메뉴 건너뛰기




Volumn 2, Issue , 2013, Pages 947-962

Pharmacology of Polyphenols in Cardiac Remodeling: Potential Biological Mechanisms

Author keywords

Cardiac fibrosis; Cardiac hypertrophy; Cardiac remodeling; Heart failure; Pharmacology; Polyphenol

Indexed keywords


EID: 84902568621     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-398456-2.00073-6     Document Type: Chapter
Times cited : (4)

References (169)
  • 1
    • 13344259975 scopus 로고    scopus 로고
    • Ventricular remodeling
    • Maisch B. Ventricular remodeling. Cardiology 1996, 87(Suppl. 1):2-10.
    • (1996) Cardiology , vol.87 , Issue.SUPPL. 1 , pp. 2-10
    • Maisch, B.1
  • 2
    • 0034162004 scopus 로고    scopus 로고
    • Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an international forum on cardiac remodeling
    • Cohn J.N., Ferrari R., Sharpe N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an international forum on cardiac remodeling. J Am Coll Cardiol 2000, 35(3):569-582.
    • (2000) J Am Coll Cardiol , vol.35 , Issue.3 , pp. 569-582
    • Cohn, J.N.1    Ferrari, R.2    Sharpe, N.3
  • 3
    • 78650710691 scopus 로고    scopus 로고
    • Molecular pathways underlying cardiac remodeling during pathophysiological stimulation
    • Kehat I., Molkentin J.D. Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. Circulation 2010, 122(25):2727-2735.
    • (2010) Circulation , vol.122 , Issue.25 , pp. 2727-2735
    • Kehat, I.1    Molkentin, J.D.2
  • 4
    • 0042171678 scopus 로고    scopus 로고
    • Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies
    • Takano H., Hasegawa H., Nagai T., Komuro I. Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies. Intern Med 2003, 42(6):465-469.
    • (2003) Intern Med , vol.42 , Issue.6 , pp. 465-469
    • Takano, H.1    Hasegawa, H.2    Nagai, T.3    Komuro, I.4
  • 5
    • 31444448021 scopus 로고    scopus 로고
    • Controversies in ventricular remodelling
    • Opie L.H., Commerford P.J., Gersh B.J., Pfeffer M.A. Controversies in ventricular remodelling. Lancet 2006, 367(9507):356-367.
    • (2006) Lancet , vol.367 , Issue.9507 , pp. 356-367
    • Opie, L.H.1    Commerford, P.J.2    Gersh, B.J.3    Pfeffer, M.A.4
  • 7
    • 34648843625 scopus 로고    scopus 로고
    • Mechanisms of cardiac fibrosis in hypertension
    • Diez J. Mechanisms of cardiac fibrosis in hypertension. J Clin Hypertens (Greenwich) 2007, 9(7):546-550.
    • (2007) J Clin Hypertens (Greenwich) , vol.9 , Issue.7 , pp. 546-550
    • Diez, J.1
  • 8
    • 0032996757 scopus 로고    scopus 로고
    • Cardiac fibrosis and inflammation: interaction with hemodynamic and hormonal factors
    • Nicoletti A., Michel J.B. Cardiac fibrosis and inflammation: interaction with hemodynamic and hormonal factors. Cardiovasc Res 1999, 41(3):532-543.
    • (1999) Cardiovasc Res , vol.41 , Issue.3 , pp. 532-543
    • Nicoletti, A.1    Michel, J.B.2
  • 9
    • 78650121847 scopus 로고    scopus 로고
    • Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies
    • Bernardo B.C., Weeks K.L., Pretorius L., McMullen J.R. Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies. Pharmacol Ther 2010, 128(1):191-227.
    • (2010) Pharmacol Ther , vol.128 , Issue.1 , pp. 191-227
    • Bernardo, B.C.1    Weeks, K.L.2    Pretorius, L.3    McMullen, J.R.4
  • 10
    • 0034640357 scopus 로고    scopus 로고
    • Altered patterns of gene expression in response to myocardial infarction
    • Stanton L.W., Garrard L.J., Damm D., Garrick B.L., Lam A., Kapoun A.M., et al. Altered patterns of gene expression in response to myocardial infarction. Circ Res 2000, 86(9):939-945.
    • (2000) Circ Res , vol.86 , Issue.9 , pp. 939-945
    • Stanton, L.W.1    Garrard, L.J.2    Damm, D.3    Garrick, B.L.4    Lam, A.5    Kapoun, A.M.6
  • 11
    • 13844251877 scopus 로고    scopus 로고
    • Cardiac remodeling and failure: from molecules to man (Part I)
    • Fedak P.W., Verma S., Weisel R.D., Li R.K. Cardiac remodeling and failure: from molecules to man (Part I). Cardiovasc Pathol 2005, 14(1):1-11.
    • (2005) Cardiovasc Pathol , vol.14 , Issue.1 , pp. 1-11
    • Fedak, P.W.1    Verma, S.2    Weisel, R.D.3    Li, R.K.4
  • 12
    • 0033621141 scopus 로고    scopus 로고
    • Mechanisms and models in heart failure: a combinatorial approach
    • Mann D.L. Mechanisms and models in heart failure: a combinatorial approach. Circulation 1999, 100(9):999-1008.
    • (1999) Circulation , vol.100 , Issue.9 , pp. 999-1008
    • Mann, D.L.1
  • 13
    • 77649270132 scopus 로고    scopus 로고
    • Extracellular matrix turnover and signaling during cardiac remodeling following MI: causes and consequences
    • Zamilpa R., Lindsey M.L. Extracellular matrix turnover and signaling during cardiac remodeling following MI: causes and consequences. J Mol Cell Cardiol 2010, 48(3):558-563.
    • (2010) J Mol Cell Cardiol , vol.48 , Issue.3 , pp. 558-563
    • Zamilpa, R.1    Lindsey, M.L.2
  • 14
    • 34249679213 scopus 로고    scopus 로고
    • Epigallocatechin-3 gallate prevents cardiac hypertrophy induced by pressure overload in rats
    • Hao J., Kim C.H., Ha T.S., Ahn H.Y. Epigallocatechin-3 gallate prevents cardiac hypertrophy induced by pressure overload in rats. J Vet Sci 2007, 8(2):121-129.
    • (2007) J Vet Sci , vol.8 , Issue.2 , pp. 121-129
    • Hao, J.1    Kim, C.H.2    Ha, T.S.3    Ahn, H.Y.4
  • 15
    • 63149125593 scopus 로고    scopus 로고
    • EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy
    • Sheng R., Gu Z.L., Xie M.L., Zhou W.X., Guo C.Y. EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy. Planta Med 2009, 75(2):113-120.
    • (2009) Planta Med , vol.75 , Issue.2 , pp. 113-120
    • Sheng, R.1    Gu, Z.L.2    Xie, M.L.3    Zhou, W.X.4    Guo, C.Y.5
  • 16
    • 33746671438 scopus 로고    scopus 로고
    • Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways
    • Li H.L., Huang Y., Zhang C.N., Liu G., Wei Y.S., Wang A.B., et al. Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radic Biol Med 2006, 40(10):1756-1775.
    • (2006) Free Radic Biol Med , vol.40 , Issue.10 , pp. 1756-1775
    • Li, H.L.1    Huang, Y.2    Zhang, C.N.3    Liu, G.4    Wei, Y.S.5    Wang, A.B.6
  • 17
    • 78650006001 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate attenuates cardiac hypertrophy partly via MAPKs signals in hypertensive rats
    • Chen D.D., Dong Y.G., Liu D., He J.G. Epigallocatechin-3-gallate attenuates cardiac hypertrophy partly via MAPKs signals in hypertensive rats. Clin Exp Pharmacol Physiol 2009, 36(9):926-932.
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , Issue.9 , pp. 926-932
    • Chen, D.D.1    Dong, Y.G.2    Liu, D.3    He, J.G.4
  • 18
    • 33846512151 scopus 로고    scopus 로고
    • EGCG inhibits cardiomyocyte apoptosis in pressure overload-induced cardiac hypertrophy and protects cardiomyocytes from oxidative stress in rats
    • Sheng R., Gu Z.L., Xie M.L., Zhou W.X., Guo C.Y. EGCG inhibits cardiomyocyte apoptosis in pressure overload-induced cardiac hypertrophy and protects cardiomyocytes from oxidative stress in rats. Acta Pharmacol Sin 2007, 28(2):191-201.
    • (2007) Acta Pharmacol Sin , vol.28 , Issue.2 , pp. 191-201
    • Sheng, R.1    Gu, Z.L.2    Xie, M.L.3    Zhou, W.X.4    Guo, C.Y.5
  • 19
    • 77953308194 scopus 로고    scopus 로고
    • Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion
    • Yamazaki K.G., Taub P.R., Barraza-Hidalgo M., Rivas M.M., Zambon A.C., Ceballos G., et al. Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion. J Am Coll Cardiol 2010, 55(25):2869-2876.
    • (2010) J Am Coll Cardiol , vol.55 , Issue.25 , pp. 2869-2876
    • Yamazaki, K.G.1    Taub, P.R.2    Barraza-Hidalgo, M.3    Rivas, M.M.4    Zambon, A.C.5    Ceballos, G.6
  • 20
    • 33846365020 scopus 로고    scopus 로고
    • Tea catechins attenuate chronic ventricular remodeling after myocardial ischemia in rats
    • Suzuki J., Ogawa M., Maejima Y., Isobe K., Tanaka H., Sagesaka Y.M., et al. Tea catechins attenuate chronic ventricular remodeling after myocardial ischemia in rats. J Mol Cell Cardiol 2007, 42(2):432-440.
    • (2007) J Mol Cell Cardiol , vol.42 , Issue.2 , pp. 432-440
    • Suzuki, J.1    Ogawa, M.2    Maejima, Y.3    Isobe, K.4    Tanaka, H.5    Sagesaka, Y.M.6
  • 21
    • 58849163229 scopus 로고    scopus 로고
    • Preventive effects of nutritional doses of polyphenolic molecules on cardiac fibrosis associated with metabolic syndrome: involvement of osteopontin and oxidative stress
    • Sutra T., Oiry C., Azay-Milhau J., Youl E., Magous R., Teissedre P.L., et al. Preventive effects of nutritional doses of polyphenolic molecules on cardiac fibrosis associated with metabolic syndrome: involvement of osteopontin and oxidative stress. J Agric Food Chem 2008, 56(24):11683-11687.
    • (2008) J Agric Food Chem , vol.56 , Issue.24 , pp. 11683-11687
    • Sutra, T.1    Oiry, C.2    Azay-Milhau, J.3    Youl, E.4    Magous, R.5    Teissedre, P.L.6
  • 22
    • 80051672207 scopus 로고    scopus 로고
    • Green tea polyphenols avert chronic inflammation-induced myocardial fibrosis of female rats
    • Shen C.L., Samathanam C., Tatum O.L., Graham S., Tubb C., Cao J.J., et al. Green tea polyphenols avert chronic inflammation-induced myocardial fibrosis of female rats. Inflamm Res 2011, 60(7):665-672.
    • (2011) Inflamm Res , vol.60 , Issue.7 , pp. 665-672
    • Shen, C.L.1    Samathanam, C.2    Tatum, O.L.3    Graham, S.4    Tubb, C.5    Cao, J.J.6
  • 23
    • 77955227051 scopus 로고    scopus 로고
    • Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis
    • Mereles D., Buss S.J., Hardt S.E., Hunstein W., Katus H.A. Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis. Clin Res Cardiol 2010, 99(8):483-490.
    • (2010) Clin Res Cardiol , vol.99 , Issue.8 , pp. 483-490
    • Mereles, D.1    Buss, S.J.2    Hardt, S.E.3    Hunstein, W.4    Katus, H.A.5
  • 24
    • 68849091992 scopus 로고    scopus 로고
    • Quercetin prevents cardiac hypertrophy induced by pressure overload in rats
    • Han J.J., Hao J., Kim C.H., Hong J.S., Ahn H.Y., Lee Y.S. Quercetin prevents cardiac hypertrophy induced by pressure overload in rats. J Vet Med Sci 2009, 71(6):737-743.
    • (2009) J Vet Med Sci , vol.71 , Issue.6 , pp. 737-743
    • Han, J.J.1    Hao, J.2    Kim, C.H.3    Hong, J.S.4    Ahn, H.Y.5    Lee, Y.S.6
  • 25
    • 33748139308 scopus 로고    scopus 로고
    • Quercetin-supplemented diets lower blood pressure and attenuate cardiac hypertrophy in rats with aortic constriction
    • Jalili T., Carlstrom J., Kim S., Freeman D., Jin H., Wu T.C., et al. Quercetin-supplemented diets lower blood pressure and attenuate cardiac hypertrophy in rats with aortic constriction. J Cardiovasc Pharmacol 2006, 47(4):531-541.
    • (2006) J Cardiovasc Pharmacol , vol.47 , Issue.4 , pp. 531-541
    • Jalili, T.1    Carlstrom, J.2    Kim, S.3    Freeman, D.4    Jin, H.5    Wu, T.C.6
  • 26
    • 1942474582 scopus 로고    scopus 로고
    • Effects of chronic quercetin treatment on antioxidant defence system and oxidative status of deoxycorticosterone acetate-salt-hypertensive rats
    • Galisteo M., Garcia-Saura M.F., Jimenez R., Villar I.C., Zarzuelo A., Vargas F., et al. Effects of chronic quercetin treatment on antioxidant defence system and oxidative status of deoxycorticosterone acetate-salt-hypertensive rats. Mol Cell Biochem 2004, 259(1-2):91-99.
    • (2004) Mol Cell Biochem , vol.259 , Issue.1-2 , pp. 91-99
    • Galisteo, M.1    Garcia-Saura, M.F.2    Jimenez, R.3    Villar, I.C.4    Zarzuelo, A.5    Vargas, F.6
  • 27
    • 33947175585 scopus 로고    scopus 로고
    • A quercetin supplemented diet does not prevent cardiovascular complications in spontaneously hypertensive rats
    • Carlstrom J., Symons J.D., Wu T.C., Bruno R.S., Litwin S.E., Jalili T. A quercetin supplemented diet does not prevent cardiovascular complications in spontaneously hypertensive rats. J Nutr 2007, 137(3):628-633.
    • (2007) J Nutr , vol.137 , Issue.3 , pp. 628-633
    • Carlstrom, J.1    Symons, J.D.2    Wu, T.C.3    Bruno, R.S.4    Litwin, S.E.5    Jalili, T.6
  • 29
    • 85047684223 scopus 로고    scopus 로고
    • Cardioprotective actions of two bioflavonoids, quercetin and rutin, in experimental myocardial infarction in both normal and streptozotocin-induced type I diabetic rats
    • Annapurna A., Reddy C.S., Akondi R.B., Rao S.R. Cardioprotective actions of two bioflavonoids, quercetin and rutin, in experimental myocardial infarction in both normal and streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 2009, 61(10):1365-1374.
    • (2009) J Pharm Pharmacol , vol.61 , Issue.10 , pp. 1365-1374
    • Annapurna, A.1    Reddy, C.S.2    Akondi, R.B.3    Rao, S.R.4
  • 30
    • 1842715068 scopus 로고    scopus 로고
    • Inhibitory effect of quercetin on cultured neonatal rat cardiomyocytes hypertrophy induced by angiotensin
    • Qin T.C., Chen L., Yu L.X., Gu Z.L. Inhibitory effect of quercetin on cultured neonatal rat cardiomyocytes hypertrophy induced by angiotensin. Acta Pharmacol Sin 2001, 22(12):1103-1106.
    • (2001) Acta Pharmacol Sin , vol.22 , Issue.12 , pp. 1103-1106
    • Qin, T.C.1    Chen, L.2    Yu, L.X.3    Gu, Z.L.4
  • 31
    • 84863027430 scopus 로고    scopus 로고
    • Quercetin offers cardioprotection against progression of experimental autoimmune myocarditis by suppression of oxidative and endoplasmic reticulum stress via endothelin-1/MAPK signalling
    • Arumugam S., Thandavarayan R.A., Arozal W., Sari F.R., Giridharan V.V., Soetikno V., et al. Quercetin offers cardioprotection against progression of experimental autoimmune myocarditis by suppression of oxidative and endoplasmic reticulum stress via endothelin-1/MAPK signalling. Free Radic Res 2012, 46(2):154-163.
    • (2012) Free Radic Res , vol.46 , Issue.2 , pp. 154-163
    • Arumugam, S.1    Thandavarayan, R.A.2    Arozal, W.3    Sari, F.R.4    Giridharan, V.V.5    Soetikno, V.6
  • 32
    • 77951435651 scopus 로고    scopus 로고
    • Resveratrol arrests and regresses the development of pressure overload- but not volume overload-induced cardiac hypertrophy in rats
    • Wojciechowski P., Juric D., Louis X.L., Thandapilly S.J., Yu L., Taylor C., et al. Resveratrol arrests and regresses the development of pressure overload- but not volume overload-induced cardiac hypertrophy in rats. J Nutr 2010, 140(5):962-968.
    • (2010) J Nutr , vol.140 , Issue.5 , pp. 962-968
    • Wojciechowski, P.1    Juric, D.2    Louis, X.L.3    Thandapilly, S.J.4    Yu, L.5    Taylor, C.6
  • 33
    • 77952837883 scopus 로고    scopus 로고
    • Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes
    • Biala A., Tauriainen E., Siltanen A., Shi J., Merasto S., Louhelainen M., et al. Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes. Blood Press 2010, 19(3):196-205.
    • (2010) Blood Press , vol.19 , Issue.3 , pp. 196-205
    • Biala, A.1    Tauriainen, E.2    Siltanen, A.3    Shi, J.4    Merasto, S.5    Louhelainen, M.6
  • 34
    • 68249153548 scopus 로고    scopus 로고
    • Resveratrol attenuates angiotensin II-induced interleukin-6 expression and perivascular fibrosis
    • Inanaga K., Ichiki T., Matsuura H., Miyazaki R., Hashimoto T., Takeda K., et al. Resveratrol attenuates angiotensin II-induced interleukin-6 expression and perivascular fibrosis. Hypertens Res 2009, 32(6):466-471.
    • (2009) Hypertens Res , vol.32 , Issue.6 , pp. 466-471
    • Inanaga, K.1    Ichiki, T.2    Matsuura, H.3    Miyazaki, R.4    Hashimoto, T.5    Takeda, K.6
  • 35
    • 84859524897 scopus 로고    scopus 로고
    • The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice
    • S1-6
    • Qin F., Siwik D.A., Luptak I., Hou X., Wang L., Higuchi A., et al. The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation 2012, 125(14):1757-1764. S1-6.
    • (2012) Circulation , vol.125 , Issue.14 , pp. 1757-1764
    • Qin, F.1    Siwik, D.A.2    Luptak, I.3    Hou, X.4    Wang, L.5    Higuchi, A.6
  • 36
    • 80054736902 scopus 로고    scopus 로고
    • Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure
    • Rimbaud S., Ruiz M., Piquereau J., Mateo P., Fortin D., Veksler V., et al. Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure. PLoS One 2011, 6(10):e26391.
    • (2011) PLoS One , vol.6 , Issue.10
    • Rimbaud, S.1    Ruiz, M.2    Piquereau, J.3    Mateo, P.4    Fortin, D.5    Veksler, V.6
  • 37
    • 80052051692 scopus 로고    scopus 로고
    • Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway
    • Thandapilly S.J., Louis X.L., Yang T., Stringer D.M., Yu L., Zhang S., et al. Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway. Eur J Pharmacol 2011, 668(1-2):217-224.
    • (2011) Eur J Pharmacol , vol.668 , Issue.1-2 , pp. 217-224
    • Thandapilly, S.J.1    Louis, X.L.2    Yang, T.3    Stringer, D.M.4    Yu, L.5    Zhang, S.6
  • 38
    • 49549114451 scopus 로고    scopus 로고
    • Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats
    • Lin J.F., Lin S.M., Chih C.L., Nien M.W., Su H.H., Hu B.R., et al. Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats. Life Sci 2008, 83(9-10):313-317.
    • (2008) Life Sci , vol.83 , Issue.9-10 , pp. 313-317
    • Lin, J.F.1    Lin, S.M.2    Chih, C.L.3    Nien, M.W.4    Su, H.H.5    Hu, B.R.6
  • 40
  • 41
    • 34249103889 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferation of cultured rat cardiac fibroblasts: correlated with NO-cGMP signaling pathway
    • Wang S., Wang X., Yan J., Xie X., Fan F., Zhou X., et al. Resveratrol inhibits proliferation of cultured rat cardiac fibroblasts: correlated with NO-cGMP signaling pathway. Eur J Pharmacol 2007, 567(1-2):26-35.
    • (2007) Eur J Pharmacol , vol.567 , Issue.1-2 , pp. 26-35
    • Wang, S.1    Wang, X.2    Yan, J.3    Xie, X.4    Fan, F.5    Zhou, X.6
  • 42
    • 67349156421 scopus 로고    scopus 로고
    • Alcohol-free red wine inhibits isoproterenol-induced cardiac remodeling in rats by the regulation of Akt1 and protein kinase C alpha/beta II
    • Palfi A., Bartha E., Copf L., Mark L., Gallyas F., Veres B., et al. Alcohol-free red wine inhibits isoproterenol-induced cardiac remodeling in rats by the regulation of Akt1 and protein kinase C alpha/beta II. J Nutr Biochem 2009, 20(6):418-425.
    • (2009) J Nutr Biochem , vol.20 , Issue.6 , pp. 418-425
    • Palfi, A.1    Bartha, E.2    Copf, L.3    Mark, L.4    Gallyas, F.5    Veres, B.6
  • 44
    • 79953800506 scopus 로고    scopus 로고
    • A novel anti-fibrotic agent, baicalein, for the treatment of myocardial fibrosis in spontaneously hypertensive rats
    • Kong E.K., Yu S., Sanderson J.E., Chen K.B., Huang Y., Yu C.M. A novel anti-fibrotic agent, baicalein, for the treatment of myocardial fibrosis in spontaneously hypertensive rats. Eur J Pharmacol 2011, 658(2-3):175-181.
    • (2011) Eur J Pharmacol , vol.658 , Issue.2-3 , pp. 175-181
    • Kong, E.K.1    Yu, S.2    Sanderson, J.E.3    Chen, K.B.4    Huang, Y.5    Yu, C.M.6
  • 45
    • 83555174332 scopus 로고    scopus 로고
    • Gastrodin protects against cardiac hypertrophy and fibrosis
    • Shu C., Chen C., Zhang D.P., Guo H., Zhou H., Zong J., et al. Gastrodin protects against cardiac hypertrophy and fibrosis. Mol Cell Biochem 2012, 359(1-2):9-16.
    • (2012) Mol Cell Biochem , vol.359 , Issue.1-2 , pp. 9-16
    • Shu, C.1    Chen, C.2    Zhang, D.P.3    Guo, H.4    Zhou, H.5    Zong, J.6
  • 46
    • 77951700259 scopus 로고    scopus 로고
    • Breviscapine protects against cardiac hypertrophy through blocking PKC-alpha-dependent signaling
    • Yan L., Huang H., Tang Q.Z., Zhu L.H., Wang L., Liu C., et al. Breviscapine protects against cardiac hypertrophy through blocking PKC-alpha-dependent signaling. J Cell Biochem 2010, 109(6):1158-1171.
    • (2010) J Cell Biochem , vol.109 , Issue.6 , pp. 1158-1171
    • Yan, L.1    Huang, H.2    Tang, Q.Z.3    Zhu, L.H.4    Wang, L.5    Liu, C.6
  • 47
    • 68349085537 scopus 로고    scopus 로고
    • Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway
    • Wang M., Zhang W.B., Zhu J.H., Fu G.S., Zhou B.Q. Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway. Acta Pharmacol Sin 2009, 30(8):1081-1091.
    • (2009) Acta Pharmacol Sin , vol.30 , Issue.8 , pp. 1081-1091
    • Wang, M.1    Zhang, W.B.2    Zhu, J.H.3    Fu, G.S.4    Zhou, B.Q.5
  • 49
    • 79952727485 scopus 로고    scopus 로고
    • Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure
    • Song Y.H., Cai H., Gu N., Qian C.F., Cao S.P., Zhao Z.M. Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure. J Pharm Pharmacol 2011, 63(4):541-549.
    • (2011) J Pharm Pharmacol , vol.63 , Issue.4 , pp. 541-549
    • Song, Y.H.1    Cai, H.2    Gu, N.3    Qian, C.F.4    Cao, S.P.5    Zhao, Z.M.6
  • 50
    • 34548331134 scopus 로고    scopus 로고
    • Impact of Pycnogenol on cardiac extracellular matrix remodeling induced by L-NAME administration to old mice
    • Zibadi S., Yu Q., Rohdewald P.J., Larson D.F., Watson R.R. Impact of Pycnogenol on cardiac extracellular matrix remodeling induced by L-NAME administration to old mice. Cardiovasc Toxicol 2007, 7(1):10-18.
    • (2007) Cardiovasc Toxicol , vol.7 , Issue.1 , pp. 10-18
    • Zibadi, S.1    Yu, Q.2    Rohdewald, P.J.3    Larson, D.F.4    Watson, R.R.5
  • 51
    • 40549135974 scopus 로고    scopus 로고
    • The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats
    • Morimoto T., Sunagawa Y., Kawamura T., Takaya T., Wada H., Nagasawa A., et al. The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats. J Clin Invest 2008, 118(3):868-878.
    • (2008) J Clin Invest , vol.118 , Issue.3 , pp. 868-878
    • Morimoto, T.1    Sunagawa, Y.2    Kawamura, T.3    Takaya, T.4    Wada, H.5    Nagasawa, A.6
  • 52
    • 52949108394 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the transition of cardiac hypertrophy to heart failure
    • Oka T., Komuro I. Molecular mechanisms underlying the transition of cardiac hypertrophy to heart failure. Circ J 2008, 72(Suppl. A):A13-16.
    • (2008) Circ J , vol.72 , Issue.SUPPL. A
    • Oka, T.1    Komuro, I.2
  • 53
    • 78751647632 scopus 로고    scopus 로고
    • Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling
    • Mishra S., Ling H., Grimm M., Zhang T., Bers D.M., Brown J.H. Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling. J Cardiovasc Pharmacol 2010, 56(6):598-603.
    • (2010) J Cardiovasc Pharmacol , vol.56 , Issue.6 , pp. 598-603
    • Mishra, S.1    Ling, H.2    Grimm, M.3    Zhang, T.4    Bers, D.M.5    Brown, J.H.6
  • 54
    • 84882904015 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II
    • Academic Press, 565-568, A. BR., E.A. Dennis (Eds.), 2nd ed.
    • Kennedy M.B. Calcium/calmodulin-dependent protein kinase II. Handbook of Cell Signaling 2010, Academic Press, 565-568. 2nd ed. A. BR., E.A. Dennis (Eds.).
    • (2010) Handbook of Cell Signaling
    • Kennedy, M.B.1
  • 55
    • 68749093777 scopus 로고    scopus 로고
    • Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress
    • Xu Y., Lin D., Li S., Li G., Shyamala S.G., Barish P.A., et al. Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress. Neuropharmacology 2009, 57(4):463-471.
    • (2009) Neuropharmacology , vol.57 , Issue.4 , pp. 463-471
    • Xu, Y.1    Lin, D.2    Li, S.3    Li, G.4    Shyamala, S.G.5    Barish, P.A.6
  • 56
    • 27144527121 scopus 로고    scopus 로고
    • Targeting calcineurin and associated pathways in cardiac hypertrophy and failure
    • Fiedler B., Wollert K.C. Targeting calcineurin and associated pathways in cardiac hypertrophy and failure. Expert Opin Ther Targets 2005, 9(5):963-973.
    • (2005) Expert Opin Ther Targets , vol.9 , Issue.5 , pp. 963-973
    • Fiedler, B.1    Wollert, K.C.2
  • 57
    • 76949108466 scopus 로고    scopus 로고
    • Inhibition of calcineurin by quercetin in vitro and in Jurkat cells
    • Wang H., Zhou C.L., Lei H., Wei Q. Inhibition of calcineurin by quercetin in vitro and in Jurkat cells. J Biochem 2010, 147(2):185-190.
    • (2010) J Biochem , vol.147 , Issue.2 , pp. 185-190
    • Wang, H.1    Zhou, C.L.2    Lei, H.3    Wei, Q.4
  • 58
    • 52049122868 scopus 로고    scopus 로고
    • Kaempferol: a new immunosuppressant of calcineurin
    • Wang H., Zhou C.L., Lei H., Zhang S.D., Zheng J., Wei Q. Kaempferol: a new immunosuppressant of calcineurin. IUBMB Life 2008, 60(8):549-554.
    • (2008) IUBMB Life , vol.60 , Issue.8 , pp. 549-554
    • Wang, H.1    Zhou, C.L.2    Lei, H.3    Zhang, S.D.4    Zheng, J.5    Wei, Q.6
  • 59
    • 78149478401 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale
    • Rose B.A., Force T., Wang Y. Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 2010, 90(4):1507-1546.
    • (2010) Physiol Rev , vol.90 , Issue.4 , pp. 1507-1546
    • Rose, B.A.1    Force, T.2    Wang, Y.3
  • 60
    • 0035355360 scopus 로고    scopus 로고
    • Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy
    • Nicol R.L., Frey N., Pearson G., Cobb M., Richardson J., Olson E.N. Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. EMBO J 2001, 20(11):2757-2767.
    • (2001) EMBO J , vol.20 , Issue.11 , pp. 2757-2767
    • Nicol, R.L.1    Frey, N.2    Pearson, G.3    Cobb, M.4    Richardson, J.5    Olson, E.N.6
  • 61
    • 77950909970 scopus 로고    scopus 로고
    • Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart
    • Kimura T.E., Jin J., Zi M., Prehar S., Liu W., Oceandy D., et al. Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart. Circ Res 2010, 106(5):961-970.
    • (2010) Circ Res , vol.106 , Issue.5 , pp. 961-970
    • Kimura, T.E.1    Jin, J.2    Zi, M.3    Prehar, S.4    Liu, W.5    Oceandy, D.6
  • 62
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis J.M., Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001, 81(2):807-869.
    • (2001) Physiol Rev , vol.81 , Issue.2 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 63
    • 51749113325 scopus 로고    scopus 로고
    • Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway
    • Li Z., Li J., Mo B., Hu C., Liu H., Qi H., et al. Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway. Toxicol In Vitro 2008, 22(7):1749-1753.
    • (2008) Toxicol In Vitro , vol.22 , Issue.7 , pp. 1749-1753
    • Li, Z.1    Li, J.2    Mo, B.3    Hu, C.4    Liu, H.5    Qi, H.6
  • 64
    • 0028106710 scopus 로고
    • The tyrosine kinase inhibitor, genistein, prevents alpha-adrenergic-induced cardiac muscle cell hypertrophy by inhibiting activation of the Ras-MAP kinase signaling pathway
    • Thorburn J., Thorburn A. The tyrosine kinase inhibitor, genistein, prevents alpha-adrenergic-induced cardiac muscle cell hypertrophy by inhibiting activation of the Ras-MAP kinase signaling pathway. Biochem Biophys Res Commun 1994, 202(3):1586-1591.
    • (1994) Biochem Biophys Res Commun , vol.202 , Issue.3 , pp. 1586-1591
    • Thorburn, J.1    Thorburn, A.2
  • 65
    • 77957733987 scopus 로고    scopus 로고
    • Genistein prevents myocardial hypertrophy in 2-kidney 1-clip renal hypertensive rats by restoring eNOS pathway
    • Li J., Xie Z.Z., Tang Y.B. Genistein prevents myocardial hypertrophy in 2-kidney 1-clip renal hypertensive rats by restoring eNOS pathway. Pharmacology 2010, 86(4):240-248.
    • (2010) Pharmacology , vol.86 , Issue.4 , pp. 240-248
    • Li, J.1    Xie, Z.Z.2    Tang, Y.B.3
  • 66
    • 79955936789 scopus 로고    scopus 로고
    • Black tea polyphenol theaflavin suppresses LPS-induced ICAM-1 and VCAM-1 expression via blockage of NF-kappaB and JNK activation in intestinal epithelial cells
    • Song Y.A., Park Y.L., Yoon S.H., Kim K.Y., Cho S.B., Lee W.S., et al. Black tea polyphenol theaflavin suppresses LPS-induced ICAM-1 and VCAM-1 expression via blockage of NF-kappaB and JNK activation in intestinal epithelial cells. Inflamm Res 2011, 60(5):493-500.
    • (2011) Inflamm Res , vol.60 , Issue.5 , pp. 493-500
    • Song, Y.A.1    Park, Y.L.2    Yoon, S.H.3    Kim, K.Y.4    Cho, S.B.5    Lee, W.S.6
  • 67
    • 70349606667 scopus 로고    scopus 로고
    • Role of oxidation-triggered activation of JNK and p38 MAPK in black tea polyphenols induced apoptotic death of A375 cells
    • Bhattacharya U., Halder B., Mukhopadhyay S., Giri A.K. Role of oxidation-triggered activation of JNK and p38 MAPK in black tea polyphenols induced apoptotic death of A375 cells. Cancer Sci 2009, 100(10):1971-1978.
    • (2009) Cancer Sci , vol.100 , Issue.10 , pp. 1971-1978
    • Bhattacharya, U.1    Halder, B.2    Mukhopadhyay, S.3    Giri, A.K.4
  • 68
    • 84860285260 scopus 로고    scopus 로고
    • Angiotensin II induces inflammation leading to cardiac remodeling
    • Jia L., Li Y., Xiao C., Du J. Angiotensin II induces inflammation leading to cardiac remodeling. Front Biosci 2012, 17:221-231.
    • (2012) Front Biosci , vol.17 , pp. 221-231
    • Jia, L.1    Li, Y.2    Xiao, C.3    Du, J.4
  • 69
    • 77955896408 scopus 로고    scopus 로고
    • Targeting the vicious inflammation-oxidative stress cycle for the management of heart failure
    • Khaper N., Bryan S., Dhingra S., Singal R., Bajaj A., Pathak C.M., et al. Targeting the vicious inflammation-oxidative stress cycle for the management of heart failure. Antioxid Redox Signal 2010, 13(7):1033-1049.
    • (2010) Antioxid Redox Signal , vol.13 , Issue.7 , pp. 1033-1049
    • Khaper, N.1    Bryan, S.2    Dhingra, S.3    Singal, R.4    Bajaj, A.5    Pathak, C.M.6
  • 70
    • 80155198133 scopus 로고    scopus 로고
    • The role of monocytes and inflammation in the pathophysiology of heart failure
    • Wrigley B.J., Lip G.Y., Shantsila E. The role of monocytes and inflammation in the pathophysiology of heart failure. Eur J Heart Fail 2011, 13(11):1161-1171.
    • (2011) Eur J Heart Fail , vol.13 , Issue.11 , pp. 1161-1171
    • Wrigley, B.J.1    Lip, G.Y.2    Shantsila, E.3
  • 71
    • 77955510430 scopus 로고    scopus 로고
    • The paradoxical role of inflammation in cardiac repair and regeneration
    • Jiang B., Liao R. The paradoxical role of inflammation in cardiac repair and regeneration. J Cardiovasc Transl Res 2010, 3(4):410-416.
    • (2010) J Cardiovasc Transl Res , vol.3 , Issue.4 , pp. 410-416
    • Jiang, B.1    Liao, R.2
  • 72
    • 59449085857 scopus 로고    scopus 로고
    • Post-infarct remodelling: contribution of wound healing and inflammation
    • Frantz S., Bauersachs J., Ertl G. Post-infarct remodelling: contribution of wound healing and inflammation. Cardiovasc Res 2009, 81(3):474-481.
    • (2009) Cardiovasc Res , vol.81 , Issue.3 , pp. 474-481
    • Frantz, S.1    Bauersachs, J.2    Ertl, G.3
  • 73
    • 3042759124 scopus 로고    scopus 로고
    • Natural phenolic compounds as cardiovascular therapeutics: potential role of their antiinflammatory effects
    • Jiang F., Dusting G.J. Natural phenolic compounds as cardiovascular therapeutics: potential role of their antiinflammatory effects. Curr Vasc Pharmacol 2003, 1(2):135-156.
    • (2003) Curr Vasc Pharmacol , vol.1 , Issue.2 , pp. 135-156
    • Jiang, F.1    Dusting, G.J.2
  • 74
    • 7444239011 scopus 로고    scopus 로고
    • Epigallocatechin a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats
    • Aneja R., Hake P.W., Burroughs T.J., Denenberg A.G., Wong H.R., Zingarelli B. Epigallocatechin a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats. Mol Med 2004, 10(1-6):55-62.
    • (2004) Mol Med , vol.10 , Issue.1-6 , pp. 55-62
    • Aneja, R.1    Hake, P.W.2    Burroughs, T.J.3    Denenberg, A.G.4    Wong, H.R.5    Zingarelli, B.6
  • 75
    • 32344437926 scopus 로고    scopus 로고
    • Anthocyanins from soybean seed coat inhibit the expression of TNF-alpha-induced genes associated with ischemia/reperfusion in endothelial cell by NF-kappaB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo
    • Kim H.J., Tsoy I., Park J.M., Chung J.I., Shin S.C., Chang K.C. Anthocyanins from soybean seed coat inhibit the expression of TNF-alpha-induced genes associated with ischemia/reperfusion in endothelial cell by NF-kappaB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo. FEBS Lett 2006, 580(5):1391-1397.
    • (2006) FEBS Lett , vol.580 , Issue.5 , pp. 1391-1397
    • Kim, H.J.1    Tsoy, I.2    Park, J.M.3    Chung, J.I.4    Shin, S.C.5    Chang, K.C.6
  • 76
    • 70349921185 scopus 로고    scopus 로고
    • 3',4'-Dihydroxyflavonol down-regulates monocyte chemoattractant protein-1 in smooth muscle: role of focal adhesion kinase and PDGF receptor signalling
    • Jiang F., Guo N., Dusting G.J. 3',4'-Dihydroxyflavonol down-regulates monocyte chemoattractant protein-1 in smooth muscle: role of focal adhesion kinase and PDGF receptor signalling. Br J Pharmacol 2009, 157(4):597-606.
    • (2009) Br J Pharmacol , vol.157 , Issue.4 , pp. 597-606
    • Jiang, F.1    Guo, N.2    Dusting, G.J.3
  • 77
    • 22744444997 scopus 로고    scopus 로고
    • Blockade of NF-kappaB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II
    • Kawano S., Kubota T., Monden Y., Kawamura N., Tsutsui H., Takeshita A., et al. Blockade of NF-kappaB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II. Cardiovasc Res 2005, 67(4):689-698.
    • (2005) Cardiovasc Res , vol.67 , Issue.4 , pp. 689-698
    • Kawano, S.1    Kubota, T.2    Monden, Y.3    Kawamura, N.4    Tsutsui, H.5    Takeshita, A.6
  • 78
    • 78650443223 scopus 로고    scopus 로고
    • Cardiomyocyte NF-kappaB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure
    • Hamid T., Guo S.Z., Kingery J.R., Xiang X., Dawn B., Prabhu S.D. Cardiomyocyte NF-kappaB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure. Cardiovasc Res 2011, 89(1):129-138.
    • (2011) Cardiovasc Res , vol.89 , Issue.1 , pp. 129-138
    • Hamid, T.1    Guo, S.Z.2    Kingery, J.R.3    Xiang, X.4    Dawn, B.5    Prabhu, S.D.6
  • 79
    • 0034859081 scopus 로고    scopus 로고
    • The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6
    • Yang F., Oz H.S., Barve S., de Villiers W.J., McClain C.J., Varilek G.W. The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6. Mol Pharmacol 2001, 60(3):528-533.
    • (2001) Mol Pharmacol , vol.60 , Issue.3 , pp. 528-533
    • Yang, F.1    Oz, H.S.2    Barve, S.3    de Villiers, W.J.4    McClain, C.J.5    Varilek, G.W.6
  • 80
    • 34250003762 scopus 로고    scopus 로고
    • Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis
    • Kunnumakkara A.B., Nair A.S., Ahn K.S., Pandey M.K., Yi Z., Liu M., et al. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Blood 2007, 109(12):5112-5121.
    • (2007) Blood , vol.109 , Issue.12 , pp. 5112-5121
    • Kunnumakkara, A.B.1    Nair, A.S.2    Ahn, K.S.3    Pandey, M.K.4    Yi, Z.5    Liu, M.6
  • 81
    • 0033568674 scopus 로고    scopus 로고
    • Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity
    • Jobin C., Bradham C.A., Russo M.P., Juma B., Narula A.S., Brenner D.A., et al. Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J Immunol 1999, 163(6):3474-3483.
    • (1999) J Immunol , vol.163 , Issue.6 , pp. 3474-3483
    • Jobin, C.1    Bradham, C.A.2    Russo, M.P.3    Juma, B.4    Narula, A.S.5    Brenner, D.A.6
  • 82
    • 0037305821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
    • Bharti A.C., Donato N., Singh S., Aggarwal B.B. Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood 2003, 101(3):1053-1062.
    • (2003) Blood , vol.101 , Issue.3 , pp. 1053-1062
    • Bharti, A.C.1    Donato, N.2    Singh, S.3    Aggarwal, B.B.4
  • 83
    • 15744363537 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activation can attenuate ischemia/reperfusion-induced contractility impairment via decreasing cardiomyocytic proinflammatory gene up-regulation and matrix metalloproteinase expression
    • Yeh C.H., Lin Y.M., Wu Y.C., Lin P.J. Inhibition of NF-kappa B activation can attenuate ischemia/reperfusion-induced contractility impairment via decreasing cardiomyocytic proinflammatory gene up-regulation and matrix metalloproteinase expression. J Cardiovasc Pharmacol 2005, 45(4):301-309.
    • (2005) J Cardiovasc Pharmacol , vol.45 , Issue.4 , pp. 301-309
    • Yeh, C.H.1    Lin, Y.M.2    Wu, Y.C.3    Lin, P.J.4
  • 86
    • 49749096009 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in urotensin II-induced proliferation of cardiac fibroblasts
    • Chen Y.L., Liu J.C., Loh S.H., Chen C.H., Hong C.Y., Chen J.J., et al. Involvement of reactive oxygen species in urotensin II-induced proliferation of cardiac fibroblasts. Eur J Pharmacol 2008, 593(1-3):24-29.
    • (2008) Eur J Pharmacol , vol.593 , Issue.1-3 , pp. 24-29
    • Chen, Y.L.1    Liu, J.C.2    Loh, S.H.3    Chen, C.H.4    Hong, C.Y.5    Chen, J.J.6
  • 87
    • 33645517324 scopus 로고    scopus 로고
    • Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species
    • Lijnen P., Papparella I., Petrov V., Semplicini A., Fagard R. Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species. J Hypertens 2006, 24(4):757-766.
    • (2006) J Hypertens , vol.24 , Issue.4 , pp. 757-766
    • Lijnen, P.1    Papparella, I.2    Petrov, V.3    Semplicini, A.4    Fagard, R.5
  • 88
    • 79952734249 scopus 로고    scopus 로고
    • Cytoprotection by natural and synthetic polyphenols in the heart: novel mechanisms and perspectives
    • Jiang F., Chang C.W., Dusting G.J. Cytoprotection by natural and synthetic polyphenols in the heart: novel mechanisms and perspectives. Curr Pharm Des 2010, 16(37):4103-4112.
    • (2010) Curr Pharm Des , vol.16 , Issue.37 , pp. 4103-4112
    • Jiang, F.1    Chang, C.W.2    Dusting, G.J.3
  • 90
    • 0037154308 scopus 로고    scopus 로고
    • Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice
    • Bendall J.K., Cave A.C., Heymes C., Gall N., Shah A.M. Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation 2002, 105(3):293-296.
    • (2002) Circulation , vol.105 , Issue.3 , pp. 293-296
    • Bendall, J.K.1    Cave, A.C.2    Heymes, C.3    Gall, N.4    Shah, A.M.5
  • 92
    • 69249214027 scopus 로고    scopus 로고
    • Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells
    • Jaulmes A., Sansilvestri-Morel P., Rolland-Valognes G., Bernhardt F., Gaertner R., Lockhart B.P., et al. Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells. Thromb Res 2009, 124(4):439-446.
    • (2009) Thromb Res , vol.124 , Issue.4 , pp. 439-446
    • Jaulmes, A.1    Sansilvestri-Morel, P.2    Rolland-Valognes, G.3    Bernhardt, F.4    Gaertner, R.5    Lockhart, B.P.6
  • 93
    • 37349044689 scopus 로고    scopus 로고
    • Modulation of nicotinamide adenine dinucleotide phosphate oxidase expression and function by 3',4'-dihydroxyflavonol in phagocytic and vascular cells
    • Jiang F., Guo N., Dusting G.J. Modulation of nicotinamide adenine dinucleotide phosphate oxidase expression and function by 3',4'-dihydroxyflavonol in phagocytic and vascular cells. J Pharmacol Exp Ther 2008, 324(1):261-269.
    • (2008) J Pharmacol Exp Ther , vol.324 , Issue.1 , pp. 261-269
    • Jiang, F.1    Guo, N.2    Dusting, G.J.3
  • 94
    • 29144446282 scopus 로고    scopus 로고
    • Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats
    • Sanchez M., Galisteo M., Vera R., Villar I.C., Zarzuelo A., Tamargo J., et al. Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. J Hypertens 2006, 24(1):75-84.
    • (2006) J Hypertens , vol.24 , Issue.1 , pp. 75-84
    • Sanchez, M.1    Galisteo, M.2    Vera, R.3    Villar, I.C.4    Zarzuelo, A.5    Tamargo, J.6
  • 95
    • 79952026736 scopus 로고    scopus 로고
    • NADPH oxidase-mediated redox signaling: roles in cellular stress response, stress tolerance, and tissue repair
    • Jiang F., Zhang Y., Dusting G.J. NADPH oxidase-mediated redox signaling: roles in cellular stress response, stress tolerance, and tissue repair. Pharmacol Rev 2011, 63(1):218-242.
    • (2011) Pharmacol Rev , vol.63 , Issue.1 , pp. 218-242
    • Jiang, F.1    Zhang, Y.2    Dusting, G.J.3
  • 96
    • 84874081484 scopus 로고    scopus 로고
    • NADPH oxidases in heart failure: poachers or gamekeepers?
    • Zhang M., Perino A., Ghigo A., Hirsch E., Shah A. NADPH oxidases in heart failure: poachers or gamekeepers?. Antioxid Redox Signal 2012, 18(9):1024-1041.
    • (2012) Antioxid Redox Signal , vol.18 , Issue.9 , pp. 1024-1041
    • Zhang, M.1    Perino, A.2    Ghigo, A.3    Hirsch, E.4    Shah, A.5
  • 97
    • 13844312743 scopus 로고    scopus 로고
    • The cardiac fibroblast: therapeutic target in myocardial remodeling and failure
    • Brown R.D., Ambler S.K., Mitchell M.D., Long C.S. The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 2005, 45:657-687.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 657-687
    • Brown, R.D.1    Ambler, S.K.2    Mitchell, M.D.3    Long, C.S.4
  • 98
    • 73349122017 scopus 로고    scopus 로고
    • Cardiac fibroblast: the renaissance cell
    • Souders C.A., Bowers S.L., Baudino T.A. Cardiac fibroblast: the renaissance cell. Circ Res 2009, 105(12):1164-1176.
    • (2009) Circ Res , vol.105 , Issue.12 , pp. 1164-1176
    • Souders, C.A.1    Bowers, S.L.2    Baudino, T.A.3
  • 99
    • 78651420043 scopus 로고    scopus 로고
    • Scutellarin alleviates interstitial fibrosis and cardiac dysfunction of infarct rats by inhibiting TGFbeta1 expression and activation of p38-MAPK and ERK1/2
    • Pan Z., Zhao W., Zhang X., Wang B., Wang J., Sun X., et al. Scutellarin alleviates interstitial fibrosis and cardiac dysfunction of infarct rats by inhibiting TGFbeta1 expression and activation of p38-MAPK and ERK1/2. Br J Pharmacol 2011, 162(3):688-700.
    • (2011) Br J Pharmacol , vol.162 , Issue.3 , pp. 688-700
    • Pan, Z.1    Zhao, W.2    Zhang, X.3    Wang, B.4    Wang, J.5    Sun, X.6
  • 100
    • 79955492201 scopus 로고    scopus 로고
    • Attenuation of transforming growth factor-beta-stimulated collagen production in fibroblasts by quercetin-induced heme oxygenase-1
    • Nakamura T., Matsushima M., Hayashi Y., Shibasaki M., Imaizumi K., Hashimoto N., et al. Attenuation of transforming growth factor-beta-stimulated collagen production in fibroblasts by quercetin-induced heme oxygenase-1. Am J Respir Cell Mol Biol 2011, 44(5):614-620.
    • (2011) Am J Respir Cell Mol Biol , vol.44 , Issue.5 , pp. 614-620
    • Nakamura, T.1    Matsushima, M.2    Hayashi, Y.3    Shibasaki, M.4    Imaizumi, K.5    Hashimoto, N.6
  • 101
    • 78751507979 scopus 로고    scopus 로고
    • Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart
    • Creemers E.E., Pinto Y.M. Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart. Cardiovasc Res 2011, 89(2):265-272.
    • (2011) Cardiovasc Res , vol.89 , Issue.2 , pp. 265-272
    • Creemers, E.E.1    Pinto, Y.M.2
  • 102
    • 84868134336 scopus 로고    scopus 로고
    • Effects of epigallocatechin-3-gallate on the expression of TGF-beta1, PKC alpha/betaII, and NF-kappaB in high-glucose-stimulated glomerular epithelial cells
    • Park S.J., Jeong J.M., Jeong H.S., Park J.S., Kim N.H. Effects of epigallocatechin-3-gallate on the expression of TGF-beta1, PKC alpha/betaII, and NF-kappaB in high-glucose-stimulated glomerular epithelial cells. Chonnam Med J 2011, 47(2):116-121.
    • (2011) Chonnam Med J , vol.47 , Issue.2 , pp. 116-121
    • Park, S.J.1    Jeong, J.M.2    Jeong, H.S.3    Park, J.S.4    Kim, N.H.5
  • 103
    • 82455164280 scopus 로고    scopus 로고
    • Protective effect of Icariin on the early stage of experimental diabetic nephropathy induced by streptozotocin via modulating transforming growth factor beta1 and type IV collagen expression in rats
    • Qi M.Y., Kai C., Liu H.R., Su Y.H., Yu S.Q. Protective effect of Icariin on the early stage of experimental diabetic nephropathy induced by streptozotocin via modulating transforming growth factor beta1 and type IV collagen expression in rats. J Ethnopharmacol 2011, 138(3):731-736.
    • (2011) J Ethnopharmacol , vol.138 , Issue.3 , pp. 731-736
    • Qi, M.Y.1    Kai, C.2    Liu, H.R.3    Su, Y.H.4    Yu, S.Q.5
  • 104
    • 84862491992 scopus 로고    scopus 로고
    • Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-beta1 activity
    • Dandawate S., Williams L., Joshee N., Rimando A.M., Mittal S., Thakur A., et al. Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-beta1 activity. Cancer Immunol Immunother 2012, 61(5):701-711.
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.5 , pp. 701-711
    • Dandawate, S.1    Williams, L.2    Joshee, N.3    Rimando, A.M.4    Mittal, S.5    Thakur, A.6
  • 105
    • 79955147792 scopus 로고    scopus 로고
    • A single-molecule study of the inhibition effect of Naringenin on transforming growth factor-beta ligand-receptor binding
    • Yang Y., Xu Y., Xia T., Chen F., Zhang C., Liang W., et al. A single-molecule study of the inhibition effect of Naringenin on transforming growth factor-beta ligand-receptor binding. Chem Commun (Camb) 2011, 47(19):5440-5442.
    • (2011) Chem Commun (Camb) , vol.47 , Issue.19 , pp. 5440-5442
    • Yang, Y.1    Xu, Y.2    Xia, T.3    Chen, F.4    Zhang, C.5    Liang, W.6
  • 106
    • 32244440927 scopus 로고    scopus 로고
    • Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta1 in cultured rat hepatic stellate cells
    • Liu X., Wang W., Hu H., Tang N., Zhang C., Liang W., et al. Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta1 in cultured rat hepatic stellate cells. Pharm Res 2006, 23(1):82-89.
    • (2006) Pharm Res , vol.23 , Issue.1 , pp. 82-89
    • Liu, X.1    Wang, W.2    Hu, H.3    Tang, N.4    Zhang, C.5    Liang, W.6
  • 107
    • 9644263886 scopus 로고    scopus 로고
    • Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars
    • Phan T.T., Lim I.J., Chan S.Y., Tan E.K., Lee S.T., Longaker M.T. Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars. J Trauma 2004, 57(5):1032-1037.
    • (2004) J Trauma , vol.57 , Issue.5 , pp. 1032-1037
    • Phan, T.T.1    Lim, I.J.2    Chan, S.Y.3    Tan, E.K.4    Lee, S.T.5    Longaker, M.T.6
  • 108
    • 0035800880 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure?
    • Creemers E.E., Cleutjens J.P., Smits J.F., Daemen M.J. Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure?. Circ Res 2001, 89(3):201-210.
    • (2001) Circ Res , vol.89 , Issue.3 , pp. 201-210
    • Creemers, E.E.1    Cleutjens, J.P.2    Smits, J.F.3    Daemen, M.J.4
  • 110
    • 33644693111 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells
    • Nakamuta M., Higashi N., Kohjima M., Fukushima M., Ohta S., Kotoh K., et al. Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. Int J Mol Med 2005, 16(4):677-681.
    • (2005) Int J Mol Med , vol.16 , Issue.4 , pp. 677-681
    • Nakamuta, M.1    Higashi, N.2    Kohjima, M.3    Fukushima, M.4    Ohta, S.5    Kotoh, K.6
  • 111
    • 0346117568 scopus 로고    scopus 로고
    • Inhibitory effect of green tea polyphenols on membrane-type 1 matrix metalloproteinase, MT1-MMP
    • Oku N., Matsukawa M., Yamakawa S., Asai T., Yahara S., Hashimoto F., et al. Inhibitory effect of green tea polyphenols on membrane-type 1 matrix metalloproteinase, MT1-MMP. Biol Pharm Bull 2003, 26(9):1235-1238.
    • (2003) Biol Pharm Bull , vol.26 , Issue.9 , pp. 1235-1238
    • Oku, N.1    Matsukawa, M.2    Yamakawa, S.3    Asai, T.4    Yahara, S.5    Hashimoto, F.6
  • 112
    • 21744437098 scopus 로고    scopus 로고
    • Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression
    • El Bedoui J., Oak M.H., Anglard P., Schini-Kerth V.B. Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. Cardiovasc Res 2005, 67(2):317-325.
    • (2005) Cardiovasc Res , vol.67 , Issue.2 , pp. 317-325
    • El Bedoui, J.1    Oak, M.H.2    Anglard, P.3    Schini-Kerth, V.B.4
  • 113
    • 1342328148 scopus 로고    scopus 로고
    • Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol)
    • Grimm T., Schafer A., Hogger P. Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol). Free Radic Biol Med 2004, 36(6):811-822.
    • (2004) Free Radic Biol Med , vol.36 , Issue.6 , pp. 811-822
    • Grimm, T.1    Schafer, A.2    Hogger, P.3
  • 114
    • 0036812988 scopus 로고    scopus 로고
    • Regulation of cardiac remodeling by nitric oxide: focus on cardiac myocyte hypertrophy and apoptosis
    • Wollert K.C., Drexler H. Regulation of cardiac remodeling by nitric oxide: focus on cardiac myocyte hypertrophy and apoptosis. Heart Fail Rev 2002, 7(4):317-325.
    • (2002) Heart Fail Rev , vol.7 , Issue.4 , pp. 317-325
    • Wollert, K.C.1    Drexler, H.2
  • 115
    • 36448954982 scopus 로고    scopus 로고
    • LA419, a novel nitric oxide donor, prevents pathological cardiac remodeling in pressure-overloaded rats via endothelial nitric oxide synthase pathway regulation
    • Ruiz-Hurtado G., Fernandez-Velasco M., Mourelle M., Delgado C. LA419, a novel nitric oxide donor, prevents pathological cardiac remodeling in pressure-overloaded rats via endothelial nitric oxide synthase pathway regulation. Hypertension 2007, 50(6):1049-1056.
    • (2007) Hypertension , vol.50 , Issue.6 , pp. 1049-1056
    • Ruiz-Hurtado, G.1    Fernandez-Velasco, M.2    Mourelle, M.3    Delgado, C.4
  • 116
    • 19444372119 scopus 로고    scopus 로고
    • Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload
    • Ruetten H., Dimmeler S., Gehring D., Ihling C., Zeiher A.M. Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload. Cardiovasc Res 2005, 66(3):444-453.
    • (2005) Cardiovasc Res , vol.66 , Issue.3 , pp. 444-453
    • Ruetten, H.1    Dimmeler, S.2    Gehring, D.3    Ihling, C.4    Zeiher, A.M.5
  • 117
    • 84857367504 scopus 로고    scopus 로고
    • Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides
    • Calvieri C., Rubattu S., Volpe M. Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides. J Mol Med (Berl) 2011, 90(1):5-13.
    • (2011) J Mol Med (Berl) , vol.90 , Issue.1 , pp. 5-13
    • Calvieri, C.1    Rubattu, S.2    Volpe, M.3
  • 118
    • 65649143876 scopus 로고    scopus 로고
    • Natriuretic peptide signaling via guanylyl cyclase (GC)-A: an endogenous protective mechanism of the heart
    • Kishimoto I., Tokudome T., Horio T., Garbers D.L., Nakao K., Kangawa K. Natriuretic peptide signaling via guanylyl cyclase (GC)-A: an endogenous protective mechanism of the heart. Curr Cardiol Rev 2009, 5(1):45-51.
    • (2009) Curr Cardiol Rev , vol.5 , Issue.1 , pp. 45-51
    • Kishimoto, I.1    Tokudome, T.2    Horio, T.3    Garbers, D.L.4    Nakao, K.5    Kangawa, K.6
  • 119
    • 84856008116 scopus 로고    scopus 로고
    • Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling
    • Hammond J., Balligand J.L. Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling. J Mol Cell Cardiol 2012, 52(2):330-340.
    • (2012) J Mol Cell Cardiol , vol.52 , Issue.2 , pp. 330-340
    • Hammond, J.1    Balligand, J.L.2
  • 120
    • 0026703056 scopus 로고
    • Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system"
    • Suga S., Nakao K., Itoh H., Komatsu Y., Ogawa Y., Hama N., et al. Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system". J Clin Invest 1992, 90(3):1145-1149.
    • (1992) J Clin Invest , vol.90 , Issue.3 , pp. 1145-1149
    • Suga, S.1    Nakao, K.2    Itoh, H.3    Komatsu, Y.4    Ogawa, Y.5    Hama, N.6
  • 121
    • 84866162509 scopus 로고    scopus 로고
    • Chronic C-type natriuretic peptide infusion attenuates angiotensin II-induced myocardial superoxide production and cardiac remodeling
    • Izumiya Y., Araki S., Usuku H., Rokutanda T., Hanatani S., Ogawa H. Chronic C-type natriuretic peptide infusion attenuates angiotensin II-induced myocardial superoxide production and cardiac remodeling. Int J Vasc Med 2012, 2012:246058.
    • (2012) Int J Vasc Med , vol.2012 , pp. 246058
    • Izumiya, Y.1    Araki, S.2    Usuku, H.3    Rokutanda, T.4    Hanatani, S.5    Ogawa, H.6
  • 122
    • 0038391490 scopus 로고    scopus 로고
    • Multiple signalling options for prostacyclin
    • Wise H. Multiple signalling options for prostacyclin. Acta Pharmacol Sin 2003, 24(7):625-630.
    • (2003) Acta Pharmacol Sin , vol.24 , Issue.7 , pp. 625-630
    • Wise, H.1
  • 123
    • 27744528125 scopus 로고    scopus 로고
    • Prostacyclin protects against elevated blood pressure and cardiac fibrosis
    • Francois H., Athirakul K., Howell D., Dash R., Mao L., Kim H.S., et al. Prostacyclin protects against elevated blood pressure and cardiac fibrosis. Cell Metab 2005, 2(3):201-207.
    • (2005) Cell Metab , vol.2 , Issue.3 , pp. 201-207
    • Francois, H.1    Athirakul, K.2    Howell, D.3    Dash, R.4    Mao, L.5    Kim, H.S.6
  • 124
    • 21844453647 scopus 로고    scopus 로고
    • Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor
    • Hara A., Yuhki K., Fujino T., Yamada T., Takayama K., Kuriyama S., et al. Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor. Circulation 2005, 112(1):84-92.
    • (2005) Circulation , vol.112 , Issue.1 , pp. 84-92
    • Hara, A.1    Yuhki, K.2    Fujino, T.3    Yamada, T.4    Takayama, K.5    Kuriyama, S.6
  • 127
    • 27144500230 scopus 로고    scopus 로고
    • Effects of phytoestrogens genistein and daidzein on prostacyclin production by human endothelial cells
    • Hermenegildo C., Oviedo P.J., Garcia-Perez M.A., Tarin J.J., Cano A. Effects of phytoestrogens genistein and daidzein on prostacyclin production by human endothelial cells. J Pharmacol Exp Ther 2005, 315(2):722-728.
    • (2005) J Pharmacol Exp Ther , vol.315 , Issue.2 , pp. 722-728
    • Hermenegildo, C.1    Oviedo, P.J.2    Garcia-Perez, M.A.3    Tarin, J.J.4    Cano, A.5
  • 128
    • 27744553563 scopus 로고    scopus 로고
    • The comparison of the relaxant effects of two methoxylated flavones in rat aortic rings
    • Uydes-Dogan B.S., Takir S., Ozdemir O., Kolak U., Topcu G., Ulubelen A. The comparison of the relaxant effects of two methoxylated flavones in rat aortic rings. Vascul Pharmacol 2005, 43(4):220-226.
    • (2005) Vascul Pharmacol , vol.43 , Issue.4 , pp. 220-226
    • Uydes-Dogan, B.S.1    Takir, S.2    Ozdemir, O.3    Kolak, U.4    Topcu, G.5    Ulubelen, A.6
  • 130
    • 0034600758 scopus 로고    scopus 로고
    • Epigallocatechin gallate increase the prostacyclin production of bovine aortic endothelial cells
    • Mizugaki M., Ishizawa F., Yamazaki T., Hishinuma T. Epigallocatechin gallate increase the prostacyclin production of bovine aortic endothelial cells. Prostaglandins Other Lipid Mediat 2000, 62(2):157-164.
    • (2000) Prostaglandins Other Lipid Mediat , vol.62 , Issue.2 , pp. 157-164
    • Mizugaki, M.1    Ishizawa, F.2    Yamazaki, T.3    Hishinuma, T.4
  • 133
    • 67650221201 scopus 로고    scopus 로고
    • Autophagy, redox signaling, and ventricular remodeling
    • Gurusamy N., Das D.K Autophagy, redox signaling, and ventricular remodeling. Antioxid Redox Signal 2009, 11(8):1975-1988.
    • (2009) Antioxid Redox Signal , vol.11 , Issue.8 , pp. 1975-1988
    • Gurusamy, N.1    Das, D.K.2
  • 134
    • 34249714158 scopus 로고    scopus 로고
    • The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
    • Nakai A., Yamaguchi O., Takeda T., Higuchi Y., Hikoso S., Taniike M., et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med 2007, 13(5):619-624.
    • (2007) Nat Med , vol.13 , Issue.5 , pp. 619-624
    • Nakai, A.1    Yamaguchi, O.2    Takeda, T.3    Higuchi, Y.4    Hikoso, S.5    Taniike, M.6
  • 135
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y., Takagi H., Qu X., Abdellatif M., Sakoda H., Asano T., et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007, 100(6):914-922.
    • (2007) Circ Res , vol.100 , Issue.6 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3    Abdellatif, M.4    Sakoda, H.5    Asano, T.6
  • 138
    • 84862596482 scopus 로고    scopus 로고
    • Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage
    • Han J., Pan X.Y., Xu Y., Xiao Y., An Y., Tie L., et al. Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage. Autophagy 2012, 8(5):812-825.
    • (2012) Autophagy , vol.8 , Issue.5 , pp. 812-825
    • Han, J.1    Pan, X.Y.2    Xu, Y.3    Xiao, Y.4    An, Y.5    Tie, L.6
  • 139
    • 79953685881 scopus 로고    scopus 로고
    • EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages
    • Li W., Zhu S., Li J., Assa A., Jundoria A., Xu J., et al. EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages. Biochem Pharmacol 2011, 81(9):1152-1163.
    • (2011) Biochem Pharmacol , vol.81 , Issue.9 , pp. 1152-1163
    • Li, W.1    Zhu, S.2    Li, J.3    Assa, A.4    Jundoria, A.5    Xu, J.6
  • 140
    • 84860797901 scopus 로고    scopus 로고
    • Resveratrol protects H9c2 embryonic rat heart derived cells from oxidative stress by inducing autophagy: role of p38 mitogen-activated protein kinase
    • Lv X.C., Zhou H.Y. Resveratrol protects H9c2 embryonic rat heart derived cells from oxidative stress by inducing autophagy: role of p38 mitogen-activated protein kinase. Can J Physiol Pharmacol 2012, 90(5):655-662.
    • (2012) Can J Physiol Pharmacol , vol.90 , Issue.5 , pp. 655-662
    • Lv, X.C.1    Zhou, H.Y.2
  • 141
    • 76249124608 scopus 로고    scopus 로고
    • Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
    • Puissant A., Robert G., Fenouille N., Luciano F., Cassuto J.P., Raynaud S., et al. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. Cancer Res 2010, 70(3):1042-1052.
    • (2010) Cancer Res , vol.70 , Issue.3 , pp. 1042-1052
    • Puissant, A.1    Robert, G.2    Fenouille, N.3    Luciano, F.4    Cassuto, J.P.5    Raynaud, S.6
  • 142
    • 80052359850 scopus 로고    scopus 로고
    • Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease
    • Wu Y., Li X., Zhu J.X., Xie W., Le W., Fan Z., et al. Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease. Neurosignals 2011, 19(3):163-174.
    • (2011) Neurosignals , vol.19 , Issue.3 , pp. 163-174
    • Wu, Y.1    Li, X.2    Zhu, J.X.3    Xie, W.4    Le, W.5    Fan, Z.6
  • 143
    • 77950575506 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism
    • Vingtdeux V., Giliberto L., Zhao H., Chandakkar P., Wu Q., Simon J.E., et al. AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J Biol Chem 2010, 285(12):9100-9113.
    • (2010) J Biol Chem , vol.285 , Issue.12 , pp. 9100-9113
    • Vingtdeux, V.1    Giliberto, L.2    Zhao, H.3    Chandakkar, P.4    Wu, Q.5    Simon, J.E.6
  • 144
    • 79953043473 scopus 로고    scopus 로고
    • Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
    • Morselli E., Maiuri M.C., Markaki M., Megalou E., Pasparaki A., Palikaras K., et al. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell Death Dis 2010, 1:e10.
    • (2010) Cell Death Dis , vol.1
    • Morselli, E.1    Maiuri, M.C.2    Markaki, M.3    Megalou, E.4    Pasparaki, A.5    Palikaras, K.6
  • 145
    • 84863387579 scopus 로고    scopus 로고
    • Resveratrol attenuates doxorubicin-induced cardiomyocyte death via inhibition of p70 S6 kinase 1-mediated autophagy
    • Xu X., Chen K., Kobayashi S., Timm D., Liang Q. Resveratrol attenuates doxorubicin-induced cardiomyocyte death via inhibition of p70 S6 kinase 1-mediated autophagy. J Pharmacol Exp Ther 2012, 341(1):183-195.
    • (2012) J Pharmacol Exp Ther , vol.341 , Issue.1 , pp. 183-195
    • Xu, X.1    Chen, K.2    Kobayashi, S.3    Timm, D.4    Liang, Q.5
  • 146
    • 80052380331 scopus 로고    scopus 로고
    • Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1alpha-mediated signaling
    • Wang K., Liu R., Li J., Mao J., Lei Y., Wu J., et al. Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1alpha-mediated signaling. Autophagy 2011, 7(9):966-978.
    • (2011) Autophagy , vol.7 , Issue.9 , pp. 966-978
    • Wang, K.1    Liu, R.2    Li, J.3    Mao, J.4    Lei, Y.5    Wu, J.6
  • 147
    • 34447092454 scopus 로고    scopus 로고
    • Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells
    • Psahoulia F.H., Moumtzi S., Roberts M.L., Sasazuki T., Shirasawa S., Pintzas A. Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells. Carcinogenesis 2007, 28(5):1021-1031.
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 1021-1031
    • Psahoulia, F.H.1    Moumtzi, S.2    Roberts, M.L.3    Sasazuki, T.4    Shirasawa, S.5    Pintzas, A.6
  • 148
    • 84856975752 scopus 로고    scopus 로고
    • Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease
    • Filomeni G., Graziani I., De Zio D., Dini L., Centonze D., Rotilio G., et al. Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease. Neurobiol Aging 2012, 33(4):767-785.
    • (2012) Neurobiol Aging , vol.33 , Issue.4 , pp. 767-785
    • Filomeni, G.1    Graziani, I.2    De Zio, D.3    Dini, L.4    Centonze, D.5    Rotilio, G.6
  • 151
    • 84860534683 scopus 로고    scopus 로고
    • In vivo recovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of Sirt-1 expression and autophagy in pancreatic beta-cell
    • Wang Q., Liu M., Liu W.W., Hao W.B., Tashiro S., Onodera S., et al. In vivo recovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of Sirt-1 expression and autophagy in pancreatic beta-cell. J Asian Nat Prod Res 2012, 14(5):413-423.
    • (2012) J Asian Nat Prod Res , vol.14 , Issue.5 , pp. 413-423
    • Wang, Q.1    Liu, M.2    Liu, W.W.3    Hao, W.B.4    Tashiro, S.5    Onodera, S.6
  • 152
    • 74349129280 scopus 로고    scopus 로고
    • Persimmon oligomeric proanthocyanidins extend life span of senescence-accelerated mice
    • Yokozawa T., Lee Y.A., Zhao Q., Matsumoto K., Cho E.J. Persimmon oligomeric proanthocyanidins extend life span of senescence-accelerated mice. J Med Food 2009, 12(6):1199-1205.
    • (2009) J Med Food , vol.12 , Issue.6 , pp. 1199-1205
    • Yokozawa, T.1    Lee, Y.A.2    Zhao, Q.3    Matsumoto, K.4    Cho, E.J.5
  • 153
    • 42449100009 scopus 로고    scopus 로고
    • Isoflavones promote mitochondrial biogenesis
    • Rasbach K.A., Schnellmann R.G. Isoflavones promote mitochondrial biogenesis. J Pharmacol Exp Ther 2008, 325(2):536-543.
    • (2008) J Pharmacol Exp Ther , vol.325 , Issue.2 , pp. 536-543
    • Rasbach, K.A.1    Schnellmann, R.G.2
  • 154
    • 84859729838 scopus 로고    scopus 로고
    • Galangin induces autophagy through upregulation of p53 in HepG2 cells
    • Wen M., Wu J., Luo H., Zhang H. Galangin induces autophagy through upregulation of p53 in HepG2 cells. Pharmacology 2012, 89(5-6):247-255.
    • (2012) Pharmacology , vol.89 , Issue.5-6 , pp. 247-255
    • Wen, M.1    Wu, J.2    Luo, H.3    Zhang, H.4
  • 155
    • 84859731822 scopus 로고    scopus 로고
    • Epigenetic modifications in cardiovascular disease
    • Lorenzen J.M., Martino F., Thum T. Epigenetic modifications in cardiovascular disease. Basic Res Cardiol 2012, 107(2):245.
    • (2012) Basic Res Cardiol , vol.107 , Issue.2 , pp. 245
    • Lorenzen, J.M.1    Martino, F.2    Thum, T.3
  • 156
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • Balasubramanyam K., Varier R.A., Altaf M., Swaminathan V., Siddappa N.B., Ranga U., et al. Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem 2004, 279(49):51163-51171.
    • (2004) J Biol Chem , vol.279 , Issue.49 , pp. 51163-51171
    • Balasubramanyam, K.1    Varier, R.A.2    Altaf, M.3    Swaminathan, V.4    Siddappa, N.B.5    Ranga, U.6
  • 157
    • 79961175282 scopus 로고    scopus 로고
    • Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling
    • Xiao X., Shi D., Liu L., Wang J., Xie X., Kang T., et al. Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling. PLoS One 2011, 6(8):e22934.
    • (2011) PLoS One , vol.6 , Issue.8
    • Xiao, X.1    Shi, D.2    Liu, L.3    Wang, J.4    Xie, X.5    Kang, T.6
  • 158
    • 79960061626 scopus 로고    scopus 로고
    • Delphinidin, a specific inhibitor of histone acetyltransferase, suppresses inflammatory signaling via prevention of NF-kappaB acetylation in fibroblast-like synoviocyte MH7A cells
    • Seong A.R., Yoo J.Y., Choi K., Lee M.H., Lee Y.H., Lee J., et al. Delphinidin, a specific inhibitor of histone acetyltransferase, suppresses inflammatory signaling via prevention of NF-kappaB acetylation in fibroblast-like synoviocyte MH7A cells. Biochem Biophys Res Commun 2011, 410(3):581-586.
    • (2011) Biochem Biophys Res Commun , vol.410 , Issue.3 , pp. 581-586
    • Seong, A.R.1    Yoo, J.Y.2    Choi, K.3    Lee, M.H.4    Lee, Y.H.5    Lee, J.6
  • 159
    • 79551473225 scopus 로고    scopus 로고
    • Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor
    • Choi K.C., Park S., Lim B.J., Seong A.R., Lee Y.H., Shiota M., et al. Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor. Biochem J 2011, 433(1):235-244.
    • (2011) Biochem J , vol.433 , Issue.1 , pp. 235-244
    • Choi, K.C.1    Park, S.2    Lim, B.J.3    Seong, A.R.4    Lee, Y.H.5    Shiota, M.6
  • 160
    • 58349094740 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation
    • Choi K.C., Jung M.G., Lee Y.H., Yoon J.C., Kwon S.H., Kang H.B., et al. Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res 2009, 69(2):583-592.
    • (2009) Cancer Res , vol.69 , Issue.2 , pp. 583-592
    • Choi, K.C.1    Jung, M.G.2    Lee, Y.H.3    Yoon, J.C.4    Kwon, S.H.5    Kang, H.B.6
  • 161
    • 33847695362 scopus 로고    scopus 로고
    • Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity
    • Trivedi C.M., Luo Y., Yin Z., Zhang M., Zhu W., Wang T., et al. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat Med 2007, 13(3):324-331.
    • (2007) Nat Med , vol.13 , Issue.3 , pp. 324-331
    • Trivedi, C.M.1    Luo, Y.2    Yin, Z.3    Zhang, M.4    Zhu, W.5    Wang, T.6
  • 162
    • 34548269577 scopus 로고    scopus 로고
    • Feijoa sellowiana derived natural Flavone exerts anti-cancer action displaying HDAC inhibitory activities
    • Bontempo P., Mita L., Miceli M., Doto A., Nebbioso A., De Bellis F., et al. Feijoa sellowiana derived natural Flavone exerts anti-cancer action displaying HDAC inhibitory activities. Int J Biochem Cell Biol 2007, 39(10):1902-1914.
    • (2007) Int J Biochem Cell Biol , vol.39 , Issue.10 , pp. 1902-1914
    • Bontempo, P.1    Mita, L.2    Miceli, M.3    Doto, A.4    Nebbioso, A.5    De Bellis, F.6
  • 163
    • 84864354377 scopus 로고    scopus 로고
    • Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells
    • Pal-Bhadra M., Ramaiah M.J., Reddy T.L., Krishnan A., Pushpavalli S.N., Babu K.S., et al. Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells. BMC Cancer 2012, 12:180.
    • (2012) BMC Cancer , vol.12 , pp. 180
    • Pal-Bhadra, M.1    Ramaiah, M.J.2    Reddy, T.L.3    Krishnan, A.4    Pushpavalli, S.N.5    Babu, K.S.6
  • 164
    • 34547529740 scopus 로고    scopus 로고
    • Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera
    • Son I.H., Chung I.M., Lee S.I., Yang H.D., Moon H.I. Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera. Bioorg Med Chem Lett 2007, 17(17):4753-4755.
    • (2007) Bioorg Med Chem Lett , vol.17 , Issue.17 , pp. 4753-4755
    • Son, I.H.1    Chung, I.M.2    Lee, S.I.3    Yang, H.D.4    Moon, H.I.5
  • 165
    • 78650676828 scopus 로고    scopus 로고
    • Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells
    • Attoub S., Hassan A.H., Vanhoecke B., Iratni R., Takahashi T., Gaben A.M., et al. Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells. Eur J Pharmacol 2011, 651(1-3):18-25.
    • (2011) Eur J Pharmacol , vol.651 , Issue.1-3 , pp. 18-25
    • Attoub, S.1    Hassan, A.H.2    Vanhoecke, B.3    Iratni, R.4    Takahashi, T.5    Gaben, A.M.6
  • 166
    • 48649087037 scopus 로고    scopus 로고
    • Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon
    • Waldecker M., Kautenburger T., Daumann H., Busch C., Schrenk D. Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. J Nutr Biochem 2008, 19(9):587-593.
    • (2008) J Nutr Biochem , vol.19 , Issue.9 , pp. 587-593
    • Waldecker, M.1    Kautenburger, T.2    Daumann, H.3    Busch, C.4    Schrenk, D.5
  • 168
    • 34547786202 scopus 로고    scopus 로고
    • Artificial polymeric flavonoids: synthesis and applications
    • Uyama H. Artificial polymeric flavonoids: synthesis and applications. Macromol Biosci 2007, 7(4):410-422.
    • (2007) Macromol Biosci , vol.7 , Issue.4 , pp. 410-422
    • Uyama, H.1
  • 169
    • 0035825336 scopus 로고    scopus 로고
    • Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart
    • Lebeau J., Neviere R., Cotelle N. Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart. Bioorg Med Chem Lett 2001, 11(1):23-27.
    • (2001) Bioorg Med Chem Lett , vol.11 , Issue.1 , pp. 23-27
    • Lebeau, J.1    Neviere, R.2    Cotelle, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.