-
1
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011; 147:728-741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
2
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451:1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
3
-
-
84892859905
-
Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
-
Rogov V, Dötsch V, Johansen T, Kirkin V. Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol Cell 2014; 53:167-178.
-
(2014)
Mol Cell
, vol.53
, pp. 167-178
-
-
Rogov, V.1
Dötsch, V.2
Johansen, T.3
Kirkin, V.4
-
4
-
-
84878943669
-
The mechanism and physiological function of macroautophagy
-
Klionsky DJ, Codogno P. The mechanism and physiological function of macroautophagy. J Innate Immun 2013; 5:427-433.
-
(2013)
J Innate Immun
, vol.5
, pp. 427-433
-
-
Klionsky, D.J.1
Codogno, P.2
-
6
-
-
84880376355
-
Emerging regulation and functions of autophagy
-
Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol 2013; 15:713-720.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 713-720
-
-
Boya, P.1
Reggiori, F.2
Codogno, P.3
-
7
-
-
84886797274
-
Autophagy in infection, inflammation and immunity
-
Deretic V, Saitoh T, Akira S. Autophagy in infection, inflammation and immunity. Nat Rev Immunol 2013; 13:722-737.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
8
-
-
84877628647
-
Autophagy in human health and disease
-
Choi AM, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med 2013; 368:651-662.
-
(2013)
N Engl J Med
, vol.368
, pp. 651-662
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
9
-
-
84866122688
-
Autophagy modulation as a potential therapeutic target for diverse diseases
-
Rubinsztein DC, Codogno P, Levine B. Autophagy modulation as a potential therapeutic target for diverse diseases. Nat Rev Drug Discov 2012; 11:709-730.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 709-730
-
-
Rubinsztein, D.C.1
Codogno, P.2
Levine, B.3
-
10
-
-
84892166326
-
Role of autophagy in cancer prevention, development and therapy
-
Helgason GV, Holyoake TL, Ryan KM. Role of autophagy in cancer prevention, development and therapy. Essays Biochem 2013; 55:133-151.
-
(2013)
Essays Biochem
, vol.55
, pp. 133-151
-
-
Helgason, G.V.1
Holyoake, T.L.2
Ryan, K.M.3
-
11
-
-
84882254367
-
The role of autophagy in neurodegenerative disease
-
Nixon RA. The role of autophagy in neurodegenerative disease. Nat Med 2013; 19:983-997.
-
(2013)
Nat Med
, vol.19
, pp. 983-997
-
-
Nixon, R.A.1
-
13
-
-
84895930872
-
Liver autophagy: Much more than just taking out the trash
-
Schneider JL, Cuervo AM. Liver autophagy: much more than just taking out the trash. Nat Rev Gastroenterol Hepatol 2013; 11:187-200.
-
(2013)
Nat Rev Gastroenterol Hepatol
, vol.11
, pp. 187-200
-
-
Schneider, J.L.1
Cuervo, A.M.2
-
14
-
-
84892613717
-
Autophagy in kidney health and disease
-
Wang Z, Choi ME. Autophagy in kidney health and disease. Antioxid Redox Signal 2014; 20:519-537.
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 519-537
-
-
Wang, Z.1
Choi, M.E.2
-
15
-
-
84885580133
-
Cardiovascular autophagy: Concepts, controversies and perspectives
-
[Epub ahead of print] Summary overview on the possible functions of autophagy in cardiac homeostasis and disease
-
Lavandero S, Troncoso R, Rothermel BA, et al. Cardiovascular autophagy: concepts, controversies and perspectives. Autophagy 2013; 9:1455-1466. [Epub ahead of print] Summary overview on the possible functions of autophagy in cardiac homeostasis and disease.
-
(2013)
Autophagy
, vol.9
, pp. 1455-1466
-
-
Lavandero, S.1
Troncoso, R.2
Rothermel, B.A.3
-
16
-
-
17044440789
-
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)
-
Nishino I, Fu J, Tanji K, et al. Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature 2000; 406:906-910.
-
(2000)
Nature
, vol.406
, pp. 906-910
-
-
Nishino, I.1
Fu, J.2
Tanji, K.3
-
17
-
-
0023832274
-
X-linked myopathy with excessive autophagy: A new hereditary muscle disease
-
Kalimo H, Savontaus ML, Lang H, et al. X-linked myopathy with excessive autophagy: a new hereditary muscle disease. Ann Neurol 1988; 23:258-265.
-
(1988)
Ann Neurol
, vol.23
, pp. 258-265
-
-
Kalimo, H.1
Savontaus, M.L.2
Lang, H.3
-
18
-
-
84902242103
-
Autophagy dysfunction and its link to Alzheimers disease and Type II diabetes mellitus
-
[Epub ahead of print]
-
Wilson CM, Magnaudeix A, Yardin C, Terro F. Autophagy dysfunction and its link to Alzheimers disease and Type II diabetes mellitus. CNS Neurol Disord Drug Targets 2013; 13:226-246. [Epub ahead of print]
-
(2013)
CNS Neurol Disord Drug Targets
, vol.13
, pp. 226-246
-
-
Wilson, C.M.1
Magnaudeix, A.2
Yardin, C.3
Terro, F.4
-
19
-
-
84877331888
-
Autophagy regulates inflammation following oxidative injury in diabetes
-
Wang Y, Li YB, Yin JJ, et al. Autophagy regulates inflammation following oxidative injury in diabetes. Autophagy 2013; 9:272-277.
-
(2013)
Autophagy
, vol.9
, pp. 272-277
-
-
Wang, Y.1
Li, Y.B.2
Yin, J.J.3
-
20
-
-
84899929877
-
The interplay between autophagy and apoptosis in the diabetic heart
-
Ouyang C, You J, Xie Z. The interplay between autophagy and apoptosis in the diabetic heart. J Mol Cell Cardiol 2013; 71C:71-80.
-
(2013)
J Mol Cell Cardiol
, vol.71
, pp. 71-80
-
-
Ouyang, C.1
You, J.2
Xie, Z.3
-
21
-
-
84873436219
-
Autophagy: Emerging roles in lipid homeostasis and metabolic control
-
Christian P, Sacco J, Adeli K. Autophagy: Emerging roles in lipid homeostasis and metabolic control. Biochim Biophys Acta 2013; 1831:819-824.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 819-824
-
-
Christian, P.1
Sacco, J.2
Adeli, K.3
-
22
-
-
84893714992
-
Autophagy in aging and neurodegenerative diseases: Implications for pathogenesis and therapy
-
Tan CC, Yu JT, Tan MS, et al. Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy. Neurobiol Aging 2014; 35:941-957.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 941-957
-
-
Tan, C.C.1
Yu, J.T.2
Tan, M.S.3
-
25
-
-
84892569830
-
An overview of autophagy: Morphology, mechanism, and regulation
-
Parzych KR, Klionsky DJ. An overview of autophagy: morphology, mechanism, and regulation. Antioxid Redox Signal 2014; 20:460-473.
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 460-473
-
-
Parzych, K.R.1
Klionsky, D.J.2
-
26
-
-
84862908818
-
AMPK and mTOR in cellular energy homeostasis and drug targets
-
Inoki K, Kim J, Guan KL. AMPK and mTOR in cellular energy homeostasis and drug targets. Annu Rev Pharmacol Toxicol 2012; 52:381-400.
-
(2012)
Annu Rev Pharmacol Toxicol
, vol.52
, pp. 381-400
-
-
Inoki, K.1
Kim, J.2
Guan, K.L.3
-
27
-
-
84856800302
-
Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: Cross talk, shortcuts, and feedbacks
-
Alers S, Löffler AS, Wesselborg S, Stork B. Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks. Mol Cell Biol 2012; 32:2-11.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2-11
-
-
Alers, S.1
Löffler, A.S.2
Wesselborg, S.3
Stork, B.4
-
28
-
-
84873675067
-
The ULK1 complex: Sensing nutrient signals for autophagy activation
-
Wong PM, Puente C, Ganley IG, Jiang X. The ULK1 complex: sensing nutrient signals for autophagy activation. Autophagy 2013; 9:124-137.
-
(2013)
Autophagy
, vol.9
, pp. 124-137
-
-
Wong, P.M.1
Puente, C.2
Ganley, I.G.3
Jiang, X.4
-
29
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-Activated protein kinase connects energy sensing to mitophagy
-
Egan DF, Shackelford DB, Mihaylova MM, et al. Phosphorylation of ULK1 (hATG1) by AMP-Activated protein kinase connects energy sensing to mitophagy. Science 2011; 331:456-461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
-
30
-
-
77951237303
-
The Beclin 1 interactome
-
He C, Levine B. The Beclin 1 interactome. Curr Opin Cell Biol 2010; 22:140-149.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 140-149
-
-
He, C.1
Levine, B.2
-
31
-
-
77957728513
-
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
-
Di Bartolomeo S, Corazzari M, Nazio F, et al. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. J Cell Biol 2010; 191:155-168.
-
(2010)
J Cell Biol
, vol.191
, pp. 155-168
-
-
Di Bartolomeo, S.1
Corazzari, M.2
Nazio, F.3
-
32
-
-
84880331368
-
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
-
Russell RC, Tian Y, Yuan H, et al. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat Cell Biol 2013; 15:741-750.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 741-750
-
-
Russell, R.C.1
Tian, Y.2
Yuan, H.3
-
33
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E. Autophagy and metabolism. Science 2010; 330:1344-1348.
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
34
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Mariño G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40:280-293.
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Mariño, G.2
Levine, B.3
-
35
-
-
79955949858
-
The elimination of accumulated and aggregated proteins: A role for aggrephagy in neurodegeneration
-
Yamamoto A, Simonsen A. The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration. Neurobiol Dis 2011; 43:17-28.
-
(2011)
Neurobiol Dis
, vol.43
, pp. 17-28
-
-
Yamamoto, A.1
Simonsen, A.2
-
36
-
-
84861082440
-
The many faces of mitochondrial autophagy: Making sense of contrasting observations in recent research
-
May AI, Devenish RJ, Prescott M. The many faces of mitochondrial autophagy: making sense of contrasting observations in recent research. Int J Cell Biol 2012; 2012:431684.
-
(2012)
Int J Cell Biol 2012
, pp. 431684
-
-
May, A.I.1
Devenish, R.J.2
Prescott, M.3
-
38
-
-
17844365594
-
Genetics of Parkinsons disease
-
Morris HR. Genetics of Parkinsons disease. Ann Med 2005; 37:86-96.
-
(2005)
Ann Med
, vol.37
, pp. 86-96
-
-
Morris, H.R.1
-
39
-
-
84887486172
-
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
-
Jin SM, Youle RJ. The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 2013; 9:1750-1757.
-
(2013)
Autophagy
, vol.9
, pp. 1750-1757
-
-
Jin, S.M.1
Youle, R.J.2
-
40
-
-
84883414890
-
The LIR motif-crucial for selective autophagy
-
Birgisdottir A B, Lamark T, Johansen T. The LIR motif-crucial for selective autophagy. J Cell Sci 2013; 126:3237-3247.
-
(2013)
J Cell Sci
, vol.126
, pp. 3237-3247
-
-
Birgisdottir, A.B.1
Lamark, T.2
Johansen, T.3
-
41
-
-
84894053505
-
Autophagy and pancreatic b-cells
-
Mazza S, Maffucci T. Autophagy and pancreatic b-cells. Vitam Horm 2014; 95:145-164.
-
(2014)
Vitam Horm
, vol.95
, pp. 145-164
-
-
Mazza, S.1
Maffucci, T.2
-
42
-
-
84863258890
-
Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic b-cells
-
Quan W, Lim YM, Lee MS. Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic b-cells. Exp Mol Med 2012; 44:81-88.
-
(2012)
Exp Mol Med
, vol.44
, pp. 81-88
-
-
Quan, W.1
Lim, Y.M.2
Lee, M.S.3
-
43
-
-
52749094770
-
Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia
-
Jung HS, Chung KW, Won Kim J, et al. Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. Cell Metab 2008; 8:318-324.
-
(2008)
Cell Metab
, vol.8
, pp. 318-324
-
-
Jung, H.S.1
Chung, K.W.2
Won Kim, J.3
-
44
-
-
84875416620
-
Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes
-
Bachar-Wikstrom E, Wikstrom JD, Ariav Y, et al. Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes. Diabetes 2013; 62:1227-1237.
-
(2013)
Diabetes
, vol.62
, pp. 1227-1237
-
-
Bachar-Wikstrom, E.1
Wikstrom, J.D.2
Ariav, Y.3
-
45
-
-
84893744708
-
The role of autophagy in the pathogenesis of diabetic nephropathy
-
Yamahara K, Yasuda M, Kume S, et al. The role of autophagy in the pathogenesis of diabetic nephropathy. J Diabetes Res 2013; 2013:193757.
-
(2013)
J Diabetes Res 2013
, pp. 193757
-
-
Yamahara, K.1
Yasuda, M.2
Kume, S.3
-
46
-
-
84876117324
-
Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury
-
Fang L, Zhou Y, Cao H, et al. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS One 2013; 8:e60546.
-
(2013)
PLoS One
, vol.8
-
-
Fang, L.1
Zhou, Y.2
Cao, H.3
-
47
-
-
84875258906
-
High glucose induces autophagy in podocytes
-
Ma T, Zhu J, Chen X, et al. High glucose induces autophagy in podocytes. Exp Cell Res 2013; 319:779-789.
-
(2013)
Exp Cell Res
, vol.319
, pp. 779-789
-
-
Ma, T.1
Zhu, J.2
Chen, X.3
-
48
-
-
84870580153
-
Autophagy in proximal tubules protects against acute kidney injury
-
Jiang M, Wei Q, Dong G, et al. Autophagy in proximal tubules protects against acute kidney injury. Kidney Int 2012; 82:1271-1283.
-
(2012)
Kidney Int
, vol.82
, pp. 1271-1283
-
-
Jiang, M.1
Wei, Q.2
Dong, G.3
-
49
-
-
84887070613
-
Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions
-
Yamahara K, Kume S, Koya D, et al. Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions. J Am Soc Nephrol 2013; 24:1769-1781
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 1769-1781
-
-
Yamahara, K.1
Kume, S.2
Koya, D.3
-
50
-
-
84876220612
-
Regulation of interplay between autophagy and apoptosis in the diabetic heart: New role of AMPK
-
Zou MH, Xie Z. Regulation of interplay between autophagy and apoptosis in the diabetic heart: new role of AMPK. Autophagy 2013; 9:624-625.
-
(2013)
Autophagy
, vol.9
, pp. 624-625
-
-
Zou, M.H.1
Xie, Z.2
-
51
-
-
80053393865
-
AMP-Activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy
-
Xie Z, He C, Zou MH. AMP-Activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy. Autophagy 2011; 7:1254-1255.
-
(2011)
Autophagy
, vol.7
, pp. 1254-1255
-
-
Xie, Z.1
He, C.2
Zou, M.H.3
-
52
-
-
79959385996
-
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
-
Xie Z, Lau K, Eby B, et al. Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes 2011; 60:1770-1778.
-
(2011)
Diabetes
, vol.60
, pp. 1770-1778
-
-
Xie, Z.1
Lau, K.2
Eby, B.3
-
53
-
-
84875450015
-
Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
-
He C, Zhu H, Li H, et al. Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes. Diabetes 2013; 62:1270-1281.
-
(2013)
Diabetes
, vol.62
, pp. 1270-1281
-
-
He, C.1
Zhu, H.2
Li, H.3
-
54
-
-
84884562299
-
Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy
-
Zhao Y, Zhang L, Qiao Y, et al. Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy. PLoS One 2013; 8:e75927.
-
(2013)
PLoS One
, vol.8
-
-
Zhao, Y.1
Zhang, L.2
Qiao, Y.3
-
55
-
-
84880065357
-
Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes
-
Xu X, Kobayashi S, Chen K, et al. Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes. J Biol Chem 2013; 288:18077-18092.
-
(2013)
J Biol Chem
, vol.288
, pp. 18077-18092
-
-
Xu, X.1
Kobayashi, S.2
Chen, K.3
-
56
-
-
84885543075
-
Myocardial glycophagy -A specific glycogen handling response to metabolic stress is accentuated in the female heart
-
Reichelt ME, Mellor KM, Curl CL, et al. Myocardial glycophagy -a specific glycogen handling response to metabolic stress is accentuated in the female heart. J Mol Cell Cardiol 2013; 65:67-75.
-
(2013)
J Mol Cell Cardiol
, vol.65
, pp. 67-75
-
-
Reichelt, M.E.1
Mellor, K.M.2
Curl, C.L.3
-
57
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
Wen H, Gris D, Lei Y, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol 2011; 12:408-415.
-
(2011)
Nat Immunol
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
-
58
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 2011; 12:222-230.
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
-
59
-
-
79955006431
-
Dampening insulin signaling by an NLRP3 metaflammasome
-
Choi AM, Nakahira K. Dampening insulin signaling by an NLRP3 metaflammasome. Nat Immunol 2011; 12:379-380.
-
(2011)
Nat Immunol
, vol.12
, pp. 379-380
-
-
Choi, A.M.1
Nakahira, K.2
-
60
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
Singh R, Kaushik S, Wang Y, et al. Autophagy regulates lipid metabolism. Nature 2009; 458:1131-1135.
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
Kaushik, S.2
Wang, Y.3
-
61
-
-
84859768059
-
Lipophagy: Connecting autophagy and lipid metabolism
-
Singh R, Cuervo AM. Lipophagy: connecting autophagy and lipid metabolism. Int J Cell Biol 2012; 2012:282041.
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 282041
-
-
Singh, R.1
Cuervo, A.M.2
-
62
-
-
77956400005
-
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
-
Yang L, Li P, Fu S, et al. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab 2010; 11:467-478.
-
(2010)
Cell Metab
, vol.11
, pp. 467-478
-
-
Yang, L.1
Li, P.2
Fu, S.3
-
63
-
-
84872057896
-
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
-
Kim KH, Jeong YT, Oh H, et al. Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med 2013; 19:83-92.
-
(2013)
Nat Med
, vol.19
, pp. 83-92
-
-
Kim, K.H.1
Jeong, Y.T.2
Oh, H.3
-
64
-
-
84877611062
-
The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue
-
Kosacka J, Koch K, Gericke M, et al. The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue. Diabetol Metab Syndr 2013; 5:23.
-
(2013)
Diabetol Metab Syndr
, vol.5
, pp. 23
-
-
Kosacka, J.1
Koch, K.2
Gericke, M.3
-
65
-
-
73949124173
-
Adipose-specific deletion of autophagyrelated gene 7 (atg7) in mice reveals a role in adipogenesis
-
Zhang Y, Goldman S, Baerga R, et al. Adipose-specific deletion of autophagyrelated gene 7 (atg7) in mice reveals a role in adipogenesis. Proc Natl Acad Sci U S A 2009; 106:19860-19865.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19860-19865
-
-
Zhang, Y.1
Goldman, S.2
Baerga, R.3
-
66
-
-
70449448312
-
Autophagy regulates adipose mass and differentiation in mice
-
Singh R, Xiang Y, Wang Y, et al. Autophagy regulates adipose mass and differentiation in mice. J Clin Invest 2009; 119:3329-3339.
-
(2009)
J Clin Invest
, vol.119
, pp. 3329-3339
-
-
Singh, R.1
Xiang, Y.2
Wang, Y.3
-
67
-
-
84883488843
-
Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development
-
Martinez-Lopez N, Athonvarangkul D, Sahu S, et al. Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development. EMBO Rep 2013; 14:795-803.
-
(2013)
EMBO Rep
, vol.14
, pp. 795-803
-
-
Martinez-Lopez, N.1
Athonvarangkul, D.2
Sahu, S.3
-
68
-
-
84867249241
-
Exercise induces autophagy in peripheral tissues and in the brain
-
He C, Sumpter R Jr, Levine B. Exercise induces autophagy in peripheral tissues and in the brain. Autophagy 2012; 8:1548-1551.
-
(2012)
Autophagy
, vol.8
, pp. 1548-1551
-
-
He, C.1
Sumpter Jr., R.2
Levine, B.3
-
69
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
He C, Bassik MC, Moresi V, et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 2012; 481:511-515.
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
Bassik, M.C.2
Moresi, V.3
-
70
-
-
79960951346
-
Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance
-
Kaushik S, Rodriguez-Navarro JA, Arias E, et al. Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance. Cell Metab 2011; 14:173-183.
-
(2011)
Cell Metab
, vol.14
, pp. 173-183
-
-
Kaushik, S.1
Rodriguez-Navarro, J.A.2
Arias, E.3
-
71
-
-
84856213604
-
Autophagy and mitochondria in Pompe disease: Nothing is so new as what has long been forgotten
-
Raben N, Wong A, Ralston E, Myerowitz R. Autophagy and mitochondria in Pompe disease: nothing is so new as what has long been forgotten. Am J Med Genet C Semin Med Genet 2012; 160C:13-21.
-
(2012)
Am J Med Genet C Semin Med Genet
, vol.160
, pp. 13-21
-
-
Raben, N.1
Wong, A.2
Ralston, E.3
Myerowitz, R.4
-
72
-
-
84893192369
-
Glycogenosome accumulation in the arrector pili muscle in Pompe disease
-
doi:10.1186/ 1750-1172-9-17
-
Katona I, Weis J, Hanisch F. Glycogenosome accumulation in the arrector pili muscle in Pompe disease. Orphanet J Rare Dis 2014; 9:17. doi:10.1186/ 1750-1172-9-17.
-
(2014)
Orphanet J Rare Dis
, vol.9
, Issue.17
-
-
Katona, I.1
Weis, J.2
Hanisch, F.3
-
73
-
-
84869439058
-
Impaired autophagy contributes to muscle atrophy in glycogen storage disease type II patients
-
Nascimbeni AC, Fanin M, Masiero E, et al. Impaired autophagy contributes to muscle atrophy in glycogen storage disease type II patients. Autophagy 2012; 8:1697-1700.
-
(2012)
Autophagy
, vol.8
, pp. 1697-1700
-
-
Nascimbeni, A.C.1
Fanin, M.2
Masiero, E.3
-
74
-
-
84866082112
-
The role of autophagy in the pathogenesis of glycogen storage disease type II (GSDII)
-
Nascimbeni AC, Fanin M, Masiero E, et al. The role of autophagy in the pathogenesis of glycogen storage disease type II (GSDII). Cell Death Differ 2012; 19:1698-1708.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1698-1708
-
-
Nascimbeni, A.C.1
Fanin, M.2
Masiero, E.3
-
75
-
-
84879072520
-
Skeletal muscle pathology of infantile Pompe disease during long-Term enzyme replacement therapy
-
Prater SN, Patel TT, Buckley AF, et al. Skeletal muscle pathology of infantile Pompe disease during long-Term enzyme replacement therapy. Orphanet J Rare Dis 2013; 8:90.
-
(2013)
Orphanet J Rare Dis
, vol.8
, pp. 90
-
-
Prater, S.N.1
Patel, T.T.2
Buckley, A.F.3
-
76
-
-
78649288882
-
Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disordermurine Pompe disease
-
Raben N, Schreiner C, Baum R, et al. Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disordermurine Pompe disease. Autophagy 2010; 6:1078-1089.
-
(2010)
Autophagy
, vol.6
, pp. 1078-1089
-
-
Raben, N.1
Schreiner, C.2
Baum, R.3
-
77
-
-
84893055506
-
The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris
-
Martina JA, Diab HI, Lishu L, et al. The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris. Sci Signal 2014; 7-9.
-
Sci Signal
, vol.2014
, pp. 7-9
-
-
Martina, J.A.1
Diab, H.I.2
Lishu, L.3
-
78
-
-
84877601173
-
Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease
-
Spampanato C, Feeney E, Li L, et al. Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease. EMBO Mol Med 2013; 5:691-706.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 691-706
-
-
Spampanato, C.1
Feeney, E.2
Li, L.3
-
79
-
-
84891741302
-
Chaperone-mediated autophagy: Roles in disease and aging
-
Cuervo AM, Wong E. Chaperone-mediated autophagy: roles in disease and aging. Cell Res 2014; 24:92-104.
-
(2014)
Cell Res
, vol.24
, pp. 92-104
-
-
Cuervo, A.M.1
Wong, E.2
-
80
-
-
84878691312
-
Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease
-
Nemazanyy I, Blaauw B, Paolini C, et al. Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease. EMBO Mol Med 2013; 5:870-890.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 870-890
-
-
Nemazanyy, I.1
Blaauw, B.2
Paolini, C.3
-
81
-
-
84902544797
-
Late-Adult onset of X-linked myopathy with excessive autophagy (XMEA)
-
doi: 10.1002/mus.24197. [Epub ahead of print]
-
Crockett CD, Ruggieri A, Gujrati M, et al. Late-Adult onset of X-linked myopathy with excessive autophagy (XMEA). Muscle Nerve 2014. doi: 10.1002/mus.24197. [Epub ahead of print]
-
(2014)
Muscle Nerve
-
-
Crockett, C.D.1
Ruggieri, A.2
Gujrati, M.3
-
82
-
-
84876840432
-
VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy
-
Ramachandran N, Munteanu I, Wang P, et al. VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy. Acta Neuropathol 2013; 125:439-457.
-
(2013)
Acta Neuropathol
, vol.125
, pp. 439-457
-
-
Ramachandran, N.1
Munteanu, I.2
Wang, P.3
-
83
-
-
84867021889
-
The homozygote VCP(R155H/ R155H) mouse model exhibits accelerated human VCP-Associated disease pathology
-
Nalbandian A, Llewellyn KJ, Kitazawa M, et al. The homozygote VCP(R155H/ R155H) mouse model exhibits accelerated human VCP-Associated disease pathology. PLoS One 2012; 7:e46308.
-
(2012)
PLoS One
, vol.7
-
-
Nalbandian, A.1
Llewellyn, K.J.2
Kitazawa, M.3
-
84
-
-
84859423325
-
Pagets disease of bone: Evidence for complex pathogenetic interactions
-
Chung PY, Van Hul W. Pagets disease of bone: evidence for complex pathogenetic interactions. Semin Arthritis Rheum 2012; 41:619-641.
-
(2012)
Semin Arthritis Rheum
, vol.41
, pp. 619-641
-
-
Chung, P.Y.1
Van Hul, W.2
-
85
-
-
84884271969
-
New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Pagets disease of bone
-
Rea SL, Walsh JP, Layfield R, et al. New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Pagets disease of bone. Endocr Rev 2013; 34:501-524.
-
(2013)
Endocr Rev
, vol.34
, pp. 501-524
-
-
Rea, S.L.1
Walsh, J.P.2
Layfield, R.3
-
86
-
-
84883830467
-
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy
-
Ichimura Y, Waguri S, Sou YS, et al. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol Cell 2013; 51:618-631.
-
(2013)
Mol Cell
, vol.51
, pp. 618-631
-
-
Ichimura, Y.1
Waguri, S.2
Sou, Y.S.3
-
87
-
-
84874712704
-
Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-Antitrypsin deficiency
-
Pastore N, Blomenkamp K, Annunziata F, et al. Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-Antitrypsin deficiency. EMBO Mol Med 2013; 5:397-412.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 397-412
-
-
Pastore, N.1
Blomenkamp, K.2
Annunziata, F.3
-
88
-
-
53749087325
-
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
-
Chen ZH, Kim HP, Sciurba FC, et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One 2008; 3:e3316.
-
(2008)
PLoS One
, vol.3
-
-
Zh, C.1
Kim, H.P.2
Sciurba, F.C.3
|