Proteomic changes in chicken primary hepatocytes exposed to T-2 toxin are associated with oxidative stress and mitochondrial enhancement

Proteomics

Volumn 13, Issue 21, 2013, Pages 3175-3188

  Mu, Peiqiang ^a   Xu, Ming ^a   Zhang, Lei ^b   Wu, Kaixin ^a   Wu, Jun ^a   Jiang, Jun ^a   Chen, Qingmei ^a   Wang, Lijuan ^a   Tang, Xianqing ^a   Deng, Yiqun ^a  

^a SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Chicken; Mitochondrial enhancement; Oxidative stress; Proteome; T 2 toxin

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL PROTEIN; MYCOTOXIN; REACTIVE OXYGEN METABOLITE; T 2 TOXIN;

ANIMAL CELL; ARTICLE; CARBOHYDRATE METABOLISM; CELL CYCLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HOMEOSTASIS; LIPID METABOLISM; LIVER CELL; LIVER MITOCHONDRION; LIVER TOXICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MITOCHONDRION; MITOCHONDRION ENHANCEMENT; NEUROLOGIC DISEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEOMICS; STRESS; TRANSLATION REGULATION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

CHICKEN; MITOCHONDRIAL ENHANCEMENT; OXIDATIVE STRESS; PROTEOME; T-2 TOXIN;

ANIMALS; CELLS, CULTURED; CHICK EMBRYO; CHICKENS; HEPATOCYTES; INTRACELLULAR SPACE; MITOCHONDRIA; OXIDATIVE STRESS; PROTEINS; PROTEOME; PROTEOMICS; T-2 TOXIN;

EID: 84887044389     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201300015     Document Type: Article

References (54)

1. Li, Y., Wang, Z., Beier, R. C., Shen, J. et al., T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods. J. Agric. Food Chem. 2011, 59, 3441-3453.
2. Desjardins, A. E., Hohn, T. M., McCormick, S. P., Trichothecene biosynthesis in Fusarium species: chemistry, genetics, and significance. Microbiol. Rev. 1993, 57, 595-604.
3. Kalantari, H., Moosavi, M. Review on T-2 toxin. JJNPP 2010, 5, 26-38.
4. Paterson, R. R., Lima, N., Toxicology of mycotoxins. EXS 2010, 100, 31-63.
5. Adejumo, T. O., Hettwer, U., Karlovsky, P., Occurrence of Fusarium species and trichothecenes in Nigerian maize. Int. J. Food Microbiol. 2007, 116, 350-357.
6. Curtui, V., Usleber, E., Dietrich, R., Lepschy, J., Martlbauer, E., A survey on the occurrence of mycotoxins in wheat and maize from western Romania. Mycopathologia 1998, 143, 97-103.
7. Bennett, J. W., Klich, M., Mycotoxins. Clin. Microbiol. Rev. 2003, 16, 497-516.
8. Sokolovic, M., Garaj-Vrhovac, V., Simpraga, B., T-2 toxin: incidence and toxicity in poultry. Arh. Hig. Rada Toksikol. 2008, 59, 43-52.
9. Schollenberger, M., Muller, H. M., Rufle, M., Suchy, S. et al., Natural occurrence of 16 Fusarium toxins in grains and feedstuffs of plant origin from Germany. Mycopathologia 2006, 161, 43-52.
10. Tobias, S., Rajic, I., Vanyi, A., Effect of T-2 toxin on egg production and hatchability in laying hens. Acta Vet. Hung. 1992, 40, 47-54.
11. Diaz, G. J., Squires, E. J., Julian, R. J., Boermans, H. J., Individual and combined effects of T-2 toxin and DAS in laying hens. Br. Poult. Sci. 1994, 35, 393-405.
12. Wyatt, R. D., Doerr, J. A., Hamilton, P. B., Burmeister, H. R., Egg production, shell thickness, and other physiological parameters of laying hens affected by T-2 toxin. Appl. Microbiol. 1975, 29, 641-645.
13. Lee, J. T., Jessen, K. A., Beltran, R., Starkl, V. et al., Effects of mycotoxin-contaminated diets and deactivating compound in laying hens: 2. Effects on white shell egg quality and characteristics. Poult. Sci. 2012, 91, 2096-2104.
14. Wyatt, R. D., Hamilton, P. B., Burmeister, H. R., Altered feathering of chicks caused by T-2 toxin. Poult. Sci. 1975, 54, 1042-1045.
15. Pande, V. V., Kurkure, N. V., Bhandarkar, A. G., Effect of T-2 toxin on growth, performance and haematobiochemical alterations in broilers. Indian J. Exp. Biol. 2006, 44, 86-88.
16. Frankic, T., Pajk, T., Rezar, V., Levart, A., Salobir, J., The role of dietary nucleotides in reduction of DNA damage induced by T-2 toxin and deoxynivalenol in chicken leukocytes. Food Chem. Toxicol. 2006, 44, 1838-1844.
17. He, S. J., Hou, J. F., Dai, Y. Y., Zhou, Z. L., Deng, Y. F., N-acetyl-cysteine protects chicken growth plate chondrocytes from T-2 toxin-induced oxidative stress. J. Appl. Toxicol. 2011, 32, 980-985.
18. Dvorska, J. E., Pappas, A. C., Karadas, F., Speake, B. K., Surai, P. F., Protective effect of modified glucomannans and organic selenium against antioxidant depletion in the chicken liver due to T-2 toxin-contaminated feed consumption. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2007, 145, 582-587.
19. Huang, P., Akagawa, K., Yokoyama, Y., Nohara, K. et al., T-2 toxin initially activates caspase-2 and induces apoptosis in U937 cells. Toxicol. Lett. 2007, 170, 1-10.
20. Bouaziz, C., Abid-Essefi, S., Bouslimi, A., El Golli, E., Bacha, H., Cytotoxicity and related effects of T-2 toxin on cultured Vero cells. Toxicon 2006, 48, 343-352.
21. Bouaziz, C., Sharaf El Dein, O., El Golli, E., Abid-Essefi, S. et al., Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells. Toxicology 2008, 254, 19-28.
22. Shinozuka, J., Suzuki, M., Noguchi, N., Sugimoto, T. et al., T-2 toxin-induced apoptosis in hematopoietic tissues of mice. Toxicol. Pathol. 1998, 26, 674-681.
23. Albarenque, S. M., Shinozuka, J., Iwamoto, S., Nakayama, H., Doi, K., T-2 toxin-induced acute skin lesions in Wistar-derived hypotrichotic WBN/ILA-Ht rats. Histol. Histopathol. 1999, 14, 337-342.
24. Grizzle, J. M., Kersten, D. B., McCracken, M. D., Houston, A. E., Saxton, A. M., Determination of the acute 50% lethal dose T-2 toxin in adult bobwhite quail: additional studies on the effect of T-2 mycotoxin on blood chemistry and the morphology of internal organs. Avian Dis. 2004, 48, 392-399.
25. Sehata, S., Kiyosawa, N., Makino, T., Atsumi, F. et al., Morphological and microarray analysis of T-2 toxin-induced rat fetal brain lesion. Food Chem. Toxicol. 2004, 42, 1727-1736.
26. Dugyala, R. R., Kim, Y. W., Sharma, R. P., Effects of aflatoxin B1 and T-2 toxin on the granulocyte-macrophage progenitor cells in mouse bone marrow cultures. Immunopharmacology 1994, 27, 57-65.
27. Lautraite, S., Parent-Massin, D., Rio, B., Hoellinger, H., Comparison of toxicity induced by T-2 toxin on human and rat granulo-monocytic progenitors with an in vitro model. Hum. Exp. Toxicol. 1995, 14, 672-678.
28. Parent-Massin, D., Haematotoxicity of trichothecenes. Toxicol. Lett. 2004, 153, 75-81.
29. Lafarge-Frayssinet, C., Decloitre, F., Mousset, S., Martin, M., Frayssinet, C., Induction of DNA single-strand breaks by T-2 toxin, a trichothecene metabolite of Fusarium: effect on lymphoid organs and liver. Muta. Res. /Genet. Toxicol. 1981, 88, 115-123.
30. Li, M., Harkema, J. R., Islam, Z., Cuff, C. F., Pestka, J. J., T-2 toxin impairs murine immune response to respiratory reovirus and exacerbates viral bronchiolitis. Toxicol. Appl. Pharmacol. 2006, 217, 76-85.
31. Bunner, D. L., Morris, E. R., Alteration of multiple cell membrane functions in L-6 myoblasts by T-2 toxin: an important mechanism of action. Toxicol. Appl. Pharmacol. 1988, 92, 113-121.
32. Kamalavenkatesh, P., Vairamuthu, S., Balachandran, C., Manohar, B. M., Raj, G. D., Immunopathological effect of the mycotoxins cyclopiazonic acid and T-2 toxin on broiler chicken. Mycopathologia 2005, 159, 273-279.
33. Hymery, N., Sibiril, Y., Parent-Massin, D., In vitro effects of trichothecenes on human dendritic cells. Toxicol. In Vitro 2006, 20, 899-909.
34. Wang, J., Jiang, J., Zhang, H., Cai, H. et al., Integrated transcriptional and proteomic analysis with in vitro biochemical assay reveal the important role of CYP3A46 in T-2 toxin hydroxylation in porcine primary hepatocytes. Mol. Cell. Proteomics 2011, 10, M111. 008748.
35. Liu, J., Ouyang, M., Jiang, J., Mu, P. et al., Mequindox induced cellular DNA damage via generation of reactive oxygen species. Mutat. Res. 2012, 741, 70-75.
36. Hamer, M. J., Dickson, A. J., Control of glycolysis in cultured chick embryo hepatocytes. Fructose 2, 6-bisphosphate content and phosphofructokinase-1 activity are stimulated by insulin and epidermal growth factor. Biochem. J. 1990, 269, 685-690.
37. Mosmann, T., Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63.
38. Yan, J. X., Wait, R., Berkelman, T., Harry, R. A. et al., A modified silver staining protocol for visualization of proteins compatible with matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry. Electrophoresis 2000, 21, 3666-3672.
39. Livak, K. J., Schmittgen, T. D., Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25, 402-408.
40. Olive, P. L., Wlodek, D., Durand, R. E., Banath, J. P., Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp. Cell Res. 1992, 198, 259-267.
41. Parra, V., Eisner, V., Chiong, M., Criollo, A. et al., Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovasc. Res. 2008, 77, 387-397.
42. Richter, C., Schweizer, M., Cossarizza, A., Franceschi, C., Control of apoptosis by the cellular ATP level. FEBS Lett. 1996, 378, 107-110.
43. Zamaraeva, M. V., Sabirov, R. Z., Maeno, E., Ando-Akatsuka, Y. et al., Cells die with increased cytosolic ATP during apoptosis: a bioluminescence study with intracellular luciferase. Cell Death Differ. 2005, 12, 1390-1397.
44. Wu, J., Jing, L., Yuan, H., Peng, S. Q., T-2 toxin induces apoptosis in ovarian granulosa cells of rats through reactive oxygen species-mediated mitochondrial pathway. Toxicol. Lett. 2011, 202, 168-177.
45. Rakkestad, K. E., Skaar, I., Ansteinsson, V. E., Solhaug, A. et al., DNA damage and DNA damage responses in THP-1 monocytes after exposure to spores of either Stachybotrys chartarum or Aspergillus versicolor or to T-2 toxin. Toxicol. Sci. 2010, 115, 140-155.
46. Shifrin, V. I., Anderson, P., Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase and induces apoptosis. J. Bio. Chem. 1999, 274, 13985-13992.
47. Smeitink, J., van den Heuvel, L., Human mitochondrial complex I in health and disease. Am. J. Hum. Genet. 1999, 64, 1505-1510.
48. Navarro, A., Boveris, A., Brain mitochondrial dysfunction and oxidative damage in Parkinson's disease. J. Bioenerg. Biomembr. 2009, 41, 517-521.
49. Morris, E. M., Rector, R. S., Thyfault, J. P., Ibdah, J. A., Mitochondria and redox signaling in steatohepatitis. Antioxid. Redox Signal. 2011, 15, 485-504.
50. Brookes, P. S., Yoon, Y., Robotham, J. L., Anders, M. W., Sheu, S. S., Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am .J. Physiol. 2004, 287, C817-833.
51. Lee, H. C., Yin, P. H., Lu, C. Y., Chi, C. W., Wei, Y. H., Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells. Biochem. J. 2000, 348, 425-432.
52. Wallace, D. C., Fan, W., Procaccio, V., Mitochondrial energetics and therapeutics. Ann. Rre. Pathol. 2010, 5, 297-348.
53. + oxidation-reduction state. Biochem. J. 2002, 368, 545-553.
54. Pessayre, D., Fromenty, B., Mansouri, A., Mitochondrial injury in steatohepatitis. Eur. J. Gastroenterol. Hepatol. 2004, 16, 1095-1105.