메뉴 건너뛰기




Volumn 109, Issue 6, 2010, Pages 1158-1171

Breviscapine protects against cardiac hypertrophy through blocking PKC-α-dependent signaling

Author keywords

Breviscapine; Cardiac hypertrophy; PKC ; SMAD

Indexed keywords

ANGIOTENSIN II; BREVISCAPINE; COLLAGEN; GLYCOGEN SYNTHASE KINASE 3BETA; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C ALPHA; TRITIUM;

EID: 77951700259     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22495     Document Type: Article
Times cited : (45)

References (41)
  • 1
    • 0032217267 scopus 로고    scopus 로고
    • IkappaB-NF-kappaB structures: At the interface of inflammation control
    • DOI 10.1016/S0092-8674(00)81694-3
    • Baeuerle PA. 1998. IkappaB-NF-kappaB structures: At the interface of inflammation control. Cell 95:729-731. (Pubitemid 29014451)
    • (1998) Cell , vol.95 , Issue.6 , pp. 729-731
    • Baeuerle, P.A.1
  • 3
    • 68149141041 scopus 로고    scopus 로고
    • Cellular repressor of E1A-stimulated genes attenuates cardiac hypertrophy and fibrosis
    • Bian Z, Cai J, Shen DF, Chen L, Yan L, Tang Q, Li H. 2009. Cellular repressor of E1A-stimulated genes attenuates cardiac hypertrophy and fibrosis. J Cell Mol Med 13:1302-1313.
    • (2009) J Cell Mol Med , vol.13 , pp. 1302-1313
    • Bian, Z.1    Cai, J.2    Shen, D.F.3    Chen, L.4    Yan, L.5    Tang, Q.6    Li, H.7
  • 4
    • 0037018154 scopus 로고    scopus 로고
    • PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)
    • Braz JC, Bueno OF, De Windt LJ, Molkentin JD. 2002. PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2). J Cell Biol 156:905-919.
    • (2002) J Cell Biol , vol.156 , pp. 905-919
    • Braz, J.C.1    Bueno, O.F.2    De Windt, L.J.3    Molkentin, J.D.4
  • 5
    • 0036843158 scopus 로고    scopus 로고
    • Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death
    • Bueno OF, Molkentin JD. 2002. Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death. Circ Res 91: 776-781.
    • (2002) Circ Res , vol.91 , pp. 776-781
    • Bueno, O.F.1    Molkentin, J.D.2
  • 7
    • 14644414790 scopus 로고    scopus 로고
    • Protein kinase cascades in the regulation of cardiac hypertrophy
    • DOI 10.1172/JCI200524178
    • Dorn GW II, Force T. 2005. Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest 115:527-537. (Pubitemid 40322222)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.3 , pp. 527-537
    • Dorn II, G.W.1    Force, T.2
  • 8
    • 23044435051 scopus 로고    scopus 로고
    • Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease
    • Epstein JA, Parmacek MS. 2005. Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease. Circulation 112:592-597.
    • (2005) Circulation , vol.112 , pp. 592-597
    • Epstein, J.A.1    Parmacek, M.S.2
  • 9
    • 0141682008 scopus 로고    scopus 로고
    • Angiotensin II induction of AP-1 in neurons requires stimulation of PI3-K and JNK
    • DOI 10.1016/j.bbrc.2003.09.047
    • Fleegal MA, Sumners C. 2003. Angiotensin II induction of AP-1 in neurons requires stimulation of PI3-K and JNK. Biochem Biophys Res Commun 310:470-477. (Pubitemid 37163688)
    • (2003) Biochemical and Biophysical Research Communications , vol.310 , Issue.2 , pp. 470-477
    • Fleegal, M.A.1    Sumners, C.2
  • 10
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • DOI 10.1038/nrm1983, PII NRM1983
    • Heineke J, Molkentin JD. 2006. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7:589-600. (Pubitemid 44325350)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.8 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 11
    • 0002565735 scopus 로고    scopus 로고
    • Signal transduction during cardiac hypertrophy: The role of Galpha(q), PLC betaI, and PKC
    • DOI 10.1016/S0008-6363(99)00211-4, PII S0008636399002114
    • Jalili T, Takeishi Y, Walsh RA. 1999. Signal transduction during cardiac hypertrophy: The role of G alpha q, PLC beta I, and PKC. Cardiovasc Res 44: 5-9. (Pubitemid 29431677)
    • (1999) Cardiovascular Research , vol.44 , Issue.1 , pp. 5-9
    • Jalili, T.1    Takeishi, Y.2    Walsh, R.A.3
  • 12
    • 0037143616 scopus 로고    scopus 로고
    • Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense
    • DOI 10.1161/01.CIR.0000030181.63741.56
    • Kagiyama S, Eguchi S, Frank GD, Inagami T, Zhang YC, Phillips MI. 2002. Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense. Circulation 106:909-912. (Pubitemid 34925322)
    • (2002) Circulation , vol.106 , Issue.8 , pp. 909-912
    • Kagiyama, S.1    Eguchi, S.2    Frank, G.D.3    Inagami, T.4    Zhang, Y.C.5    Phillips, M.I.6
  • 13
    • 39149119226 scopus 로고    scopus 로고
    • The intracellular renin-angiotensin system: Implications in cardiovascular remodeling
    • DOI 10.1097/MNH.0b013e3282f521a8, PII 0004155220080300000009
    • Kumar R, Singh VP, Baker KM. 2008. The intracellular renin-angiotensin system: Implications in cardiovascular remodeling. Curr Opin Nephrol Hypertens 17:168-173. (Pubitemid 351253042)
    • (2008) Current Opinion in Nephrology and Hypertension , vol.17 , Issue.2 , pp. 168-173
    • Kumar, R.1    Singh, V.P.2    Baker, K.M.3
  • 14
    • 9744230619 scopus 로고    scopus 로고
    • A study of the cardioprotective effect of breviscapine during hypoxia of cardiomyocytes
    • Li XL, Li YQ, Yan WM, Li HY, Xu H, Zheng XX, Guo DW, Tang LK. 2004. A study of the cardioprotective effect of breviscapine during hypoxia of cardiomyocytes. Planta Med 70:1039-1044.
    • (2004) Planta Med , vol.70 , pp. 1039-1044
    • Li, X.L.1    Li, Y.Q.2    Yan, W.M.3    Li, H.Y.4    Xu, H.5    Zheng, X.X.6    Guo, D.W.7    Tang, L.K.8
  • 17
    • 34249283088 scopus 로고    scopus 로고
    • Overexpression of myofibrillogenesis regulator-1 aggravates cardiac hypertrophy induced by angiotensin II in mice
    • DOI 10.1161/HYPERTENSIONAHA.106.085399
    • Li HL, She ZG, Li TB, Wang AB, Yang Q, Wei YS, Wang YG, Liu DP. 2007a. Overexpression of myofibrillogenesis regulator-1 aggravates cardiac hypertrophy induced by angiotensin II in mice. Hypertension 49:1399-1408. (Pubitemid 46809386)
    • (2007) Hypertension , vol.49 , Issue.6 , pp. 1399-1408
    • Li, H.-L.1    She, Z.-G.2    Li, T.-B.3    Wang, A.-B.4    Yang, Q.5    Wei, Y.-S.6    Wang, Y.-G.7    Liu, D.-P.8
  • 18
    • 34247106590 scopus 로고    scopus 로고
    • Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction
    • DOI 10.1161/CIRCULATIONAHA.106.656835
    • Li HL, Zhuo ML, Wang D, Wang AB, Cai H, Sun LH, Yang Q, Huang Y, Wei YS, Liu PP, Liu DP, Liang CC. 2007b. Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation 115:1885-1894. (Pubitemid 46598902)
    • (2007) Circulation , vol.115 , Issue.14 , pp. 1885-1894
    • Li, H.-L.1    Zhuo, M.-L.2    Wang, D.3    Wang, A.-B.4    Cai, H.5    Sun, L.-H.6    Yang, Q.7    Huang, Y.8    Wei, Y.-S.9    Liu, P.P.10    Liu, D.-P.11    Liang, C.-C.12
  • 19
    • 34548745874 scopus 로고    scopus 로고
    • Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats
    • DOI 10.1097/FJC.0b013e3180cbd0e7, PII 0000534420070900000016
    • Lin LL, Liu AJ, Liu JG, Yu XH, Qin LP, Su DF. 2007. Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats. J Cardiovasc Pharmacol 50:327-332. (Pubitemid 47428983)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.3 , pp. 327-332
    • Lin, L.-L.1    Liu, A.-J.2    Liu, J.-G.3    Yu, X.-H.4    Qin, L.-P.5    Su, D.-F.6
  • 20
    • 51249087928 scopus 로고    scopus 로고
    • Anti-inflammatory activity of the extracts and fractions from Erigeron multiradiatus through bioassay-guided procedures
    • Luo P, Zhang Z, Yi T, Zhang H, Liu X, Mo Z. 2008. Anti-inflammatory activity of the extracts and fractions from Erigeron multiradiatus through bioassay-guided procedures. J Ethnopharmacol 119:232-237.
    • (2008) J Ethnopharmacol , vol.119 , pp. 232-237
    • Luo, P.1    Zhang, Z.2    Yi, T.3    Zhang, H.4    Liu, X.5    Mo, Z.6
  • 21
    • 3042702881 scopus 로고    scopus 로고
    • Inflammatory cytokines and postmyocardial infarction remodeling
    • DOI 10.1161/01.RES.0000130526.20854.fa
    • Nian M, Lee P, Khaper N, Liu P. 2004. Inflammatory cytokines and post myocardial infarction remodeling. Circ Res 94:1543-1553. (Pubitemid 38856961)
    • (2004) Circulation Research , vol.94 , Issue.12 , pp. 1543-1553
    • Nian, M.1    Lee, P.2    Khaper, N.3    Liu, P.4
  • 22
    • 11144269771 scopus 로고    scopus 로고
    • PKC mediates cyclic stretch-induced cardiac hypertrophy through Rho family GTPases and mitogen-activated protein kinases in cardiomyocytes
    • DOI 10.1002/jcp.20151
    • Pan J, Singh US, Takahashi T, Oka Y, Palm-Leis A, Herbelin BS, Baker KM. 2005. PKC mediates cyclic stretch-induced cardiac hypertrophy through Rho family GTPases and mitogen-activated protein kinases in cardiomyocytes. J Cell Physiol 202:536-553. (Pubitemid 40041325)
    • (2005) Journal of Cellular Physiology , vol.202 , Issue.2 , pp. 536-553
    • Pan, J.1    Singh, U.S.2    Takahashi, T.3    Oka, Y.4    Palm-Leis, A.5    Herbelin, B.S.6    Baker, K.M.7
  • 23
    • 57349125036 scopus 로고    scopus 로고
    • Scutellarin-induced endothelium-independent relaxation in rat aorta
    • DOI 10.1002/ptr.2364
    • Pan Z, Feng T, Shan L, Cai B, Chu W, Niu H, Lu Y, Yang B. 2008. Scutellarin-induced endothelium-independent relaxation in rat aorta. Phytother Res 22:1428-1433. (Pubitemid 352789608)
    • (2008) Phytotherapy Research , vol.22 , Issue.11 , pp. 1428-1433
    • Pan, Z.1    Feng, T.2    Shan, L.3    Cai, B.4    Chu, W.5    Niu, H.6    Lu, Y.7    Yang, B.8
  • 24
    • 1542613386 scopus 로고    scopus 로고
    • Stress-activated MAP kinases in cardiac remodeling and heart failure: New insights from transgenic studies
    • DOI 10.1016/j.tcm.2003.11.002, PII S1050173803001920
    • Petrich BG, Wang Y. 2004. Stress-activated MAP kinases in cardiac remodeling and heart failure; New insights from transgenic studies. Trends Cardiovasc Med 14:50-55. (Pubitemid 38340846)
    • (2004) Trends in Cardiovascular Medicine , vol.14 , Issue.2 , pp. 50-55
    • Petrich, B.G.1    Wang, Y.2
  • 25
    • 3242793344 scopus 로고    scopus 로고
    • Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy
    • DOI 10.1016/j.cardiores.2004.02.003, PII S0008636304000793
    • Proud CG. 2004. Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy. Cardiovasc Res 63:403-413. (Pubitemid 38970184)
    • (2004) Cardiovascular Research , vol.63 , Issue.3 , pp. 403-413
    • Proud, C.G.1
  • 26
    • 34249326592 scopus 로고    scopus 로고
    • Is angiotensin II a direct mediator of left ventricular hypertrophy?
    • Reudelhuber TL, Bernstein KE, Delafontaine P. 2007. Is angiotensin II a direct mediator of left ventricular hypertrophy? Hypertension 49:1196-1201.
    • (2007) Hypertension , vol.49 , pp. 1196-1201
    • Reudelhuber, T.L.1    Bernstein, K.E.2    Delafontaine, P.3
  • 27
    • 0033735548 scopus 로고    scopus 로고
    • Angiotensin II induces nuclear factor-kappa B activation in cultured neonatal rat cardiomyocytes through protein kinase C signaling pathway
    • Rouet-Benzineb P, Gontero B, Dreyfus P, Lafuma C. 2000. Angiotensin II induces nuclear factor-kappa B activation in cultured neonatal rat cardiomyocytes through protein kinase C signaling pathway. J Mol Cell Cardiol 32:1767-1778.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 1767-1778
    • Rouet-Benzineb, P.1    Gontero, B.2    Dreyfus, P.3    Lafuma, C.4
  • 30
    • 0039791449 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes
    • Schonwasser DC, Marais RM, Marshall CJ, Parker PJ. 1998. Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes. Mol Cell Biol 18:790-798.
    • (1998) Mol Cell Biol , vol.18 , pp. 790-798
    • Schonwasser, D.C.1    Marais, R.M.2    Marshall, C.J.3    Parker, P.J.4
  • 31
    • 33845711358 scopus 로고    scopus 로고
    • Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway
    • DOI 10.1101/gad.1492806
    • Shiojima I, Walsh K. 2006. Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway. Genes Dev 20:3347-3365. (Pubitemid 44969154)
    • (2006) Genes and Development , vol.20 , Issue.24 , pp. 3347-3365
    • Shiojima, I.1    Walsh, K.2
  • 32
    • 60549104999 scopus 로고    scopus 로고
    • Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling
    • Tang Q, Cai J, Shen D, Bian Z, Yan L, Wang YX, Lan J, Zhuang GQ, Ma WZ, Wang W. 2009. Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling. J Mol Med 87:249-260.
    • (2009) J Mol Med , vol.87 , pp. 249-260
    • Tang, Q.1    Cai, J.2    Shen, D.3    Bian, Z.4    Yan, L.5    Wang, Y.X.6    Lan, J.7    Zhuang, G.Q.8    Ma, W.Z.9    Wang, W.10
  • 33
    • 0029789967 scopus 로고    scopus 로고
    • Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf
    • DOI 10.1074/jbc.271.38.23512
    • Ueda Y, Hirai S, Osada S, Suzuki A, Mizuno K, Ohno S. 1996. Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J Biol Chem 271:23512-23519. (Pubitemid 26314803)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.38 , pp. 23512-23519
    • Ueda, Y.1    Hirai, S.-I.2    Osada, S.-I.3    Suzuki, A.4    Mizuno, K.5    Ohno, S.6
  • 35
    • 34250303950 scopus 로고    scopus 로고
    • Prevention of early liver injury by breviscapine in streptozotocin- induced diabetic rats
    • DOI 10.1055/s-2007-967182
    • Wu YG, Xia LL, Lin H, Zhou D, Qian H, Lin ST. 2007. Prevention of early liver injury by breviscapine in streptozotocin-induced diabetic rats. Planta Med 73:433-438. (Pubitemid 46917457)
    • (2007) Planta Medica , vol.73 , Issue.5 , pp. 433-438
    • Wu, Y.-G.1    Xia, L.-L.2    Lin, H.3    Zhou, D.4    Qian, H.5    Lin, S.-T.6
  • 37
    • 34848828498 scopus 로고    scopus 로고
    • Effects of scutellarin on PKCgamma in PC12 cell injury induced by oxygen and glucose deprivation
    • DOI 10.1111/j.1745-7254.2007.00502.x
    • Xu W, Zha RP, Wang WY, Wang YP. 2007. Effects of scutellarin on PKCgamma in PC12 cell injury induced by oxygen and glucose deprivation. Acta Pharmacol Sin 28:1573-1579. (Pubitemid 47493275)
    • (2007) Acta Pharmacologica Sinica , vol.28 , Issue.10 , pp. 1573-1579
    • Xu, W.1    Zha, R.-P.2    Wang, W.-Y.3    Wang, Y.-P.4
  • 38
    • 37849041374 scopus 로고    scopus 로고
    • Breviscapine alleviates hepatic injury and inhibits PKC-mRNA and its protein expression in brain-dead BA-Ma mini pigs
    • Zhang SJ, Song Y, Zhai WL, Shi JH, Feng LS, Zhao YF, Chen S. 2007. Breviscapine alleviates hepatic injury and inhibits PKC-mRNA and its protein expression in brain-dead BA-Ma mini pigs. Hepatobiliary Pancreat Dis Int 6:604-609.
    • (2007) Hepatobiliary Pancreat Dis Int , vol.6 , pp. 604-609
    • Zhang, S.J.1    Song, Y.2    Zhai, W.L.3    Shi, J.H.4    Feng, L.S.5    Zhao, Y.F.6    Chen, S.7
  • 39
    • 0026576774 scopus 로고
    • Effect of new-breviscapine on fibrinolysis and anticoagulation of human vascular endothelial cells
    • Zhou QS, Zhao YM, Bai X, Li PX, Ruan CG. 1992. Effect of new-breviscapine on fibrinolysis and anticoagulation of human vascular endothelial cells. Acta Pharmacol Sin 13:239-242.
    • (1992) Acta Pharmacol Sin , vol.13 , pp. 239-242
    • Zhou, Q.S.1    Zhao, Y.M.2    Bai, X.3    Li, P.X.4    Ruan, C.G.5
  • 40
    • 0036205019 scopus 로고    scopus 로고
    • Ventricular remodeling by Scutellarein treatment in spontaneously hypertensive rats
    • Zhou J, Lei H, Chen Y, Li F, Ma C. 2002. Ventricular remodeling by Scutellarein treatment in spontaneously hypertensive rats. Chin Med J 115:375-377. (Pubitemid 34272436)
    • (2002) Chinese Medical Journal , vol.115 , Issue.3 , pp. 375-377
    • Wang, Z.1    Zou, J.2    Huang, Y.3    Cao, K.4    Xu, Y.5    Joseph, M.W.6
  • 41
    • 45849153507 scopus 로고    scopus 로고
    • Scutellarin induced Ca(2+) release and blocked KCl-induced Ca(2+) influx in smooth muscle cells isolated from rat thoracic artery
    • Zhu BH, Ma L, Pan XD, Huang YL, Liu J. 2008. Scutellarin induced Ca(2+) release and blocked KCl-induced Ca(2+) influx in smooth muscle cells isolated from rat thoracic artery. J Asian Nat Prod Res 10:583-589.
    • (2008) J Asian Nat Prod Res , vol.10 , pp. 583-589
    • Zhu, B.H.1    Ma, L.2    Pan, X.D.3    Huang, Y.L.4    Liu, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.