-
1
-
-
0027306797
-
Trichothecene biosynthesis in Fusarium species: Chemistry, genetics, and significance
-
Desjardins, A. E., Hohn, T. M., and McCormick, S. P. (1993) Trichothecene biosynthesis in Fusarium species: Chemistry, genetics, and significance. Microbiol. Rev. 57, 595-604 (Pubitemid 23262510)
-
(1993)
Microbiological Reviews
, vol.57
, Issue.3
, pp. 595-604
-
-
Desjardins, A.E.1
Hohn, T.M.2
McCormick, S.P.3
-
3
-
-
0023107903
-
Metabolism of three trichothecene mycotoxins, T-2 toxin, diacetoxyscirpenol and deoxynivalenol, by bovine rumen microorganisms
-
Swanson, S. P., Nicoletti, J., Rood, H. D., Jr., Buck, W. B., Cote, L. M., and Yoshizawa, T. (1987) Metabolism of three trichothecene mycotoxins, T-2 toxin, diacetoxyscirpenol and deoxynivalenol, by bovine rumen microorganisms. J. Chromatogr. 414, 335-342 (Pubitemid 17041684)
-
(1987)
Journal of Chromatography - Biomedical Applications
, vol.414
, Issue.2
, pp. 335-342
-
-
Swanson, S.P.1
Nicoletti, J.2
Rood Jr., H.D.3
-
4
-
-
0024238373
-
The role of intestinal microflora in the metabolism of trichothecene mycotoxins
-
DOI 10.1016/0278-6915(88)90021-X
-
Swanson, S. P., Helaszek, C., Buck, W. B., Rood, H. D., Jr., and Haschek, W. M. (1988) The role of intestinal microflora in the metabolism of trichothecene mycotoxins. Food Chem. Toxicol. 26, 823-829 (Pubitemid 19026279)
-
(1988)
Food and Chemical Toxicology
, vol.26
, Issue.10
, pp. 823-829
-
-
Swanson, S.P.1
Helaszek, C.2
Buck, W.B.3
Rood Jr., H.D.4
Haschek, W.M.5
-
5
-
-
0027244640
-
Metabolism and pharmacokinetics of T-2 toxin and related trichothecenes
-
Yagen, B., and Bialer, M. (1993) Metabolism and pharmacokinetics of T-2 toxin and related trichothecenes. Drug Metab. Rev. 25, 281-323 (Pubitemid 23236200)
-
(1993)
Drug Metabolism Reviews
, vol.25
, Issue.3
, pp. 281-323
-
-
Yagen, B.1
Bialer, M.2
-
6
-
-
28444468526
-
Determination of 12 type A and B trichothecenes in cereals by liquid chromatography-electrospray ionization tandem mass spectrometry
-
DOI 10.1021/jf051501c
-
Klötzel, M., Gutsche, B., Lauber, U., and Humpf, H. U. (2005) Determination of 12 type A and B trichothecenes in cereals by liquid chromatography-electrospray ionization tandem mass spectrometry. J. Agric. Food Chem. 53, 8904-8910 (Pubitemid 41735651)
-
(2005)
Journal of Agricultural and Food Chemistry
, vol.53
, Issue.23
, pp. 8904-8910
-
-
Klotzel, M.1
Gutsche, B.2
Lauber, U.3
Humpf, H.-U.4
-
7
-
-
29944435687
-
Natural occurrence of 16 Fusarium toxins in grains and feedstuffs of plant origin from Germany
-
DOI 10.1007/s11046-005-0199-7
-
Schollenberger, M., Müller, H. M., Rüfle, M., Suchy, S., Plank, S., and Drochner, W. (2006) Natural occurrence of 16 Fusarium toxins in grains and feed stuffs of plant origin from Germany. Mycopathologia 161, 43-52 (Pubitemid 43042221)
-
(2006)
Mycopathologia
, vol.161
, Issue.1
, pp. 43-52
-
-
Schollenberger, M.1
Muller, H.-M.2
Rufle, M.3
Suchy, S.4
Plank, S.5
Drochner, W.6
-
8
-
-
0038394347
-
Trichothecenes in the environment: Relevance to human health
-
Sudakin, D. L. (2003) Trichothecenes in the environment: Relevance to human health. Toxicol. Lett. 143, 97-107
-
(2003)
Toxicol. Lett.
, vol.143
, pp. 97-107
-
-
Sudakin, D.L.1
-
9
-
-
1842855995
-
Toxicological evaluation of trichothecenes in animal feed
-
DOI 10.1016/j.anifeedsci.2003.08.008, PII S0377840103002554
-
Eriksen, G. S., and Pettersson, H. (2004) Toxicological evaluation of trichothecenes in animal feed. Anim. Feed Sci. Tech. 114, 205-239 (Pubitemid 38484824)
-
(2004)
Animal Feed Science and Technology
, vol.114
, Issue.1-4
, pp. 205-239
-
-
Eriksen, G.S.1
Pettersson, H.2
-
10
-
-
42149116916
-
T-2 toxin: Incidence and toxicity in poultry
-
DOI 10.2478/10004-1254-59-2008-1843, PII 16557625H36712L2
-
Sokolović, M., Garaj-Vrhovac, V., and Simpraga, B. (2008) T-2 toxin: Incidence and toxicity in poultry. Arh. Hig. Rada. Toksikol. 59, 43-52 (Pubitemid 351534448)
-
(2008)
Arhiv za Higijenu Rada i Toksikologiju
, vol.59
, Issue.1
, pp. 43-52
-
-
Sokolovic, M.1
Garaj-Vrhovac, V.2
Simpraga, B.3
-
11
-
-
4444357135
-
Report from SCOOP task 3.2.10 "collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by the population of EU member states" Subtask: Trichothecenes
-
DOI 10.1016/j.toxlet.2004.04.045, PII S037842740400253X
-
Schothorst, R. C., and Egmond, H. P. (2004) Report from SCOOP task 3.2.10 "collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by the population of EU member states"Subtask: Trichothecenes. Toxicol. Lett. 153, 133-143 (Pubitemid 39165758)
-
(2004)
Toxicology Letters
, vol.153
, Issue.1
, pp. 133-143
-
-
Schothorst, R.C.1
Van Egmond, H.P.2
-
12
-
-
4444268646
-
Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: Unraveling a paradox
-
DOI 10.1016/j.toxlet.2004.04.023, PII S0378427404002449
-
Pestka, J. J., Zhou, H. R., Moon, Y., and Chung, Y. J. (2004) Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes unraveling a paradox. Toxicol. Lett. 153, 61-73 (Pubitemid 39165750)
-
(2004)
Toxicology Letters
, vol.153
, Issue.1
, pp. 61-73
-
-
Pestka, J.J.1
Zhou, H.-R.2
Moon, Y.3
Chung, Y.J.4
-
13
-
-
84994997942
-
Protective effect of antioxidants against free radical-mediated lipid peroxidation induced by DON or T-2 toxin
-
Rizzo, A. F., Atroshi, F., Ahotupa, M., Sankari, S., and Elovaara, E. (1994) Protective effect of antioxidants against free radical-mediated lipid peroxidation induced by DON or T-2 toxin. Zentralbl Veterinarmed A 41, 81-90
-
(1994)
Zentralbl Veterinarmed A
, vol.41
, pp. 81-90
-
-
Rizzo, A.F.1
Atroshi, F.2
Ahotupa, M.3
Sankari, S.4
Elovaara, E.5
-
14
-
-
33750302373
-
T-2 toxin impairs murine immune response to respiratory reovirus and exacerbates viral bronchiolitis
-
DOI 10.1016/j.taap.2006.08.007, PII S0041008X06002651
-
Li, M., Harkema, J. R., Islam, Z., Cuff, C. F., and Pestka, J. J. (2006) T-2 toxin impairs murine immune response to respiratory reovirus and exacerbates viral broncholitis. Toxicol. Appl. Pharmacol. 217, 76-85 (Pubitemid 44635665)
-
(2006)
Toxicology and Applied Pharmacology
, vol.217
, Issue.1
, pp. 76-85
-
-
Li, M.1
Harkema, J.R.2
Islam, Z.3
Cuff, C.F.4
Pestka, J.J.5
-
15
-
-
0023859029
-
Alteration of multiple cell membrane functions in L-6 myoblasts by T-2 toxin: An important mechanism of action
-
Bunner, D. L., and Morris, E. R. (1988) Alteration of multiple cell membrane functions in L-6 myoblasts by T-2 toxin: An important mechanism of action. Toxicol. Appl. Pharmacol. 92, 113-121 (Pubitemid 18049696)
-
(1988)
Toxicology and Applied Pharmacology
, vol.92
, Issue.1
, pp. 113-121
-
-
Bunner, D.L.1
Morris, E.R.2
-
16
-
-
18344375872
-
Immunopathological effect of the mycotoxins cyclopiazonic acid and T-2 toxin on broiler chicken
-
DOI 10.1007/s11046-004-7321-0
-
Kamalavenkatesh, P., Vairamuthu, S., Balachandran, C., Manohar, B. M., and Raj, G. D. (2005) Immunopathological effect of the mycotoxins cyclopiazonic acid and T-2 toxin on broiler chicken. Mycopathologia 159, 273-279 (Pubitemid 40633933)
-
(2005)
Mycopathologia
, vol.159
, Issue.2
, pp. 273-279
-
-
Kamalavenkatesh, P.1
Vairamuthu, S.2
Balachandran, C.3
Murali, M.B.4
Dhinakar, R.G.5
-
17
-
-
56049092723
-
Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells
-
Bouaziz, C., Sharaf El Dein, O., El Golli, E., Abid-Essefi, S., Brenner, C., Lemaire, C., and Bacha, H. (2008) Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells. Toxicology 254, 19-28
-
(2008)
Toxicology
, vol.254
, pp. 19-28
-
-
Bouaziz, C.1
Sharaf El Dein, O.2
El Golli, E.3
Abid-Essefi, S.4
Brenner, C.5
Lemaire, C.6
Bacha, H.7
-
18
-
-
0022587904
-
Metabolism of T-2 mycotoxin by cultured cells
-
Trusal, L. R. (1986) Metabolism of T-2 mycotoxin by cultured cells. Toxicon 24, 597-603
-
(1986)
Toxicon
, vol.24
, pp. 597-603
-
-
Trusal, L.R.1
-
19
-
-
0006462050
-
Disposition of T-2 toxin, a trichothecene mycotoxin, in intravascularly dosed swine
-
Corley, R. A., Swanson, S. P., Gullo, G. J., Johnson, L., Beasley, V. R., and Buck, W. B. (1986) Disposition of T-2 toxin, a trichothecene mycotoxin, in intravascularly dosed swine. J. Agric. Food Chem. 34, 868-875
-
(1986)
J. Agric. Food Chem.
, vol.34
, pp. 868-875
-
-
Corley, R.A.1
Swanson, S.P.2
Gullo, G.J.3
Johnson, L.4
Beasley, V.R.5
Buck, W.B.6
-
20
-
-
0015948472
-
In vitro metabolism of T-2 toxin
-
Ellison, R. A., and Kotsonis, F. N. (1974) In vitro metabolism of T-2 toxin. Appl. Microbiol. 27, 423-424
-
(1974)
Appl. Microbiol.
, vol.27
, pp. 423-424
-
-
Ellison, R.A.1
Kotsonis, F.N.2
-
21
-
-
0017745629
-
Metabolism of trichothecene mycotoxins I
-
Ohta, M., Ishii, K., and Ueno, Y. (1977) Metabolism of trichothecene mycotoxins I. J. Biochem. 82, 1591-1598
-
(1977)
J. Biochem.
, vol.82
, pp. 1591-1598
-
-
Ohta, M.1
Ishii, K.2
Ueno, Y.3
-
22
-
-
77951431126
-
Metabolic pathways of trichothecenes
-
Wu, Q., Dohnal, V., Huang, L., Kuca, K., and Yuan, Z. (2010) Metabolic pathways of trichothecenes. Drug Metab. Rev. 42, 250-267
-
(2010)
Drug Metab. Rev.
, vol.42
, pp. 250-267
-
-
Wu, Q.1
Dohnal, V.2
Huang, L.3
Kuca, K.4
Yuan, Z.5
-
23
-
-
75349087626
-
Chemical and biological transformations for detoxification of trichothecene mycotoxins in human and animal food chains: A review
-
He, J., Zhou, T., Young, J. C., Boland, G. J., and Scott, P. M. (2010) Chemical and biological transformations for detoxification of trichothecene mycotoxins in human and animal food chains: A review. Trends in Food Sci. Technol. 21, 67-76
-
(2010)
Trends in Food Sci. Technol.
, vol.21
, pp. 67-76
-
-
He, J.1
Zhou, T.2
Young, J.C.3
Boland, G.J.4
Scott, P.M.5
-
24
-
-
0033199820
-
Characterization of drug metabolizing activities in pig hepatocytes for use in bioartificial liver devices: Comparison with other hepatic cellular models
-
DOI 10.1016/S0168-8278(99)80049-X
-
Donato, M. T., Castell, J. V., and Gómez-Lechón, M. J. (1999) Characterization of drug metabolizing activities in pig hepatocytes for use in bioartificial liver devices: Comparison with other hepatic cellular models. J. Hepatol. 31, 542-549 (Pubitemid 29408740)
-
(1999)
Journal of Hepatology
, vol.31
, Issue.3
, pp. 542-549
-
-
Donato, M.T.1
Castell, J.V.2
Gomez-Lechon, M.J.3
-
25
-
-
27144452891
-
Systems toxicology: Applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology
-
DOI 10.1586/14789450.2.5.767
-
Heijne, W. H., Kienhuis, A. S., Van Ommen, B., Stierum, R. H., and Groten, J. P. (2005) Systems toxicology: applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology. Expert Rev. Proteomics 2, 767-780 (Pubitemid 41492397)
-
(2005)
Expert Review of Proteomics
, vol.2
, Issue.5
, pp. 767-780
-
-
Heijne, W.H.M.1
Kienhuis, A.S.2
Van Ommen, B.3
Stierum, R.H.4
Groten, J.P.5
-
26
-
-
71149109964
-
Proteomics identification of azaspiracid toxin biomarkers in blue mussels, Mytilus edulis
-
Nzoughet, J. K., Hamilton, J. T., Botting, C. H., Douglas, A., Devine, L., Nelson, J., and Elliott, C. T. (2009) Proteomics identification of azaspiracid toxin biomarkers in blue mussels, Mytilus edulis. Mol. Cell Proteomics. 8, 1811-1822
-
(2009)
Mol. Cell Proteomics
, vol.8
, pp. 1811-1822
-
-
Nzoughet, J.K.1
Hamilton, J.T.2
Botting, C.H.3
Douglas, A.4
Devine, L.5
Nelson, J.6
Elliott, C.T.7
-
27
-
-
3042733910
-
2+in Schizosaccharomyces pombe through amino acid-coded mass tagging and liquid chromatography tandem mass spectrometry
-
2+ in Schizosaccharomyces pombe through amino acid-coded mass tagging and liquid chromatography tandem mass spectrometry. Mol. Cell Proteomics. 3, 596-607
-
(2004)
Mol. Cell Proteomics
, vol.3
, pp. 596-607
-
-
Bae, W.1
Chen, X.2
-
28
-
-
0017101039
-
Preparation of isolated rat liver cells
-
Seglen, P. O. (1976) Preparation of isolated rat liver cells. Methods Cell Biol. 13, 29-83
-
(1976)
Methods Cell Biol.
, vol.13
, pp. 29-83
-
-
Seglen, P.O.1
-
29
-
-
77956870562
-
The catalytic activity of cytochrome P450 3A22 is critical for the metabolism of T-2 toxin in porcine reservoirs
-
Ge, X. H., Wang, J. P., Liu, J., Jiang, J., Lin, H. N., Wu, J., Ouyang, M., Tang, H. Q., Zheng, M., Liao, M., and Deng, Y. Q. (2010) The catalytic activity of cytochrome P450 3A22 is critical for the metabolism of T-2 toxin in porcine reservoirs. Catal. Comm. 12, 71-75
-
(2010)
Catal. Comm.
, vol.12
, pp. 71-75
-
-
Ge, X.H.1
Wang, J.P.2
Liu, J.3
Jiang, J.4
Lin, H.N.5
Wu, J.6
Ouyang, M.7
Tang, H.Q.8
Zheng, M.9
Liao, M.10
Deng, Y.Q.11
-
30
-
-
0035710746
-
-Delta Delta CT method
-
DOI 10.1006/meth.2001.1262
-
Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408 (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
32
-
-
0026485793
-
High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein
-
Fisher, C. W., Shet, M. S., Caudle, D. L., Martin-Wixtrom, C. A., and Estabrook, R. W. (1992) High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein. Proc. Natl. Acad. Sci. U.S.A. 89, 10817-10821
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10817-10821
-
-
Fisher, C.W.1
Shet, M.S.2
Caudle, D.L.3
Martin-Wixtrom, C.A.4
Estabrook, R.W.5
-
33
-
-
70249116388
-
Chromatographic assays of drug oxidation by human cytochrome P450 3A4
-
Sohl, C. D., Cheng, Q., and Guengerich, F. P. (2009) Chromatographic assays of drug oxidation by human cytochrome P450 3A4. Nat. Protoc. 4, 1252-1257
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1252-1257
-
-
Sohl, C.D.1
Cheng, Q.2
Guengerich, F.P.3
-
34
-
-
78951490188
-
CYP3As catalyze nifedipine oxidation in pig liver microsomes: Enzyme kinetics, inhibition and functional expression
-
Jiang, J., Wang, J. P., Cai, H., Li, K. B., and Deng, Y. Q. (2011) CYP3As catalyze nifedipine oxidation in pig liver microsomes: Enzyme kinetics, inhibition and functional expression. Catal. Comm. 12, 694-697
-
(2011)
Catal. Comm.
, vol.12
, pp. 694-697
-
-
Jiang, J.1
Wang, J.P.2
Cai, H.3
Li, K.B.4
Deng, Y.Q.5
-
35
-
-
0242559054
-
Pathway studio - The analysis and navigation of molecular networks
-
DOI 10.1093/bioinformatics/btg290
-
Nikitin, A., Egorov, S., Daraselia, N., and Mazo, I. (2003) Pathway studio-the analysis and navigation of molecular networks. Bioinformatics 19, 2155-2157 (Pubitemid 37408171)
-
(2003)
Bioinformatics
, vol.19
, Issue.16
, pp. 2155-2157
-
-
Nikitin, A.1
Egorov, S.2
Daraselia, N.3
Mazo, I.4
-
36
-
-
0030741845
-
Tissue inhibitor of metalloproteinase-1 in the liver of patients with chronic liver disease
-
DOI 10.1016/S0168-8278(97)80454-0
-
Murawaki, Y., Ikuta, Y., Idobe, Y., Kitamura, Y., and Kawasaki, H. (1997) Tissue inhibitor of metalloproteinase-1 in the liver of patients with chronic liver disease. J. Hepatol. 26, 1213-1219 (Pubitemid 27346632)
-
(1997)
Journal of Hepatology
, vol.26
, Issue.6
, pp. 1213-1219
-
-
Murawaki, Y.1
Ikuta, Y.2
Idobe, Y.3
Kitamura, Y.4
Kawasaki, H.5
-
37
-
-
0035313376
-
Reduced early alcohol-induced liver injury in CD14-deficient mice
-
Yin, M., Bradford, B. U., Wheeler, M. D., Uesugi, T., Froh, M., Goyert, S. M., and Thurman, R. G. (2001) Reduced early alcohol-induced liver injury in CD14-deficient mice. J. Immunol. 166, 4737-4742 (Pubitemid 32233762)
-
(2001)
Journal of Immunology
, vol.166
, Issue.7
, pp. 4737-4742
-
-
Yin, M.1
Bradford, B.U.2
Wheeler, M.D.3
Uesugi, T.4
Froh, M.5
Goyert, S.M.6
Thurman, R.G.7
-
38
-
-
0141755409
-
Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice
-
DOI 10.1053/jhep.2003.50386
-
Sass, G., Soares, M. C., Yamashita, K., Seyfried, S., Zimmermann, W. H., Eschenhagen, T., Kaczmarek, E., Ritter, T., Volk, H. D., and Tiegs, G. (2003) Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice. Hepatology 38, 909-918 (Pubitemid 37221674)
-
(2003)
Hepatology
, vol.38
, Issue.4
, pp. 909-918
-
-
Sass, G.1
Soares, M.C.P.2
Yamashita, K.3
Seyfried, S.4
Zimmermann, W.-H.5
Eschenhagen, T.6
Kaczmarek, E.7
Ritter, T.8
Volk, H.-D.9
Tiegs, G.10
-
39
-
-
33749322086
-
Regulation of peroxisome proliferator-activated receptor-gamma in liver fibrosis
-
DOI 10.1152/ajpgi.00124.2006
-
Yang, L., Chan, C. C., Kwon, O. S., Liu, S., McGhee, J., Stimpson, S. A., Chen, L. Z., Harrington, W. W., Symonds, W. T., and Rockey, D. C. (2006) Regulation of peroxisome proliferator-activated receptor-gamma in liver fibrosis. Am. J. Physiol. Gastrointest Liver Physiol. 291, G902-G911 (Pubitemid 44772017)
-
(2006)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.291
, Issue.5
-
-
Yang, L.1
Chan, C.-C.2
Kwon, O.-S.3
Liu, S.4
McGhee, J.5
Stimpson, S.A.6
Chen, L.Z.7
Harrington, W.W.8
Symonds, W.T.9
Rockey, D.C.10
-
41
-
-
0023277171
-
Analysis of some metabolites of T-2 toxin, diacetoxyscirpenol and deoxynivalenol by thermospray high-performance liquid chromatography-mass spectrometry
-
Voyksner, R. D., Hagler, W. M., Jr., and Swanson, S. P. (1987) Analysis of some metabolites of T-2 toxin, diacetoxyscirpenol and deoxynivalenol, by thermospray high-performance liquid chromatography-mass spectrometry. J. Chromatogr. 394, 183-199 (Pubitemid 17081546)
-
(1987)
Journal of Chromatography
, vol.394
, Issue.1
, pp. 183-199
-
-
Voyksner, R.D.1
Hagler Jr., W.M.2
Swanson, S.P.3
-
42
-
-
0018971344
-
3H-labeled T-2 toxin
-
Yoshizawa, T., Swanson, S. P., and Mirocha, C. J. (1980) T-2 metabolites in the excreta of broiler chickens administered 3H-labeled T-2 toxin. Appl. Environ. Microb. 38, 1172-1177 (Pubitemid 10001985)
-
(1980)
Applied and Environmental Microbiology
, vol.39
, Issue.6
, pp. 1172-1177
-
-
Yoshizawa, T.1
Swanson, S.P.2
Mirocha, C.J.3
-
43
-
-
0346835998
-
Natural occurrence of mycotoxins in foods and feeds: An updated review
-
Pittet, A. (1998) Natural occurrence of mycotoxins in foods and feeds: An updated review. Rev. Med. Vet. 149, 479-492
-
(1998)
Rev. Med. Vet.
, vol.149
, pp. 479-492
-
-
Pittet, A.1
-
44
-
-
61349092282
-
Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture
-
Königs, M., Mulac, D., Schwerdt, G., Gekle, M., and Humpf, H. U. (2009) Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture. Toxicology 258, 106-115
-
(2009)
Toxicology
, vol.258
, pp. 106-115
-
-
Königs, M.1
Mulac, D.2
Schwerdt, G.3
Gekle, M.4
Humpf, H.U.5
-
45
-
-
0036549767
-
Discordant protein and mRNA expression in lung adenocarcinomas
-
Chen, G., Gharib, T. G., Huang, C. C., Taylor, J. M., Misek, D. E., Kardia, S. L., Giordano, T. J., Iannettoni, M. D., Orringer, M. B., Hanash, S. M., and Beer, D. G. (2002) Discordant protein and mRNA expression in lung adenocarcinomas. Mol. Cell Proteomics 1, 304-313
-
(2002)
Mol. Cell Proteomics
, vol.1
, pp. 304-313
-
-
Chen, G.1
Gharib, T.G.2
Huang, C.C.3
Taylor, J.M.4
Misek, D.E.5
Kardia, S.L.6
Giordano, T.J.7
Iannettoni, M.D.8
Orringer, M.B.9
Hanash, S.M.10
Beer, D.G.11
-
46
-
-
0036545614
-
Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae
-
Griffin, T. J., Gygi, S. P., Ideker, T., Rist, B., Eng, J., Hood, L., and Aebersold, R. (2002) Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae. Mol. Cell Proteomics 1, 323-333
-
(2002)
Mol. Cell Proteomics
, vol.1
, pp. 323-333
-
-
Griffin, T.J.1
Gygi, S.P.2
Ideker, T.3
Rist, B.4
Eng, J.5
Hood, L.6
Aebersold, R.7
-
47
-
-
67649979797
-
Oxidative stress induction by T-2 toxin causes DNA damage and triggers apoptosis via caspase pathway in human cervical cancer cells
-
Chaudhari, M., Jayaraj, R., Bhaskar, A. S., and Lakshmana Rao, P. V. (2009) Oxidative stress induction by T-2 toxin causes DNA damage and triggers apoptosis via caspase pathway in human cervical cancer cells. Toxicology 262, 153-161
-
(2009)
Toxicology
, vol.262
, pp. 153-161
-
-
Chaudhari, M.1
Jayaraj, R.2
Bhaskar, A.S.3
Lakshmana Rao, P.V.4
-
48
-
-
77951431126
-
Metabolic pathways of trichothecenes
-
Wu, Q., Dohnal, V., Huang, L., Kuca, K., and Yuan, Z. (2010) Metabolic pathways of trichothecenes. Drug Metab. Rev. 42, 250-267
-
(2010)
Drug Metab. Rev.
, vol.42
, pp. 250-267
-
-
Wu, Q.1
Dohnal, V.2
Huang, L.3
Kuca, K.4
Yuan, Z.5
-
49
-
-
0023237386
-
The cytochrome P-450-dependent hydroxylation of T-2 toxin in various animal species
-
DOI 10.1016/0278-6915(87)90206-7
-
Kobayashi, J., Horikoshi, T., Ryu, J. C., Tashiro, F., Ishii, K., and Ueno, Y. (1987) The cytochrome P-450-dependent hydroxylation of T-2 toxin in various animal species. Food Chem. Toxicol. 25, 539-544 (Pubitemid 17130558)
-
(1987)
Food and Chemical Toxicology
, vol.25
, Issue.7
, pp. 539-544
-
-
Kobayashi, J.1
Horikoshi, T.2
Ryu, J.-C.3
-
50
-
-
0024475302
-
Comparative effect of T-2 toxin and diacetoxyscirpenol on drug metabolizing enzymes in rat tissues
-
DOI 10.1016/0278-6915(89)90158-0
-
Galtier, P., Paulin, F., Eeckhoutte, C., and Larrieu, G. (1989) Comparative effects of T-2 toxin and diacetoxyscirpenol on drug metabolizing enzymes in rat tissues. Food Chem. Toxicol. 27, 215-220 (Pubitemid 19162841)
-
(1989)
Food and Chemical Toxicology
, vol.27
, Issue.4
, pp. 215-220
-
-
Galtier, P.1
Paulin, F.2
Eeckhoutte, C.3
Larrieu, G.4
-
51
-
-
0034530669
-
The effects of T-2 toxin exposure on liver drug metabolizing enzymes in rabbit
-
DOI 10.1080/02652030050207819
-
Guerre, P., Eeckhoutte, C., Burgat, V., and Galtier, P. (2000) The effects of T-2 toxin exposure on liver drug metabolizing enzymes in rabbit. Food Addit. Contam. 17, 1019-1026 (Pubitemid 32014177)
-
(2000)
Food Additives and Contaminants
, vol.17
, Issue.12
, pp. 1019-1026
-
-
Guerre, P.1
Eeckhoutte, C.2
Burgat, V.3
Galtier, P.4
-
52
-
-
41249092361
-
Subclinical doses of T-2 toxin impair acquired immune response and liver cytochrome P450 in pigs
-
Meissonnier, G. M., Laffitte, J., Raymond, I., Benoit, E., Cossalter, A. M., Pinton, P., Bertin, G., Oswald, I. P., and Galtier, P. (2008) Subclinical doses of T-2 toxin impair acquired immune response and liver cytochrome P450 in pigs. Toxicology 247, 46-54
-
(2008)
Toxicology
, vol.247
, pp. 46-54
-
-
Meissonnier, G.M.1
Laffitte, J.2
Raymond, I.3
Benoit, E.4
Cossalter, A.M.5
Pinton, P.6
Bertin, G.7
Oswald, I.P.8
Galtier, P.9
-
53
-
-
0018169571
-
Metabolism of trichothecene mycotoxins II
-
Ohta, M., Matsumoto, H., and Ishii, K. (1978) Metabolism of trichothecene mycotoxins II. J. Biochem. 84, 697-706
-
(1978)
J. Biochem.
, vol.84
, pp. 697-706
-
-
Ohta, M.1
Matsumoto, H.2
Ishii, K.3
-
54
-
-
0032924934
-
Cytochrome P-450 3A4: Regulation and role in drug metabolism
-
Guengerich, F. P. (1999) Cytochrome P-450 3A4: Regulation and role in drug metabolism. Annu. Rev. Pharmacol. Toxicol. 39, 1-17
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 1-17
-
-
Guengerich, F.P.1
-
55
-
-
36049034219
-
Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism
-
DOI 10.1172/JCI33435
-
Van Herwaarden, A. E., Wagenaar, E., Van der Kruijssen, C. M., Van Waterschoot, R. A., Smit, J. W., Song, J. Y., Van der Valk, M. A., Van Tellingen, O., Van der Hoorn, J. W., Rosing, H., Beijnen, J. H., and Schinkel, A. H. (2007) Knockout of cytochrome p450 3a yields new mouse models for understanding xenobiotic metabolism. J. Clin. Invest. 117, 3583-3592 (Pubitemid 350097013)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3583-3592
-
-
Van Herwaarden, A.E.1
Wagenaar, E.2
Van Der, K.C.M.M.3
Van Waterschoot, R.A.B.4
Smit, J.W.5
Song, J.-Y.6
Van Der, V.M.A.7
Van Tellingen, O.8
Van Der, H.J.W.A.9
Rosing, H.10
Beijnen, J.H.11
Schinkel, A.H.12
-
56
-
-
0034811058
-
Cloning and tissue distribution of a novel human cytochrome P450 of the CYP3A subfamily, CYP3A43
-
DOI 10.1006/bbrc.2001.4505
-
Westlind, A., Malmebo, S., Johansson, I., Otter, C., Andersson, T. B., Ingelman-Sundberg, M., and Oscarson, M. (2001) Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43. Biochem. Biophys. Res. Commun. 281, 1349-1355 (Pubitemid 32924568)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.281
, Issue.5
, pp. 1349-1355
-
-
Westlind, A.1
Malmebo, S.2
Johansson, I.3
Otter, C.4
Andersson, T.B.5
Ingelman-Sundberg, M.6
Oscarson, M.7
-
57
-
-
1842589311
-
Cloning CYP2D21 and CYP3A22 cDNAs from liver of miniature pigs
-
DOI 10.1124/dmd.32.4.376
-
Sakuma, T., Shimojima, T., Miwa, K., and Kamataki, T. (2004) Cloning CYP2D21 and CYP3A22 cDNAs from liver of miniature pigs. Drug Metab. Dispos. 32, 376-378 (Pubitemid 38420269)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.4
, pp. 376-378
-
-
Sakuma, T.1
Shimojima, T.2
Miwa, K.3
Kamataki, T.4
-
58
-
-
3442896773
-
Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone
-
DOI 10.1126/science.1099736
-
Williams, P. A., Cosme, J., Vinkovic, D. M., Ward, A., Angove, H. C., Day, P. J., Vonrhein, C., Tickle, I. J., and Jhoti, H. (2004) Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone. Science 305, 683-686 (Pubitemid 39006760)
-
(2004)
Science
, vol.305
, Issue.5684
, pp. 683-686
-
-
Williams, P.A.1
Cosme, J.2
Matak, V.D.3
Ward, A.4
Angove, H.C.5
Day, P.J.6
Vonrhein, C.7
Tickle, I.J.8
Jhoti, H.9
-
59
-
-
0032004672
-
Mapping of porcine genes belonging to two different cytochrome P450 subfamilies
-
DOI 10.1046/j.1365-2052.1998.00225.x
-
Nissen, P. H., Wintero, A. K., and Fredholm, M. (1998) Mapping of porcine genes belonging to two different cytochrome P450 subfamilies. Anim. Genet. 29, 7-11 (Pubitemid 28329398)
-
(1998)
Animal Genetics
, vol.29
, Issue.1
, pp. 7-11
-
-
Nissen, P.H.1
Wintero, A.K.2
Fredholm, M.3
-
60
-
-
0022553141
-
Metabolism of T-2 toxin by rat liver carboxylesterase
-
DOI 10.1016/0006-2952(86)90111-5
-
Johnsen, H., Odden, E., Lie, O., Johnsen, B. A., and Fonnum, F. (1986) Metabolism of T-2 toxin by rat liver carboxylesterase. Biochem. Pharmacol. 35, 1469-1473 (Pubitemid 16038000)
-
(1986)
Biochemical Pharmacology
, vol.35
, Issue.9
, pp. 1469-1473
-
-
Johnsen, H.1
Odden, E.2
Lie, O.3
-
61
-
-
40349098592
-
Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs
-
Hosokawa, M. (2008) Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs. Molecules 13, 412-431
-
(2008)
Molecules
, vol.13
, pp. 412-431
-
-
Hosokawa, M.1
-
62
-
-
0021799235
-
Modification of in vitro metabolism of T-2 toxin by esterase inhibitors
-
Wei, R. D., and Chu, F. S. (1985) Modification of in vitro metabolism of T-2 toxin by esterase inhibitors. Appl. Environ. Microbiol. 50, 115-119
-
(1985)
Appl. Environ. Microbiol.
, vol.50
, pp. 115-119
-
-
Wei, R.D.1
Chu, F.S.2
-
63
-
-
33751227516
-
Degradation of trichothecene mycotoxins by chicken intestinal microbes
-
DOI 10.1016/j.fct.2006.07.028, PII S0278691506002249
-
Young, J. C., Zhou, T., Yu, H., Zhu, H., and Gong, J. (2007) Degradation of trichothecene mycotoxins by chicken intestinal microbes. Food Chem. Toxicol. 45, 136-143 (Pubitemid 44792323)
-
(2007)
Food and Chemical Toxicology
, vol.45
, Issue.1
, pp. 136-143
-
-
Young, J.C.1
Zhou, T.2
Yu, H.3
Zhu, H.4
Gong, J.5
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