg, C. Microbial transformation of deoxynivalenol (vomitoxin) Appl. Environ. Microb. 1992, 58, 3857-3863
    • (1992) Appl. Environ. Microb. , vol.58 , pp. 3857-3863
    • He, P.1    Young, L.G.2    Forsberg, C.3
  • 10
    • 33751227516 scopus 로고    scopus 로고
    • Degradation of trichothecene mycotoxins by chicken intestinal microbes
    • Young, J. C.; Zhou, T.; Yu, H.; Gong, J. Degradation of trichothecene mycotoxins by chicken intestinal microbes Food Chem. Toxicol. 2007, 45, 136-143
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 136-143
    • Young, J.C.1    Zhou, T.2    Yu, H.3    Gong, J.4
  • 12
    • 84877329386 scopus 로고    scopus 로고
    • New insights into the human metabolism of the Fusarium mycotoxins deoxynivalenol and zearalenone
    • Warth, B.; Sulyok, M.; Berthiller, F.; Schuhmacher, R.; Krska, R. New insights into the human metabolism of the Fusarium mycotoxins deoxynivalenol and zearalenone Toxicol. Lett. 2013, 220, 88-94
    • (2013) Toxicol. Lett. , vol.220 , pp. 88-94
    • Warth, B.1    Sulyok, M.2    Berthiller, F.3    Schuhmacher, R.4    Krska, R.5
  • 14
    • 0023221350 scopus 로고
    • Metabolic fate and elimination in milk, urine and bile of deoxynivalenol following administration to lactating sheep
    • Preluskya, D. B.; Veiraa, D. M.; Trenholma, H. L.; Fostera, B. C. Metabolic fate and elimination in milk, urine and bile of deoxynivalenol following administration to lactating sheep J. Environ. Sci. Health, Part B 1987, 22, 125-148
    • (1987) J. Environ. Sci. Health, Part B , vol.22 , pp. 125-148
    • Preluskya, D.B.1    Veiraa, D.M.2    Trenholma, H.L.3    Fostera, B.C.4
  • 15
    • 0028341124 scopus 로고
    • Production of high quantities of 3-acetyldeoxynivalenol and deoxynivalenol
    • Altpeter, F.; Posselt, U. K. Production of high quantities of 3-acetyldeoxynivalenol and deoxynivalenol Appl. Microbiol. Biotechnol. 1994, 41, 384-387
    • (1994) Appl. Microbiol. Biotechnol. , vol.41 , pp. 384-387
    • Altpeter, F.1    Posselt, U.K.2
  • 17
    • 0343346049 scopus 로고
    • 1H nuclear magnetic resonance study of derivatives of 3-hydroxy-12,13-epoxytrichothec-9-enes
    • 1H nuclear magnetic resonance study of derivatives of 3-hydroxy-12,13-epoxytrichothec-9- enes Can. J. Chem. 1987, 65, 2254-2262
    • (1987) Can. J. Chem. , vol.65 , pp. 2254-2262
    • Savard, M.1    Blackwell, B.A.2    Greenhalgh, R.3
  • 18
    • 33645463689 scopus 로고    scopus 로고
    • Stable isotope dilution analysis of the Fusarium mycotoxins deoxynivalenol and 3-acetyldeoxynivalenol
    • Bretz, M.; Beyer, M.; Cramer, B.; Humpf, H. Stable isotope dilution analysis of the Fusarium mycotoxins deoxynivalenol and 3-acetyldeoxynivalenol Mol. Nutr. Food Res. 2006, 50, 251-260
    • (2006) Mol. Nutr. Food Res. , vol.50 , pp. 251-260
    • Bretz, M.1    Beyer, M.2    Cramer, B.3    Humpf, H.4
  • 19
    • 0028568256 scopus 로고
    • Regioselective reactions with derivatives of the trichothecene mycotoxins, nivalenol and vomitoxin
    • Grove, J. F. Regioselective reactions with derivatives of the trichothecene mycotoxins, nivalenol and vomitoxin J. Nat. Prod. 1994, 57, 1491-1497
    • (1994) J. Nat. Prod. , vol.57 , pp. 1491-1497
    • Grove, J.F.1
  • 20
    • 33747864478 scopus 로고    scopus 로고
    • Using a tritiated compound to elucidate its preclinical metabolic and excretory pathways in vivo: Exploring tritium exchange risk
    • Shaffer, C. L.; Gunduz, M.; Thornburgh, B. A.; Fate, G. D. Using a tritiated compound to elucidate its preclinical metabolic and excretory pathways in vivo: Exploring tritium exchange risk Drug Metab. Dispos. 2006, 34, 1615-1623
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 1615-1623
    • Shaffer, C.L.1    Gunduz, M.2    Thornburgh, B.A.3    Fate, G.D.4
  • 22
    • 77955653001 scopus 로고    scopus 로고
    • Determination of deoxynivalenol-sulfonate (DONS) in cereals by hydrophilic interaction chromatography coupled to tandem mass spectrometry
    • Beyer, M.; Dänicke, S.; Rohweder, D.; Humpf, H. Determination of deoxynivalenol-sulfonate (DONS) in cereals by hydrophilic interaction chromatography coupled to tandem mass spectrometry Mycol. Res. 2010, 26, 109-117
    • (2010) Mycol. Res. , vol.26 , pp. 109-117
    • Beyer, M.1    Dänicke, S.2    Rohweder, D.3    Humpf, H.4
  • 23
    • 33749033607 scopus 로고    scopus 로고
    • Identification of sulfation sites of metabolites and prediction of the compounds' biological effects
    • Yi, L.; Dratter, J.; Wang, C.; Tunge, J. A; Desaire, H. Identification of sulfation sites of metabolites and prediction of the compounds' biological effects Anal. Bioanal. Chem. 2006, 386, 666-674
    • (2006) Anal. Bioanal. Chem. , vol.386 , pp. 666-674
    • Yi, L.1    Dratter, J.2    Wang, C.3    Tunge, J.A.4    Desaire, H.5
  • 25
    • 0141569644 scopus 로고    scopus 로고
    • Metabolism of (R)-(+)-menrhofuran in fischer-344 rats: Identification of sulfonic acid metabolites
    • Chen, L. J.; Lebetkin, E. H.; Burka, L. T. Metabolism of (R)-(+)-menrhofuran in fischer-344 rats: Identification of sulfonic acid metabolites Drug Metab. Dispos. 2003, 31, 1208-1213
    • (2003) Drug Metab. Dispos. , vol.31 , pp. 1208-1213
    • Chen, L.J.1    Lebetkin, E.H.2    Burka, L.T.3
  • 26
    • 77953362502 scopus 로고    scopus 로고
    • Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry
    • Jirásko, R.; Holčapek, M.; Vrublová, E.; Ulrichová, J.; Šimánek, V. Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry J. Chromotogr., A 2010, 4100-4108
    • (2010) J. Chromotogr., A , pp. 4100-4108
    • Jirásko, R.1    Holčapek, M.2    Vrublová, E.3    Ulrichová, J.4    Šimánek, V.5
  • 27
    • 79952852572 scopus 로고    scopus 로고
    • Metabolism of gambogic acid in rats: A rare intestinal metabolic pathway responsible for its final disposition
    • Yang, J.; Ding, L.; Hu, L.; Qian, W.; Jin, S.; Sun, X.; Wang, Z.; Xiao, W. Metabolism of gambogic acid in rats: A rare intestinal metabolic pathway responsible for its final disposition Drug Metab. Dispos. 2011, 39, 617-626
    • (2011) Drug Metab. Dispos. , vol.39 , pp. 617-626
    • Yang, J.1    Ding, L.2    Hu, L.3    Qian, W.4    Jin, S.5    Sun, X.6    Wang, Z.7    Xiao, W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.