-
1
-
-
0029938661
-
The role of proteinuria in the progression of chronic renal failure
-
Burton C., Harris K. P. G., The role of proteinuria in the progression of chronic renal failure. American Journal of Kidney Diseases 1996 27 6 765 775 2-s2.0-0029938661 (Pubitemid 26169027)
-
(1996)
American Journal of Kidney Diseases
, vol.27
, Issue.6
, pp. 765-775
-
-
Burton, C.1
Harris, K.P.G.2
-
2
-
-
33750736645
-
How does proteinuria cause progressive renal damage?
-
DOI 10.1681/ASN.2006040377
-
Abbate M., Zoja C., Remuzzi G., How does proteinuria cause progressive renal damage? Journal of the American Society of Nephrology 2006 17 11 2974 2984 2-s2.0-33750736645 10.1681/ASN.2006040377 (Pubitemid 44707757)
-
(2006)
Journal of the American Society of Nephrology
, vol.17
, Issue.11
, pp. 2974-2984
-
-
Abbate, M.1
Zoja, C.2
Remuzzi, G.3
-
3
-
-
0026769228
-
Tubulointerstitial changes as a major determinant in the progression of renal damage
-
2-s2.0-0026769228
-
Nath K. A., Tubulointerstitial changes as a major determinant in the progression of renal damage. American Journal of Kidney Diseases 1992 20 1 1 17 2-s2.0-0026769228
-
(1992)
American Journal of Kidney Diseases
, vol.20
, Issue.1
, pp. 1-17
-
-
Nath, K.A.1
-
4
-
-
0028838569
-
Blood pressure control, proteinuria, and the progression of renal disease: The modification of diet in renal disease study
-
2-s2.0-0028838569
-
Peterson J. C., Adler S., Burkart J. M., Greene T., Hebert L. A., Hunsicker L. G., King A. J., Klahr S., Massry S. G., Seifter J. L., Blood pressure control, proteinuria, and the progression of renal disease: the modification of diet in renal disease study. Annals of Internal Medicine 1995 123 10 754 762 2-s2.0-0028838569
-
(1995)
Annals of Internal Medicine
, vol.123
, Issue.10
, pp. 754-762
-
-
Peterson, J.C.1
Adler, S.2
Burkart, J.M.3
Greene, T.4
Hebert, L.A.5
Hunsicker, L.G.6
King, A.J.7
Klahr, S.8
Massry, S.G.9
Seifter, J.L.10
-
5
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
2-s2.0-0035922441 10.1056/NEJMoa011161
-
Brenner B. M., Cooper M. E., De Zeeuw D., Keane W. F., Mitch W. E., Parving H.-H., Remuzzi G., Snapinn S. M., Zhang Z., Shahinfar S., Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. The New England Journal of Medicine 2001 345 12 861 869 2-s2.0-0035922441 10.1056/NEJMoa011161
-
(2001)
The New England Journal of Medicine
, vol.345
, Issue.12
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
De Zeeuw, D.3
Keane, W.F.4
Mitch, W.E.5
Parving, H.-H.6
Remuzzi, G.7
Snapinn, S.M.8
Zhang, Z.9
Shahinfar, S.10
-
6
-
-
80052303130
-
Autophagy and aging
-
2-s2.0-80052303130 10.1016/j.cell.2011.07.030
-
Rubinsztein D. C., Mariño G., Kroemer G., Autophagy and aging. Cell 2011 146 5 682 695 2-s2.0-80052303130 10.1016/j.cell.2011.07.030
-
(2011)
Cell
, vol.146
, Issue.5
, pp. 682-695
-
-
Rubinsztein, D.C.1
Mariño, G.2
Kroemer, G.3
-
7
-
-
78650848689
-
The emerging role of autophagy in the pathophysiology of diabetes mellitus
-
2-s2.0-78650848689 10.4161/auto.7.1.13044
-
Gonzalez C. D., Lee M.-S., Marchetti P., Pietropaolo M., Towns R., Vaccaro M. I., Watada H., Wiley J. W., The emerging role of autophagy in the pathophysiology of diabetes mellitus. Autophagy 2011 7 1 2 11 2-s2.0-78650848689 10.4161/auto.7.1.13044
-
(2011)
Autophagy
, vol.7
, Issue.1
, pp. 2-11
-
-
Gonzalez, C.D.1
Lee, M.-S.2
Marchetti, P.3
Pietropaolo, M.4
Towns, R.5
Vaccaro, M.I.6
Watada, H.7
Wiley, J.W.8
-
8
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
DOI 10.1038/nature06639, PII NATURE06639
-
Mizushima N., Levine B., Cuervo A. M., Klionsky D. J., Autophagy fights disease through cellular self-digestion. Nature 2008 451 7182 1069 1075 2-s2.0-39849109338 10.1038/nature06639 (Pubitemid 351317450)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
9
-
-
77951169411
-
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
-
2-s2.0-77951169411 10.1172/JCI39492
-
Hartleben B., Gödel M., Meyer-Schwesinger C., Liu S., Ulrich T., Köbler S., Wiech T., Grahammer F., Arnold S. J., Lindenmeyer M. T., Cohen C. D., Pavenstädt H., Kerjaschki D., Mizushima N., Shaw A. S., Walz G., Huber T. B., Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. Journal of Clinical Investigation 2010 120 4 1084 1096 2-s2.0-77951169411 10.1172/JCI39492
-
(2010)
Journal of Clinical Investigation
, vol.120
, Issue.4
, pp. 1084-1096
-
-
Hartleben, B.1
Gödel, M.2
Meyer-Schwesinger, C.3
Liu, S.4
Ulrich, T.5
Köbler, S.6
Wiech, T.7
Grahammer, F.8
Arnold, S.J.9
Lindenmeyer, M.T.10
Cohen, C.D.11
Pavenstädt, H.12
Kerjaschki, D.13
Mizushima, N.14
Shaw, A.S.15
Walz, G.16
Huber, T.B.17
-
10
-
-
77951157657
-
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
-
2-s2.0-77951157657 10.1172/JCI41376
-
Kume S., Uzu T., Horiike K., Chin-Kanasaki M., Isshiki K., Araki S.-I., Sugimoto T., Haneda M., Kashiwagi A., Koya D., Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney. Journal of Clinical Investigation 2010 120 4 1043 1055 2-s2.0-77951157657 10.1172/JCI41376
-
(2010)
Journal of Clinical Investigation
, vol.120
, Issue.4
, pp. 1043-1055
-
-
Kume, S.1
Uzu, T.2
Horiike, K.3
Chin-Kanasaki, M.4
Isshiki, K.5
Araki, S.-I.6
Sugimoto, T.7
Haneda, M.8
Kashiwagi, A.9
Koya, D.10
-
11
-
-
79955626606
-
Autophagy protects the proximal tubule from degeneration and acute ischemic injury
-
2-s2.0-79955626606 10.1681/ASN.2010070705
-
Kimura T., Takabatake Y., Takahashi A., Kaimori J.-Y., Matsui I., Namba T., Kitamura H., Niimura F., Matsusaka T., Soga T., Rakugi H., Isaka Y., Autophagy protects the proximal tubule from degeneration and acute ischemic injury. Journal of the American Society of Nephrology 2011 22 5 902 913 2-s2.0-79955626606 10.1681/ASN.2010070705
-
(2011)
Journal of the American Society of Nephrology
, vol.22
, Issue.5
, pp. 902-913
-
-
Kimura, T.1
Takabatake, Y.2
Takahashi, A.3
Kaimori, J.-Y.4
Matsui, I.5
Namba, T.6
Kitamura, H.7
Niimura, F.8
Matsusaka, T.9
Soga, T.10
Rakugi, H.11
Isaka, Y.12
-
12
-
-
77749264299
-
Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury
-
2-s2.0-77749264299 10.2353/ajpath.2010.090594
-
Jiang M., Liu K., Luo J., Dong Z., Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury. American Journal of Pathology 2010 176 3 1181 1192 2-s2.0-77749264299 10.2353/ajpath.2010.090594
-
(2010)
American Journal of Pathology
, vol.176
, Issue.3
, pp. 1181-1192
-
-
Jiang, M.1
Liu, K.2
Luo, J.3
Dong, Z.4
-
13
-
-
84855996286
-
Autophagy guards against cisplatin-induced acute kidney injury
-
2-s2.0-84855996286 10.1016/j.ajpath.2011.11.001
-
Takahashi A., Kimura T., Takabatake Y., Namba T., Kaimori J., Kitamura H., Matsui I., Niimura F., Matsusaka T., Fujita N., Yoshimori T., Isaka Y., Rakugi H., Autophagy guards against cisplatin-induced acute kidney injury. American Journal of Pathology 2012 180 2 517 525 2-s2.0-84855996286 10.1016/j.ajpath.2011.11.001
-
(2012)
American Journal of Pathology
, vol.180
, Issue.2
, pp. 517-525
-
-
Takahashi, A.1
Kimura, T.2
Takabatake, Y.3
Namba, T.4
Kaimori, J.5
Kitamura, H.6
Matsui, I.7
Niimura, F.8
Matsusaka, T.9
Fujita, N.10
Yoshimori, T.11
Isaka, Y.12
Rakugi, H.13
-
14
-
-
49749120592
-
Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
-
2-s2.0-49749120592 10.1038/ki.2008.214
-
Periyasamy-Thandavan S., Jiang M., Wei Q., Smith R., Yin X.-M., Dong Z., Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells. Kidney International 2008 74 5 631 640 2-s2.0-49749120592 10.1038/ki.2008.214
-
(2008)
Kidney International
, vol.74
, Issue.5
, pp. 631-640
-
-
Periyasamy-Thandavan, S.1
Jiang, M.2
Wei, Q.3
Smith, R.4
Yin, X.-M.5
Dong, Z.6
-
15
-
-
44949102384
-
Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells
-
2-s2.0-44949102384 10.1152/ajprenal.00590.2007
-
Yang C., Kaushal V., Shah S. V., Kaushal G. P., Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. American Journal of Physiology-Renal Physiology 2008 294 4 F777 F787 2-s2.0-44949102384 10.1152/ajprenal.00590.2007
-
(2008)
American Journal of Physiology - Renal Physiology
, vol.294
, Issue.4
-
-
Yang, C.1
Kaushal, V.2
Shah, S.V.3
Kaushal, G.P.4
-
16
-
-
14044277429
-
The molecular machinery of autophagy: Unanswered questions
-
DOI 10.1242/jcs.01620
-
Klionsky D. J., The molecular machinery of autophagy: unanswered questions. Journal of Cell Science 2005 118 1 7 18 2-s2.0-14044277429 10.1242/jcs.01620 (Pubitemid 40277100)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.1
, pp. 7-18
-
-
Klionsky, D.J.1
-
17
-
-
33745023775
-
Chaperone-Mediated Autophagy in Aging and Disease
-
DOI 10.1016/S0070-2153(05)73007-6, PII S0070215305730076
-
Massey A. C., Zhang C., Cuervo A. M., Chaperone-mediated autophagy in aging and disease. Current Topics in Developmental Biology 2006 73 205 235 2-s2.0-33745023775 10.1016/S0070-2153(05)73007-6 (Pubitemid 43878134)
-
(2006)
Current Topics in Developmental Biology
, vol.73
, pp. 205-235
-
-
Massey, A.C.1
Zhang, C.2
Cuervo, A.M.3
-
18
-
-
77956414236
-
The origin of the autophagosomal membrane
-
2-s2.0-77956414236 10.1038/ncb0910-831
-
Tooze S. A., Yoshimori T., The origin of the autophagosomal membrane. Nature Cell Biology 2010 12 9 831 835 2-s2.0-77956414236 10.1038/ncb0910-831
-
(2010)
Nature Cell Biology
, vol.12
, Issue.9
, pp. 831-835
-
-
Tooze, S.A.1
Yoshimori, T.2
-
19
-
-
66449083078
-
ULK1 · ATG13 · FIP200 complex mediates mTOR signaling and is essential for autophagy
-
2-s2.0-66449083078 10.1074/jbc.M900573200
-
Ganley I. G., Lam D. H., Wang J., Ding X., Chen S., Jiang X., ULK1 · ATG13 · FIP200 complex mediates mTOR signaling and is essential for autophagy. The Journal of Biological Chemistry 2009 284 18 12297 12305 2-s2.0-66449083078 10.1074/jbc.M900573200
-
(2009)
The Journal of Biological Chemistry
, vol.284
, Issue.18
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam, D.H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
20
-
-
65249119430
-
Nutrient-dependent mTORCl association with the ULK1-Atg13-FIP200 complex required for autophagy
-
2-s2.0-65249119430 10.1091/mbc.E08-12-1248
-
Hosokawa N., Hara T., Kaizuka T., Kishi C., Takamura A., Miura Y., Iemura S.-I., Natsume T., Takehana K., Yamada N., Guan J.-L., Oshiro N., Mizushima N., Nutrient-dependent mTORCl association with the ULK1-Atg13-FIP200 complex required for autophagy. Molecular Biology of the Cell 2009 20 7 1981 1991 2-s2.0-65249119430 10.1091/mbc.E08-12-1248
-
(2009)
Molecular Biology of the Cell
, vol.20
, Issue.7
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
Kishi, C.4
Takamura, A.5
Miura, Y.6
Iemura, S.-I.7
Natsume, T.8
Takehana, K.9
Yamada, N.10
Guan, J.-L.11
Oshiro, N.12
Mizushima, N.13
-
21
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
2-s2.0-65249176304 10.1091/mbc.E08-12-1249
-
Jung C. H., Jun C. B., Ro S.-H., Kim Y.-M., Otto N. M., Cao J., Kundu M., Kim D.-H., ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Molecular Biology of the Cell 2009 20 7 1992 2003 2-s2.0-65249176304 10.1091/mbc.E08-12-1249
-
(2009)
Molecular Biology of the Cell
, vol.20
, Issue.7
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.-H.3
Kim, Y.-M.4
Otto, N.M.5
Cao, J.6
Kundu, M.7
Kim, D.-H.8
-
22
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang X. H., Jackson S., Seaman M., Brown K., Kempkes B., Hibshoosh H., Levine B., Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999 402 6762 672 676 2-s2.0-0000906170 10.1038/45257 (Pubitemid 129516338)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
23
-
-
38749136302
-
Regulation of macroautophagy by mTOR and Beclin 1 complexes
-
DOI 10.1016/j.biochi.2007.08.014, PII S0300908407002283
-
Pattingre S., Espert L., Biard-Piechaczyk M., Codogno P., Regulation of macroautophagy by mTOR and Beclin 1 complexes. Biochimie 2008 90 2 313 323 2-s2.0-38749136302 10.1016/j.biochi.2007.08.014 (Pubitemid 351181247)
-
(2008)
Biochimie
, vol.90
, Issue.2
, pp. 313-323
-
-
Pattingre, S.1
Espert, L.2
Biard-Piechaczyk, M.3
Codogno, P.4
-
24
-
-
67649467294
-
Dynamics and diversity in autophagy mechanisms: Lessons from yeast
-
2-s2.0-67649467294 10.1038/nrm2708
-
Nakatogawa H., Suzuki K., Kamada Y., Ohsumi Y., Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nature Reviews Molecular Cell Biology 2009 10 7 458 467 2-s2.0-67649467294 10.1038/nrm2708
-
(2009)
Nature Reviews Molecular Cell Biology
, vol.10
, Issue.7
, pp. 458-467
-
-
Nakatogawa, H.1
Suzuki, K.2
Kamada, Y.3
Ohsumi, Y.4
-
25
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
2-s2.0-78149475088 10.1152/physrev.00030.2009
-
Ravikumar B., Sarkar S., Davies J. E., Futter M., Garcia-Arencibia M., Green-Thompson Z. W., Jimenez-Sanchez M., Korolchuk V. I., Lichtenberg M., Luo S., Massey D. C. O., Menzies F. M., Moreau K., Narayanan U., Renna M., Siddiqi F. H., Underwood B. R., Winslow And A. R., Rubinsztein D. C., Regulation of mammalian autophagy in physiology and pathophysiology. Physiological Reviews 2010 90 4 1383 1435 2-s2.0-78149475088 10.1152/physrev.00030.2009
-
(2010)
Physiological Reviews
, vol.90
, Issue.4
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
Jimenez-Sanchez, M.7
Korolchuk, V.I.8
Lichtenberg, M.9
Luo, S.10
Massey, D.C.O.11
Menzies, F.M.12
Moreau, K.13
Narayanan, U.14
Renna, M.15
Siddiqi, F.H.16
Underwood, B.R.17
Winslow, A.R.18
Rubinsztein, D.C.19
-
26
-
-
75749122303
-
Methods in mammalian autophagy research
-
2-s2.0-75749122303 10.1016/j.cell.2010.01.028
-
Mizushima N., Yoshimori T., Levine B., Methods in mammalian autophagy research. Cell 2010 140 3 313 326 2-s2.0-75749122303 10.1016/j.cell.2010.01.028
-
(2010)
Cell
, vol.140
, Issue.3
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
27
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
2-s2.0-77956416339 10.1038/ncb0910-823
-
Mizushima N., Levine B., Autophagy in mammalian development and differentiation. Nature Cell Biology 2010 12 9 823 830 2-s2.0-77956416339 10.1038/ncb0910-823
-
(2010)
Nature Cell Biology
, vol.12
, Issue.9
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
28
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky D. J., Abeliovich H., Agostinis P., Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008 4 2 151 175 (Pubitemid 351231180)
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
Bamber, B.A.11
Bassham, D.C.12
Bergamini, E.13
Bi, X.14
Biard-Piechaczyk, M.15
Blum, J.S.16
Bredesen, D.E.17
Brodsky, J.L.18
Brumell, J.H.19
Brunk, U.T.20
Bursch, W.21
Camougrand, N.22
Cebollero, E.23
Cecconi, F.24
Chen, Y.25
Chin, L.-S.26
Choi, A.27
Chu, C.T.28
Chung, J.29
more..
-
29
-
-
36849089101
-
Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice
-
DOI 10.1016/j.cell.2007.10.035, PII S0092867407013542
-
Komatsu M., Waguri S., Koike M., Sou Y.-S., Ueno T., Hara T., Mizushima N., Iwata J.-I., Ezaki J., Murata S., Hamazaki J., Nishito Y., Iemura S.-I., Natsume T., Yanagawa T., Uwayama J., Warabi E., Yoshida H., Ishii T., Kobayashi A., Yamamoto M., Yue Z., Uchiyama Y., Kominami E., Tanaka K., Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007 131 6 1149 1163 2-s2.0-36849089101 10.1016/j.cell.2007.10.035 (Pubitemid 350235021)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.-s.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.-i.8
Ezaki, J.9
Murata, S.10
Hamazaki, J.11
Nishito, Y.12
Iemura, S.-i.13
Natsume, T.14
Yanagawa, T.15
Uwayama, J.16
Warabi, E.17
Yoshida, H.18
Ishii, T.19
Kobayashi, A.20
Yamamoto, M.21
Yue, Z.22
Uchiyama, Y.23
Kominami, E.24
Tanaka, K.25
more..
-
30
-
-
27944504351
-
Forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
DOI 10.1083/jcb.200507002
-
Bjørkøy G., Lamark T., Brech A., Outzen H., Perander M., Øvervatn A., Stenmark H., Johansen T., p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. Journal of Cell Biology 2005 171 4 603 614 2-s2.0-27944504351 10.1083/jcb.200507002 (Pubitemid 41668720)
-
(2005)
Journal of Cell Biology
, vol.171
, Issue.4
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
31
-
-
67650914230
-
AMPK in health and disease
-
2-s2.0-67650914230 10.1152/physrev.00011.2008
-
Steinberg G. R., Kemp B. E., AMPK in health and disease. Physiological Reviews 2009 89 3 1025 1078 2-s2.0-67650914230 10.1152/physrev.00011.2008
-
(2009)
Physiological Reviews
, vol.89
, Issue.3
, pp. 1025-1078
-
-
Steinberg, G.R.1
Kemp, B.E.2
-
32
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
2-s2.0-78650510609 10.1038/nrm3025
-
Zoncu R., Efeyan A., Sabatini D. M., MTOR: From growth signal integration to cancer, diabetes and ageing. Nature Reviews Molecular Cell Biology 2011 12 1 21 35 2-s2.0-78650510609 10.1038/nrm3025
-
(2011)
Nature Reviews Molecular Cell Biology
, vol.12
, Issue.1
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
33
-
-
32044465506
-
TOR signaling in growth and metabolism
-
DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
-
Wullschleger S., Loewith R., Hall M. N., TOR signaling in growth and metabolism. Cell 2006 124 3 471 484 2-s2.0-32044465506 10.1016/j.cell.2006.01. 016 (Pubitemid 43199434)
-
(2006)
Cell
, vol.124
, Issue.3
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
34
-
-
78649348967
-
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
-
2-s2.0-78649348967 10.1016/j.molcel.2010.09.026
-
Sengupta S., Peterson T. R., Sabatini D. M., Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Molecular Cell 2010 40 2 310 322 2-s2.0-78649348967 10.1016/j.molcel.2010.09.026
-
(2010)
Molecular Cell
, vol.40
, Issue.2
, pp. 310-322
-
-
Sengupta, S.1
Peterson, T.R.2
Sabatini, D.M.3
-
35
-
-
33745815985
-
AMP-activated protein kinase signaling in metabolic regulation
-
DOI 10.1172/JCI29044
-
Yun C. L., Zierath J. R., AMP-activated protein kinase signaling in metabolic regulation. Journal of Clinical Investigation 2006 116 7 1776 1783 2-s2.0-33745815985 10.1172/JCI29044 (Pubitemid 44033297)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1776-1783
-
-
Yun, C.L.1
Zierath, J.R.2
-
36
-
-
0024545981
-
Energy dependence of different steps in the autophagic lysosomal pathway
-
Plomp P. J. A. M., Gordon P. B., Meijer A. J., Hoyvik H., Seglen P. O., Energy dependence of different steps in the autophagic lysosomal pathway. The Journal of Biological Chemistry 1989 264 12 6699 6704 2-s2.0-0024545981 (Pubitemid 19114774)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.12
, pp. 6699-6704
-
-
Plomp, P.J.A.M.1
Gordon, P.B.2
Meijer, A.J.3
Hoyvik, H.4
Seglen, P.O.5
-
37
-
-
79551507263
-
AMPK-dependent phosphorylation of ULK1 induces autophagy
-
2-s2.0-79551507263 10.1016/j.cmet.2011.01.009
-
Zhao M., Klionsky D. J., AMPK-dependent phosphorylation of ULK1 induces autophagy. Cell Metabolism 2011 13 2 119 120 2-s2.0-79551507263 10.1016/j.cmet.2011.01.009
-
(2011)
Cell Metabolism
, vol.13
, Issue.2
, pp. 119-120
-
-
Zhao, M.1
Klionsky, D.J.2
-
38
-
-
0043127125
-
Rheb GTpase is a direct target of TSC2 GAP activity and regulates mTOR signaling
-
DOI 10.1101/gad.1110003
-
Inoki K., Li Y., Xu T., Guan K.-L., Rheb GTpase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes and Development 2003 17 15 1829 1834 2-s2.0-0043127125 10.1101/gad.1110003 (Pubitemid 36944560)
-
(2003)
Genes and Development
, vol.17
, Issue.15
, pp. 1829-1834
-
-
Inoki, K.1
Li, Y.2
Xu, T.3
Guan, K.-L.4
-
39
-
-
84859778293
-
MTOR signaling in growth control and disease
-
2-s2.0-84859778293 10.1016/j.cell.2012.03.017
-
Laplante M., Sabatini D. M., MTOR signaling in growth control and disease. Cell 2012 149 2 274 293 2-s2.0-84859778293 10.1016/j.cell.2012.03.017
-
(2012)
Cell
, vol.149
, Issue.2
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
40
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
DOI 10.1038/ncb839
-
Inoki K., Li Y., Zhu T., Wu J., Guan K.-L., TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nature Cell Biology 2002 4 9 648 657 2-s2.0-0036713778 10.1038/ncb839 (Pubitemid 34993700)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.-L.5
-
41
-
-
45849105156
-
The rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
DOI 10.1126/science.1157535
-
Sancak Y., Peterson T. R., Shaul Y. D., Lindquist R. A., Thoreen C. C., Bar-Peled L., Sabatini D. M., The rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 2008 320 5882 1496 1501 2-s2.0-45849105156 10.1126/science.1157535 (Pubitemid 351929429)
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
42
-
-
77951768486
-
Ragulator-rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
-
2-s2.0-77951768486 10.1016/j.cell.2010.02.024
-
Sancak Y., Bar-Peled L., Zoncu R., Markhard A. L., Nada S., Sabatini D. M., Ragulator-rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 2010 141 2 290 303 2-s2.0-77951768486 10.1016/j.cell.2010.02.024
-
(2010)
Cell
, vol.141
, Issue.2
, pp. 290-303
-
-
Sancak, Y.1
Bar-Peled, L.2
Zoncu, R.3
Markhard, A.L.4
Nada, S.5
Sabatini, D.M.6
-
43
-
-
57649221592
-
Hypoxic reactive oxygen species regulate the integrated stress response and cell survival
-
2-s2.0-57649221592 10.1074/jbc.M805056200
-
Liu L., Wise D. R., Diehl J. A., Simon M. C., Hypoxic reactive oxygen species regulate the integrated stress response and cell survival. The Journal of Biological Chemistry 2008 283 45 31153 31162 2-s2.0-57649221592 10.1074/jbc.M805056200
-
(2008)
The Journal of Biological Chemistry
, vol.283
, Issue.45
, pp. 31153-31162
-
-
Liu, L.1
Wise, D.R.2
Diehl, J.A.3
Simon, M.C.4
-
44
-
-
0042525938
-
NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
-
DOI 10.1093/emboj/cdg379
-
Sakon S., Xue X., Takekawa M., Sasazuki T., Okazaki T., Kojima Y., Piao J.-H., Yagita H., Okumura K., Doi T., Nakano H., NF- B inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. The EMBO Journal 2003 22 15 3898 3909 2-s2.0-0042525938 10.1093/emboj/cdg379 (Pubitemid 36975716)
-
(2003)
EMBO Journal
, vol.22
, Issue.15
, pp. 3898-3909
-
-
Sakon, S.1
Xue, X.2
Takekawa, M.3
Sasazuki, T.4
Okazaki, T.5
Kojima, Y.6
Piao, J.-H.7
Yagita, H.8
Okumura, K.9
Doi, T.10
Nakano, H.11
-
45
-
-
75649085703
-
Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP
-
2-s2.0-75649085703 10.1038/emboj.2009.321
-
Webber J. L., Tooze S. A., Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP. The EMBO journal 2010 29 1 27 40 2-s2.0-75649085703 10.1038/emboj.2009.321
-
(2010)
The EMBO Journal
, vol.29
, Issue.1
, pp. 27-40
-
-
Webber, J.L.1
Tooze, S.A.2
-
46
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
2-s2.0-75949098487 10.1073/pnas.0911187107
-
Vives-Bauza C., Zhou C., Huang Y., Cui M., De Vries R. L. A., Kim J., May J., Tocilescu M. A., Liu W., Ko H. S., Magrané J., Moore D. J., Dawson V. L., Grailhe R., Dawson T. M., Li C., Tieu K., Przedborski S., PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proceedings of the National Academy of Sciences of the United States of America 2010 107 1 378 383 2-s2.0-75949098487 10.1073/pnas.0911187107
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.1
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.A.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
Magrané, J.11
Moore, D.J.12
Dawson, V.L.13
Grailhe, R.14
Dawson, T.M.15
Li, C.16
Tieu, K.17
Przedborski, S.18
-
47
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
2-s2.0-75949130828 10.1038/ncb2012
-
Geisler S., Holmström K. M., Skujat D., Fiesel F. C., Rothfuss O. C., Kahle P. J., Springer W., PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nature Cell Biology 2010 12 2 119 131 2-s2.0-75949130828 10.1038/ncb2012
-
(2010)
Nature Cell Biology
, vol.12
, Issue.2
, pp. 119-131
-
-
Geisler, S.1
Holmström, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
48
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
2-s2.0-78649364332 10.1016/j.molcel.2010.09.022
-
Majmundar A. J., Wong W. J., Simon M. C., Hypoxia-inducible factors and the response to hypoxic stress. Molecular Cell 2010 40 2 294 309 2-s2.0-78649364332 10.1016/j.molcel.2010.09.022
-
(2010)
Molecular Cell
, vol.40
, Issue.2
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
49
-
-
77951228508
-
Hypoxia-induced autophagy: Cell death or cell survival?
-
2-s2.0-77951228508 10.1016/j.ceb.2009.11.015
-
Mazure N. M., Pouysségur J., Hypoxia-induced autophagy: cell death or cell survival? Current Opinion in Cell Biology 2010 22 2 177 180 2-s2.0-77951228508 10.1016/j.ceb.2009.11.015
-
(2010)
Current Opinion in Cell Biology
, vol.22
, Issue.2
, pp. 177-180
-
-
Mazure, N.M.1
Pouysségur, J.2
-
50
-
-
66349121718
-
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
-
2-s2.0-66349121718 10.1128/MCB.00166-09
-
Bellot G., Garcia-Medina R., Gounon P., Chiche J., Roux D., Pouysségur J., Mazure N. M., Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Molecular and Cellular Biology 2009 29 10 2570 2581 2-s2.0-66349121718 10.1128/MCB.00166-09
-
(2009)
Molecular and Cellular Biology
, vol.29
, Issue.10
, pp. 2570-2581
-
-
Bellot, G.1
Garcia-Medina, R.2
Gounon, P.3
Chiche, J.4
Roux, D.5
Pouysségur, J.6
Mazure, N.M.7
-
51
-
-
77956414236
-
The origin of the autophagosomal membrane
-
2-s2.0-77956414236 10.1038/ncb0910-831
-
Tooze S. A., Yoshimori T., The origin of the autophagosomal membrane. Nature Cell Biology 2010 12 9 831 835 2-s2.0-77956414236 10.1038/ncb0910-831
-
(2010)
Nature Cell Biology
, vol.12
, Issue.9
, pp. 831-835
-
-
Tooze, S.A.1
Yoshimori, T.2
-
52
-
-
78649357985
-
Protein quality control in the cytosol and the endoplasmic reticulum: Brothers in arms
-
2-s2.0-78649357985 10.1016/j.molcel.2010.10.001
-
Buchberger A., Bukau B., Sommer T., Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms. Molecular Cell 2010 40 2 238 252 2-s2.0-78649357985 10.1016/j.molcel.2010.10.001
-
(2010)
Molecular Cell
, vol.40
, Issue.2
, pp. 238-252
-
-
Buchberger, A.1
Bukau, B.2
Sommer, T.3
-
53
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
DOI 10.1128/MCB.01453-06
-
Ogata M., Hino S.-I., Saito A., Morikawa K., Kondo S., Kanemoto S., Murakami T., Taniguchi M., Tanii I., Yoshinaga K., Shiosaka S., Hammarback J. A., Urano F., Imaizumi K., Autophagy is activated for cell survival after endoplasmic reticulum stress. Molecular and Cellular Biology 2006 26 24 9220 9231 2-s2.0-33845459165 10.1128/MCB.01453-06 (Pubitemid 44904418)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.24
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.-I.2
Saito, A.3
Morikawa, K.4
Kondo, S.5
Kanemoto, S.6
Murakami, T.7
Taniguchi, M.8
Tanii, I.9
Yoshinaga, K.10
Shiosaka, S.11
Hammarback, J.A.12
Urano, F.13
Imaizumi, K.14
-
54
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
2-s2.0-74949118681 10.1172/JCI40027
-
Rouschop K. M. A., Van Den Beucken T., Dubois L., Niessen H., Bussink J., Savelkouls K., Keulers T., Mujcic H., Landuyt W., Voncken J. W., Lambin P., Van Der Kogel A. J., Koritzinsky M., Wouters B. G., The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. Journal of Clinical Investigation 2010 120 1 127 141 2-s2.0-74949118681 10.1172/JCI40027
-
(2010)
Journal of Clinical Investigation
, vol.120
, Issue.1
, pp. 127-141
-
-
Rouschop, K.M.A.1
Van Den Beucken, T.2
Dubois, L.3
Niessen, H.4
Bussink, J.5
Savelkouls, K.6
Keulers, T.7
Mujcic, H.8
Landuyt, W.9
Voncken, J.W.10
Lambin, P.11
Van Der Kogel, A.J.12
Koritzinsky, M.13
Wouters, B.G.14
-
55
-
-
38949151661
-
Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy
-
DOI 10.2174/157339908783502370
-
Ziyadeh F. N., Wolf G., Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy. Current Diabetes Reviews 2008 4 1 39 45 2-s2.0-38949151661 10.2174/157339908783502370 (Pubitemid 351210971)
-
(2008)
Current Diabetes Reviews
, vol.4
, Issue.1
, pp. 39-45
-
-
Ziyadeh, F.N.1
Wolf, G.2
-
56
-
-
45249108429
-
Proteinuria in diabetic kidney disease: A mechanistic viewpoint
-
DOI 10.1038/ki.2008.128, PII KI2008128
-
Jefferson J. A., Shankland S. J., Pichler R. H., Proteinuria in diabetic kidney disease: a mechanistic viewpoint. Kidney International 2008 74 1 22 36 2-s2.0-45249108429 10.1038/ki.2008.128 (Pubitemid 351841893)
-
(2008)
Kidney International
, vol.74
, Issue.1
, pp. 22-36
-
-
Jefferson, J.A.1
Shankland, S.J.2
Pichler, R.H.3
-
57
-
-
0031029379
-
Podocyte loss and progressive glomerular injury in type II diabetes
-
Pagtalunan M. E., Miller P. L., Jumping-Eagle S., Nelson R. G., Myers B. D., Rennke H. G., Coplon N. S., Sun L., Meyer T. W., Podocyte loss and progressive glomerular injury in type II diabetes. Journal of Clinical Investigation 1997 99 2 342 348 2-s2.0-0031029379 (Pubitemid 27053474)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.2
, pp. 342-348
-
-
Pagtalunan, M.E.1
Miller, P.L.2
Jumping-Eagle, S.3
Nelson, R.G.4
Myers, B.D.5
Rennke, H.G.6
Coplon, N.S.7
Sun, L.8
Meyer, T.W.9
-
58
-
-
0038718698
-
MAP-LC3, a promising autophagosomal marker, is processed during the differentiation and recovery of podocytes from PAN nephrosis
-
2-s2.0-0038718698
-
Asanuma K., Tanida I., Shirato I., Ueno T., Takahara H., Nishitani T., Kominami E., Tomino Y., MAP-LC3, a promising autophagosomal marker, is processed during the differentiation and recovery of podocytes from PAN nephrosis. The FASEB Journal 2003 17 9 1165 1167 2-s2.0-0038718698
-
(2003)
The FASEB Journal
, vol.17
, Issue.9
, pp. 1165-1167
-
-
Asanuma, K.1
Tanida, I.2
Shirato, I.3
Ueno, T.4
Takahara, H.5
Nishitani, T.6
Kominami, E.7
Tomino, Y.8
-
59
-
-
1542283812
-
In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker
-
DOI 10.1091/mbc.E03-09-0704
-
Mizushima N., Yamamoto A., Matsui M., Yoshimori T., Ohsumi Y., In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Molecular Biology of the Cell 2004 15 3 1101 1111 2-s2.0-1542283812 10.1091/mbc.E03-09-0704 (Pubitemid 38316219)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.3
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
60
-
-
33646113500
-
Two types of autophagy in the podocytes in renal biopsy specimens: Ultrastructural study
-
Sato S., Kitamura H., Adachi A., Sasaki Y., Ghazizadeh M., Two types of autophagy in the podocytes in renal biopsy specimens: ultrastructural study. Journal of Submicroscopic Cytology and Pathology 2006 38 2-3 167 174 2-s2.0-33646113500 (Pubitemid 47289379)
-
(2006)
Journal of Submicroscopic Cytology and Pathology
, vol.38
, Issue.2-3
, pp. 167-174
-
-
Sato, S.1
Kitamura, H.2
Adachi, A.3
Sasaki, Y.4
Ghazizadeh, M.5
-
61
-
-
84876117324
-
Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury
-
e60546
-
Fang L., Zhou Y., Cao H., Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS One 2013 8 4 e60546
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
Fang, L.1
Zhou, Y.2
Cao, H.3
-
62
-
-
84863230126
-
Inhibition of MTOR disrupts autophagic flux in podocytes
-
2-s2.0-84857952891 10.1681/ASN.2011070690
-
Cinà D. P., Onay T., Paltoo A., Li C., Maezawa Y., De Arteaga J., Jurisicova A., Quaggin S. E., Inhibition of MTOR disrupts autophagic flux in podocytes. Journal of the American Society of Nephrology 2012 23 3 412 420 2-s2.0-84857952891 10.1681/ASN.2011070690
-
(2012)
Journal of the American Society of Nephrology
, vol.23
, Issue.3
, pp. 412-420
-
-
Cinà, D.P.1
Onay, T.2
Paltoo, A.3
Li, C.4
Maezawa, Y.5
De Arteaga, J.6
Jurisicova, A.7
Quaggin, S.E.8
-
63
-
-
79957881425
-
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
-
2-s2.0-79957881425 10.1172/JCI44774
-
Gödel M., Hartleben B., Herbach N., Liu S., Zschiedrich S., Lu S., Debreczeni-Mór A., Lindenmeyer M. T., Rastaldi M.-P., Hartleben G., Wiech T., Fornoni A., Nelson R. G., Kretzler M., Wanke R., Pavenstädt H., Kerjaschki D., Cohen C. D., Hall M. N., Rüegg M. A., Inoki K., Walz G., Huber T. B., Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. Journal of Clinical Investigation 2011 121 6 2197 2209 2-s2.0-79957881425 10.1172/JCI44774
-
(2011)
Journal of Clinical Investigation
, vol.121
, Issue.6
, pp. 2197-2209
-
-
Gödel, M.1
Hartleben, B.2
Herbach, N.3
Liu, S.4
Zschiedrich, S.5
Lu, S.6
Debreczeni-Mór, A.7
Lindenmeyer, M.T.8
Rastaldi, M.-P.9
Hartleben, G.10
Wiech, T.11
Fornoni, A.12
Nelson, R.G.13
Kretzler, M.14
Wanke, R.15
Pavenstädt, H.16
Kerjaschki, D.17
Cohen, C.D.18
Hall, M.N.19
Rüegg, M.A.20
Inoki, K.21
Walz, G.22
Huber, T.B.23
more..
-
64
-
-
0032710966
-
Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria
-
DOI 10.1007/s001250051447
-
Meyer T. W., Bennett P. H., Nelson R. G., Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria. Diabetologia 1999 42 11 1341 1344 2-s2.0-0032710966 10.1007/s001250051447 (Pubitemid 29500971)
-
(1999)
Diabetologia
, vol.42
, Issue.11
, pp. 1341-1344
-
-
Meyer, T.W.1
Bennett, P.H.2
Nelson, R.G.3
-
65
-
-
79953834002
-
Implications of autophagy for glomerular aging and disease
-
2-s2.0-79953834002 10.1007/s00441-010-1115-0
-
Weide T., Huber T. B., Implications of autophagy for glomerular aging and disease. Cell and Tissue Research 2011 343 3 467 473 2-s2.0-79953834002 10.1007/s00441-010-1115-0
-
(2011)
Cell and Tissue Research
, vol.343
, Issue.3
, pp. 467-473
-
-
Weide, T.1
Huber, T.B.2
-
66
-
-
84859632390
-
Mammalian target of rapamycin signaling in the podocyte
-
2-s2.0-84859632390 10.1097/MNH.0b013e3283520f38
-
Inoki K., Huber T. B., Mammalian target of rapamycin signaling in the podocyte. Current Opinion in Nephrology and Hypertension 2012 21 3 251 257 2-s2.0-84859632390 10.1097/MNH.0b013e3283520f38
-
(2012)
Current Opinion in Nephrology and Hypertension
, vol.21
, Issue.3
, pp. 251-257
-
-
Inoki, K.1
Huber, T.B.2
-
67
-
-
34748880045
-
Rapamycin prevents early steps of the development of diabetic nephropathy in rats
-
DOI 10.1159/000106782
-
Yang Y., Wang J., Qin L., Shou Z., Zhao J., Wang H., Chen Y., Chen J., Rapamycin prevents early steps of the development of diabetic nephropathy in rats. American Journal of Nephrology 2007 27 5 495 502 2-s2.0-34748880045 10.1159/000106782 (Pubitemid 47482007)
-
(2007)
American Journal of Nephrology
, vol.27
, Issue.5
, pp. 495-502
-
-
Yang, Y.1
Wang, J.2
Qin, L.3
Shou, Z.4
Zhao, J.5
Wang, H.6
Chen, Y.7
Chen, J.8
-
68
-
-
43049095682
-
Adiponectin regulates albuminuria and podocyte function in mice
-
DOI 10.1172/JCI32691
-
Sharma K., RamachandraRao S., Qiu G., Usui H. K., Zhu Y., Dunn S. R., Ouedraogo R., Hough K., McCue P., Chan L., Falkner B., Goldstein B. J., Adiponectin regulates albuminuria and podocyte function in mice. Journal of Clinical Investigation 2008 118 5 1645 1656 2-s2.0-43049095682 10.1172/JCI32691 (Pubitemid 351632369)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.5
, pp. 1645-1656
-
-
Sharma, K.1
RamachandraRao, S.2
Qiu, G.3
Usui, H.K.4
Zhu, Y.5
Dunn, S.R.6
Ouedraogo, R.7
Hough, K.8
McCue, P.9
Chan, L.10
Falkner, B.11
Goldstein, B.J.12
-
69
-
-
0014421532
-
Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
-
2-s2.0-0014421532
-
Risdon R. A., Sloper J. C., De Wardener H. E., Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. The Lancet 1968 2 7564 363 366 2-s2.0-0014421532
-
(1968)
The Lancet
, vol.2
, Issue.7564
, pp. 363-366
-
-
Risdon, R.A.1
Sloper, J.C.2
De Wardener, H.E.3
-
70
-
-
84862635122
-
Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury
-
Liu S., Hartleben B., Kretz O., Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy 2012 8 5 826 837
-
(2012)
Autophagy
, vol.8
, Issue.5
, pp. 826-837
-
-
Liu, S.1
Hartleben, B.2
Kretz, O.3
-
71
-
-
84887070613
-
Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions
-
Yamahara K., Kume S., Koya D., Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions. Journal of the American Society of Nephrology 2013 24 11 1769 1781
-
(2013)
Journal of the American Society of Nephrology
, vol.24
, Issue.11
, pp. 1769-1781
-
-
Yamahara, K.1
Kume, S.2
Koya, D.3
-
72
-
-
81555225308
-
Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of sirt1 in diabetic wistar fatty (fa/fa) rats: A model of type 2 diabetes
-
2-s2.0-81555225308 10.1155/2011/908185 908185
-
Kitada M., Takeda A., Nagai T., Ito H., Kanasaki K., Koya D., Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of sirt1 in diabetic wistar fatty (fa/fa) rats: a model of type 2 diabetes. Experimental Diabetes Research 2011 2011 11 2-s2.0-81555225308 10.1155/2011/908185 908185
-
(2011)
Experimental Diabetes Research
, vol.2011
, pp. 11
-
-
Kitada, M.1
Takeda, A.2
Nagai, T.3
Ito, H.4
Kanasaki, K.5
Koya, D.6
-
73
-
-
70349616273
-
Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling
-
2-s2.0-70349616273 10.1371/journal.pone.0007124 e7124
-
Balgi A. D., Fonseca B. D., Donohue E., Tsang T. C. F., Lajoie P., Proud C. G., Nabi I. R., Roberge M., Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling. PLoS ONE 2009 4 9 2-s2.0-70349616273 10.1371/journal.pone.0007124 e7124
-
(2009)
PLoS ONE
, vol.4
, Issue.9
-
-
Balgi, A.D.1
Fonseca, B.D.2
Donohue, E.3
Tsang, T.C.F.4
Lajoie, P.5
Proud, C.G.6
Nabi, I.R.7
Roberge, M.8
-
74
-
-
35548996805
-
A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase
-
DOI 10.1038/sj.cdd.4402207, PII 4402207
-
Xu Z.-X., Liang J., Haridas V., Gaikwad A., Connolly F. P., Mills G. B., Gutterman J. U., A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase. Cell Death and Differentiation 2007 14 11 1948 1957 2-s2.0-35548996805 10.1038/sj.cdd.4402207 (Pubitemid 350011670)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.11
, pp. 1948-1957
-
-
Xu, Z.-X.1
Liang, J.2
Haridas, V.3
Gaikwad, A.4
Connolly, F.P.5
Mills, G.B.6
Gutterman, J.U.7
-
75
-
-
0028899789
-
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
-
2-s2.0-0028899789 10.1074/jbc.270.5.2320
-
Blommaart E. F. C., Luiken J. J. F. P., Blommaart P. J. E., Van Woerkom G. M., Meijer A. J., Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. The Journal of Biological Chemistry 1995 270 5 2320 2326 2-s2.0-0028899789 10.1074/jbc.270.5.2320
-
(1995)
The Journal of Biological Chemistry
, vol.270
, Issue.5
, pp. 2320-2326
-
-
Blommaart, E.F.C.1
Luiken, J.J.F.P.2
Blommaart, P.J.E.3
Van Woerkom, G.M.4
Meijer, A.J.5
-
76
-
-
72049105867
-
The role of the mammalian target of rapamycin (mTOR) in renal disease
-
2-s2.0-72049105867 10.1681/ASN.2008111186
-
Lieberthal W., Levine J. S., The role of the mammalian target of rapamycin (mTOR) in renal disease. Journal of the American Society of Nephrology 2009 20 12 2493 2502 2-s2.0-72049105867 10.1681/ASN.2008111186
-
(2009)
Journal of the American Society of Nephrology
, vol.20
, Issue.12
, pp. 2493-2502
-
-
Lieberthal, W.1
Levine, J.S.2
-
77
-
-
2442442944
-
Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies
-
DOI 10.1093/ndt/gfh079
-
Fervenza F. C., Fitzpatrick P. M., Mertz J., Erickson S. B., Liggett S., Popham S., Wochos D. N., Synhavsky A., Hippler S., Larson T. S., Bagniewski S. M., Velosa J. A., Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies. Nephrology Dialysis Transplantation 2004 19 5 1288 1292 2-s2.0-2442442944 10.1093/ndt/gfh079 (Pubitemid 38628153)
-
(2004)
Nephrology Dialysis Transplantation
, vol.19
, Issue.5
, pp. 1288-1292
-
-
Fervenza, F.C.1
Fitzpatrick, P.M.2
Mertz, J.3
Erickson, S.B.4
Liggett, S.5
Popham, S.6
Wochos, D.N.7
Synhavsky, A.8
Hippler, S.9
Larson, T.S.10
Bagniewski, S.M.11
Velosa, J.A.12
-
78
-
-
79951674629
-
MTOR and rapamycin in the kidney: Signaling and therapeutic implications beyond immunosuppression
-
2-s2.0-79951674629 10.1038/ki.2010.457
-
Huber T. B., Walz G., Kuehn E. W., MTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression. Kidney International 2011 79 5 502 511 2-s2.0-79951674629 10.1038/ki.2010.457
-
(2011)
Kidney International
, vol.79
, Issue.5
, pp. 502-511
-
-
Huber, T.B.1
Walz, G.2
Kuehn, E.W.3
-
79
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
2-s2.0-79551598347 10.1038/ncb2152
-
Kim J., Kundu M., Viollet B., Guan K.-L., AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nature Cell Biology 2011 13 2 132 141 2-s2.0-79551598347 10.1038/ncb2152
-
(2011)
Nature Cell Biology
, vol.13
, Issue.2
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.-L.4
-
80
-
-
0036791054
-
Metformin in patients with type 2 diabetes mellitus: Reconsideration of traditional contraindications
-
2-s2.0-0036791054 10.1016/S0953-6205(02)00131-0
-
Rachmani R., Slavachevski I., Levi Z., Zadok B.-S., Kedar Y., Ravid M., Metformin in patients with type 2 diabetes mellitus: reconsideration of traditional contraindications. European Journal of Internal Medicine 2002 13 7 428 433 2-s2.0-0036791054 10.1016/S0953-6205(02)00131-0
-
(2002)
European Journal of Internal Medicine
, vol.13
, Issue.7
, pp. 428-433
-
-
Rachmani, R.1
Slavachevski, I.2
Levi, Z.3
Zadok, B.-S.4
Kedar, Y.5
Ravid, M.6
-
81
-
-
77955566180
-
Lactic acidosis induced by metformin: Incidence, management and prevention
-
2-s2.0-77955566180 10.2165/11536790-000000000-00000
-
Lalau J.-D., Lactic acidosis induced by metformin: incidence, management and prevention. Drug Safety 2010 33 9 727 740 2-s2.0-77955566180 10.2165/11536790-000000000-00000
-
(2010)
Drug Safety
, vol.33
, Issue.9
, pp. 727-740
-
-
Lalau, J.-D.1
-
82
-
-
33846854690
-
A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy
-
DOI 10.1152/ajprenal.00278.2006
-
Lee M.-J., Feliers D., Mariappan M. M., Sataranatarajan K., Mahimainathan L., Musi N., Foretz M., Viollet B., Weinberg J. M., Choudhury G. G., Kasinath B. S., A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy. American Journal of Physiology-Renal Physiology 2007 292 2 F617 F627 2-s2.0-33846854690 10.1152/ajprenal.00278.2006 (Pubitemid 46220529)
-
(2007)
American Journal of Physiology - Renal Physiology
, vol.292
, Issue.2
-
-
Lee, M.-J.1
Feliers, D.2
Mariappan, M.M.3
Sataranatarajan, K.4
Mahimainathan, L.5
Musi, N.6
Foretz, M.7
Viollet, B.8
Weinberg, J.M.9
Choudhury, G.G.10
Kasinath, B.S.11
-
83
-
-
34247161367
-
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
-
DOI 10.1074/jbc.M609532200
-
Sarkar S., Davies J. E., Huang Z., Tunnacliffe A., Rubinsztein D. C., Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α -synuclein. The Journal of Biological Chemistry 2007 282 8 5641 5652 2-s2.0-34247161367 10.1074/jbc.M609532200 (Pubitemid 47093730)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.8
, pp. 5641-5652
-
-
Sarkar, S.1
Davies, J.E.2
Huang, Z.3
Tunnacliffe, A.4
Rubinsztein, D.C.5
-
84
-
-
25444483066
-
Lithium induces autophagy by inhibiting inositol monophosphatase
-
DOI 10.1083/jcb.200504035
-
Sarkar S., Floto R. A., Berger Z., Imarisio S., Cordenier A., Pasco M., Cook L. J., Rubinsztein D. C., Lithium induces autophagy by inhibiting inositol monophosphatase. Journal of Cell Biology 2005 170 7 1101 1111 2-s2.0-25444483066 10.1083/jcb.200504035 (Pubitemid 41362642)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.7
, pp. 1101-1111
-
-
Sarkar, S.1
Floto, R.A.2
Berger, Z.3
Imarisio, S.4
Cordenier, A.5
Pasco, M.6
Cook, L.J.7
Rubinsztein, D.C.8
-
85
-
-
42249106042
-
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
-
DOI 10.1038/nchembio.79, PII NCHEMBIO79
-
Williams A., Sarkar S., Cuddon P., Ttofi E. K., Saiki S., Siddiqi F. H., Jahreiss L., Fleming A., Pask D., Goldsmith P., O'Kane C. J., Floto R. A., Rubinsztein D. C., Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nature Chemical Biology 2008 4 5 295 305 2-s2.0-42249106042 10.1038/nchembio.79 (Pubitemid 351550888)
-
(2008)
Nature Chemical Biology
, vol.4
, Issue.5
, pp. 295-305
-
-
Williams, A.1
Sarkar, S.2
Cuddon, P.3
Ttofi, E.K.4
Saiki, S.5
Siddiqi, F.H.6
Jahreiss, L.7
Fleming, A.8
Pask, D.9
Goldsmith, P.10
O'Kane, C.J.11
Floto, R.A.12
Rubinsztein, D.C.13
-
86
-
-
36249011527
-
Bcl-xL augmentation potentially reduces ischemia/reperfusion induced proximal and distal tubular apoptosis and autophagy
-
DOI 10.1097/01.tp.0000287334.38933.e3, PII 0000789020071115000018
-
Chien C.-T., Shyue S.-K., Lai M.-K., Bcl-xL augmentation potentially reduces ischemia/reperfusion induced proximal and distal tubular apoptosis and autophagy. Transplantation 2007 84 9 1183 1190 2-s2.0-36249011527 10.1097/01.tp.0000287334.38933.e3 (Pubitemid 350125362)
-
(2007)
Transplantation
, vol.84
, Issue.9
, pp. 1183-1190
-
-
Chien, C.-T.1
Shyue, S.-K.2
Lai, M.-K.3
-
87
-
-
39149113436
-
Participation of autophagy in renal ischemia/reperfusion injury
-
2-s2.0-39149113436 10.1016/j.bbrc.2008.01.059
-
Suzuki C., Isaka Y., Takabatake Y., Tanaka H., Koike M., Shibata M., Uchiyama Y., Takahara S., Imai E., Participation of autophagy in renal ischemia/reperfusion injury. Biochemical and Biophysical Research Communications 2008 368 1 100 106 2-s2.0-39149113436 10.1016/j.bbrc.2008.01.059
-
(2008)
Biochemical and Biophysical Research Communications
, vol.368
, Issue.1
, pp. 100-106
-
-
Suzuki, C.1
Isaka, Y.2
Takabatake, Y.3
Tanaka, H.4
Koike, M.5
Shibata, M.6
Uchiyama, Y.7
Takahara, S.8
Imai, E.9
-
88
-
-
77952875466
-
Cisplatin-induced macroautophagy occurs prior to apoptosis in proximal tubules in vivo
-
2-s2.0-77952875466 10.1007/s10157-009-0254-7
-
Inoue K., Kuwana H., Shimamura Y., Ogata K., Taniguchi Y., Kagawa T., Horino T., Takao T., Morita T., Sasaki S., Mizushima N., Terada Y., Cisplatin-induced macroautophagy occurs prior to apoptosis in proximal tubules in vivo. Clinical and Experimental Nephrology 2010 14 2 112 122 2-s2.0-77952875466 10.1007/s10157-009-0254-7
-
(2010)
Clinical and Experimental Nephrology
, vol.14
, Issue.2
, pp. 112-122
-
-
Inoue, K.1
Kuwana, H.2
Shimamura, Y.3
Ogata, K.4
Taniguchi, Y.5
Kagawa, T.6
Horino, T.7
Takao, T.8
Morita, T.9
Sasaki, S.10
Mizushima, N.11
Terada, Y.12
-
89
-
-
52749093177
-
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
-
2-s2.0-52749093177 10.1016/j.cmet.2008.08.009
-
Ebato C., Uchida T., Arakawa M., Komatsu M., Ueno T., Komiya K., Azuma K., Hirose T., Tanaka K., Kominami E., Kawamori R., Fujitani Y., Watada H., Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. Cell Metabolism 2008 8 4 325 332 2-s2.0-52749093177 10.1016/j.cmet.2008.08.009
-
(2008)
Cell Metabolism
, vol.8
, Issue.4
, pp. 325-332
-
-
Ebato, C.1
Uchida, T.2
Arakawa, M.3
Komatsu, M.4
Ueno, T.5
Komiya, K.6
Azuma, K.7
Hirose, T.8
Tanaka, K.9
Kominami, E.10
Kawamori, R.11
Fujitani, Y.12
Watada, H.13
-
90
-
-
52749094770
-
Loss of autophagy diminishes pancreatic β cell mass and function with resultant hyperglycemia
-
2-s2.0-52749094770 10.1016/j.cmet.2008.08.013
-
Jung H. S., Chung K. W., Won Kim J., Kim J., Komatsu M., Tanaka K., Nguyen Y. H., Kang T. M., Yoon K.-H., Kim J.-W., Jeong Y. T., Han M. S., Lee M.-K., Kim K.-W., Shin J., Lee M.-S., Loss of autophagy diminishes pancreatic β cell mass and function with resultant hyperglycemia. Cell Metabolism 2008 8 4 318 324 2-s2.0-52749094770 10.1016/j.cmet.2008.08.013
-
(2008)
Cell Metabolism
, vol.8
, Issue.4
, pp. 318-324
-
-
Jung, H.S.1
Chung, K.W.2
Won Kim, J.3
Kim, J.4
Komatsu, M.5
Tanaka, K.6
Nguyen, Y.H.7
Kang, T.M.8
Yoon, K.-H.9
Kim, J.-W.10
Jeong, Y.T.11
Han, M.S.12
Lee, M.-K.13
Kim, K.-W.14
Shin, J.15
Lee, M.-S.16
-
91
-
-
78650822581
-
The double-edged effect of autophagy in pancreatic beta cells and diabetes
-
2-s2.0-78650822581 10.4161/auto.7.1.13607
-
Chen Z.-F., Li Y.-B., Han J.-Y., Wang J., Yin J.-J., Li J.-B., Tian H., The double-edged effect of autophagy in pancreatic beta cells and diabetes. Autophagy 2011 7 1 12 16 2-s2.0-78650822581 10.4161/auto.7.1.13607
-
(2011)
Autophagy
, vol.7
, Issue.1
, pp. 12-16
-
-
Chen, Z.-F.1
Li, Y.-B.2
Han, J.-Y.3
Wang, J.4
Yin, J.-J.5
Li, J.-B.6
Tian, H.7
-
92
-
-
70449448312
-
Autophagy regulates adipose mass and differentiation in mice
-
2-s2.0-70449448312 10.1172/JCI39228
-
Singh R., Xiang Y., Wang Y., Baikati K., Cuervo A. M., Luu Y. K., Tang Y., Pessin J. E., Schwartz G. J., Czaja M. J., Autophagy regulates adipose mass and differentiation in mice. Journal of Clinical Investigation 2009 119 11 3329 3339 2-s2.0-70449448312 10.1172/JCI39228
-
(2009)
Journal of Clinical Investigation
, vol.119
, Issue.11
, pp. 3329-3339
-
-
Singh, R.1
Xiang, Y.2
Wang, Y.3
Baikati, K.4
Cuervo, A.M.5
Luu, Y.K.6
Tang, Y.7
Pessin, J.E.8
Schwartz, G.J.9
Czaja, M.J.10
-
93
-
-
73949124173
-
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
-
2-s2.0-73949124173 10.1073/pnas.0906048106
-
Zhang Y., Goldman S., Baerga R., Zhao Y., Komatsu M., Jin S., Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proceedings of the National Academy of Sciences of the United States of America 2009 106 47 19860 19865 2-s2.0-73949124173 10.1073/pnas.0906048106
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.47
, pp. 19860-19865
-
-
Zhang, Y.1
Goldman, S.2
Baerga, R.3
Zhao, Y.4
Komatsu, M.5
Jin, S.6
-
94
-
-
51349095898
-
Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function
-
2-s2.0-51349095898 10.1038/nm.1851
-
Zhang C., Cuervo A. M., Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function. Nature Medicine 2008 14 9 959 965 2-s2.0-51349095898 10.1038/nm.1851
-
(2008)
Nature Medicine
, vol.14
, Issue.9
, pp. 959-965
-
-
Zhang, C.1
Cuervo, A.M.2
-
95
-
-
8344242220
-
Autophagy in health and disease: A double-edged sword
-
DOI 10.1126/science.1099993
-
Shintani T., Klionsky D. J., Autophagy in health and disease: a double-edged sword. Science 2004 306 5698 990 995 2-s2.0-8344242220 10.1126/science.1099993 (Pubitemid 39482894)
-
(2004)
Science
, vol.306
, Issue.5698
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
96
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
DOI 10.1038/nrc1692, PII N1692
-
Kondo Y., Kanzawa T., Sawaya R., Kondo S., The role of autophagy in cancer development and response to therapy. Nature Reviews Cancer 2005 5 9 726 734 2-s2.0-25444440875 10.1038/nrc1692 (Pubitemid 41486365)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.9
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
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