T-2 toxin induces apoptosis in ovarian granulosa cells of rats through reactive oxygen species-mediated mitochondrial pathway

Toxicology Letters

Volumn 202, Issue 3, 2011, Pages 168-177

  Wu, Jing ^a,b   Jing, Li ^a   Yuan, Hui ^b   Peng, Shuang qing ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b HUNAN AGRICULTURAL UNIVERSITY   (China)

Author keywords

Apoptosis; Granulosa cells; Mitochondrial; Reactive oxygen species; T 2 toxin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 3; CASPASE 9; DIHYDRORHODAMINE 123; MYCOTOXIN; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; T 2 TOXIN; TROLOX C;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; CYTOTOXICITY; FLUOROMETRY; GRANULOSA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCTIVE TOXICITY; UPREGULATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL SURVIVAL; CELLS, CULTURED; FEMALE; FORMAZANS; GENE EXPRESSION; GRANULOSA CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; T-2 TOXIN; TETRAZOLIUM SALTS;

RATTUS;

EID: 79954580538     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.01.029     Document Type: Article

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