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Volumn 41, Issue 5, 2012, Pages 619-641

Paget's Disease of Bone: Evidence for Complex Pathogenetic Interactions

Author keywords

Bisphosphonates; OPG; Osteosarcoma; Paget's disease of bone; RANK; RANKL; SQSTM1; VCP; Virus

Indexed keywords

ALENDRONIC ACID; BINDING PROTEIN; BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; DENOSUMAB; ETIDRONIC ACID; IBANDRONIC ACID; PAMIDRONIC ACID; RISEDRONIC ACID; SEQUESTOME1; TILUDRONIC ACID; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN; ZOLEDRONIC ACID;

EID: 84859423325     PISSN: 00490172     EISSN: 1532866X     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2011.07.005     Document Type: Article
Times cited : (55)

References (265)
  • 1
    • 23444437430 scopus 로고    scopus 로고
    • Sir James Paget's research into medical education
    • McManus I.C. Sir James Paget's research into medical education. Lancet 2005, 366(9484):506-513.
    • (2005) Lancet , vol.366 , Issue.9484 , pp. 506-513
    • McManus, I.C.1
  • 2
    • 0036546729 scopus 로고    scopus 로고
    • Evidence of geographic variation in the occurrence of Paget's disease
    • Armas J.B., Pimentel F., Guyer P.B., Cooper C., Pye S.R., O'Neill T.W. Evidence of geographic variation in the occurrence of Paget's disease. Bone 2002, 30(4):649-650.
    • (2002) Bone , vol.30 , Issue.4 , pp. 649-650
    • Armas, J.B.1    Pimentel, F.2    Guyer, P.B.3    Cooper, C.4    Pye, S.R.5    O'Neill, T.W.6
  • 3
    • 0019745914 scopus 로고
    • The epidemiology of Paget's disease
    • Barker D.J. The epidemiology of Paget's disease. Metab Bone Dis Relat Res 1981, 3(4-5):231-233.
    • (1981) Metab Bone Dis Relat Res , vol.3 , Issue.4-5 , pp. 231-233
    • Barker, D.J.1
  • 6
    • 0036861114 scopus 로고    scopus 로고
    • Paget's disease in New Zealand: evidence for declining prevalence
    • Doyle T., Gunn J., Anderson G., Gill M., Cundy T. Paget's disease in New Zealand: evidence for declining prevalence. Bone 2002, 31(5):616-619.
    • (2002) Bone , vol.31 , Issue.5 , pp. 616-619
    • Doyle, T.1    Gunn, J.2    Anderson, G.3    Gill, M.4    Cundy, T.5
  • 8
    • 33749250010 scopus 로고    scopus 로고
    • Epidemiology of Paget's disease in Europe: the prevalence is decreasing
    • Poor G., Donath J., Fornet B., Cooper C. Epidemiology of Paget's disease in Europe: the prevalence is decreasing. J Bone Miner Res 2006, 21(10):1545-1549.
    • (2006) J Bone Miner Res , vol.21 , Issue.10 , pp. 1545-1549
    • Poor, G.1    Donath, J.2    Fornet, B.3    Cooper, C.4
  • 9
    • 0033827275 scopus 로고    scopus 로고
    • Long-term trends in the incidence of Paget's disease of bone
    • Tiegs R.D., Lohse C.M., Wollan P.C., Melton L.J. Long-term trends in the incidence of Paget's disease of bone. Bone 2000, 27(3):423-427.
    • (2000) Bone , vol.27 , Issue.3 , pp. 423-427
    • Tiegs, R.D.1    Lohse, C.M.2    Wollan, P.C.3    Melton, L.J.4
  • 11
    • 0023905760 scopus 로고
    • Paget's disease of bone in South Africa
    • Guyer P.B., Chamberlain A.T. Paget's disease of bone in South Africa. Clin Radiol 1988, 39(1):51-52.
    • (1988) Clin Radiol , vol.39 , Issue.1 , pp. 51-52
    • Guyer, P.B.1    Chamberlain, A.T.2
  • 12
    • 79959250857 scopus 로고    scopus 로고
    • Paget disease of the bone: Does it exist in Saudi Arabia?
    • Alshaikh O.M., Almanea H., Alzahrani A.S. Paget disease of the bone: Does it exist in Saudi Arabia?. Ann Saudi Med 2011, 31(3):305-310.
    • (2011) Ann Saudi Med , vol.31 , Issue.3 , pp. 305-310
    • Alshaikh, O.M.1    Almanea, H.2    Alzahrani, A.S.3
  • 13
    • 0028793565 scopus 로고
    • Paget's disease of bone in Negev Bedouin: report of two cases
    • Lowenthal M.N., Alkalay D., Abu Rabbia Y., Liel Y. Paget's disease of bone in Negev Bedouin: report of two cases. Isr J Med Sci 1995, 31(10):628-629.
    • (1995) Isr J Med Sci , vol.31 , Issue.10 , pp. 628-629
    • Lowenthal, M.N.1    Alkalay, D.2    Abu Rabbia, Y.3    Liel, Y.4
  • 14
    • 4444341829 scopus 로고    scopus 로고
    • Monostotic Paget's disease of the tibia in Korea
    • Lee C.H., Han S.H., Yoon B.Y., Lee Y.W. Monostotic Paget's disease of the tibia in Korea. Clin Rheumatol 2004, 23(4):381-382.
    • (2004) Clin Rheumatol , vol.23 , Issue.4 , pp. 381-382
    • Lee, C.H.1    Han, S.H.2    Yoon, B.Y.3    Lee, Y.W.4
  • 15
    • 33644874672 scopus 로고    scopus 로고
    • Paget's disease of the bone in a Chinese woman
    • H'Ng M.W., Ho Y.Y. Paget's disease of the bone in a Chinese woman. Australas Radiol 2005, 49(6):505-507.
    • (2005) Australas Radiol , vol.49 , Issue.6 , pp. 505-507
    • H'Ng, M.W.1    Ho, Y.Y.2
  • 16
    • 0017114337 scopus 로고
    • Paget's disease of bone in South African Blacks
    • Pompe Van Meerdervoort H.F., Richter G.G. Paget's disease of bone in South African Blacks. S Afr Med J 1976, 50(47):1897-1899.
    • (1976) S Afr Med J , vol.50 , Issue.47 , pp. 1897-1899
    • Pompe Van Meerdervoort, H.F.1    Richter, G.G.2
  • 17
    • 0023154632 scopus 로고
    • Paget's disease of bone in Africans
    • Dahniya M.H. Paget's disease of bone in Africans. Br J Radiol 1987, 60(710):113-116.
    • (1987) Br J Radiol , vol.60 , Issue.710 , pp. 113-116
    • Dahniya, M.H.1
  • 18
    • 0028027753 scopus 로고
    • Demographic aspects of Paget's disease of bone in the Negev of southern Israel
    • Magen H., Liel Y., Bearman J.E., Lowenthal M.N. Demographic aspects of Paget's disease of bone in the Negev of southern Israel. Calcif Tissue Int 1994, 55(5):353-355.
    • (1994) Calcif Tissue Int , vol.55 , Issue.5 , pp. 353-355
    • Magen, H.1    Liel, Y.2    Bearman, J.E.3    Lowenthal, M.N.4
  • 19
    • 0022373384 scopus 로고
    • Prevalence of Paget's disease of bone in hospital patients in Jerusalem: an epidemiologic study
    • Bloom R.A., Libson E., Blank P., Nubani N. Prevalence of Paget's disease of bone in hospital patients in Jerusalem: an epidemiologic study. Isr J Med Sci 1985, 21(12):954-956.
    • (1985) Isr J Med Sci , vol.21 , Issue.12 , pp. 954-956
    • Bloom, R.A.1    Libson, E.2    Blank, P.3    Nubani, N.4
  • 21
    • 0030326102 scopus 로고    scopus 로고
    • The second case of Paget's disease (osteitis deformans) in a Chinese lady
    • Yip K.M., Lee Y.L., Kumta S.M., Lin J. The second case of Paget's disease (osteitis deformans) in a Chinese lady. Singapore Med J 1996, 37(6):665-667.
    • (1996) Singapore Med J , vol.37 , Issue.6 , pp. 665-667
    • Yip, K.M.1    Lee, Y.L.2    Kumta, S.M.3    Lin, J.4
  • 23
    • 0030950686 scopus 로고    scopus 로고
    • Paget bone disease involving young adults in 3 generations of a Korean family
    • Kim G.S., Kim S.H., Cho J.K., Park J.Y., Shin M.J., Shong Y.K., et al. Paget bone disease involving young adults in 3 generations of a Korean family. Medicine (Baltimore) 1997, 76(3):157-169.
    • (1997) Medicine (Baltimore) , vol.76 , Issue.3 , pp. 157-169
    • Kim, G.S.1    Kim, S.H.2    Cho, J.K.3    Park, J.Y.4    Shin, M.J.5    Shong, Y.K.6
  • 24
    • 0018275969 scopus 로고
    • Radiological prevalence of Paget's disease of bone in British migrants to Australia
    • Gardner M.J., Guyer P.B., Barker D.J. Radiological prevalence of Paget's disease of bone in British migrants to Australia. BMJ 1978, 1(6128):1655-1657.
    • (1978) BMJ , vol.1 , Issue.6128 , pp. 1655-1657
    • Gardner, M.J.1    Guyer, P.B.2    Barker, D.J.3
  • 25
    • 0036094026 scopus 로고    scopus 로고
    • Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone
    • Laurin N., Brown J.P., Morissette J., Raymond V. Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone. Am J Hum Genet 2002, 70(6):1582-1588.
    • (2002) Am J Hum Genet , vol.70 , Issue.6 , pp. 1582-1588
    • Laurin, N.1    Brown, J.P.2    Morissette, J.3    Raymond, V.4
  • 26
    • 34247861003 scopus 로고    scopus 로고
    • Sequestosome 1: mutation frequencies, haplotypes, and phenotypes in familial Paget's disease of bone
    • Morissette J., Laurin N., Brown J.P. Sequestosome 1: mutation frequencies, haplotypes, and phenotypes in familial Paget's disease of bone. J Bone Miner Res 2006, 21(Suppl 2):P38-P44.
    • (2006) J Bone Miner Res , vol.21 , Issue.SUPPL. 2
    • Morissette, J.1    Laurin, N.2    Brown, J.P.3
  • 27
    • 0036755909 scopus 로고    scopus 로고
    • Guidelines on the management of Paget's disease of bone
    • Selby P.L., Davie M.W., Ralston S.H., Stone M.D. Guidelines on the management of Paget's disease of bone. Bone 2002, 31(3):366-373.
    • (2002) Bone , vol.31 , Issue.3 , pp. 366-373
    • Selby, P.L.1    Davie, M.W.2    Ralston, S.H.3    Stone, M.D.4
  • 28
    • 4444339384 scopus 로고    scopus 로고
    • Paget's disease of bone
    • Mosby, Toronto, Canada, M.C. Hochberg, A.J. Silman, J.S. Smolen, M.E. Weinblatt, M.H. Weisman (Eds.)
    • Devogelaer J.P., Nagant de Deuxchaisnes C. Paget's disease of bone. Rheumatology 2003, vol. 2:2139-2147. Mosby, Toronto, Canada. 3rd ed. M.C. Hochberg, A.J. Silman, J.S. Smolen, M.E. Weinblatt, M.H. Weisman (Eds.).
    • (2003) Rheumatology , vol.2 , pp. 2139-2147
    • Devogelaer, J.P.1    Nagant de Deuxchaisnes, C.2
  • 29
    • 46749127771 scopus 로고    scopus 로고
    • Pathogenesis and management of Paget's disease of bone
    • Ralston S.H., Langston A.L., Reid I.R. Pathogenesis and management of Paget's disease of bone. Lancet 2008, 372(9633):155-163.
    • (2008) Lancet , vol.372 , Issue.9633 , pp. 155-163
    • Ralston, S.H.1    Langston, A.L.2    Reid, I.R.3
  • 30
    • 0033827136 scopus 로고    scopus 로고
    • Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D(3) and RANKL
    • Neale S.D., Smith R., Wass J.A., Athanasou N.A. Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D(3) and RANKL. Bone 2000, 27(3):409-416.
    • (2000) Bone , vol.27 , Issue.3 , pp. 409-416
    • Neale, S.D.1    Smith, R.2    Wass, J.A.3    Athanasou, N.A.4
  • 31
    • 0033963129 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 hypersensitivity of osteoclast precursors from patients with Paget's disease
    • Menaa C., Barsony J., Reddy S.V., Cornish J., Cundy T., Roodman G.D. 1,25-Dihydroxyvitamin D3 hypersensitivity of osteoclast precursors from patients with Paget's disease. J Bone Miner Res 2000, 15(2):228-236.
    • (2000) J Bone Miner Res , vol.15 , Issue.2 , pp. 228-236
    • Menaa, C.1    Barsony, J.2    Reddy, S.V.3    Cornish, J.4    Cundy, T.5    Roodman, G.D.6
  • 32
    • 0033932526 scopus 로고    scopus 로고
    • Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone
    • Menaa C., Reddy S.V., Kurihara N., Maeda H., Anderson D., Cundy T., et al. Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone. J Clin Invest 2000, 105(12):1833-1838.
    • (2000) J Clin Invest , vol.105 , Issue.12 , pp. 1833-1838
    • Menaa, C.1    Reddy, S.V.2    Kurihara, N.3    Maeda, H.4    Anderson, D.5    Cundy, T.6
  • 33
    • 15244347056 scopus 로고    scopus 로고
    • Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's disease
    • Kurihara N., Reddy S.V., Araki N., Ishizuka S., Ozono K., Cornish J., et al. Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's disease. J Bone Miner Res 2004, 19(7):1154-1164.
    • (2004) J Bone Miner Res , vol.19 , Issue.7 , pp. 1154-1164
    • Kurihara, N.1    Reddy, S.V.2    Araki, N.3    Ishizuka, S.4    Ozono, K.5    Cornish, J.6
  • 34
    • 0017087884 scopus 로고
    • Nuclear inclusions in osteoclasts in Paget's bone disease
    • Rebel A., Malkani K., Basle M., Bregeon C. Nuclear inclusions in osteoclasts in Paget's bone disease. Calcif Tissue Res 1976, 21(Suppl):113-116.
    • (1976) Calcif Tissue Res , vol.21 , Issue.SUPPL. , pp. 113-116
    • Rebel, A.1    Malkani, K.2    Basle, M.3    Bregeon, C.4
  • 35
    • 0017114175 scopus 로고
    • Nuclear inclusions in Paget's disease of bone
    • Mills B.G., Singer F.R. Nuclear inclusions in Paget's disease of bone. Science 1976, 194(4261):201-202.
    • (1976) Science , vol.194 , Issue.4261 , pp. 201-202
    • Mills, B.G.1    Singer, F.R.2
  • 36
    • 0019996989 scopus 로고
    • Ultrastructural features of the osteoclasts from Paget's disease of bone in relation to a viral aetiology
    • Harvey L., Gray T., Beneton M.N., Douglas D.L., Kanis J.A., Russell R.G. Ultrastructural features of the osteoclasts from Paget's disease of bone in relation to a viral aetiology. J Clin Pathol 1982, 35(7):771-779.
    • (1982) J Clin Pathol , vol.35 , Issue.7 , pp. 771-779
    • Harvey, L.1    Gray, T.2    Beneton, M.N.3    Douglas, D.L.4    Kanis, J.A.5    Russell, R.G.6
  • 37
    • 0019964902 scopus 로고
    • Microfilaments associated with Paget's disease of bone: comparison with nucleocapsids of measles virus and respiratory syncytial virus
    • Howatson A.F., Fornasier V.L. Microfilaments associated with Paget's disease of bone: comparison with nucleocapsids of measles virus and respiratory syncytial virus. Intervirology 1982, 18(3):150-159.
    • (1982) Intervirology , vol.18 , Issue.3 , pp. 150-159
    • Howatson, A.F.1    Fornasier, V.L.2
  • 38
    • 0018821245 scopus 로고
    • Fine structure of nuclei and cytoplasm of osteoclasts in Paget's disease of bone
    • Gherardi G., Lo Cascio V., Bonucci E. Fine structure of nuclei and cytoplasm of osteoclasts in Paget's disease of bone. Histopathology 1980, 4(1):63-74.
    • (1980) Histopathology , vol.4 , Issue.1 , pp. 63-74
    • Gherardi, G.1    Lo Cascio, V.2    Bonucci, E.3
  • 39
    • 78649476618 scopus 로고    scopus 로고
    • Paget disease of bone
    • Roodman G.D., Windle J.J. Paget disease of bone. J Clin Invest 2005, 115(2):200-208.
    • (2005) J Clin Invest , vol.115 , Issue.2 , pp. 200-208
    • Roodman, G.D.1    Windle, J.J.2
  • 40
    • 33846541850 scopus 로고    scopus 로고
    • Osteosarcoma in Paget's disease of bone
    • Hansen M.F., Seton M., Merchant A. Osteosarcoma in Paget's disease of bone. J Bone Miner Res 2006, 21(Suppl 2):58-63.
    • (2006) J Bone Miner Res , vol.21 , Issue.SUPPL. 2 , pp. 58-63
    • Hansen, M.F.1    Seton, M.2    Merchant, A.3
  • 42
    • 78650967704 scopus 로고    scopus 로고
    • Paget's disease of bone: the skeletal distribution, complications and quality of life as perceived by patients
    • Seton M., Moses A.M., Bode R.K., Schwartz C. Paget's disease of bone: the skeletal distribution, complications and quality of life as perceived by patients. Bone 2011, 48(2):281-285.
    • (2011) Bone , vol.48 , Issue.2 , pp. 281-285
    • Seton, M.1    Moses, A.M.2    Bode, R.K.3    Schwartz, C.4
  • 43
    • 30644469500 scopus 로고    scopus 로고
    • RANKL-RANK signaling in osteoclastogenesis and bone disease
    • Wada T., Nakashima T., Hiroshi N., Penninger J.M. RANKL-RANK signaling in osteoclastogenesis and bone disease. Trends Mol Med 2006, 12(1):17-25.
    • (2006) Trends Mol Med , vol.12 , Issue.1 , pp. 17-25
    • Wada, T.1    Nakashima, T.2    Hiroshi, N.3    Penninger, J.M.4
  • 44
    • 9244252016 scopus 로고    scopus 로고
    • The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling
    • Theoleyre S., Wittrant Y., Tat S.K., Fortun Y., Redini F., Heymann D. The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling. Cytokine Growth Factor Rev 2004, 15(6):457-475.
    • (2004) Cytokine Growth Factor Rev , vol.15 , Issue.6 , pp. 457-475
    • Theoleyre, S.1    Wittrant, Y.2    Tat, S.K.3    Fortun, Y.4    Redini, F.5    Heymann, D.6
  • 45
    • 34547521058 scopus 로고    scopus 로고
    • Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL
    • Sobacchi C., Frattini A., Guerrini M.M., Abinun M., Pangrazio A., Susani L., et al. Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL. Nat Genet 2007, 39(8):960-962.
    • (2007) Nat Genet , vol.39 , Issue.8 , pp. 960-962
    • Sobacchi, C.1    Frattini, A.2    Guerrini, M.M.3    Abinun, M.4    Pangrazio, A.5    Susani, L.6
  • 46
    • 46349084493 scopus 로고    scopus 로고
    • Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations
    • Guerrini M.M., Sobacchi C., Cassani B., Abinun M., Kilic S.S., Pangrazio A., et al. Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations. Am J Hum Genet 2008, 83(1):64-76.
    • (2008) Am J Hum Genet , vol.83 , Issue.1 , pp. 64-76
    • Guerrini, M.M.1    Sobacchi, C.2    Cassani, B.3    Abinun, M.4    Kilic, S.S.5    Pangrazio, A.6
  • 49
    • 0033987358 scopus 로고    scopus 로고
    • Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis
    • Hughes A.E., Ralston S.H., Marken J., Bell C., MacPherson H., Wallace R.G., et al. Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis. Nat Genet 2000, 24(1):45-48.
    • (2000) Nat Genet , vol.24 , Issue.1 , pp. 45-48
    • Hughes, A.E.1    Ralston, S.H.2    Marken, J.3    Bell, C.4    MacPherson, H.5    Wallace, R.G.6
  • 50
    • 78651479733 scopus 로고    scopus 로고
    • New knowledge on critical osteoclast formation and activation pathways from study of rare genetic diseases of osteoclasts: focus on the RANK/RANKL axis
    • Crockett J.C., Mellis D.J., Scott D.I., Helfrich M.H. New knowledge on critical osteoclast formation and activation pathways from study of rare genetic diseases of osteoclasts: focus on the RANK/RANKL axis. Osteoporos Int 2011, 22(1):1-20.
    • (2011) Osteoporos Int , vol.22 , Issue.1 , pp. 1-20
    • Crockett, J.C.1    Mellis, D.J.2    Scott, D.I.3    Helfrich, M.H.4
  • 51
    • 0036778369 scopus 로고    scopus 로고
    • Familial expansile osteolysis in a large Spanish kindred resulting from an insertion mutation in the TNFRSF11A gene
    • Palenzuela L., Vives-Bauza C., Fernandez-Cadenas I., Meseguer A., Font N., Sarret E., et al. Familial expansile osteolysis in a large Spanish kindred resulting from an insertion mutation in the TNFRSF11A gene. J Med Genet 2002, 39(10):E67.
    • (2002) J Med Genet , vol.39 , Issue.10
    • Palenzuela, L.1    Vives-Bauza, C.2    Fernandez-Cadenas, I.3    Meseguer, A.4    Font, N.5    Sarret, E.6
  • 52
    • 34247335806 scopus 로고    scopus 로고
    • Intragenic SNP haplotypes associated with 84dup18 mutation in TNFRSF11A in four FEO pedigrees suggest three independent origins for this mutation
    • Elahi E., Shafaghati Y., Asadi S., Absalan F., Goodarzi H., Gharaii N., et al. Intragenic SNP haplotypes associated with 84dup18 mutation in TNFRSF11A in four FEO pedigrees suggest three independent origins for this mutation. J Bone Miner Metab 2007, 25(3):159-164.
    • (2007) J Bone Miner Metab , vol.25 , Issue.3 , pp. 159-164
    • Elahi, E.1    Shafaghati, Y.2    Asadi, S.3    Absalan, F.4    Goodarzi, H.5    Gharaii, N.6
  • 53
    • 0037304062 scopus 로고    scopus 로고
    • Identification of a novel tandem duplication in exon 1 of the TNFRSF11A gene in two unrelated patients with familial expansile osteolysis
    • Johnson-Pais T.L., Singer F.R., Bone H.G., McMurray C.T., Hansen M.F., Leach R.J. Identification of a novel tandem duplication in exon 1 of the TNFRSF11A gene in two unrelated patients with familial expansile osteolysis. J Bone Miner Res 2003, 18(2):376-380.
    • (2003) J Bone Miner Res , vol.18 , Issue.2 , pp. 376-380
    • Johnson-Pais, T.L.1    Singer, F.R.2    Bone, H.G.3    McMurray, C.T.4    Hansen, M.F.5    Leach, R.J.6
  • 55
    • 33744765838 scopus 로고    scopus 로고
    • Paget's disease of bone and genetic disorders of RANKL/OPG/RANK/NF-kappaB signaling
    • Whyte M.P. Paget's disease of bone and genetic disorders of RANKL/OPG/RANK/NF-kappaB signaling. Ann NY Acad Sci 2006, 1068:143-164.
    • (2006) Ann NY Acad Sci , vol.1068 , pp. 143-164
    • Whyte, M.P.1
  • 56
    • 0036133351 scopus 로고    scopus 로고
    • Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis
    • Whyte M.P., Hughes A.E. Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis. J Bone Miner Res 2002, 17(1):26-29.
    • (2002) J Bone Miner Res , vol.17 , Issue.1 , pp. 26-29
    • Whyte, M.P.1    Hughes, A.E.2
  • 57
    • 0038643034 scopus 로고    scopus 로고
    • Phenotypic characterization of early onset Paget's disease of bone caused by a 27-bp duplication in the TNFRSF11A gene
    • Nakatsuka K., Nishizawa Y., Ralston S.H. Phenotypic characterization of early onset Paget's disease of bone caused by a 27-bp duplication in the TNFRSF11A gene. J Bone Miner Res 2003, 18(8):1381-1385.
    • (2003) J Bone Miner Res , vol.18 , Issue.8 , pp. 1381-1385
    • Nakatsuka, K.1    Nishizawa, Y.2    Ralston, S.H.3
  • 58
    • 68349118945 scopus 로고    scopus 로고
    • Early onset Paget's disease of bone caused by a novel mutation (78dup27) of the TNFRSF11A gene in a Chinese family
    • Ke Y.H., Yue H., He J.W., Liu Y.J., Zhang Z.L. Early onset Paget's disease of bone caused by a novel mutation (78dup27) of the TNFRSF11A gene in a Chinese family. Acta Pharmacol Sin 2009, 30(8):1204-1210.
    • (2009) Acta Pharmacol Sin , vol.30 , Issue.8 , pp. 1204-1210
    • Ke, Y.H.1    Yue, H.2    He, J.W.3    Liu, Y.J.4    Zhang, Z.L.5
  • 60
    • 18544371504 scopus 로고    scopus 로고
    • A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype
    • Cundy T., Hegde M., Naot D., Chong B., King A., Wallace R., et al. A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype. Hum Mol Genet 2002, 11(18):2119-2127.
    • (2002) Hum Mol Genet , vol.11 , Issue.18 , pp. 2119-2127
    • Cundy, T.1    Hegde, M.2    Naot, D.3    Chong, B.4    King, A.5    Wallace, R.6
  • 61
    • 34548253518 scopus 로고    scopus 로고
    • Juvenile Paget's disease: the second reported, oldest patient is homozygous for the TNFRSF11B "Balkan" mutation (966_969delTGACinsCTT), which elevates circulating immunoreactive osteoprotegerin levels
    • Whyte M.P., Singhellakis P.N., Petersen M.B., Davies M., Totty W.G., Mumm S. Juvenile Paget's disease: the second reported, oldest patient is homozygous for the TNFRSF11B "Balkan" mutation (966_969delTGACinsCTT), which elevates circulating immunoreactive osteoprotegerin levels. J Bone Miner Res 2007, 22(6):938-946.
    • (2007) J Bone Miner Res , vol.22 , Issue.6 , pp. 938-946
    • Whyte, M.P.1    Singhellakis, P.N.2    Petersen, M.B.3    Davies, M.4    Totty, W.G.5    Mumm, S.6
  • 62
    • 15544363030 scopus 로고    scopus 로고
    • An intermediate form of juvenile Paget's disease caused by a truncating TNFRSF11B mutation
    • Janssens K., de Vernejoul M.C., de Freitas F., Vanhoenacker F., Van Hul W. An intermediate form of juvenile Paget's disease caused by a truncating TNFRSF11B mutation. Bone 2005, 36(3):542-548.
    • (2005) Bone , vol.36 , Issue.3 , pp. 542-548
    • Janssens, K.1    de Vernejoul, M.C.2    de Freitas, F.3    Vanhoenacker, F.4    Van Hul, W.5
  • 63
    • 10744230044 scopus 로고    scopus 로고
    • Idiopathic hyperphosphatasia and TNFRSF11B mutations: relationships between phenotype and genotype
    • Chong B., Hegde M., Fawkner M., Simonet S., Cassinelli H., Coker M., et al. Idiopathic hyperphosphatasia and TNFRSF11B mutations: relationships between phenotype and genotype. J Bone Miner Res 2003, 18(12):2095-2104.
    • (2003) J Bone Miner Res , vol.18 , Issue.12 , pp. 2095-2104
    • Chong, B.1    Hegde, M.2    Fawkner, M.3    Simonet, S.4    Cassinelli, H.5    Coker, M.6
  • 64
    • 56449111307 scopus 로고    scopus 로고
    • VCP disease associated with myopathy. Paget disease of bone and frontotemporal dementia: review of a unique disorder
    • Kimonis V.E., Fulchiero E., Vesa J., Watts G. VCP disease associated with myopathy. Paget disease of bone and frontotemporal dementia: review of a unique disorder. Biochim Biophys Acta 2008, 1782(12):744-748.
    • (2008) Biochim Biophys Acta , vol.1782 , Issue.12 , pp. 744-748
    • Kimonis, V.E.1    Fulchiero, E.2    Vesa, J.3    Watts, G.4
  • 65
    • 18244381306 scopus 로고    scopus 로고
    • Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: hereditary inclusion body myopathy. Paget disease of bone, and frontotemporal dementia
    • Kovach M.J., Waggoner B., Leal S.M., Gelber D., Khardori R., Levenstien M.A., et al. Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: hereditary inclusion body myopathy. Paget disease of bone, and frontotemporal dementia. Mol Genet Metab 2001, 74(4):458-475.
    • (2001) Mol Genet Metab , vol.74 , Issue.4 , pp. 458-475
    • Kovach, M.J.1    Waggoner, B.2    Leal, S.M.3    Gelber, D.4    Khardori, R.5    Levenstien, M.A.6
  • 66
    • 1842483843 scopus 로고    scopus 로고
    • Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
    • Watts G.D., Wymer J., Kovach M.J., Mehta S.G., Mumm S., Darvish D., et al. Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat Genet 2004, 36(4):377-381.
    • (2004) Nat Genet , vol.36 , Issue.4 , pp. 377-381
    • Watts, G.D.1    Wymer, J.2    Kovach, M.J.3    Mehta, S.G.4    Mumm, S.5    Darvish, D.6
  • 67
    • 77952533111 scopus 로고    scopus 로고
    • VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
    • Tresse E., Salomons F.A., Vesa J., Bott L.C., Kimonis V., Yao T.P., et al. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD. Autophagy 2010, 6(2):217-227.
    • (2010) Autophagy , vol.6 , Issue.2 , pp. 217-227
    • Tresse, E.1    Salomons, F.A.2    Vesa, J.3    Bott, L.C.4    Kimonis, V.5    Yao, T.P.6
  • 68
    • 35348909072 scopus 로고    scopus 로고
    • Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia
    • Watts G.D., Thomasova D., Ramdeen S.K., Fulchiero E.C., Mehta S.G., Drachman D.A., et al. Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia. Clin Genet 2007, 72(5):420-426.
    • (2007) Clin Genet , vol.72 , Issue.5 , pp. 420-426
    • Watts, G.D.1    Thomasova, D.2    Ramdeen, S.K.3    Fulchiero, E.C.4    Mehta, S.G.5    Drachman, D.A.6
  • 69
    • 62849091775 scopus 로고    scopus 로고
    • A novel mutation in the VCP gene (G157R) in a German family with inclusion-body myopathy with Paget disease of bone and frontotemporal dementia
    • Djamshidian A., Schaefer J., Haubenberger D., Stogmann E., Zimprich F., Auff E., et al. A novel mutation in the VCP gene (G157R) in a German family with inclusion-body myopathy with Paget disease of bone and frontotemporal dementia. Muscle Nerve 2009, 39(3):389-391.
    • (2009) Muscle Nerve , vol.39 , Issue.3 , pp. 389-391
    • Djamshidian, A.1    Schaefer, J.2    Haubenberger, D.3    Stogmann, E.4    Zimprich, F.5    Auff, E.6
  • 70
  • 71
    • 27144483812 scopus 로고    scopus 로고
    • Inclusion body myopathy and Paget disease is linked to a novel mutation in the VCP gene
    • Haubenberger D., Bittner R.E., Rauch-Shorny S., Zimprich F., Mannhalter C., Wagner L., et al. Inclusion body myopathy and Paget disease is linked to a novel mutation in the VCP gene. Neurology 2005, 65(8):1304-1305.
    • (2005) Neurology , vol.65 , Issue.8 , pp. 1304-1305
    • Haubenberger, D.1    Bittner, R.E.2    Rauch-Shorny, S.3    Zimprich, F.4    Mannhalter, C.5    Wagner, L.6
  • 72
    • 0026785998 scopus 로고
    • Canine distemper virus transcripts sequenced from pagetic bone
    • Gordon M.T., Mee A.P., Anderson D.C., Sharpe P.T. Canine distemper virus transcripts sequenced from pagetic bone. Bone Miner 1992, 19(2):159-174.
    • (1992) Bone Miner , vol.19 , Issue.2 , pp. 159-174
    • Gordon, M.T.1    Mee, A.P.2    Anderson, D.C.3    Sharpe, P.T.4
  • 73
    • 0025742622 scopus 로고
    • Canine distemper virus localised in bone cells of patients with Paget's disease
    • Gordon M.T., Anderson D.C., Sharpe P.T. Canine distemper virus localised in bone cells of patients with Paget's disease. Bone 1991, 12(3):195-201.
    • (1991) Bone , vol.12 , Issue.3 , pp. 195-201
    • Gordon, M.T.1    Anderson, D.C.2    Sharpe, P.T.3
  • 74
    • 0032146198 scopus 로고    scopus 로고
    • Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase-polymerase chain reaction
    • Mee A.P., Dixon J.A., Hoyland J.A., Davies M., Selby P.L., Mawer E.B. Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase-polymerase chain reaction. Bone 1998, 23(2):171-175.
    • (1998) Bone , vol.23 , Issue.2 , pp. 171-175
    • Mee, A.P.1    Dixon, J.A.2    Hoyland, J.A.3    Davies, M.4    Selby, P.L.5    Mawer, E.B.6
  • 75
    • 33846433786 scopus 로고    scopus 로고
    • Canine distemper virus induces human osteoclastogenesis through NF-kappaB and sequestosome 1/P62 activation
    • Selby P.L., Davies M., Mee A.P. Canine distemper virus induces human osteoclastogenesis through NF-kappaB and sequestosome 1/P62 activation. J Bone Miner Res 2006, 21(11):1750-1756.
    • (2006) J Bone Miner Res , vol.21 , Issue.11 , pp. 1750-1756
    • Selby, P.L.1    Davies, M.2    Mee, A.P.3
  • 76
    • 0021337486 scopus 로고
    • Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone
    • Mills B.G., Singer F.R., Weiner L.P., Suffin S.C., Stabile E., Holst P. Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone. Clin Orthop Relat Res 1984, (183):303-311.
    • (1984) Clin Orthop Relat Res , Issue.183 , pp. 303-311
    • Mills, B.G.1    Singer, F.R.2    Weiner, L.P.3    Suffin, S.C.4    Stabile, E.5    Holst, P.6
  • 77
    • 0022548561 scopus 로고
    • Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization
    • Basle M.F., Fournier J.G., Rozenblatt S., Rebel A., Bouteille M. Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization. J Gen Virol 1986, 67(Pt 5):907-913.
    • (1986) J Gen Virol , vol.67 , Issue.PART 5 , pp. 907-913
    • Basle, M.F.1    Fournier, J.G.2    Rozenblatt, S.3    Rebel, A.4    Bouteille, M.5
  • 78
    • 0029003364 scopus 로고
    • Bone marrow mononuclear cells from patients with Paget's disease contain measles virus nucleocapsid messenger ribonucleic acid that has mutations in a specific region of the sequence
    • Reddy S.V., Singer F.R., Roodman G.D. Bone marrow mononuclear cells from patients with Paget's disease contain measles virus nucleocapsid messenger ribonucleic acid that has mutations in a specific region of the sequence. J Clin Endocrinol Metab 1995, 80(7):2108-2111.
    • (1995) J Clin Endocrinol Metab , vol.80 , Issue.7 , pp. 2108-2111
    • Reddy, S.V.1    Singer, F.R.2    Roodman, G.D.3
  • 79
    • 0036133370 scopus 로고    scopus 로고
    • Sequence analysis of measles virus nucleocapsid transcripts in patients with Paget's disease
    • Friedrichs W.E., Reddy S.V., Bruder J.M., Cundy T., Cornish J., Singer F.R., et al. Sequence analysis of measles virus nucleocapsid transcripts in patients with Paget's disease. J Bone Miner Res 2002, 17(1):145-151.
    • (2002) J Bone Miner Res , vol.17 , Issue.1 , pp. 145-151
    • Friedrichs, W.E.1    Reddy, S.V.2    Bruder, J.M.3    Cundy, T.4    Cornish, J.5    Singer, F.R.6
  • 80
    • 0029911056 scopus 로고    scopus 로고
    • Detection of measles virus nucleocapsid transcripts in circulating blood cells from patients with Paget disease
    • Reddy S.V., Singer F.R., Mallette L., Roodman G.D. Detection of measles virus nucleocapsid transcripts in circulating blood cells from patients with Paget disease. J Bone Miner Res 1996, 11(11):1602-1607.
    • (1996) J Bone Miner Res , vol.11 , Issue.11 , pp. 1602-1607
    • Reddy, S.V.1    Singer, F.R.2    Mallette, L.3    Roodman, G.D.4
  • 81
    • 0019508461 scopus 로고
    • Immunohistological demonstration of respiratory syncytial virus antigens in Paget disease of bone
    • Mills B.G., Singer F.R., Weiner L.P., Holst P.A. Immunohistological demonstration of respiratory syncytial virus antigens in Paget disease of bone. Proc Natl Acad Sci USA 1981, 78(2):1209-1213.
    • (1981) Proc Natl Acad Sci USA , vol.78 , Issue.2 , pp. 1209-1213
    • Mills, B.G.1    Singer, F.R.2    Weiner, L.P.3    Holst, P.A.4
  • 82
    • 0022256595 scopus 로고
    • Paramyxovirus antigens in osteoclasts from Paget's bone tissue detected by monoclonal antibodies
    • Basle M.F., Russell W.C., Goswami K.K., Rebel A., Giraudon P., Wild F., et al. Paramyxovirus antigens in osteoclasts from Paget's bone tissue detected by monoclonal antibodies. J Gen Virol 1985, 66(Pt 10):2103-2110.
    • (1985) J Gen Virol , vol.66 , Issue.PART 10 , pp. 2103-2110
    • Basle, M.F.1    Russell, W.C.2    Goswami, K.K.3    Rebel, A.4    Giraudon, P.5    Wild, F.6
  • 83
    • 0025720792 scopus 로고
    • Failure to detect paramyxovirus sequences in Paget's disease of bone using the polymerase chain reaction
    • Ralston S.H., Digiovine F.S., Gallacher S.J., Boyle I.T., Duff G.W. Failure to detect paramyxovirus sequences in Paget's disease of bone using the polymerase chain reaction. J Bone Miner Res 1991, 6(11):1243-1248.
    • (1991) J Bone Miner Res , vol.6 , Issue.11 , pp. 1243-1248
    • Ralston, S.H.1    Digiovine, F.S.2    Gallacher, S.J.3    Boyle, I.T.4    Duff, G.W.5
  • 84
    • 0026956388 scopus 로고
    • In situ analysis of Paget's disease of bone for measles-specific PCR-amplified cDNA
    • Nuovo M.A., Nuovo G.J., MacConnell P., Forde A., Steiner G.C. In situ analysis of Paget's disease of bone for measles-specific PCR-amplified cDNA. Diagn Mol Pathol 1992, 1(4):256-265.
    • (1992) Diagn Mol Pathol , vol.1 , Issue.4 , pp. 256-265
    • Nuovo, M.A.1    Nuovo, G.J.2    MacConnell, P.3    Forde, A.4    Steiner, G.C.5
  • 86
    • 0033713488 scopus 로고    scopus 로고
    • A negative search for a paramyxoviral etiology of Paget's disease of bone: molecular, immunological, and ultrastructural studies in UK patients
    • Helfrich M.H., Hobson R.P., Grabowski P.S., Zurbriggen A., Cosby S.L., Dickson G.R., et al. A negative search for a paramyxoviral etiology of Paget's disease of bone: molecular, immunological, and ultrastructural studies in UK patients. J Bone Miner Res 2000, 15(12):2315-2329.
    • (2000) J Bone Miner Res , vol.15 , Issue.12 , pp. 2315-2329
    • Helfrich, M.H.1    Hobson, R.P.2    Grabowski, P.S.3    Zurbriggen, A.4    Cosby, S.L.5    Dickson, G.R.6
  • 87
    • 0033831096 scopus 로고    scopus 로고
    • Absence of measles virus and canine distemper virus transcripts in long-term bone marrow cultures from patients with Paget's disease of bone
    • Ooi C.G., Walsh C.A., Gallagher J.A., Fraser W.D. Absence of measles virus and canine distemper virus transcripts in long-term bone marrow cultures from patients with Paget's disease of bone. Bone 2000, 27(3):417-421.
    • (2000) Bone , vol.27 , Issue.3 , pp. 417-421
    • Ooi, C.G.1    Walsh, C.A.2    Gallagher, J.A.3    Fraser, W.D.4
  • 89
    • 42049109083 scopus 로고    scopus 로고
    • Failure to detect measles virus ribonucleic acid in bone cells from patients with Paget's disease
    • Matthews B.G., Afzal M.A., Minor P.D., Bava U., Callon K.E., Pitto R.P., et al. Failure to detect measles virus ribonucleic acid in bone cells from patients with Paget's disease. J Clin Endocrinol Metab 2008, 93(4):1398-1401.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.4 , pp. 1398-1401
    • Matthews, B.G.1    Afzal, M.A.2    Minor, P.D.3    Bava, U.4    Callon, K.E.5    Pitto, R.P.6
  • 90
    • 0029116734 scopus 로고
    • Generation of multinucleated osteoclast-like cells from canine bone marrow: effects of canine distemper virus
    • Mee A.P., May C., Bennett D., Sharpe P.T. Generation of multinucleated osteoclast-like cells from canine bone marrow: effects of canine distemper virus. Bone 1995, 17(1):47-55.
    • (1995) Bone , vol.17 , Issue.1 , pp. 47-55
    • Mee, A.P.1    May, C.2    Bennett, D.3    Sharpe, P.T.4
  • 91
    • 0028853832 scopus 로고
    • Canine bone marrow cell cultures infected with canine distemper virus: an in vitro model of Paget's disease
    • Mee A.P., Hoyland J.A., Baird P., Bennett D., Sharpe P.T. Canine bone marrow cell cultures infected with canine distemper virus: an in vitro model of Paget's disease. Bone 1995, 17(Suppl 4):461S-466S.
    • (1995) Bone , vol.17 , Issue.SUPPL. 4
    • Mee, A.P.1    Hoyland, J.A.2    Baird, P.3    Bennett, D.4    Sharpe, P.T.5
  • 92
    • 0034104393 scopus 로고    scopus 로고
    • Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype
    • Kurihara N., Reddy S.V., Menaa C., Anderson D., Roodman G.D. Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype. J Clin Invest 2000, 105(5):607-614.
    • (2000) J Clin Invest , vol.105 , Issue.5 , pp. 607-614
    • Kurihara, N.1    Reddy, S.V.2    Menaa, C.3    Anderson, D.4    Roodman, G.D.5
  • 93
    • 0034989963 scopus 로고    scopus 로고
    • Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts
    • Reddy S.V., Kurihara N., Menaa C., Landucci G., Forthal D., Koop B.A., et al. Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts. Endocrinology 2001, 142(7):2898-2905.
    • (2001) Endocrinology , vol.142 , Issue.7 , pp. 2898-2905
    • Reddy, S.V.1    Kurihara, N.2    Menaa, C.3    Landucci, G.4    Forthal, D.5    Koop, B.A.6
  • 94
    • 33644529415 scopus 로고    scopus 로고
    • Expression of measles virus nucleocapsid protein in osteoclasts induces Paget's disease-like bone lesions in mice
    • Kurihara N., Zhou H., Reddy S.V., Garcia Palacios V., Subler M.A., Dempster D.W., et al. Expression of measles virus nucleocapsid protein in osteoclasts induces Paget's disease-like bone lesions in mice. J Bone Miner Res 2006, 21(3):446-455.
    • (2006) J Bone Miner Res , vol.21 , Issue.3 , pp. 446-455
    • Kurihara, N.1    Zhou, H.2    Reddy, S.V.3    Garcia Palacios, V.4    Subler, M.A.5    Dempster, D.W.6
  • 97
    • 0028221605 scopus 로고
    • Epidemiological aspects of Paget's disease: family history and relationship to other medical conditions
    • Siris E.S. Epidemiological aspects of Paget's disease: family history and relationship to other medical conditions. Semin Arthritis Rheum 1994, 23(4):222-225.
    • (1994) Semin Arthritis Rheum , vol.23 , Issue.4 , pp. 222-225
    • Siris, E.S.1
  • 98
    • 78349275672 scopus 로고    scopus 로고
    • Mutations of SQSTM1 are associated with severity and clinical outcome in paget disease of bone
    • Visconti M.R., Langston A.L., Alonso N., Goodman K., Selby P.L., Fraser W.D., et al. Mutations of SQSTM1 are associated with severity and clinical outcome in paget disease of bone. J Bone Miner Res 2010, 25(11):2368-2373.
    • (2010) J Bone Miner Res , vol.25 , Issue.11 , pp. 2368-2373
    • Visconti, M.R.1    Langston, A.L.2    Alonso, N.3    Goodman, K.4    Selby, P.L.5    Fraser, W.D.6
  • 99
    • 0036755763 scopus 로고    scopus 로고
    • Paget's disease of bone in Lancashire and arsenic pesticide in cotton mill wastewater: a speculative hypothesis
    • Lever J.H. Paget's disease of bone in Lancashire and arsenic pesticide in cotton mill wastewater: a speculative hypothesis. Bone 2002, 31(3):434-436.
    • (2002) Bone , vol.31 , Issue.3 , pp. 434-436
    • Lever, J.H.1
  • 100
    • 0038367669 scopus 로고    scopus 로고
    • Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts
    • Aono J., Yanagawa T., Itoh K., Li B., Yoshida H., Kumagai Y., et al. Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochem Biophys Res Commun 2003, 305(2):271-277.
    • (2003) Biochem Biophys Res Commun , vol.305 , Issue.2 , pp. 271-277
    • Aono, J.1    Yanagawa, T.2    Itoh, K.3    Li, B.4    Yoshida, H.5    Kumagai, Y.6
  • 101
    • 0035999447 scopus 로고    scopus 로고
    • Paget's disease in an archeological population
    • Rogers J., Jeffrey D.R., Watt I. Paget's disease in an archeological population. J Bone Miner Res 2002, 17(6):1127-1134.
    • (2002) J Bone Miner Res , vol.17 , Issue.6 , pp. 1127-1134
    • Rogers, J.1    Jeffrey, D.R.2    Watt, I.3
  • 103
    • 0019965276 scopus 로고
    • European distribution of Paget's disease of bone
    • Detheridge F.M., Guyer P.B., Barker D.J. European distribution of Paget's disease of bone. Br Med J (Clin Res Ed) 1982, 285(6347):1005-1008.
    • (1982) Br Med J (Clin Res Ed) , vol.285 , Issue.6347 , pp. 1005-1008
    • Detheridge, F.M.1    Guyer, P.B.2    Barker, D.J.3
  • 104
    • 0033941831 scopus 로고    scopus 로고
    • Prevalence of Paget's disease of bone and spinal hemangioma in French women older than 75 years: data from the EPIDOS study
    • Lecuyer N., Grados F., Dargent-Molina P., Deramond H., Meunier P.J., Fardellone P. Prevalence of Paget's disease of bone and spinal hemangioma in French women older than 75 years: data from the EPIDOS study. Joint Bone Spine 2000, 67(4):315-318.
    • (2000) Joint Bone Spine , vol.67 , Issue.4 , pp. 315-318
    • Lecuyer, N.1    Grados, F.2    Dargent-Molina, P.3    Deramond, H.4    Meunier, P.J.5    Fardellone, P.6
  • 105
    • 6344280692 scopus 로고    scopus 로고
    • Paget's disease of bone in The Netherlands: a population-based radiological and biochemical survey-the Rotterdam Study
    • Eekhoff M.E., van der Klift M., Kroon H.M., Cooper C., Hofman A., Pols H.A., et al. Paget's disease of bone in The Netherlands: a population-based radiological and biochemical survey-the Rotterdam Study. J Bone Miner Res 2004, 19(4):566-570.
    • (2004) J Bone Miner Res , vol.19 , Issue.4 , pp. 566-570
    • Eekhoff, M.E.1    van der Klift, M.2    Kroon, H.M.3    Cooper, C.4    Hofman, A.5    Pols, H.A.6
  • 106
    • 0021999930 scopus 로고
    • Paget's disease of bone in West Germany. Prevalence and distribution
    • Ziegler R., Holz G., Rotzler B., Minne H. Paget's disease of bone in West Germany. Prevalence and distribution. Clin Orthop Relat Res 1985, 194:199-204.
    • (1985) Clin Orthop Relat Res , vol.194 , pp. 199-204
    • Ziegler, R.1    Holz, G.2    Rotzler, B.3    Minne, H.4
  • 108
    • 0018787548 scopus 로고    scopus 로고
    • Paget's disease in Norway
    • (8150):
    • Falch JA. Paget's disease in Norway. Lancet 1022;2(8150):1022.
    • Lancet , vol.1022 , Issue.2 , pp. 1022
    • Falch, J.A.1
  • 112
    • 0037108914 scopus 로고    scopus 로고
    • Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease
    • Hocking L.J., Lucas G.J., Daroszewska A., Mangion J., Olavesen M., Cundy T., et al. Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease. Hum Mol Genet 2002, 11(22):2735-2739.
    • (2002) Hum Mol Genet , vol.11 , Issue.22 , pp. 2735-2739
    • Hocking, L.J.1    Lucas, G.J.2    Daroszewska, A.3    Mangion, J.4    Olavesen, M.5    Cundy, T.6
  • 114
    • 0034763552 scopus 로고    scopus 로고
    • Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35
    • Hocking L.J., Herbert C.A., Nicholls R.K., Williams F., Bennett S.T., Cundy T., et al. Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35. Am J Hum Genet 2001, 69(5):1055-1061.
    • (2001) Am J Hum Genet , vol.69 , Issue.5 , pp. 1055-1061
    • Hocking, L.J.1    Herbert, C.A.2    Nicholls, R.K.3    Williams, F.4    Bennett, S.T.5    Cundy, T.6
  • 116
    • 0017567886 scopus 로고
    • Evidence for linkage between HLA and Paget's disease
    • Fotino M., Haymovits A., Falk C.T. Evidence for linkage between HLA and Paget's disease. Transplant Proc 1977, 9(4):1867-1868.
    • (1977) Transplant Proc , vol.9 , Issue.4 , pp. 1867-1868
    • Fotino, M.1    Haymovits, A.2    Falk, C.T.3
  • 118
    • 2942709744 scopus 로고    scopus 로고
    • Identification of SQSTM1 mutations in familial Paget's disease in Australian pedigrees
    • Good D.A., Busfield F., Fletcher B.H., Lovelock P.K., Duffy D.L., Kesting J.B., et al. Identification of SQSTM1 mutations in familial Paget's disease in Australian pedigrees. Bone 2004, 35(1):277-282.
    • (2004) Bone , vol.35 , Issue.1 , pp. 277-282
    • Good, D.A.1    Busfield, F.2    Fletcher, B.H.3    Lovelock, P.K.4    Duffy, D.L.5    Kesting, J.B.6
  • 119
    • 0031778038 scopus 로고    scopus 로고
    • Paget's disease of bone: evidence for a susceptibility locus on chromosome 18q and for genetic heterogeneity
    • Haslam S.I., Van Hul W., Morales-Piga A., Balemans W., San-Millan J.L., Nakatsuka K., et al. Paget's disease of bone: evidence for a susceptibility locus on chromosome 18q and for genetic heterogeneity. J Bone Miner Res 1998, 13(6):911-917.
    • (1998) J Bone Miner Res , vol.13 , Issue.6 , pp. 911-917
    • Haslam, S.I.1    Van Hul, W.2    Morales-Piga, A.3    Balemans, W.4    San-Millan, J.L.5    Nakatsuka, K.6
  • 120
    • 0034065196 scopus 로고    scopus 로고
    • Familial Paget's disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q
    • Hocking L., Slee F., Haslam S.I., Cundy T., Nicholson G., van Hul W., et al. Familial Paget's disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q. Bone 2000, 26(6):577-580.
    • (2000) Bone , vol.26 , Issue.6 , pp. 577-580
    • Hocking, L.1    Slee, F.2    Haslam, S.I.3    Cundy, T.4    Nicholson, G.5    van Hul, W.6
  • 122
    • 37549034220 scopus 로고    scopus 로고
    • Identification of a major locus for Paget's disease on chromosome 10p13 in families of British descent
    • Lucas G.J., Riches P.L., Hocking L.J., Cundy T., Nicholson G.C., Walsh J.P., et al. Identification of a major locus for Paget's disease on chromosome 10p13 in families of British descent. J Bone Miner Res 2008, 23(1):58-63.
    • (2008) J Bone Miner Res , vol.23 , Issue.1 , pp. 58-63
    • Lucas, G.J.1    Riches, P.L.2    Hocking, L.J.3    Cundy, T.4    Nicholson, G.C.5    Walsh, J.P.6
  • 123
    • 19944434345 scopus 로고    scopus 로고
    • Ubiquitin-associated domain mutations of SQSTM1 in Paget's disease of bone: evidence for a founder effect in patients of British descent
    • Lucas G.J., Hocking L.J., Daroszewska A., Cundy T., Nicholson G.C., Walsh J.P., et al. Ubiquitin-associated domain mutations of SQSTM1 in Paget's disease of bone: evidence for a founder effect in patients of British descent. J Bone Miner Res 2005, 20(2):227-231.
    • (2005) J Bone Miner Res , vol.20 , Issue.2 , pp. 227-231
    • Lucas, G.J.1    Hocking, L.J.2    Daroszewska, A.3    Cundy, T.4    Nicholson, G.C.5    Walsh, J.P.6
  • 124
    • 58149280230 scopus 로고    scopus 로고
    • Genetic epidemiology of Paget's disease of bone in Italy: sequestosome1/p62 gene mutational test and haplotype analysis at 5q35 in a large representative series of sporadic and familial Italian cases of Paget's disease of bone
    • Falchetti A., Di Stefano M., Marini F., Ortolani S., Ulivieri M.F., Bergui S., et al. Genetic epidemiology of Paget's disease of bone in Italy: sequestosome1/p62 gene mutational test and haplotype analysis at 5q35 in a large representative series of sporadic and familial Italian cases of Paget's disease of bone. Calcif Tissue Int 2009, 84(1):20-37.
    • (2009) Calcif Tissue Int , vol.84 , Issue.1 , pp. 20-37
    • Falchetti, A.1    Di Stefano, M.2    Marini, F.3    Ortolani, S.4    Ulivieri, M.F.5    Bergui, S.6
  • 125
    • 50949105285 scopus 로고    scopus 로고
    • Founder effect in different European countries for the recurrent P392L SQSTM1 mutation in Paget's disease of bone
    • Chung P.Y., Beyens G., Guanabens N., Boonen S., Papapoulos S., Karperien M., et al. Founder effect in different European countries for the recurrent P392L SQSTM1 mutation in Paget's disease of bone. Calcif Tissue Int 2008, 83(1):34-42.
    • (2008) Calcif Tissue Int , vol.83 , Issue.1 , pp. 34-42
    • Chung, P.Y.1    Beyens, G.2    Guanabens, N.3    Boonen, S.4    Papapoulos, S.5    Karperien, M.6
  • 126
    • 33745510646 scopus 로고    scopus 로고
    • A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype
    • Rea S.L., Walsh J.P., Ward L., Yip K., Ward B.K., Kent G.N., et al. A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype. J Bone Miner Res 2006, 21(7):1136-1145.
    • (2006) J Bone Miner Res , vol.21 , Issue.7 , pp. 1136-1145
    • Rea, S.L.1    Walsh, J.P.2    Ward, L.3    Yip, K.4    Ward, B.K.5    Kent, G.N.6
  • 128
    • 33845435884 scopus 로고    scopus 로고
    • Identification and molecular characterization of a novel splice-site mutation (G1205C) in the SQSTM1 gene causing Paget's disease of bone in an extended American family
    • Beyens G., Wuyts W., Cleiren E., de Freitas F., Tiegs R., Van Hul W. Identification and molecular characterization of a novel splice-site mutation (G1205C) in the SQSTM1 gene causing Paget's disease of bone in an extended American family. Calcif Tissue Int 2006, 79(5):281-288.
    • (2006) Calcif Tissue Int , vol.79 , Issue.5 , pp. 281-288
    • Beyens, G.1    Wuyts, W.2    Cleiren, E.3    de Freitas, F.4    Tiegs, R.5    Van Hul, W.6
  • 129
    • 8644267864 scopus 로고    scopus 로고
    • Two novel mutations at exon 8 of the Sequestosome 1 (SQSTM1) gene in an Italian series of patients affected by Paget's disease of bone (PDB)
    • Falchetti A., Di Stefano M., Marini F., Del Monte F., Mavilia C., Strigoli D., et al. Two novel mutations at exon 8 of the Sequestosome 1 (SQSTM1) gene in an Italian series of patients affected by Paget's disease of bone (PDB). J Bone Miner Res 2004, 19(6):1013-1017.
    • (2004) J Bone Miner Res , vol.19 , Issue.6 , pp. 1013-1017
    • Falchetti, A.1    Di Stefano, M.2    Marini, F.3    Del Monte, F.4    Mavilia, C.5    Strigoli, D.6
  • 130
    • 57249109893 scopus 로고    scopus 로고
    • Vitamin D receptor gene polymorphisms predict acquired resistance to clodronate treatment in patients with Paget's disease of bone
    • Mossetti G., Gennari L., Rendina D., De Filippo G., Merlotti D., De Paola V., et al. Vitamin D receptor gene polymorphisms predict acquired resistance to clodronate treatment in patients with Paget's disease of bone. Calcif Tissue Int 2008, 83(6):414-424.
    • (2008) Calcif Tissue Int , vol.83 , Issue.6 , pp. 414-424
    • Mossetti, G.1    Gennari, L.2    Rendina, D.3    De Filippo, G.4    Merlotti, D.5    De Paola, V.6
  • 131
    • 77950664208 scopus 로고    scopus 로고
    • Insights into the pathogenesis of Paget's disease
    • Roodman G.D. Insights into the pathogenesis of Paget's disease. Ann NY Acad Sci 2010, 1192:176-180.
    • (2010) Ann NY Acad Sci , vol.1192 , pp. 176-180
    • Roodman, G.D.1
  • 132
    • 11944268320 scopus 로고    scopus 로고
    • SQSTM1 and Paget's disease of bone
    • Layfield R., Hocking L.J. SQSTM1 and Paget's disease of bone. Calcif Tissue Int 2004, 75(5):347-357.
    • (2004) Calcif Tissue Int , vol.75 , Issue.5 , pp. 347-357
    • Layfield, R.1    Hocking, L.J.2
  • 133
    • 0037070216 scopus 로고    scopus 로고
    • Structure and functional properties of the ubiquitin binding protein p62
    • Geetha T., Wooten M.W. Structure and functional properties of the ubiquitin binding protein p62. FEBS Lett 2002, 512(1-3):19-24.
    • (2002) FEBS Lett , vol.512 , Issue.1-3 , pp. 19-24
    • Geetha, T.1    Wooten, M.W.2
  • 134
    • 0020804563 scopus 로고
    • Ubiquitin: roles in protein modification and breakdown
    • Hershko A. Ubiquitin: roles in protein modification and breakdown. Cell 1983, 34(1):11-12.
    • (1983) Cell , vol.34 , Issue.1 , pp. 11-12
    • Hershko, A.1
  • 135
    • 9744227183 scopus 로고    scopus 로고
    • Ubiquitin: structures, functions, mechanisms
    • Pickart C.M., Eddins M.J. Ubiquitin: structures, functions, mechanisms. Biochim Biophys Acta 2004, 1695(1-3):55-72.
    • (2004) Biochim Biophys Acta , vol.1695 , Issue.1-3 , pp. 55-72
    • Pickart, C.M.1    Eddins, M.J.2
  • 136
    • 15344339092 scopus 로고    scopus 로고
    • Loss of ubiquitin-binding associated with Paget's disease of bone p62 (SQSTM1) mutations
    • Cavey J.R., Ralston S.H., Hocking L.J., Sheppard P.W., Ciani B., Searle M.S., et al. Loss of ubiquitin-binding associated with Paget's disease of bone p62 (SQSTM1) mutations. J Bone Miner Res 2005, 20(4):619-624.
    • (2005) J Bone Miner Res , vol.20 , Issue.4 , pp. 619-624
    • Cavey, J.R.1    Ralston, S.H.2    Hocking, L.J.3    Sheppard, P.W.4    Ciani, B.5    Searle, M.S.6
  • 137
    • 44649101850 scopus 로고    scopus 로고
    • Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series
    • Ikeda F., Dikic I. Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series. EMBO Rep 2008, 9(6):536-542.
    • (2008) EMBO Rep , vol.9 , Issue.6 , pp. 536-542
    • Ikeda, F.1    Dikic, I.2
  • 138
    • 0034602845 scopus 로고    scopus 로고
    • Recognition of the polyubiquitin proteolytic signal
    • Thrower J.S., Hoffman L., Rechsteiner M., Pickart C.M. Recognition of the polyubiquitin proteolytic signal. EMBO J 2000, 19(1):94-102.
    • (2000) EMBO J , vol.19 , Issue.1 , pp. 94-102
    • Thrower, J.S.1    Hoffman, L.2    Rechsteiner, M.3    Pickart, C.M.4
  • 139
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Chen Z.J. Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol 2005, 7(8):758-765.
    • (2005) Nat Cell Biol , vol.7 , Issue.8 , pp. 758-765
    • Chen, Z.J.1
  • 140
    • 0034599476 scopus 로고    scopus 로고
    • The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway
    • Sanz L., Diaz-Meco M.T., Nakano H., Moscat J. The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway. EMBO J 2000, 19(7):1576-1586.
    • (2000) EMBO J , vol.19 , Issue.7 , pp. 1576-1586
    • Sanz, L.1    Diaz-Meco, M.T.2    Nakano, H.3    Moscat, J.4
  • 141
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden M.S., Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008, 132(3):344-362.
    • (2008) Cell , vol.132 , Issue.3 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 142
    • 0034644474 scopus 로고    scopus 로고
    • Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
    • Deng L., Wang C., Spencer E., Yang L., Braun A., You J., et al. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 2000, 103(2):351-361.
    • (2000) Cell , vol.103 , Issue.2 , pp. 351-361
    • Deng, L.1    Wang, C.2    Spencer, E.3    Yang, L.4    Braun, A.5    You, J.6
  • 143
    • 27444433045 scopus 로고    scopus 로고
    • The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination
    • Wooten M.W., Geetha T., Seibenhener M.L., Babu J.R., Diaz-Meco M.T., Moscat J. The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination. J Biol Chem 2005, 280(42):35625-35629.
    • (2005) J Biol Chem , vol.280 , Issue.42 , pp. 35625-35629
    • Wooten, M.W.1    Geetha, T.2    Seibenhener, M.L.3    Babu, J.R.4    Diaz-Meco, M.T.5    Moscat, J.6
  • 144
    • 0036150184 scopus 로고    scopus 로고
    • Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK. TAB2, and TRAF6
    • Mizukami J., Takaesu G., Akatsuka H., Sakurai H., Ninomiya-Tsuji J., Matsumoto K., et al. Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK. TAB2, and TRAF6. Mol Cell Biol 2002, 22(4):992-1000.
    • (2002) Mol Cell Biol , vol.22 , Issue.4 , pp. 992-1000
    • Mizukami, J.1    Takaesu, G.2    Akatsuka, H.3    Sakurai, H.4    Ninomiya-Tsuji, J.5    Matsumoto, K.6
  • 146
    • 33947521944 scopus 로고    scopus 로고
    • TAK1-dependent signaling requires functional interaction with TAB2/TAB3
    • Besse A., Lamothe B., Campos A.D., Webster W.K., Maddineni U., Lin S.C., et al. TAK1-dependent signaling requires functional interaction with TAB2/TAB3. J Biol Chem 2007, 282(6):3918-3928.
    • (2007) J Biol Chem , vol.282 , Issue.6 , pp. 3918-3928
    • Besse, A.1    Lamothe, B.2    Campos, A.D.3    Webster, W.K.4    Maddineni, U.5    Lin, S.C.6
  • 147
    • 33645703930 scopus 로고    scopus 로고
    • Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
    • Wu C.J., Conze D.B., Li T., Srinivasula S.M., Ashwell J.D. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol 2006, 8(4):398-406.
    • (2006) Nat Cell Biol , vol.8 , Issue.4 , pp. 398-406
    • Wu, C.J.1    Conze, D.B.2    Li, T.3    Srinivasula, S.M.4    Ashwell, J.D.5
  • 148
    • 3943054838 scopus 로고    scopus 로고
    • De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
    • Wertz I.E., O'Rourke K.M., Zhou H., Eby M., Aravind L., Seshagiri S., et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 2004, 430(7000):694-699.
    • (2004) Nature , vol.430 , Issue.7000 , pp. 694-699
    • Wertz, I.E.1    O'Rourke, K.M.2    Zhou, H.3    Eby, M.4    Aravind, L.5    Seshagiri, S.6
  • 149
    • 18844464056 scopus 로고    scopus 로고
    • Identification of the familial cylindromatosis tumour-suppressor gene
    • Bignell G.R., Warren W., Seal S., Takahashi M., Rapley E., Barfoot R., et al. Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet 2000, 25(2):160-165.
    • (2000) Nat Genet , vol.25 , Issue.2 , pp. 160-165
    • Bignell, G.R.1    Warren, W.2    Seal, S.3    Takahashi, M.4    Rapley, E.5    Barfoot, R.6
  • 150
    • 39549106692 scopus 로고    scopus 로고
    • The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module
    • Komander D., Lord C.J., Scheel H., Swift S., Hofmann K., Ashworth A., et al. The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. Mol Cell 2008, 29(4):451-464.
    • (2008) Mol Cell , vol.29 , Issue.4 , pp. 451-464
    • Komander, D.1    Lord, C.J.2    Scheel, H.3    Swift, S.4    Hofmann, K.5    Ashworth, A.6
  • 151
    • 67649366019 scopus 로고    scopus 로고
    • Proteasome inhibitors impair RANKL-induced NF-kappaB activity in osteoclast-like cells via disruption of p62. TRAF6, CYLD, and IkappaBalpha signaling cascades
    • Ang E., Pavlos N.J., Rea S.L., Qi M., Chai T., Walsh J.P., et al. Proteasome inhibitors impair RANKL-induced NF-kappaB activity in osteoclast-like cells via disruption of p62. TRAF6, CYLD, and IkappaBalpha signaling cascades. J Cell Physiol 2009, 220(2):450-459.
    • (2009) J Cell Physiol , vol.220 , Issue.2 , pp. 450-459
    • Ang, E.1    Pavlos, N.J.2    Rea, S.L.3    Qi, M.4    Chai, T.5    Walsh, J.P.6
  • 152
    • 43049124129 scopus 로고    scopus 로고
    • Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice
    • Jin W., Chang M., Paul E.M., Babu G., Lee A.J., Reiley W., et al. Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice. J Clin Invest 2008, 118(5):1858-1866.
    • (2008) J Clin Invest , vol.118 , Issue.5 , pp. 1858-1866
    • Jin, W.1    Chang, M.2    Paul, E.M.3    Babu, G.4    Lee, A.J.5    Reiley, W.6
  • 153
    • 3142771914 scopus 로고    scopus 로고
    • Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response
    • Saccani S., Marazzi I., Beg A.A., Natoli G. Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. J Exp Med 2004, 200(1):107-113.
    • (2004) J Exp Med , vol.200 , Issue.1 , pp. 107-113
    • Saccani, S.1    Marazzi, I.2    Beg, A.A.3    Natoli, G.4
  • 154
    • 0035839450 scopus 로고    scopus 로고
    • A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation
    • Arron J.R., Vologodskaia M., Wong B.R., Naramura M., Kim N., Gu H., et al. A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation. J Biol Chem 2001, 276(32):30011-30017.
    • (2001) J Biol Chem , vol.276 , Issue.32 , pp. 30011-30017
    • Arron, J.R.1    Vologodskaia, M.2    Wong, B.R.3    Naramura, M.4    Kim, N.5    Gu, H.6
  • 155
    • 70349129576 scopus 로고    scopus 로고
    • Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia
    • Nakajima A., Sanjay A., Chiusaroli R., Adapala N.S., Neff L., Itzsteink C., et al. Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia. J Bone Miner Res 2009, 24(7):1162-1172.
    • (2009) J Bone Miner Res , vol.24 , Issue.7 , pp. 1162-1172
    • Nakajima, A.1    Sanjay, A.2    Chiusaroli, R.3    Adapala, N.S.4    Neff, L.5    Itzsteink, C.6
  • 156
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y., Mizushima N., Ueno T., Yamamoto A., Kirisako T., Noda T., et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000, 19(21):5720-5728.
    • (2000) EMBO J , vol.19 , Issue.21 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6
  • 157
    • 27944504351 scopus 로고    scopus 로고
    • P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy G., Lamark T., Brech A., Outzen H., Perander M., Overvatn A., et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 2005, 171(4):603-614.
    • (2005) J Cell Biol , vol.171 , Issue.4 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6
  • 158
    • 0347626252 scopus 로고    scopus 로고
    • Autophagy: a regulated bulk degradation process inside cells
    • Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 2004, 313(2):453-458.
    • (2004) Biochem Biophys Res Commun , vol.313 , Issue.2 , pp. 453-458
    • Yoshimori, T.1
  • 159
    • 33746805387 scopus 로고    scopus 로고
    • Signaling, polyubiquitination, trafficking, and inclusions: sequestosome 1/p62's role in neurodegenerative disease
    • Wooten M.W., Hu X., Babu J.R., Seibenhener M.L., Geetha T., Paine M.G., et al. Signaling, polyubiquitination, trafficking, and inclusions: sequestosome 1/p62's role in neurodegenerative disease. J Biomed Biotechnol 2006, 2006(3):62079.
    • (2006) J Biomed Biotechnol , vol.2006 , Issue.3 , pp. 62079
    • Wooten, M.W.1    Hu, X.2    Babu, J.R.3    Seibenhener, M.L.4    Geetha, T.5    Paine, M.G.6
  • 160
    • 33846702991 scopus 로고    scopus 로고
    • Autophagy, organelles and ageing
    • Terman A., Gustafsson B., Brunk U.T. Autophagy, organelles and ageing. J Pathol 2007, 211(2):134-143.
    • (2007) J Pathol , vol.211 , Issue.2 , pp. 134-143
    • Terman, A.1    Gustafsson, B.2    Brunk, U.T.3
  • 161
    • 65549085701 scopus 로고    scopus 로고
    • Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
    • Jin Z., Li Y., Pitti R., Lawrence D., Pham V.C., Lill J.R., et al. Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 2009, 137(4):721-735.
    • (2009) Cell , vol.137 , Issue.4 , pp. 721-735
    • Jin, Z.1    Li, Y.2    Pitti, R.3    Lawrence, D.4    Pham, V.C.5    Lill, J.R.6
  • 162
    • 77449153351 scopus 로고    scopus 로고
    • Regulation of death receptor signaling by the ubiquitin system
    • Wertz I.E., Dixit V.M. Regulation of death receptor signaling by the ubiquitin system. Cell Death Differ 2010, 17(1):14-24.
    • (2010) Cell Death Differ , vol.17 , Issue.1 , pp. 14-24
    • Wertz, I.E.1    Dixit, V.M.2
  • 163
    • 4544371010 scopus 로고    scopus 로고
    • Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences
    • Hocking L.J., Lucas G.J., Daroszewska A., Cundy T., Nicholson G.C., Donath J., et al. Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences. J Bone Miner Res 2004, 19(7):1122-1127.
    • (2004) J Bone Miner Res , vol.19 , Issue.7 , pp. 1122-1127
    • Hocking, L.J.1    Lucas, G.J.2    Daroszewska, A.3    Cundy, T.4    Nicholson, G.C.5    Donath, J.6
  • 164
    • 0141844580 scopus 로고    scopus 로고
    • Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone
    • Ciani B., Layfield R., Cavey J.R., Sheppard P.W., Searle M.S. Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone. J Biol Chem 2003, 278(39):37409-37412.
    • (2003) J Biol Chem , vol.278 , Issue.39 , pp. 37409-37412
    • Ciani, B.1    Layfield, R.2    Cavey, J.R.3    Sheppard, P.W.4    Searle, M.S.5
  • 165
    • 33646597289 scopus 로고    scopus 로고
    • Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone
    • Cavey J.R., Ralston S.H., Sheppard P.W., Ciani B., Gallagher T.R., Long J.E., et al. Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone. Calcif Tissue Int 2006, 78(5):271-277.
    • (2006) Calcif Tissue Int , vol.78 , Issue.5 , pp. 271-277
    • Cavey, J.R.1    Ralston, S.H.2    Sheppard, P.W.3    Ciani, B.4    Gallagher, T.R.5    Long, J.E.6
  • 166
    • 65549140668 scopus 로고    scopus 로고
    • Characterization of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone
    • Najat D., Garner T., Hagen T., Shaw B., Sheppard P.W., Falchetti A., et al. Characterization of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone. J Bone Miner Res 2009, 24(4):632-642.
    • (2009) J Bone Miner Res , vol.24 , Issue.4 , pp. 632-642
    • Najat, D.1    Garner, T.2    Hagen, T.3    Shaw, B.4    Sheppard, P.W.5    Falchetti, A.6
  • 167
    • 70349101680 scopus 로고    scopus 로고
    • Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding
    • Rea S.L., Walsh J.P., Ward L., Magno A.L., Ward B.K., Shaw B., et al. Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding. J Bone Miner Res 2009, 24(7):1216-1223.
    • (2009) J Bone Miner Res , vol.24 , Issue.7 , pp. 1216-1223
    • Rea, S.L.1    Walsh, J.P.2    Ward, L.3    Magno, A.L.4    Ward, B.K.5    Shaw, B.6
  • 168
    • 33846009075 scopus 로고    scopus 로고
    • Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease
    • Kurihara N., Hiruma Y., Zhou H., Subler M.A., Dempster D.W., Singer F.R., et al. Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. J Clin Invest 2007, 117(1):133-142.
    • (2007) J Clin Invest , vol.117 , Issue.1 , pp. 133-142
    • Kurihara, N.1    Hiruma, Y.2    Zhou, H.3    Subler, M.A.4    Dempster, D.W.5    Singer, F.R.6
  • 169
    • 0442325388 scopus 로고    scopus 로고
    • The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis
    • Duran A., Serrano M., Leitges M., Flores J.M., Picard S., Brown J.P., et al. The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. Dev Cell 2004, 6(2):303-309.
    • (2004) Dev Cell , vol.6 , Issue.2 , pp. 303-309
    • Duran, A.1    Serrano, M.2    Leitges, M.3    Flores, J.M.4    Picard, S.5    Brown, J.P.6
  • 170
    • 56049117643 scopus 로고    scopus 로고
    • A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment
    • Hiruma Y., Kurihara N., Subler M.A., Zhou H., Boykin C.S., Zhang H., et al. A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment. Hum Mol Genet 2008, 17(23):3708-3719.
    • (2008) Hum Mol Genet , vol.17 , Issue.23 , pp. 3708-3719
    • Hiruma, Y.1    Kurihara, N.2    Subler, M.A.3    Zhou, H.4    Boykin, C.S.5    Zhang, H.6
  • 171
    • 78650912040 scopus 로고    scopus 로고
    • Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62(P392L) mutation to Paget's disease
    • Kurihara N., Hiruma Y., Yamana K., Michou L., Rousseau C., Morissette J., et al. Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62(P392L) mutation to Paget's disease. Cell Metab 2011, 13(1):23-34.
    • (2011) Cell Metab , vol.13 , Issue.1 , pp. 23-34
    • Kurihara, N.1    Hiruma, Y.2    Yamana, K.3    Michou, L.4    Rousseau, C.5    Morissette, J.6
  • 172
    • 79959810997 scopus 로고    scopus 로고
    • A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice
    • Daroszewska A., van 't Hof R.J., Rojas J.A., Layfield R., Landao-Basonga E., Rose L., et al. A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice. Hum Mol Genet 2011, 20(14):2734-2744.
    • (2011) Hum Mol Genet , vol.20 , Issue.14 , pp. 2734-2744
    • Daroszewska, A.1    van 't Hof, R.J.2    Rojas, J.A.3    Layfield, R.4    Landao-Basonga, E.5    Rose, L.6
  • 174
    • 61849097834 scopus 로고    scopus 로고
    • Somatic mutations in SQSTM1 detected in affected tissues from patients with sporadic Paget's disease of bone
    • Merchant A., Smielewska M., Patel N., Akunowicz J.D., Saria E.A., Delaney J.D., et al. Somatic mutations in SQSTM1 detected in affected tissues from patients with sporadic Paget's disease of bone. J Bone Miner Res 2009, 24(3):484-494.
    • (2009) J Bone Miner Res , vol.24 , Issue.3 , pp. 484-494
    • Merchant, A.1    Smielewska, M.2    Patel, N.3    Akunowicz, J.D.4    Saria, E.A.5    Delaney, J.D.6
  • 176
    • 84859426900 scopus 로고    scopus 로고
    • Large phenotypic variability of Paget disease of bone caused by the P392L sequestosome1/p62 mutation
    • Laurin N., Morissette J., Raymond V., Brown J.P. Large phenotypic variability of Paget disease of bone caused by the P392L sequestosome1/p62 mutation. Calcif Tissue Int 2003, 72:776.
    • (2003) Calcif Tissue Int , vol.72 , pp. 776
    • Laurin, N.1    Morissette, J.2    Raymond, V.3    Brown, J.P.4
  • 177
    • 70349764552 scopus 로고    scopus 로고
    • The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts
    • Chamoux E., Couture J., Bisson M., Morissette J., Brown J.P., Roux S. The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts. Mol Endocrinol 2009, 23(10):1668-1680.
    • (2009) Mol Endocrinol , vol.23 , Issue.10 , pp. 1668-1680
    • Chamoux, E.1    Couture, J.2    Bisson, M.3    Morissette, J.4    Brown, J.P.5    Roux, S.6
  • 178
    • 79751527853 scopus 로고    scopus 로고
    • Novel SQSTM1 mutations in patients with Paget's disease of bone in an unrelated multiethnic American population
    • Michou L., Morissette J., Gagnon E.R., Marquis A., Dellabadia M., Brown J.P., et al. Novel SQSTM1 mutations in patients with Paget's disease of bone in an unrelated multiethnic American population. Bone 2011, 48(3):456-460.
    • (2011) Bone , vol.48 , Issue.3 , pp. 456-460
    • Michou, L.1    Morissette, J.2    Gagnon, E.R.3    Marquis, A.4    Dellabadia, M.5    Brown, J.P.6
  • 179
    • 34247188567 scopus 로고    scopus 로고
    • Delayed development of Paget's disease in offspring inheriting SQSTM1 mutations
    • Bolland M.J., Tong P.C., Naot D., Callon K.E., Wattie D.J., Gamble G.D., et al. Delayed development of Paget's disease in offspring inheriting SQSTM1 mutations. J Bone Miner Res 2007, 22(3):411-415.
    • (2007) J Bone Miner Res , vol.22 , Issue.3 , pp. 411-415
    • Bolland, M.J.1    Tong, P.C.2    Naot, D.3    Callon, K.E.4    Wattie, D.J.5    Gamble, G.D.6
  • 180
    • 33846479861 scopus 로고    scopus 로고
    • Paget's disease of bone in the French population: novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations
    • Collet C., Michou L., Audran M., Chasseigneaux S., Hilliquin P., Bardin T., et al. Paget's disease of bone in the French population: novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations. J Bone Miner Res 2007, 22(2):310-317.
    • (2007) J Bone Miner Res , vol.22 , Issue.2 , pp. 310-317
    • Collet, C.1    Michou, L.2    Audran, M.3    Chasseigneaux, S.4    Hilliquin, P.5    Bardin, T.6
  • 181
    • 2342493320 scopus 로고    scopus 로고
    • Familial Paget's disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations
    • Eekhoff E.W., Karperien M., Houtsma D., Zwinderman A.H., Dragoiescu C., Kneppers A.L., et al. Familial Paget's disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations. Arthritis Rheum 2004, 50(5):1650-1654.
    • (2004) Arthritis Rheum , vol.50 , Issue.5 , pp. 1650-1654
    • Eekhoff, E.W.1    Karperien, M.2    Houtsma, D.3    Zwinderman, A.H.4    Dragoiescu, C.5    Kneppers, A.L.6
  • 183
    • 79958056647 scopus 로고    scopus 로고
    • Indications for a genetic association of a VCP polymorphism with the pathogenesis of sporadic Paget's disease of bone, but not for TNFSF11 (RANKL) and IL-6 polymorphisms
    • Chung P.Y., Beyens G., de Freitas F., Boonen S., Geusens P., Vanhoenacker F., et al. Indications for a genetic association of a VCP polymorphism with the pathogenesis of sporadic Paget's disease of bone, but not for TNFSF11 (RANKL) and IL-6 polymorphisms. Mol Genet Metab 2011, 103(3):287-292.
    • (2011) Mol Genet Metab , vol.103 , Issue.3 , pp. 287-292
    • Chung, P.Y.1    Beyens, G.2    de Freitas, F.3    Boonen, S.4    Geusens, P.5    Vanhoenacker, F.6
  • 184
    • 31544436590 scopus 로고    scopus 로고
    • Evaluation of the role of Valosin-containing protein in the pathogenesis of familial and sporadic Paget's disease of bone
    • Lucas G.J., Mehta S.G., Hocking L.J., Stewart T.L., Cundy T., Nicholson G.C., et al. Evaluation of the role of Valosin-containing protein in the pathogenesis of familial and sporadic Paget's disease of bone. Bone 2006, 38(2):280-285.
    • (2006) Bone , vol.38 , Issue.2 , pp. 280-285
    • Lucas, G.J.1    Mehta, S.G.2    Hocking, L.J.3    Stewart, T.L.4    Cundy, T.5    Nicholson, G.C.6
  • 185
    • 3042688451 scopus 로고    scopus 로고
    • Vitamin D receptor, oestrogen receptor-alpha and calcium-sensing receptor genotypes, bone mineral density and biochemical markers in Paget's disease of bone
    • Donath J., Speer G., Poor G., Gergely P., Tabak A., Lakatos P. Vitamin D receptor, oestrogen receptor-alpha and calcium-sensing receptor genotypes, bone mineral density and biochemical markers in Paget's disease of bone. Rheumatology (Oxford) 2004, 43(6):692-695.
    • (2004) Rheumatology (Oxford) , vol.43 , Issue.6 , pp. 692-695
    • Donath, J.1    Speer, G.2    Poor, G.3    Gergely, P.4    Tabak, A.5    Lakatos, P.6
  • 187
    • 16644391256 scopus 로고    scopus 로고
    • Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin
    • Daroszewska A., Hocking L.J., McGuigan F.E., Langdahl B., Stone M.D., Cundy T., et al. Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin. J Bone Miner Res 2004, 19(9):1506-1511.
    • (2004) J Bone Miner Res , vol.19 , Issue.9 , pp. 1506-1511
    • Daroszewska, A.1    Hocking, L.J.2    McGuigan, F.E.3    Langdahl, B.4    Stone, M.D.5    Cundy, T.6
  • 188
    • 34548147590 scopus 로고    scopus 로고
    • Identification of sex-specific associations between polymorphisms of the osteoprotegerin gene. TNFRSF11B, and Paget's disease of bone
    • Beyens G., Daroszewska A., de Freitas F., Fransen E., Vanhoenacker F., Verbruggen L., et al. Identification of sex-specific associations between polymorphisms of the osteoprotegerin gene. TNFRSF11B, and Paget's disease of bone. J Bone Miner Res 2007, 22(7):1062-1071.
    • (2007) J Bone Miner Res , vol.22 , Issue.7 , pp. 1062-1071
    • Beyens, G.1    Daroszewska, A.2    de Freitas, F.3    Fransen, E.4    Vanhoenacker, F.5    Verbruggen, L.6
  • 189
    • 70450035725 scopus 로고    scopus 로고
    • Genetic variation in the TNFRSF11A (RANK) gene contributes to the risk to develop sporadic Paget's disease of bone
    • Chung P.Y.J., Beyens G., Riches P.L., Van Wesenbeeck L., Jennes K., Daroszewska A., et al. Genetic variation in the TNFRSF11A (RANK) gene contributes to the risk to develop sporadic Paget's disease of bone. Bone 2009, 44(Suppl 2):S347-S348.
    • (2009) Bone , vol.44 , Issue.SUPPL. 2
    • Chung, P.Y.J.1    Beyens, G.2    Riches, P.L.3    Van Wesenbeeck, L.4    Jennes, K.5    Daroszewska, A.6
  • 190
    • 78649317834 scopus 로고    scopus 로고
    • Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone
    • Chung P.Y., Beyens G., Riches P.L., Van Wesenbeeck L., de Freitas F., Jennes K., et al. Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone. J Bone Miner Res 2010, 25(12):2316-2329.
    • (2010) J Bone Miner Res , vol.25 , Issue.12 , pp. 2316-2329
    • Chung, P.Y.1    Beyens, G.2    Riches, P.L.3    Van Wesenbeeck, L.4    de Freitas, F.5    Jennes, K.6
  • 191
    • 77952884683 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CSF1. OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone
    • Albagha O.M., Visconti M.R., Alonso N., Langston A.L., Cundy T., Dargie R., et al. Genome-wide association study identifies variants at CSF1. OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone. Nat Genet 2010, 42(6):520-524.
    • (2010) Nat Genet , vol.42 , Issue.6 , pp. 520-524
    • Albagha, O.M.1    Visconti, M.R.2    Alonso, N.3    Langston, A.L.4    Cundy, T.5    Dargie, R.6
  • 192
    • 34547924464 scopus 로고    scopus 로고
    • Optineurin negatively regulates TNFalpha-induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP
    • Zhu G., Wu C.J., Zhao Y., Ashwell J.D. Optineurin negatively regulates TNFalpha-induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP. Curr Biol 2007, 17(16):1438-1443.
    • (2007) Curr Biol , vol.17 , Issue.16 , pp. 1438-1443
    • Zhu, G.1    Wu, C.J.2    Zhao, Y.3    Ashwell, J.D.4
  • 193
    • 78649320390 scopus 로고    scopus 로고
    • The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1. OPTN, TM7SF4, and TNFRSF11A genes
    • Chung P.Y., Beyens G., Boonen S., Papapoulos S., Geusens P., Karperien M., et al. The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1. OPTN, TM7SF4, and TNFRSF11A genes. Hum Genet 2010, 128(6):615-626.
    • (2010) Hum Genet , vol.128 , Issue.6 , pp. 615-626
    • Chung, P.Y.1    Beyens, G.2    Boonen, S.3    Papapoulos, S.4    Geusens, P.5    Karperien, M.6
  • 194
    • 23744459835 scopus 로고    scopus 로고
    • DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells
    • Yagi M., Miyamoto T., Sawatani Y., Iwamoto K., Hosogane N., Fujita N., et al. DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med 2005, 202(3):345-351.
    • (2005) J Exp Med , vol.202 , Issue.3 , pp. 345-351
    • Yagi, M.1    Miyamoto, T.2    Sawatani, Y.3    Iwamoto, K.4    Hosogane, N.5    Fujita, N.6
  • 195
    • 79959745220 scopus 로고    scopus 로고
    • Genome-wide association identifies three new susceptibility loci for Paget's disease of bone
    • Albagha O.M., Wani S.E., Visconti M.R., Alonso N., Goodman K., Brandi M.L., et al. Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. Nat Genet 2011, 10.1038/ng.845.
    • (2011) Nat Genet
    • Albagha, O.M.1    Wani, S.E.2    Visconti, M.R.3    Alonso, N.4    Goodman, K.5    Brandi, M.L.6
  • 196
    • 78549251353 scopus 로고    scopus 로고
    • Functional interaction between sequestosome-1/p62 and autophagy-linked FYVE-containing protein WDFY3 in human osteoclasts
    • Hocking L.J., Mellis D.J., McCabe P.S., Helfrich M.H., Rogers M.J. Functional interaction between sequestosome-1/p62 and autophagy-linked FYVE-containing protein WDFY3 in human osteoclasts. Biochem Biophys Res Commun 2010, 402(3):543-548.
    • (2010) Biochem Biophys Res Commun , vol.402 , Issue.3 , pp. 543-548
    • Hocking, L.J.1    Mellis, D.J.2    McCabe, P.S.3    Helfrich, M.H.4    Rogers, M.J.5
  • 197
    • 4544256756 scopus 로고    scopus 로고
    • Cytoplasmic PML function in TGF-beta signalling
    • Lin H.K., Bergmann S., Pandolfi P.P. Cytoplasmic PML function in TGF-beta signalling. Nature 2004, 431(7005):205-211.
    • (2004) Nature , vol.431 , Issue.7005 , pp. 205-211
    • Lin, H.K.1    Bergmann, S.2    Pandolfi, P.P.3
  • 198
    • 74849098404 scopus 로고    scopus 로고
    • Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210
    • Smits P., Bolton A.D., Funari V., Hong M., Boyden E.D., Lu L., et al. Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210. N Engl J Med 2010, 362(3):206-216.
    • (2010) N Engl J Med , vol.362 , Issue.3 , pp. 206-216
    • Smits, P.1    Bolton, A.D.2    Funari, V.3    Hong, M.4    Boyden, E.D.5    Lu, L.6
  • 199
    • 56749131629 scopus 로고    scopus 로고
    • Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin
    • Hennies H.C., Kornak U., Zhang H., Egerer J., Zhang X., Seifert W., et al. Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin. Nat Genet 2008, 40(12):1410-1412.
    • (2008) Nat Genet , vol.40 , Issue.12 , pp. 1410-1412
    • Hennies, H.C.1    Kornak, U.2    Zhang, H.3    Egerer, J.4    Zhang, X.5    Seifert, W.6
  • 200
    • 33645987648 scopus 로고    scopus 로고
    • Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation
    • Sun S.G., Lau Y.S., Itonaga I., Sabokbar A., Athanasou N.A. Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation. J Pathol 2006, 209(1):114-120.
    • (2006) J Pathol , vol.209 , Issue.1 , pp. 114-120
    • Sun, S.G.1    Lau, Y.S.2    Itonaga, I.3    Sabokbar, A.4    Athanasou, N.A.5
  • 201
    • 70349324551 scopus 로고    scopus 로고
    • The effect of zoledronic acid on serum dickkopf-1, osteoprotegerin, and RANKL in patients with Paget's disease of bone
    • Polyzos S.A., Anastasilakis A.D., Efstathiadou Z., Kita M., Litsas I., Avramidis A., et al. The effect of zoledronic acid on serum dickkopf-1, osteoprotegerin, and RANKL in patients with Paget's disease of bone. Horm Metab Res 2009, 41(11):846-850.
    • (2009) Horm Metab Res , vol.41 , Issue.11 , pp. 846-850
    • Polyzos, S.A.1    Anastasilakis, A.D.2    Efstathiadou, Z.3    Kita, M.4    Litsas, I.5    Avramidis, A.6
  • 203
    • 33846505388 scopus 로고    scopus 로고
    • Differential gene expression in cultured osteoblasts and bone marrow stromal cells from patients with Paget's disease of bone
    • Naot D., Bava U., Matthews B., Callon K.E., Gamble G.D., Black M., et al. Differential gene expression in cultured osteoblasts and bone marrow stromal cells from patients with Paget's disease of bone. J Bone Miner Res 2007, 22(2):298-309.
    • (2007) J Bone Miner Res , vol.22 , Issue.2 , pp. 298-309
    • Naot, D.1    Bava, U.2    Matthews, B.3    Callon, K.E.4    Gamble, G.D.5    Black, M.6
  • 204
    • 0028044531 scopus 로고
    • Interleukin-6. IL-6 receptor, and IL-6 nuclear factor gene expression in Paget's disease
    • Hoyland J.A., Freemont A.J., Sharpe P.T. Interleukin-6. IL-6 receptor, and IL-6 nuclear factor gene expression in Paget's disease. J Bone Miner Res 1994, 9(1):75-80.
    • (1994) J Bone Miner Res , vol.9 , Issue.1 , pp. 75-80
    • Hoyland, J.A.1    Freemont, A.J.2    Sharpe, P.T.3
  • 205
    • 0014518639 scopus 로고
    • Paget's sarcoma of bone. A study of eighty cases from the Bristol and the Leeds bone tumour registries
    • Price C.H., Goldie W. Paget's sarcoma of bone. A study of eighty cases from the Bristol and the Leeds bone tumour registries. J Bone Joint Surg Br 1969, 51(2):205-224.
    • (1969) J Bone Joint Surg Br , vol.51 , Issue.2 , pp. 205-224
    • Price, C.H.1    Goldie, W.2
  • 206
    • 0020754426 scopus 로고
    • Sarcoma complicating Paget's disease of bone. A clinicopathological study of 62 cases
    • Schajowicz F., Santini Araujo E., Berenstein M. Sarcoma complicating Paget's disease of bone. A clinicopathological study of 62 cases. J Bone Joint Surg Br 1983, 65(3):299-307.
    • (1983) J Bone Joint Surg Br , vol.65 , Issue.3 , pp. 299-307
    • Schajowicz, F.1    Santini Araujo, E.2    Berenstein, M.3
  • 207
    • 0025771583 scopus 로고
    • Sarcoma in Paget disease of bone: clinical, radiologic, and pathologic features in 22 cases
    • Moore T.E., King A.R., Kathol M.H., El-Khoury G.Y., Palmer R., Downey P.R. Sarcoma in Paget disease of bone: clinical, radiologic, and pathologic features in 22 cases. AJR Am J Roentgenol 1991, 156(6):1199-1203.
    • (1991) AJR Am J Roentgenol , vol.156 , Issue.6 , pp. 1199-1203
    • Moore, T.E.1    King, A.R.2    Kathol, M.H.3    El-Khoury, G.Y.4    Palmer, R.5    Downey, P.R.6
  • 209
    • 63449118087 scopus 로고    scopus 로고
    • Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance. Epidemiology, and End Results Program
    • Mirabello L., Troisi R.J., Savage S.A. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance. Epidemiology, and End Results Program. Cancer 2009, 115(7):1531-1543.
    • (2009) Cancer , vol.115 , Issue.7 , pp. 1531-1543
    • Mirabello, L.1    Troisi, R.J.2    Savage, S.A.3
  • 211
    • 0013635361 scopus 로고
    • The incidence of osteogenic sarcoma in South-West England and its relationship to Paget's disease of bone
    • Price C.H. The incidence of osteogenic sarcoma in South-West England and its relationship to Paget's disease of bone. J Bone Joint Surg Br 1962, 44B:366-376.
    • (1962) J Bone Joint Surg Br , vol.44 B , pp. 366-376
    • Price, C.H.1
  • 212
    • 66149135224 scopus 로고    scopus 로고
    • International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons
    • Mirabello L., Troisi R.J., Savage S.A. International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons. Int J Cancer 2009, 125(1):229-234.
    • (2009) Int J Cancer , vol.125 , Issue.1 , pp. 229-234
    • Mirabello, L.1    Troisi, R.J.2    Savage, S.A.3
  • 213
    • 59649085293 scopus 로고    scopus 로고
    • Sarcoma arising in Paget's disease of bone: declining incidence and increasing age at presentation
    • Mangham D.C., Davie M.W., Grimer R.J. Sarcoma arising in Paget's disease of bone: declining incidence and increasing age at presentation. Bone 2009, 44(3):431-436.
    • (2009) Bone , vol.44 , Issue.3 , pp. 431-436
    • Mangham, D.C.1    Davie, M.W.2    Grimer, R.J.3
  • 215
    • 0008711249 scopus 로고
    • Studies of Paget's disease (osteitis deformans)
    • Lake M. Studies of Paget's disease (osteitis deformans). J Bone Joint Surg Br 1951, 33B(3):323-335.
    • (1951) J Bone Joint Surg Br , vol.33 B , Issue.3 , pp. 323-335
    • Lake, M.1
  • 218
    • 0025860711 scopus 로고
    • Multiple giant cell tumors and Paget disease of bone: radiographic and clinical correlations
    • Potter H.G., Schneider R., Ghelman B., Healey J.H., Lane J.M. Multiple giant cell tumors and Paget disease of bone: radiographic and clinical correlations. Radiology 1991, 180(1):261-264.
    • (1991) Radiology , vol.180 , Issue.1 , pp. 261-264
    • Potter, H.G.1    Schneider, R.2    Ghelman, B.3    Healey, J.H.4    Lane, J.M.5
  • 219
    • 0028031320 scopus 로고
    • Upregulation of c-fos protooncogene expression in pagetic osteoclasts
    • Hoyland J., Sharpe P.T. Upregulation of c-fos protooncogene expression in pagetic osteoclasts. J Bone Miner Res 1994, 9(8):1191-1194.
    • (1994) J Bone Miner Res , vol.9 , Issue.8 , pp. 1191-1194
    • Hoyland, J.1    Sharpe, P.T.2
  • 221
    • 0025288793 scopus 로고
    • An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
    • Haber D.A., Buckler A.J., Glaser T., Call K.M., Pelletier J., Sohn R.L., et al. An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell 1990, 61(7):1257-1269.
    • (1990) Cell , vol.61 , Issue.7 , pp. 1257-1269
    • Haber, D.A.1    Buckler, A.J.2    Glaser, T.3    Call, K.M.4    Pelletier, J.5    Sohn, R.L.6
  • 222
    • 0025297599 scopus 로고
    • Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients
    • Wallace M.R., Marchuk D.A., Andersen L.B., Letcher R., Odeh H.M., Saulino A.M., et al. Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. Science 1990, 249(4965):181-186.
    • (1990) Science , vol.249 , Issue.4965 , pp. 181-186
    • Wallace, M.R.1    Marchuk, D.A.2    Andersen, L.B.3    Letcher, R.4    Odeh, H.M.5    Saulino, A.M.6
  • 223
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • Friend S.H., Bernards R., Rogelj S., Weinberg R.A., Rapaport J.M., Albert D.M., et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 1986, 323(6089):643-646.
    • (1986) Nature , vol.323 , Issue.6089 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3    Weinberg, R.A.4    Rapaport, J.M.5    Albert, D.M.6
  • 224
    • 0023222707 scopus 로고
    • Structural evidence for the authenticity of the human retinoblastoma gene
    • Fung Y.K., Murphree A.L., T'Ang A., Qian J., Hinrichs S.H., Benedict W.F. Structural evidence for the authenticity of the human retinoblastoma gene. Science 1987, 236(4809):1657-1661.
    • (1987) Science , vol.236 , Issue.4809 , pp. 1657-1661
    • Fung, Y.K.1    Murphree, A.L.2    T'Ang, A.3    Qian, J.4    Hinrichs, S.H.5    Benedict, W.F.6
  • 225
    • 0022402666 scopus 로고
    • Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition
    • Hansen M.F., Koufos A., Gallie B.L., Phillips R.A., Fodstad O., Brogger A., et al. Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition. Proc Natl Acad Sci USA 1985, 82(18):6216-6220.
    • (1985) Proc Natl Acad Sci USA , vol.82 , Issue.18 , pp. 6216-6220
    • Hansen, M.F.1    Koufos, A.2    Gallie, B.L.3    Phillips, R.A.4    Fodstad, O.5    Brogger, A.6
  • 226
    • 0026647228 scopus 로고
    • Allelotype analysis in osteosarcomas: frequent allele loss on 3q, 13q, 17p, and 18q
    • Yamaguchi T., Toguchida J., Yamamuro T., Kotoura Y., Takada N., Kawaguchi N., et al. Allelotype analysis in osteosarcomas: frequent allele loss on 3q, 13q, 17p, and 18q. Cancer Res 1992, 52(9):2419-2423.
    • (1992) Cancer Res , vol.52 , Issue.9 , pp. 2419-2423
    • Yamaguchi, T.1    Toguchida, J.2    Yamamuro, T.3    Kotoura, Y.4    Takada, N.5    Kawaguchi, N.6
  • 227
    • 0032231715 scopus 로고    scopus 로고
    • Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone
    • Nellissery M.J., Padalecki S.S., Brkanac Z., Singer F.R., Roodman G.D., Unni K.K., et al. Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone. Am J Hum Genet 1998, 63(3):817-824.
    • (1998) Am J Hum Genet , vol.63 , Issue.3 , pp. 817-824
    • Nellissery, M.J.1    Padalecki, S.S.2    Brkanac, Z.3    Singer, F.R.4    Roodman, G.D.5    Unni, K.K.6
  • 228
  • 229
    • 65249167488 scopus 로고    scopus 로고
    • Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice
    • Kansara M., Tsang M., Kodjabachian L., Sims N.A., Trivett M.K., Ehrich M., et al. Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice. J Clin Invest 2009, 119(4):837-851.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 837-851
    • Kansara, M.1    Tsang, M.2    Kodjabachian, L.3    Sims, N.A.4    Trivett, M.K.5    Ehrich, M.6
  • 231
    • 46649090289 scopus 로고    scopus 로고
    • Management of patients with Paget's disease: a consensus document of the Belgian Bone Club
    • Devogelaer J.P., Bergmann P., Body J.J., Boutsen Y., Goemaere S., Kaufman J.M., et al. Management of patients with Paget's disease: a consensus document of the Belgian Bone Club. Osteoporos Int 2008, 19(8):1109-1117.
    • (2008) Osteoporos Int , vol.19 , Issue.8 , pp. 1109-1117
    • Devogelaer, J.P.1    Bergmann, P.2    Body, J.J.3    Boutsen, Y.4    Goemaere, S.5    Kaufman, J.M.6
  • 232
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
    • Russell R.G., Watts N.B., Ebetino F.H., Rogers M.J. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int 2008, 19(6):733-759.
    • (2008) Osteoporos Int , vol.19 , Issue.6 , pp. 733-759
    • Russell, R.G.1    Watts, N.B.2    Ebetino, F.H.3    Rogers, M.J.4
  • 233
    • 0015937733 scopus 로고
    • Influence of disodium etidronate on clinical and laboratory manifestations of Paget's disease of bone (osteitis deformans)
    • Altman R.D., Johnston C.C., Khairi M.R., Wellman H., Serafini A.N., Sankey R.R. Influence of disodium etidronate on clinical and laboratory manifestations of Paget's disease of bone (osteitis deformans). N Engl J Med 1973, 289(26):1379-1384.
    • (1973) N Engl J Med , vol.289 , Issue.26 , pp. 1379-1384
    • Altman, R.D.1    Johnston, C.C.2    Khairi, M.R.3    Wellman, H.4    Serafini, A.N.5    Sankey, R.R.6
  • 234
    • 0023282832 scopus 로고
    • The effect of 1 alpha-hydroxyvitamin D3 on the mineralization defect in disodium etidronate-treated Paget's disease-a double-blind randomized clinical study
    • Ralston S.H., Boyce B.F., Cowan R.A., Fogelman I., Smith M.L., Jenkins A., et al. The effect of 1 alpha-hydroxyvitamin D3 on the mineralization defect in disodium etidronate-treated Paget's disease-a double-blind randomized clinical study. J Bone Miner Res 1987, 2(1):5-12.
    • (1987) J Bone Miner Res , vol.2 , Issue.1 , pp. 5-12
    • Ralston, S.H.1    Boyce, B.F.2    Cowan, R.A.3    Fogelman, I.4    Smith, M.L.5    Jenkins, A.6
  • 235
    • 0030826122 scopus 로고    scopus 로고
    • A double-blind, multicentre, placebo-controlled study of tiludronate in Paget's disease of bone
    • Fraser W.D., Stamp T.C., Creek R.A., Sawyer J.P., Picot C. A double-blind, multicentre, placebo-controlled study of tiludronate in Paget's disease of bone. Postgrad Med J 1997, 73(862):496-502.
    • (1997) Postgrad Med J , vol.73 , Issue.862 , pp. 496-502
    • Fraser, W.D.1    Stamp, T.C.2    Creek, R.A.3    Sawyer, J.P.4    Picot, C.5
  • 236
    • 24044431619 scopus 로고    scopus 로고
    • Comparison of a single infusion of zoledronic acid with risedronate for Paget's disease
    • Reid I.R., Miller P., Lyles K., Fraser W., Brown J.P., Saidi Y., et al. Comparison of a single infusion of zoledronic acid with risedronate for Paget's disease. N Engl J Med 2005, 353(9):898-908.
    • (2005) N Engl J Med , vol.353 , Issue.9 , pp. 898-908
    • Reid, I.R.1    Miller, P.2    Lyles, K.3    Fraser, W.4    Brown, J.P.5    Saidi, Y.6
  • 237
    • 77953424429 scopus 로고    scopus 로고
    • Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone
    • Langston A.L., Campbell M.K., Fraser W.D., MacLennan G.S., Selby P.L., Ralston S.H. Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone. J Bone Miner Res 2010, 25(1):20-31.
    • (2010) J Bone Miner Res , vol.25 , Issue.1 , pp. 20-31
    • Langston, A.L.1    Campbell, M.K.2    Fraser, W.D.3    MacLennan, G.S.4    Selby, P.L.5    Ralston, S.H.6
  • 238
    • 79954446628 scopus 로고    scopus 로고
    • Proposed new approach for treating Paget's disease of bone
    • Mahmood W., McKenna M.J. Proposed new approach for treating Paget's disease of bone. Ir J Med Sci 2010, 180(1):121-124.
    • (2010) Ir J Med Sci , vol.180 , Issue.1 , pp. 121-124
    • Mahmood, W.1    McKenna, M.J.2
  • 239
    • 25844504632 scopus 로고    scopus 로고
    • Effect of osteoporosis treatments on risk of non-vertebral fractures: review and meta-analysis of intention-to-treat studies
    • Boonen S., Laan R.F., Barton I.P., Watts N.B. Effect of osteoporosis treatments on risk of non-vertebral fractures: review and meta-analysis of intention-to-treat studies. Osteoporos Int 2005, 16(10):1291-1298.
    • (2005) Osteoporos Int , vol.16 , Issue.10 , pp. 1291-1298
    • Boonen, S.1    Laan, R.F.2    Barton, I.P.3    Watts, N.B.4
  • 240
    • 79952464694 scopus 로고    scopus 로고
    • Zoledronic acid: clinical utility and patient considerations in osteoporosis and low bone mass
    • Hamdy R.C. Zoledronic acid: clinical utility and patient considerations in osteoporosis and low bone mass. Drug Des Devel Ther 2010, 4:321-335.
    • (2010) Drug Des Devel Ther , vol.4 , pp. 321-335
    • Hamdy, R.C.1
  • 241
    • 78650729974 scopus 로고    scopus 로고
    • Zoledronic acid infusion for prevention and treatment of osteoporosis
    • Sunyecz J.A. Zoledronic acid infusion for prevention and treatment of osteoporosis. Int J Womens Health 2010, 2:353-360.
    • (2010) Int J Womens Health , vol.2 , pp. 353-360
    • Sunyecz, J.A.1
  • 242
    • 79955580771 scopus 로고    scopus 로고
    • Once-yearly zoledronic acid and days of disability, bed rest and back pain: Randomised controlled HORIZON pivotal fracture trial
    • Cauley J.A., Black D., Boonen S., Cummings S.R., Mesenbrink P., Palermo L., et al. Once-yearly zoledronic acid and days of disability, bed rest and back pain: Randomised controlled HORIZON pivotal fracture trial. J Bone Miner Res 2010, 10.1002/jbmr.292.
    • (2010) J Bone Miner Res
    • Cauley, J.A.1    Black, D.2    Boonen, S.3    Cummings, S.R.4    Mesenbrink, P.5    Palermo, L.6
  • 243
    • 33847771427 scopus 로고    scopus 로고
    • Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis
    • Daubine F., Le Gall C., Gasser J., Green J., Clezardin P. Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis. J Natl Cancer Inst 2007, 99(4):322-330.
    • (2007) J Natl Cancer Inst , vol.99 , Issue.4 , pp. 322-330
    • Daubine, F.1    Le Gall, C.2    Gasser, J.3    Green, J.4    Clezardin, P.5
  • 244
    • 1642374858 scopus 로고    scopus 로고
    • Multiple myeloma
    • Sirohi B., Powles R. Multiple myeloma. Lancet 2004, 363(9412):875-887.
    • (2004) Lancet , vol.363 , Issue.9412 , pp. 875-887
    • Sirohi, B.1    Powles, R.2
  • 245
    • 20044389681 scopus 로고    scopus 로고
    • Bisphosphonates in breast cancer
    • Coleman R.E. Bisphosphonates in breast cancer. Ann Oncol 2005, 16(5):687-695.
    • (2005) Ann Oncol , vol.16 , Issue.5 , pp. 687-695
    • Coleman, R.E.1
  • 246
    • 18544374984 scopus 로고    scopus 로고
    • The role of bisphosphonates in the treatment of prostate cancer
    • Parker C.C. The role of bisphosphonates in the treatment of prostate cancer. BJU Int 2005, 95(7):935-938.
    • (2005) BJU Int , vol.95 , Issue.7 , pp. 935-938
    • Parker, C.C.1
  • 247
    • 49049100911 scopus 로고    scopus 로고
    • Efficacy of the third-generation bisphosphonate risedronate alone and in combination with anticancer drugs against osteosarcoma cell lines
    • Murayama T., Kawasoe Y., Yamashita Y., Ueno Y., Minami S., Yokouchi M., et al. Efficacy of the third-generation bisphosphonate risedronate alone and in combination with anticancer drugs against osteosarcoma cell lines. Anticancer Res 2008, 28(4B):2147-2154.
    • (2008) Anticancer Res , vol.28 , Issue.4 B , pp. 2147-2154
    • Murayama, T.1    Kawasoe, Y.2    Yamashita, Y.3    Ueno, Y.4    Minami, S.5    Yokouchi, M.6
  • 248
    • 69249136273 scopus 로고    scopus 로고
    • Risedronate inhibits human osteosarcoma cell invasion
    • Xin Z.F., Kim Y.K., Jung S.T. Risedronate inhibits human osteosarcoma cell invasion. J Exp Clin Cancer Res 2009, 28:105.
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 105
    • Xin, Z.F.1    Kim, Y.K.2    Jung, S.T.3
  • 249
    • 0036338869 scopus 로고    scopus 로고
    • What the gastroenterologist should know about the gastrointestinal safety profiles of bisphosphonates
    • Graham D.Y. What the gastroenterologist should know about the gastrointestinal safety profiles of bisphosphonates. Dig Dis Sci 2002, 47(8):1665-1678.
    • (2002) Dig Dis Sci , vol.47 , Issue.8 , pp. 1665-1678
    • Graham, D.Y.1
  • 250
    • 0033851184 scopus 로고    scopus 로고
    • Endoscopic comparison of esophageal and gastroduodenal effects of risedronate and alendronate in postmenopausal women
    • Lanza F.L., Hunt R.H., Thomson A.B., Provenza J.M., Blank M.A. Endoscopic comparison of esophageal and gastroduodenal effects of risedronate and alendronate in postmenopausal women. Gastroenterology 2000, 119(3):631-638.
    • (2000) Gastroenterology , vol.119 , Issue.3 , pp. 631-638
    • Lanza, F.L.1    Hunt, R.H.2    Thomson, A.B.3    Provenza, J.M.4    Blank, M.A.5
  • 251
    • 0036733730 scopus 로고    scopus 로고
    • 14 day endoscopy study comparing risedronate and alendronate in postmenopausal women stratified by Helicobacter pylori status
    • Thomson A.B., Marshall J.K., Hunt R.H., Provenza J.M., Lanza F.L., Royer M.G., et al. 14 day endoscopy study comparing risedronate and alendronate in postmenopausal women stratified by Helicobacter pylori status. J Rheumatol 2002, 29(9):1965-1974.
    • (2002) J Rheumatol , vol.29 , Issue.9 , pp. 1965-1974
    • Thomson, A.B.1    Marshall, J.K.2    Hunt, R.H.3    Provenza, J.M.4    Lanza, F.L.5    Royer, M.G.6
  • 253
    • 36549048808 scopus 로고    scopus 로고
    • Bisphosphonates and γδ T-cells: new insights into old drugs
    • Thompson K., Michael J.R. Bisphosphonates and γδ T-cells: new insights into old drugs. BoneKEy-Osteovision 2006, 3(8):5-13.
    • (2006) BoneKEy-Osteovision , vol.3 , Issue.8 , pp. 5-13
    • Thompson, K.1    Michael, J.R.2
  • 254
    • 1642526540 scopus 로고    scopus 로고
    • Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro
    • Thompson K., Rogers M.J. Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. J Bone Miner Res 2004, 19(2):278-288.
    • (2004) J Bone Miner Res , vol.19 , Issue.2 , pp. 278-288
    • Thompson, K.1    Rogers, M.J.2
  • 255
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research
    • Khosla S., Burr D., Cauley J., Dempster D.W., Ebeling P.R., Felsenberg D., et al. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2007, 22(10):1479-1491.
    • (2007) J Bone Miner Res , vol.22 , Issue.10 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3    Dempster, D.W.4    Ebeling, P.R.5    Felsenberg, D.6
  • 256
    • 77952428207 scopus 로고    scopus 로고
    • Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings
    • Hoefert S., Schmitz I., Tannapfel A., Eufinger H. Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings. Clin Oral Investig 2010, 14(3):271-284.
    • (2010) Clin Oral Investig , vol.14 , Issue.3 , pp. 271-284
    • Hoefert, S.1    Schmitz, I.2    Tannapfel, A.3    Eufinger, H.4
  • 257
    • 70350344949 scopus 로고    scopus 로고
    • Mandibular necrosis in beagle dogs treated with bisphosphonates
    • Burr D.B., Allen M.R. Mandibular necrosis in beagle dogs treated with bisphosphonates. Orthod Craniofac Res 2009, 12(3):221-228.
    • (2009) Orthod Craniofac Res , vol.12 , Issue.3 , pp. 221-228
    • Burr, D.B.1    Allen, M.R.2
  • 258
    • 47749144029 scopus 로고    scopus 로고
    • Postmarketing surveillance rates of uveitis and scleritis with bisphosphonates among a national veteran cohort
    • French D.D., Margo C.E. Postmarketing surveillance rates of uveitis and scleritis with bisphosphonates among a national veteran cohort. Retina 2008, 28(6):889-893.
    • (2008) Retina , vol.28 , Issue.6 , pp. 889-893
    • French, D.D.1    Margo, C.E.2
  • 259
    • 0037309091 scopus 로고    scopus 로고
    • Scleritis and other ocular side effects associated with pamidronate disodium
    • Fraunfelder F.W., Fraunfelder F.T., Jensvold B. Scleritis and other ocular side effects associated with pamidronate disodium. Am J Ophthalmol 2003, 135(2):219-222.
    • (2003) Am J Ophthalmol , vol.135 , Issue.2 , pp. 219-222
    • Fraunfelder, F.W.1    Fraunfelder, F.T.2    Jensvold, B.3
  • 260
    • 33845371043 scopus 로고    scopus 로고
    • Corneal graft rejection precipitated by uveitis secondary to alendronate sodium therapy
    • Richards J.C., Wiffen S.J. Corneal graft rejection precipitated by uveitis secondary to alendronate sodium therapy. Cornea 2006, 25(9):1100-1101.
    • (2006) Cornea , vol.25 , Issue.9 , pp. 1100-1101
    • Richards, J.C.1    Wiffen, S.J.2
  • 262
    • 0035007762 scopus 로고    scopus 로고
    • Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate
    • Markowitz G.S., Appel G.B., Fine P.L., Fenves A.Z., Loon N.R., Jagannath S., et al. Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate. J Am Soc Nephrol 2001, 12(6):1164-1172.
    • (2001) J Am Soc Nephrol , vol.12 , Issue.6 , pp. 1164-1172
    • Markowitz, G.S.1    Appel, G.B.2    Fine, P.L.3    Fenves, A.Z.4    Loon, N.R.5    Jagannath, S.6
  • 263
    • 77953672623 scopus 로고    scopus 로고
    • Denosumab
    • Pageau S.C. Denosumab. MAbs 2009, 1(3):210-215.
    • (2009) MAbs , vol.1 , Issue.3 , pp. 210-215
    • Pageau, S.C.1
  • 264
    • 79951689707 scopus 로고    scopus 로고
    • Effect of denosumab on bone mineral density and biochemical markers of bone turnover: six-year results of a phase 2 clinical trial
    • Miller P.D., Wagman R.B., Peacock M., Lewiecki E.M., Bolognese M.A., Weinstein R.L., et al. Effect of denosumab on bone mineral density and biochemical markers of bone turnover: six-year results of a phase 2 clinical trial. J Clin Endocrinol Metab 2011, 96(2):394-402.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.2 , pp. 394-402
    • Miller, P.D.1    Wagman, R.B.2    Peacock, M.3    Lewiecki, E.M.4    Bolognese, M.A.5    Weinstein, R.L.6
  • 265
    • 79952698455 scopus 로고    scopus 로고
    • Denosumab and bisphosphonates: Different mechanisms of action and effects
    • Baron R., Ferrari S., Russell R.G. Denosumab and bisphosphonates: Different mechanisms of action and effects. Bone 2011, 48(4):677-692.
    • (2011) Bone , vol.48 , Issue.4 , pp. 677-692
    • Baron, R.1    Ferrari, S.2    Russell, R.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.