메뉴 건너뛰기




Volumn 119, Issue 11, 2009, Pages 3329-3339

Autophagy regulates adipose mass and differentiation in mice

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; FATTY ACID; PROTEIN ATG 7; UNCLASSIFIED DRUG;

EID: 70449448312     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI39228     Document Type: Article
Times cited : (667)

References (44)
  • 1
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman, B.M., and Flier, J.S. 2001. Obesity and the regulation of energy balance. Cell. 104:531-543.
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 2
    • 64349105205 scopus 로고    scopus 로고
    • Identification and importance of brown adipose tissue in adult humans
    • Cypess, A.M., et al. 2009. Identification and importance of brown adipose tissue in adult humans. N. Engl. J. Med. 360:1509-1517.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 1509-1517
    • Cypess, A.M.1
  • 3
    • 64349095231 scopus 로고    scopus 로고
    • Cold-activated brown adipose tissue in healthy men
    • Marken Lichtenbelt, W.D., et al. 2009. Cold-activated brown adipose tissue in healthy men. N. Engl. J. Med. 360:1500-1508.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 1500-1508
    • Marken Lichtenbelt, W.D.1
  • 5
    • 64349123664 scopus 로고    scopus 로고
    • Functional brown adipose tissue in healthy adults
    • Virtanen, K.A., et al. 2009. Functional brown adipose tissue in healthy adults. N. Engl. J. Med. 360:1518-1525.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 1518-1525
    • Virtanen, K.A.1
  • 6
    • 35348874911 scopus 로고    scopus 로고
    • Developmental Origin of Fat: Tracking Obesity to Its Source
    • DOI 10.1016/j.cell.2007.10.004, PII S009286740701272X
    • Gesta, S., Tseng, Y.H., and Kahn, C.R. 2007. Developmental origin of fat: tracking obesity to its source. Cell. 131:242-256. (Pubitemid 47576146)
    • (2007) Cell , vol.131 , Issue.2 , pp. 242-256
    • Gesta, S.1    Tseng, Y.-H.2    Kahn, C.R.3
  • 7
    • 0344738018 scopus 로고    scopus 로고
    • Conversion from white to brown adipocytes: A strategy for the control of fat mass?
    • DOI 10.1016/j.tem.2003.10.001
    • Tiraby, C., and Langin, D. 2003. Conversion from white to brown adipocytes: a strategy for the control of fat mass? Trends Endocrinol. Metab. 14:439-441. (Pubitemid 37517342)
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , Issue.10 , pp. 439-441
    • Tiraby, C.1    Langin, D.2
  • 8
    • 33748366392 scopus 로고    scopus 로고
    • Regulatory circuits controlling white versus brown adipocyte differentiation
    • DOI 10.1042/BJ20060402
    • Hansen, J.B., and Kristiansen, K. 2006. Regulatory circuits controlling white versus brown adipocyte differentiation. Biochem. J. 398:153-168. (Pubitemid 44338472)
    • (2006) Biochemical Journal , vol.398 , Issue.2 , pp. 153-168
    • Hansen, J.B.1    Kristiansen, K.2
  • 9
    • 44849132591 scopus 로고    scopus 로고
    • Dynamics of fat cell turnover in humans
    • Spalding, K.L., et al. 2008. Dynamics of fat cell turnover in humans. Nature. 453:783-787.
    • (2008) Nature , vol.453 , pp. 783-787
    • Spalding, K.L.1
  • 10
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/ skeletal muscle switch
    • Seale, P., et al. 2008. PRDM16 controls a brown fat/ skeletal muscle switch. Nature. 454:961-967.
    • (2008) Nature , vol.454 , pp. 961-967
    • Seale, P.1
  • 11
    • 34248372084 scopus 로고    scopus 로고
    • Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
    • Timmons, J.A., et al. 2007. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc. Natl. Acad. Sci. U. S. A. 104:4401-4406.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 4401-4406
    • Timmons, J.A.1
  • 12
    • 51449085299 scopus 로고    scopus 로고
    • The role of autophagy in mammalian development: Cell makeover rather than cell death
    • Cecconi, F., and Levine, B. 2008. The role of autophagy in mammalian development: cell makeover rather than cell death. Dev. Cell. 15:344-357.
    • (2008) Dev. Cell. , vol.15 , pp. 344-357
    • Cecconi, F.1    Levine, B.2
  • 13
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima, N., and Yoshimori, T. 2007. How to interpret LC3 immunoblotting. Autophagy. 3:542-545.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 14
    • 1842279106 scopus 로고
    • Expression of specific mRNAs during adipose differentiation: Identification of an mRNA encoding a homologue of myelin P2 protein
    • Bernlohr, D.A., Angus, C.W., Lane, M.D., Bolanowski, M.A., and Kelly, T.J., Jr. 1984. Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc. Natl. Acad. Sci. U. S. A. 81:5468-5472.
    • (1984) Proc. Natl. Acad. Sci. U. S. A. , vol.81 , pp. 5468-5472
    • Bernlohr, D.A.1    Angus, C.W.2    Lane, M.D.3    Bolanowski, M.A.4    Kelly Jr., T.J.5
  • 17
    • 0019784850 scopus 로고
    • F4/80, a monoclonal antibody directed specifically against the mouse macrophage
    • Austyn, J.M., and Gordon, S. 1981. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11:805-815. (Pubitemid 12237981)
    • (1981) European Journal of Immunology , vol.11 , Issue.10 , pp. 805-815
    • Austyn, J.M.1    Gordon, S.2
  • 18
    • 1242308499 scopus 로고    scopus 로고
    • Comparison of gene expression profiles between white and brown adipose tissues of rat by microarray analysis
    • DOI 10.1016/j.bcp.2003.09.010
    • Unami, A., Shinohara, Y., Kajimoto, K., and Baba, Y. 2004. Comparison of gene expression profiles between white and brown adipose tissues of rat by microarray analysis. Biochem. Pharmacol. 67:555-564. (Pubitemid 38232895)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.3 , pp. 555-564
    • Unami, A.1    Shinohara, Y.2    Kajimoto, K.3    Baba, Y.4
  • 19
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • DOI 10.1016/S0092-8674(00)81410-5
    • Puigserver, P., et al. 1998. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 92:829-839. (Pubitemid 28155321)
    • (1998) Cell , vol.92 , Issue.6 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 20
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer, S.R. 2006. Transcriptional control of adipocyte formation. Cell Metab. 4:263-273.
    • (2006) Cell Metab. , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 21
    • 4043164343 scopus 로고    scopus 로고
    • Effect of a C/EBP gene replacement on mitochondrial biogenesis in fat cells
    • Chiu, C.H., Lin, W.D., Huang, S.Y., and Lee, Y.H. 2004. Effect of a C/EBP gene replacement on mitochondrial biogenesis in fat cells. Genes Dev. 18:1970-1975.
    • (2004) Genes Dev. , vol.18 , pp. 1970-1975
    • Chiu, C.H.1    Lin, W.D.2    Huang, S.Y.3    Lee, Y.H.4
  • 22
    • 53549134683 scopus 로고    scopus 로고
    • Identification of white adipocyte progenitor cells in vivo
    • Rodeheffer, M.S., Birsoy, K., and Friedman, J.M. 2008. Identification of white adipocyte progenitor cells in vivo. Cell. 135:240-249.
    • (2008) Cell , vol.135 , pp. 240-249
    • Rodeheffer, M.S.1    Birsoy, K.2    Friedman, J.M.3
  • 24
    • 0037326196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α): Transcriptional coactivator and metabolic regulator
    • DOI 10.1210/er.2002-0012
    • Puigserver, P., and Spiegelman, B.M. 2003. Peroxisome proliferator-activated receptor-γ coactivator 1 α (PGC-1 α): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24:78-90. (Pubitemid 36223280)
    • (2003) Endocrine Reviews , vol.24 , Issue.1 , pp. 78-90
    • Puigserver, P.1    Spiegelman, B.M.2
  • 25
    • 0022499231 scopus 로고
    • Brown adipose tissue uncoupling protein content in human infants, children and adults
    • Lean, M.E., James, W.P., Jennings, G., and Trayhurn, P. 1986. Brown adipose tissue uncoupling protein content in human infants, children and adults. Clin. Sci. (Lond.). 71:291-297. (Pubitemid 16058739)
    • (1986) Clinical Science , vol.73 , Issue.3 , pp. 291-297
    • Lean, M.E.J.1    James, W.P.T.2    Jennings, G.3    Trayhurn, P.4
  • 27
    • 50949108719 scopus 로고    scopus 로고
    • Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
    • Murano, I., et al. 2008. Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice. J. Lipid Res. 49:1562-1568.
    • (2008) J. Lipid Res. , vol.49 , pp. 1562-1568
    • Murano, I.1
  • 28
    • 41949125675 scopus 로고    scopus 로고
    • Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus
    • Wang, Y., et al. 2008. Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus. J. Biol. Chem. 283:4766-4777.
    • (2008) J. Biol. Chem. , vol.283 , pp. 4766-4777
    • Wang, Y.1
  • 29
    • 17944377509 scopus 로고    scopus 로고
    • FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
    • DOI 10.1016/S0092-8674(01)00474-3
    • Cederberg, A., et al. 2001. FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell. 106:563-573. (Pubitemid 32879318)
    • (2001) Cell , vol.106 , Issue.5 , pp. 563-573
    • Cederberg, A.1    Gronning, L.M.2    Ahren, B.3    Tasken, K.4    Carlsson, P.5    Enerback, S.6
  • 32
    • 0034181368 scopus 로고    scopus 로고
    • Rapamycin inhibits human adipocyte differentiation in primary culture
    • Bell, A., Grunder, L., and Sorisky, A. 2000. Rapamycin inhibits human adipocyte differentiation in primary culture. Obes. Res. 8:249-254.
    • (2000) Obes. Res. , vol.8 , pp. 249-254
    • Bell, A.1    Grunder, L.2    Sorisky, A.3
  • 33
    • 0028885873 scopus 로고
    • Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells
    • Yeh, W.C., Bierer, B.E., and McKnight, S.L. 1995. Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. Proc. Natl. Acad. Sci. U. S. A. 92:11086-11090.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 11086-11090
    • Yeh, W.C.1    Bierer, B.E.2    McKnight, S.L.3
  • 34
    • 54849431380 scopus 로고    scopus 로고
    • Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration
    • Polak, P., et al. 2008. Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. Cell Metab. 8:399-410.
    • (2008) Cell Metab. , vol.8 , pp. 399-410
    • Polak, P.1
  • 35
    • 65949095803 scopus 로고    scopus 로고
    • Autophagy regulates lipid metabolism
    • Singh, R., et al. 2009. Autophagy regulates lipid metabolism. Nature. 458:1131-1135.
    • (2009) Nature , vol.458 , pp. 1131-1135
    • Singh, R.1
  • 37
    • 33644813043 scopus 로고    scopus 로고
    • JNK1 but not JNK2 promotes the development of steatohepatitis in mice
    • Schattenberg, J.M., et al. 2006. JNK1 but not JNK2 promotes the development of steatohepatitis in mice. Hepatology. 43:163-172.
    • (2006) Hepatology , vol.43 , pp. 163-172
    • Schattenberg, J.M.1
  • 41
    • 0025374590 scopus 로고
    • Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells
    • D'Ambra, R., Surana, M., Efrat, S., Starr, R.G., and Fleischer, N. 1990. Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells. Endocrinology. 126:2815-2822. (Pubitemid 20216530)
    • (1990) Endocrinology , vol.126 , Issue.6 , pp. 2815-2822
    • D'Ambra, R.1    Surana, M.2    Efrat, S.3    Starr, R.G.4    Fleischer, N.5
  • 42
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • DOI 10.1007/BF00280883
    • Matthews, D.R., et al. 1985. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 28:412-419. (Pubitemid 15018832)
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 43
    • 3843142885 scopus 로고    scopus 로고
    • Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1
    • DOI 10.1074/jbc.M404170200
    • Wang, Y., Schattenberg, J.M., Rigoli, R.M., Storz, P., and Czaja, M.J. 2004. Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1. J. Biol. Chem. 279:31089-31097. (Pubitemid 39037770)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.30 , pp. 31089-31097
    • Wang, Y.1    Schattenberg, J.M.2    Rigoli, R.M.3    Storz, P.4    Czaja, M.J.5
  • 44
    • 0015416350 scopus 로고
    • Effects of exercise on activity of heart and muscle mitochondria
    • Dohm, G.L., Huston, R.L., Askew, E.W., and Weiser, P.C. 1972. Effects of exercise on activity of heart and muscle mitochondria. Am. J. Physiol. 223:783-787.
    • (1972) Am. J. Physiol. , vol.223 , pp. 783-787
    • Dohm, G.L.1    Huston, R.L.2    Askew, E.W.3    Weiser, P.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.