Oxidative stress induction by T-2 toxin causes DNA damage and triggers apoptosis via caspase pathway in human cervical cancer cells

Toxicology

Volumn 262, Issue 2, 2009, Pages 153-161

  Chaudhari, Manjari ^a   Jayaraj, R ^a   Bhaskar, A S B ^a   Lakshmana Rao, P V ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

Apoptosis; DNA damage; DNA diffusion assay; Oxidative stress; T 2 toxin

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 7; CASPASE 9; CYTOCHROME C; GLUTATHIONE; LACTATE DEHYDROGENASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SINGLE STRANDED DNA; T 2 TOXIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; HELA CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSACTIVATION; UTERINE CERVIX CANCER;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CELL SURVIVAL; DNA DAMAGE; DNA, NEOPLASM; FEMALE; GLUTATHIONE; HELA CELLS; HUMANS; LIPID PEROXIDATION; MALONDIALDEHYDE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; T-2 TOXIN; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

ANIMALIA;

EID: 67649979797     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.06.002     Document Type: Article

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