Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

Nature Medicine

Volumn 19, Issue 1, 2013, Pages 83-92

  Kim, Kook Hwan ^a   Jeong, Yeon Taek ^a   Oh, Hyunhee ^b   Kim, Seong Hun ^a   Cho, Jae Min ^a   Kim, Yo Na ^b   Kim, Su Sung ^b   Kim, Do Hoon ^a   Hur, Kyu Yeon ^a   Kim, Hyoung Kyu ^c   Ko, Taehee ^c   Han, Jin ^c   Kim, Hong Lim ^d   Kim, Jin ^d   Back, Sung Hoon ^e   Komatsu, Masaaki ^f   Chen, Hsiuchen ^g   Chan, David C ^g   Konishi, Morichika ^h   Itoh, Nobuyuki ⁱ   Choi, Cheol Soo ^b   Lee, Myung Shik ^a   more..

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Gachon University College of Medicine   (South Korea)

^c Inje University College of Medicine   (South Korea)

^d The Catholic University of Korea   (South Korea)

^e University of Ulsan   (South Korea)

^f TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^g CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^h KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

ⁱ KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY RELATED 7; FIBROBLAST GROWTH FACTOR 21; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DIETARY INTAKE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FAT MASS; FATTY ACID OXIDATION; GENE DELETION; INSULIN RESISTANCE; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; MUSCLE MASS; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE;

ACTIVATING TRANSCRIPTION FACTOR 4; ADIPOSE TISSUE, WHITE; ANIMALS; AUTOPHAGY; DIET; ENERGY METABOLISM; FEMALE; FIBROBLAST GROWTH FACTORS; GENE DELETION; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; OBESITY; UP-REGULATION;

MUS;

EID: 84872057896     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3014     Document Type: Article

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