T-2 toxin is hydroxylated by chicken CYP3A37

Food and Chemical Toxicology

Volumn 62, Issue , 2013, Pages 622-627

  Yuan, Yiyang ^a   Zhou, Xiaojie ^a,b   Yang, Jiannan ^a   Li, Mei ^a   Qiu, Xinghui ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b Institute of Disinfection and Vector Control   (China)

Author keywords

CYP3A37; Erythromycin N demethylase; Gallus gallus; Hydroxylation; T 2 toxin

Indexed keywords

BACTERIAL ENZYME; CYTOCHROME B5; CYTOCHROME P450 3A; CYTOCHROME P450 3A37; CYTOCHROME P450 3A4; ERYTHROMYCIN; KETOCONAZOLE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; T 2 TOXIN; TRICHOTHECENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CHICKEN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEMETHYLATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RECONSTITUTION; ESCHERICHIA COLI; HYDROXYLATION; IC 50; NONHUMAN; PROTEIN METABOLISM; TOXICOKINETICS; TOXIN SYNTHESIS;

ANIMALIA; AVENA; FUSARIUM; GALLUS GALLUS; HORDEUM; TRITICUM AESTIVUM;

ACETONITRILE; ACN; CID; COLLISION INDUCED DISSOCIATION; CPR; CYP3A37; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; DIMETHYL SULFOXIDE; DMSO; ELECTROSPRAY IONIZATION; ERND; ERYTHROMYCIN N-DEMETHYLASE; ESI; GALLUS GALLUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY; HPLC-Q-TOF/MS; HYDROXYLATION; NADPH; NEO; NEOSOLANIOL; P450; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; T-2 TOXIN;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CHICKENS; CYTOCHROME P-450 CYP3A; CYTOCHROMES B5; ESCHERICHIA COLI; HYDROXYLATION; KETOCONAZOLE; RECOMBINANT PROTEINS; T-2 TOXIN;

EID: 84885732575     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.09.031     Document Type: Article

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