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Volumn 8, Issue 4, 2013, Pages

Epigenetic Regulation of BMP2 by 1,25-dihydroxyvitamin D3 through DNA Methylation and Histone Modification

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BONE MORPHOGENETIC PROTEIN 2; CALCITRIOL; HISTONE H3; TRICHOSTATIN A; VITAMIN D RECEPTOR;

EID: 84876434818     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061423     Document Type: Article
Times cited : (55)

References (52)
  • 1
    • 0013605262 scopus 로고
    • Metabolic and calcium kinetic studies in idiopathic hypercalciuria
    • Liberman UA, Sperling O, Atsmon A, Frank M, Modan M, et al. (1968) Metabolic and calcium kinetic studies in idiopathic hypercalciuria. J Clin Invest 47: 2580-2590.
    • (1968) J Clin Invest , vol.47 , pp. 2580-2590
    • Liberman, U.A.1    Sperling, O.2    Atsmon, A.3    Frank, M.4    Modan, M.5
  • 2
    • 0024207698 scopus 로고
    • Mechanism of hypercalciuria in genetic hypercalciuric rats. Inherited defect in intestinal calcium transport
    • Bushinsky DA, Favus MJ, (1988) Mechanism of hypercalciuria in genetic hypercalciuric rats. Inherited defect in intestinal calcium transport. J Clin Invest 82: 1585-1591.
    • (1988) J Clin Invest , vol.82 , pp. 1585-1591
    • Bushinsky, D.A.1    Favus, M.J.2
  • 3
    • 0030987182 scopus 로고    scopus 로고
    • Defective renal calcium reabsorption in genetic hypercalciuric rats
    • Tsuruoka S, Bushinsky DA, Schwartz GJ, (1997) Defective renal calcium reabsorption in genetic hypercalciuric rats. Kidney Int 51: 1540-1547.
    • (1997) Kidney Int , vol.51 , pp. 1540-1547
    • Tsuruoka, S.1    Bushinsky, D.A.2    Schwartz, G.J.3
  • 4
    • 0029761043 scopus 로고    scopus 로고
    • Genetic hypercalciuric stone forming rats
    • Bushinsky DA, (1996) Genetic hypercalciuric stone forming rats. Semin Nephrol 16: 448-457.
    • (1996) Semin Nephrol , vol.16 , pp. 448-457
    • Bushinsky, D.A.1
  • 5
    • 68949147936 scopus 로고    scopus 로고
    • Genetic hypercalciuric stone-forming rats have a primary decrease in BMD and strength
    • Grynpas M, Waldman S, Holmyard D, Bushinsky DA, (2009) Genetic hypercalciuric stone-forming rats have a primary decrease in BMD and strength. J Bone Miner Res 24: 1420-1426.
    • (2009) J Bone Miner Res , vol.24 , pp. 1420-1426
    • Grynpas, M.1    Waldman, S.2    Holmyard, D.3    Bushinsky, D.A.4
  • 6
    • 0027062929 scopus 로고
    • Reduced vertebral bone density in hypercalciuric nephrolithiasis
    • Pietschmann F, Breslau NA, Pak CY, (1992) Reduced vertebral bone density in hypercalciuric nephrolithiasis. J Bone Miner Res 7: 1383-1388.
    • (1992) J Bone Miner Res , vol.7 , pp. 1383-1388
    • Pietschmann, F.1    Breslau, N.A.2    Pak, C.Y.3
  • 7
    • 33749523054 scopus 로고    scopus 로고
    • Urine calcium excretion predicts bone loss in idiopathic hypercalciuria
    • Asplin JR, Donahue S, Kinder J, Coe FL, (2006) Urine calcium excretion predicts bone loss in idiopathic hypercalciuria. Kidney Int 70: 1463-1467.
    • (2006) Kidney Int , vol.70 , pp. 1463-1467
    • Asplin, J.R.1    Donahue, S.2    Kinder, J.3    Coe, F.L.4
  • 8
    • 0032523911 scopus 로고    scopus 로고
    • Hyperresponsiveness of vitamin D receptor gene expression to 1,25-dihydroxyvitamin D3. A new characteristic of genetic hypercalciuric stone-forming rats
    • Yao J, Kathpalia P, Bushinsky DA, Favus MJ, (1998) Hyperresponsiveness of vitamin D receptor gene expression to 1,25-dihydroxyvitamin D3. A new characteristic of genetic hypercalciuric stone-forming rats. J Clin Invest 101: 2223-2232.
    • (1998) J Clin Invest , vol.101 , pp. 2223-2232
    • Yao, J.1    Kathpalia, P.2    Bushinsky, D.A.3    Favus, M.J.4
  • 10
    • 33748084002 scopus 로고    scopus 로고
    • Vitamin D and calcium receptors: links to hypercalciuria
    • Bai S, Favus MJ, (2006) Vitamin D and calcium receptors: links to hypercalciuria. Curr Opin Nephrol Hypertens 15: 381-385.
    • (2006) Curr Opin Nephrol Hypertens , vol.15 , pp. 381-385
    • Bai, S.1    Favus, M.J.2
  • 11
    • 77953449738 scopus 로고    scopus 로고
    • Elevated vitamin D receptor levels in genetic hypercalciuric stone-forming rats are associated with downregulation of Snail
    • Bai S, Wang H, Shen J, Zhou R, Bushinsky DA, et al. (2010) Elevated vitamin D receptor levels in genetic hypercalciuric stone-forming rats are associated with downregulation of Snail. J Bone Miner Res 25: 830-840.
    • (2010) J Bone Miner Res , vol.25 , pp. 830-840
    • Bai, S.1    Wang, H.2    Shen, J.3    Zhou, R.4    Bushinsky, D.A.5
  • 12
    • 0029914457 scopus 로고    scopus 로고
    • Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow derived stromal cell lines, ST2 and MC3T3-G2/PA6
    • Yamaguchi A, Ishizuya T, Kintou N, Wada Y, Ketagiri T, et al. (1996) Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow derived stromal cell lines, ST2 and MC3T3-G2/PA6. Biochem Biophys Res Commun 220: 366-371.
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 366-371
    • Yamaguchi, A.1    Ishizuya, T.2    Kintou, N.3    Wada, Y.4    Ketagiri, T.5
  • 15
    • 0027050850 scopus 로고
    • Newly identified actions of the vitamin D endocrine system
    • Walters MR, (1992) Newly identified actions of the vitamin D endocrine system. Endocr Rev 13: 719-764.
    • (1992) Endocr Rev , vol.13 , pp. 719-764
    • Walters, M.R.1
  • 16
    • 0028988403 scopus 로고
    • Structure-function relationships in the vitamin D endocrine system
    • Bouillon R, Okamura WH, Norman AW, (1995) Structure-function relationships in the vitamin D endocrine system. Endocr Rev 16: 200-257.
    • (1995) Endocr Rev , vol.16 , pp. 200-257
    • Bouillon, R.1    Okamura, W.H.2    Norman, A.W.3
  • 17
    • 0023874134 scopus 로고
    • The vitamin D story: A collaborative effort of basic science and clinical medicine
    • DeLuca HF, (1988) The vitamin D story: A collaborative effort of basic science and clinical medicine. FASEB J 2: 224-236.
    • (1988) FASEB J , vol.2 , pp. 224-236
    • DeLuca, H.F.1
  • 18
    • 0030831553 scopus 로고    scopus 로고
    • Short-term treatment of rats with high dose 1,25-dihydroxyvitamin D3 stimulates bone formation and increases the number of osteoblast precursor cells in bone marrow
    • Erben RG, Scutt AM, Miao D, Kollenkirchen U, Haberey M, (1997) Short-term treatment of rats with high dose 1,25-dihydroxyvitamin D3 stimulates bone formation and increases the number of osteoblast precursor cells in bone marrow. Endocrinology 138: 4629-4635.
    • (1997) Endocrinology , vol.138 , pp. 4629-4635
    • Erben, R.G.1    Scutt, A.M.2    Miao, D.3    Kollenkirchen, U.4    Haberey, M.5
  • 19
    • 0031595068 scopus 로고    scopus 로고
    • Therapeutic efficacy of 1alpha,25-dihydroxyvitamin D3 and calcium in osteopenic ovariectomized rats: evidence for a direct anabolic effect of 1alpha,25-dihydroxyvitamin D3 on bone
    • Erben RG, Bromm S, Stangassinger M, (1998) Therapeutic efficacy of 1alpha,25-dihydroxyvitamin D3 and calcium in osteopenic ovariectomized rats: evidence for a direct anabolic effect of 1alpha,25-dihydroxyvitamin D3 on bone. Endocrinology 139: 4319-4328.
    • (1998) Endocrinology , vol.139 , pp. 4319-4328
    • Erben, R.G.1    Bromm, S.2    Stangassinger, M.3
  • 21
    • 3042590141 scopus 로고    scopus 로고
    • Direct action of 1,25-dihydroxyvitamin D on bone: VDRKO bone shows excessive bone formation in normal mineral condition
    • Tanaka H, Seino Y, (2004) Direct action of 1,25-dihydroxyvitamin D on bone: VDRKO bone shows excessive bone formation in normal mineral condition. J Steroid Biochem Mol Biol 89-90: 343-345.
    • (2004) J Steroid Biochem Mol Biol , vol.89-90 , pp. 343-345
    • Tanaka, H.1    Seino, Y.2
  • 22
    • 21644452584 scopus 로고    scopus 로고
    • Osteoblasts lacking the vitamin D receptor display enhanced osteogenic potential in vitro
    • Sooy K, Sabbagh Y, Demay MB, (2005) Osteoblasts lacking the vitamin D receptor display enhanced osteogenic potential in vitro. J Cell Biochem 94: 81-87.
    • (2005) J Cell Biochem , vol.94 , pp. 81-87
    • Sooy, K.1    Sabbagh, Y.2    Demay, M.B.3
  • 23
    • 0032963140 scopus 로고    scopus 로고
    • 1,25-(OH)2D3 down-regulates expression of Phex, a marker of the mature osteoblast
    • Ecarot B, Desbarats M, (1999) 1,25-(OH)2D3 down-regulates expression of Phex, a marker of the mature osteoblast. Endocrinology 140: 1192-1199.
    • (1999) Endocrinology , vol.140 , pp. 1192-1199
    • Ecarot, B.1    Desbarats, M.2
  • 24
    • 8744315936 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 down-regulation of PHEX gene expression is mediated by apparent repression of a 110 kDa transfactor that binds to a polyadenine element in the promoter
    • Hines ER, Kolek OI, Jones MD, Serey SH, Sirjani NB, et al. (2004) 1,25-dihydroxyvitamin D3 down-regulation of PHEX gene expression is mediated by apparent repression of a 110 kDa transfactor that binds to a polyadenine element in the promoter. J Biol Chem 279: 46406-46414.
    • (2004) J Biol Chem , vol.279 , pp. 46406-46414
    • Hines, E.R.1    Kolek, O.I.2    Jones, M.D.3    Serey, S.H.4    Sirjani, N.B.5
  • 25
    • 0036343579 scopus 로고    scopus 로고
    • 1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter
    • Drissi H, Pouliot A, Koolloos C, Stein JL, Lian JB, et al. (2002) 1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter. Exp Cell Res 274: 323-333.
    • (2002) Exp Cell Res , vol.274 , pp. 323-333
    • Drissi, H.1    Pouliot, A.2    Koolloos, C.3    Stein, J.L.4    Lian, J.B.5
  • 26
    • 84858256963 scopus 로고    scopus 로고
    • High dose 1,25(OH)2D3 inhibits osteoblast mineralization in vitro
    • Yamaguchi M, Weitzmann MN, (2012) High dose 1,25(OH)2D3 inhibits osteoblast mineralization in vitro. Int J Mol Med 29: 934-938.
    • (2012) Int J Mol Med , vol.29 , pp. 934-938
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 27
    • 0025672641 scopus 로고
    • Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone
    • Celeste AJ, Iannazi JA, Taylor RC, Hewick RM, Rosen V, et al. (1990) Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 87: 9843-9847.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9843-9847
    • Celeste, A.J.1    Iannazi, J.A.2    Taylor, R.C.3    Hewick, R.M.4    Rosen, V.5
  • 28
    • 0024256133 scopus 로고
    • Novel regulators of bone formation: Molecular clones and activities
    • Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, et al. (1988) Novel regulators of bone formation: Molecular clones and activities. Science 242: 1528-1534.
    • (1988) Science , vol.242 , pp. 1528-1534
    • Wozney, J.M.1    Rosen, V.2    Celeste, A.J.3    Mitsock, L.M.4    Whitters, M.J.5
  • 29
    • 0028341364 scopus 로고
    • Effects of transforming growth factor beta on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts
    • Harris SE, Bonewald LF, Harris MA, Sabatini M, Dallas S, et al. (1994) Effects of transforming growth factor beta on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts. J Bone Miner Res 9: 855-863.
    • (1994) J Bone Miner Res , vol.9 , pp. 855-863
    • Harris, S.E.1    Bonewald, L.F.2    Harris, M.A.3    Sabatini, M.4    Dallas, S.5
  • 31
    • 0029914457 scopus 로고    scopus 로고
    • Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow derived stromal cell lines, ST2 and MC3T3-G2/PA6
    • Yamaguchi A, Ishizuya T, Kintou N, Wada Y, Ketagiri T, et al. (1996) Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow derived stromal cell lines, ST2 and MC3T3-G2/PA6. Biochem Biophys Res Commun 220: 366-371.
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 366-371
    • Yamaguchi, A.1    Ishizuya, T.2    Kintou, N.3    Wada, Y.4    Ketagiri, T.5
  • 32
    • 0036133374 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells
    • Xiao G, Gopalakrishnan R, Jiang D, Reith E, Benson MD, et al. (2002) Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. J Bone Miner Res 17: 101-110.
    • (2002) J Bone Miner Res , vol.17 , pp. 101-110
    • Xiao, G.1    Gopalakrishnan, R.2    Jiang, D.3    Reith, E.4    Benson, M.D.5
  • 33
    • 0036181393 scopus 로고    scopus 로고
    • Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing
    • Cho TJ, Gerstenfeld LC, Einhorn TA, (2002) Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res 17: 513-520.
    • (2002) J Bone Miner Res , vol.17 , pp. 513-520
    • Cho, T.J.1    Gerstenfeld, L.C.2    Einhorn, T.A.3
  • 34
    • 33751506452 scopus 로고    scopus 로고
    • BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
    • Tsuji K, Bandyopadhyay A, Harfe BD, Cox K, Kakar S, et al. (2006) BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet 38: 1424-1429.
    • (2006) Nat Genet , vol.38 , pp. 1424-1429
    • Tsuji, K.1    Bandyopadhyay, A.2    Harfe, B.D.3    Cox, K.4    Kakar, S.5
  • 35
    • 59749100262 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells: isolation, expansion, characterization, viral transduction, and production of conditioned medium
    • Gnecchi M, Melo LG, (2009) Bone marrow-derived mesenchymal stem cells: isolation, expansion, characterization, viral transduction, and production of conditioned medium. Methods Mol Biol 482: 281-294.
    • (2009) Methods Mol Biol , vol.482 , pp. 281-294
    • Gnecchi, M.1    Melo, L.G.2
  • 36
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW, (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 37
    • 33847098311 scopus 로고    scopus 로고
    • Pdx-1 modulates histone H4 acetylation and insulin gene expression in terminally differentiated alpha-TC-1 cells
    • Wang HW, Breslin MB, Lan MS, (2007) Pdx-1 modulates histone H4 acetylation and insulin gene expression in terminally differentiated alpha-TC-1 cells. Pancreas 34: 248-253.
    • (2007) Pancreas , vol.34 , pp. 248-253
    • Wang, H.W.1    Breslin, M.B.2    Lan, M.S.3
  • 38
    • 0031665590 scopus 로고    scopus 로고
    • Bone density and skeletal metabolism are altered in idiopathic hypercalciuria
    • Giannini S, Nobile M, Sartori L, Calo L, Tasca A, et al. (1998) Bone density and skeletal metabolism are altered in idiopathic hypercalciuria. Clin Nephrol 50: 94-100.
    • (1998) Clin Nephrol , vol.50 , pp. 94-100
    • Giannini, S.1    Nobile, M.2    Sartori, L.3    Calo, L.4    Tasca, A.5
  • 39
    • 0036094023 scopus 로고    scopus 로고
    • Bone alterations in patients with idiopathic hypercalciuria and calcium nephrolithiasis
    • discussion 869
    • Tasca A, Cacciola A, Ferrarese P, Ioverno E, Visona E, et al. (2002) Bone alterations in patients with idiopathic hypercalciuria and calcium nephrolithiasis. Urology 59: 865-869; discussion 869.
    • (2002) Urology , vol.59 , pp. 865-869
    • Tasca, A.1    Cacciola, A.2    Ferrarese, P.3    Ioverno, E.4    Visona, E.5
  • 41
    • 33751537194 scopus 로고    scopus 로고
    • Minireview: vitamin D receptor: new assignments for an already busy receptor
    • Norman AW, (2006) Minireview: vitamin D receptor: new assignments for an already busy receptor. Endocrinology 147: 5542-5548.
    • (2006) Endocrinology , vol.147 , pp. 5542-5548
    • Norman, A.W.1
  • 42
    • 0035342666 scopus 로고    scopus 로고
    • Vitamin D receptor and nuclear receptor coactivators: Crucial interactions in vitamin D-mediated transcription
    • MacDonald PN, Baudino TA, Tokumaru H, Dowd DR, Zhang C, (2001) Vitamin D receptor and nuclear receptor coactivators: Crucial interactions in vitamin D-mediated transcription. Steroids 66: 171-176.
    • (2001) Steroids , vol.66 , pp. 171-176
    • MacDonald, P.N.1    Baudino, T.A.2    Tokumaru, H.3    Dowd, D.R.4    Zhang, C.5
  • 45
    • 31944432339 scopus 로고    scopus 로고
    • A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
    • Saxonov S, Berg P, Brutlag DL, (2006) A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc Natl Acad Sci USA 103: 1412-1417.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 1412-1417
    • Saxonov, S.1    Berg, P.2    Brutlag, D.L.3
  • 46
    • 35948981875 scopus 로고    scopus 로고
    • Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters
    • Shen L, Kondo Y, Guo Y, Zhang J, Zhang L, et al. (2007) Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet 3: 2023-2036.
    • (2007) PLoS Genet , vol.3 , pp. 2023-2036
    • Shen, L.1    Kondo, Y.2    Guo, Y.3    Zhang, J.4    Zhang, L.5
  • 47
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, et al. (2007) Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 39: 457-466.
    • (2007) Nat Genet , vol.39 , pp. 457-466
    • Weber, M.1    Hellmann, I.2    Stadler, M.B.3    Ramos, L.4    Paabo, S.5
  • 48
    • 51649129596 scopus 로고    scopus 로고
    • Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
    • Mohn F, Weber M, Rebhan M, Roloff TC, Richter J, et al. (2008) Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 30: 755-766.
    • (2008) Mol Cell , vol.30 , pp. 755-766
    • Mohn, F.1    Weber, M.2    Rebhan, M.3    Roloff, T.C.4    Richter, J.5
  • 49
    • 78751610660 scopus 로고    scopus 로고
    • Structure and function of histone H3 lysine 9 methyltransferases and demethylases
    • Krishnan S, Horowitz S, Trievel RC, (2011) Structure and function of histone H3 lysine 9 methyltransferases and demethylases. Chembiochem 12: 254-263.
    • (2011) Chembiochem , vol.12 , pp. 254-263
    • Krishnan, S.1    Horowitz, S.2    Trievel, R.C.3
  • 50
    • 11144354402 scopus 로고    scopus 로고
    • Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana
    • Jackson JP, Johnson L, Jasencakova Z, Zhang X, PerezBurgos L, et al. (2004) Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana. Chromosoma 112: 308-315.
    • (2004) Chromosoma , vol.112 , pp. 308-315
    • Jackson, J.P.1    Johnson, L.2    Jasencakova, Z.3    Zhang, X.4    PerezBurgos, L.5
  • 52
    • 0036211013 scopus 로고    scopus 로고
    • Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics
    • Eberharter A, Becker PB, (2002) Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics. EMBO Rep 3: 224-229.
    • (2002) EMBO Rep , vol.3 , pp. 224-229
    • Eberharter, A.1    Becker, P.B.2


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