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Volumn 13, Issue 1, 2013, Pages 20-35

Role of calcium, Vitamin D, and the extrarenal vitamin D hydroxylases in carcinogenesis

Author keywords

1 hydroxylase; 24 hydroxylase; 25 hydroxylase; Calcium; Calcium sensing receptor; Cancer; CaSR; Colorectal cancer; COX 2; CYP24A1; CYP27A1; CYP27B1; CYP2R1; Epigenetics; Methylation; Proliferation; Splice variants; Vitamin D; Wnt

Indexed keywords

15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; 25 HYDROXYLASE; 25 HYDROXYVITAMIN D; CALCIDIOL 1 MONOOXYGENASE; CALCITRIOL; CALCIUM; CHOLESTANETRIOL 26 MONOOXYGENASE; CYCLOOXYGENASE 2; MICRORNA; OXYGENASE; PROSTAGLANDIN E2; RETINOID X RECEPTOR; STEROID 24 HYDROXYLASE; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D RECEPTOR;

EID: 84878247928     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/187152013804487434     Document Type: Review
Times cited : (60)

References (237)
  • 1
    • 18844409137 scopus 로고    scopus 로고
    • The epidemiology of vitamin D and cancer incidence and mortality: A review (United States)
    • Giovannucci, E. The epidemiology of vitamin D and cancer incidence and mortality: a review (United States). Cancer Causes Control, 2005, 16 (2), 83-95.
    • (2005) Cancer Causes Control , vol.16 , Issue.2 , pp. 83-95
    • Giovannucci, E.1
  • 3
    • 0037302116 scopus 로고    scopus 로고
    • Intestinal calcium absorption: Molecular vitamin D mediated mechanisms
    • Bouillon, R.; Van Cromphaut, S.; Carmeliet, G. Intestinal calcium absorption: Molecular vitamin D mediated mechanisms. J. Cell. Biochem., 2003, 88 (2), 332-339.
    • (2003) J. Cell. Biochem , vol.88 , Issue.2 , pp. 332-339
    • Bouillon, R.1    van Cromphaut, S.2    Carmeliet, G.3
  • 4
    • 78650705554 scopus 로고    scopus 로고
    • Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors
    • Fleet, J. C.; Schoch, R. D. Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors. Crit. Rev. Clin. Lab. Sci., 47 (4), 181-195.
    • Crit. Rev. Clin. Lab. Sci , vol.47 , Issue.4 , pp. 181-195
    • Fleet, J.C.1    Schoch, R.D.2
  • 5
    • 7944227593 scopus 로고    scopus 로고
    • Vitamin D and the dual processes of intestinal calcium absorption
    • Wasserman, R. H. Vitamin D and the dual processes of intestinal calcium absorption. J. Nutr., 2004, 134 (11), 3137-3139.
    • (2004) J. Nutr , vol.134 , Issue.11 , pp. 3137-3139
    • Wasserman, R.H.1
  • 6
    • 0028902030 scopus 로고
    • Calcium transport in epithelial cells of the intestine and kidney
    • Kumar, R. Calcium transport in epithelial cells of the intestine and kidney. J. Cell. Biochem., 1995, 57 (3), 392-398.
    • (1995) J. Cell. Biochem , vol.57 , Issue.3 , pp. 392-398
    • Kumar, R.1
  • 8
    • 33846187147 scopus 로고    scopus 로고
    • Molecular regulation of calcium and bone metabolism through the vitamin D receptor
    • Fleet, J. C. Molecular regulation of calcium and bone metabolism through the vitamin D receptor. J. Musculoskelet. Neuronal. Interact., 2006, 6 (4), 336-337.
    • (2006) J. Musculoskelet. Neuronal. Interact , vol.6 , Issue.4 , pp. 336-337
    • Fleet, J.C.1
  • 9
    • 18244363907 scopus 로고    scopus 로고
    • The calcium-sensing receptor in normal physiology and pathophysiology: A review
    • Tfelt-Hansen, J.; Brown, E. M. The calcium-sensing receptor in normal physiology and pathophysiology: a review. Crit. Rev. Clin. Lab. Sci., 2005, 42 (1), 35-70.
    • (2005) Crit. Rev. Clin. Lab. Sci , vol.42 , Issue.1 , pp. 35-70
    • Tfelt-Hansen, J.1    Brown, E.M.2
  • 11
    • 18744411252 scopus 로고    scopus 로고
    • Vitamin D and calcium deficits predispose for multiple chronic diseases
    • Peterlik, M.; Cross, H. S. Vitamin D and calcium deficits predispose for multiple chronic diseases. Eur. J. Clin. Invest., 2005, 35 (5), 290-304.
    • (2005) Eur. J. Clin. Invest , vol.35 , Issue.5 , pp. 290-304
    • Peterlik, M.1    Cross, H.S.2
  • 12
    • 75049086111 scopus 로고    scopus 로고
    • Vitamin D and calcium insufficiencyrelated chronic diseases: Molecular and cellular pathophysiology
    • Peterlik, M.; Cross, H. S. Vitamin D and calcium insufficiencyrelated chronic diseases: molecular and cellular pathophysiology. Eur. J. Clin. Nutr., 2009, 63 (12), 1377-1386.
    • (2009) Eur. J. Clin. Nutr , vol.63 , Issue.12 , pp. 1377-1386
    • Peterlik, M.1    Cross, H.S.2
  • 13
    • 68549111008 scopus 로고    scopus 로고
    • Calcium, vitamin D and cancer
    • Peterlik, M.; Grant, W. B.; Cross, H. S. Calcium, vitamin D and cancer. Anticancer res., 2009, 29 (9), 3687-3698.
    • (2009) Anticancer Res , vol.29 , Issue.9 , pp. 3687-3698
    • Peterlik, M.1    Grant, W.B.2    Cross, H.S.3
  • 14
    • 0021910430 scopus 로고
    • Dietary vitamin D and calcium and risk of colorectal cancer: A 19-year prospective study in men
    • Garland, C.; Shekelle, R. B.; Barrett-Connor, E.; Criqui, M. H.; Rossof, A. H.; Paul, O. Dietary vitamin D and calcium and risk of colorectal cancer: a 19-year prospective study in men. Lancet, 1985, 1 (8424), 307-309.
    • (1985) Lancet , vol.1 , Issue.8424 , pp. 307-309
    • Garland, C.1    Shekelle, R.B.2    Barrett-Connor, E.3    Criqui, M.H.4    Rossof, A.H.5    Paul, O.6
  • 15
  • 17
    • 30744436834 scopus 로고    scopus 로고
    • Calcium plus vitamin D alters preneoplastic features of colorectal adenomas and rectal mucosa
    • Holt, P. R.; Bresalier, R. S.; Ma, C. K.; Liu, K. F.; Lipkin, M.; Byrd, J. C.; Yang, K. Calcium plus vitamin D alters preneoplastic features of colorectal adenomas and rectal mucosa. Cancer, 2006, 106 (2), 287-296.
    • (2006) Cancer , vol.106 , Issue.2 , pp. 287-296
    • Holt, P.R.1    Bresalier, R.S.2    Ma, C.K.3    Liu, K.F.4    Lipkin, M.5    Byrd, J.C.6    Yang, K.7
  • 18
    • 33646460311 scopus 로고    scopus 로고
    • Nutritional regulation of extrarenal vitamin D hydroxylase expression-potential application in tumor prevention and therapy
    • Cross, H. S.; Kallay, E. Nutritional regulation of extrarenal vitamin D hydroxylase expression-potential application in tumor prevention and therapy. Future Oncol., 2005, 1 (3), 415-424.
    • (2005) Future Oncol , vol.1 , Issue.3 , pp. 415-424
    • Cross, H.S.1    Kallay, E.2
  • 19
    • 34250015299 scopus 로고    scopus 로고
    • Vitamin D and calcium supplementation reduces cancer risk: Results of a randomized trial
    • Lappe, J. M.; Travers-Gustafson, D.; Davies, K. M.; Recker, R. R.; Heaney, R. P. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am. J. Clin. Nutr., 2007, 85 (6), 1586-1591.
    • (2007) Am. J. Clin. Nutr , vol.85 , Issue.6 , pp. 1586-1591
    • Lappe, J.M.1    Travers-Gustafson, D.2    Davies, K.M.3    Recker, R.R.4    Heaney, R.P.5
  • 20
    • 33644867212 scopus 로고    scopus 로고
    • Dietary and lifestyle determinants of mammographic breast density. A longitudinal study in a Mediterranean population
    • Masala, G.; Ambrogetti, D.; Assedi, M.; Giorgi, D.; Del Turco, M. R.; Palli, D. Dietary and lifestyle determinants of mammographic breast density. A longitudinal study in a Mediterranean population. Int. J. Cancer, 2006, 118 (7), 1782-1789.
    • (2006) Int. J. Cancer , vol.118 , Issue.7 , pp. 1782-1789
    • Masala, G.1    Ambrogetti, D.2    Assedi, M.3    Giorgi, D.4    Del Turco, M.R.5    Palli, D.6
  • 21
    • 80053196854 scopus 로고    scopus 로고
    • Calcium and vitamin D supplements and health outcomes: A reanalysis of the Women's Health Initiative (WHI) limited-access data set
    • Bolland, M. J.; Grey, A.; Gamble, G. D.; Reid, I. R. Calcium and vitamin D supplements and health outcomes: a reanalysis of the Women's Health Initiative (WHI) limited-access data set. Am.J. clin. Nutr., 2011, 94 (4), 1144-1149.
    • (2011) Am.J. Clin. Nutr , vol.94 , Issue.4 , pp. 1144-1149
    • Bolland, M.J.1    Grey, A.2    Gamble, G.D.3    Reid, I.R.4
  • 25
    • 46349096924 scopus 로고    scopus 로고
    • Dairy products, dietary calcium and vitamin D intake as risk factors for prostate cancer: A meta-analysis of 26,769 cases from 45 observational studies
    • Huncharek, M.; Muscat, J.; Kupelnick, B. Dairy products, dietary calcium and vitamin D intake as risk factors for prostate cancer: a meta-analysis of 26,769 cases from 45 observational studies. Nutr. Cancer, 2008, 60 (4), 421-441.
    • (2008) Nutr. Cancer , vol.60 , Issue.4 , pp. 421-441
    • Huncharek, M.1    Muscat, J.2    Kupelnick, B.3
  • 26
    • 33947498484 scopus 로고    scopus 로고
    • Calcium intake and vitamin D metabolism and action, in healthy conditions and in prostate cancer
    • Bonjour, J. P.; Chevalley, T.; Fardellone, P. Calcium intake and vitamin D metabolism and action, in healthy conditions and in prostate cancer. Br. J. Nutr., 2007, 97 (4), 611-616.
    • (2007) Br. J. Nutr , vol.97 , Issue.4 , pp. 611-616
    • Bonjour, J.P.1    Chevalley, T.2    Fardellone, P.3
  • 29
    • 83755195804 scopus 로고    scopus 로고
    • Vitamin D with or without calcium supplementation for prevention of cancer and fractures: An updated meta-analysis for the U.S. Preventive Services Task Force
    • Chung, M.; Lee, J.; Terasawa, T.; Lau, J.; Trikalinos, T. A. Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the U.S. Preventive Services Task Force. Ann. Intern. Med., 2011, 155 (12), 827-838.
    • (2011) Ann. Intern. Med , vol.155 , Issue.12 , pp. 827-838
    • Chung, M.1    Lee, J.2    Terasawa, T.3    Lau, J.4    Trikalinos, T.A.5
  • 30
    • 84858756455 scopus 로고    scopus 로고
    • Effect of Dietary Vitamin D and Calcium on the Growth of Androgen-insensitive Human Prostate Tumor in a Murine Model
    • Ray, R.; Banks, M.; Abuzahra, H.; Eddy, V. J.; Persons, K. S.; Lucia, M. S.; Lambert, J. R.; Holick, M. F. Effect of Dietary Vitamin D and Calcium on the Growth of Androgen-insensitive Human Prostate Tumor in a Murine Model. Anticancer res., 2012, 32 (3), 727-731.
    • (2012) Anticancer Res , vol.32 , Issue.3 , pp. 727-731
    • Ray, R.1    Banks, M.2    Abuzahra, H.3    Eddy, V.J.4    Persons, K.S.5    Lucia, M.S.6    Lambert, J.R.7    Holick, M.F.8
  • 31
    • 58949091455 scopus 로고    scopus 로고
    • Western-style diet-induced colonic tumors and their modulation by calcium and vitamin D in C57Bl/6 mice: A preclinical model for human sporadic colon cancer
    • Newmark, H. L.; Yang, K.; Kurihara, N.; Fan, K.; Augenlicht, L. H.; Lipkin, M. Western-style diet-induced colonic tumors and their modulation by calcium and vitamin D in C57Bl/6 mice: a preclinical model for human sporadic colon cancer. Carcinogenesis, 2009, 30 (1), 88-92.
    • (2009) Carcinogenesis , vol.30 , Issue.1 , pp. 88-92
    • Newmark, H.L.1    Yang, K.2    Kurihara, N.3    Fan, K.4    Augenlicht, L.H.5    Lipkin, M.6
  • 33
    • 46749132318 scopus 로고    scopus 로고
    • Effect of a Western-style diet fortified with increased calcium and vitamin D on mammary gland of C57BL/6 mice
    • Kurihara, N.; Fan, K.; Thaler, H. T.; Yang, K.; Lipkin, M. Effect of a Western-style diet fortified with increased calcium and vitamin D on mammary gland of C57BL/6 mice. J. Med. Food., 2008, 11 (2), 201-206.
    • (2008) J. Med. Food , vol.11 , Issue.2 , pp. 201-206
    • Kurihara, N.1    Fan, K.2    Thaler, H.T.3    Yang, K.4    Lipkin, M.5
  • 34
    • 0033585414 scopus 로고    scopus 로고
    • Influence of dietary calcium and vitamin D on diet-induced epithelial cell hyperproliferation in mice
    • Xue, L.; Lipkin, M.; Newmark, H.; Wang, J. Influence of dietary calcium and vitamin D on diet-induced epithelial cell hyperproliferation in mice. J. Natl. Cancer Inst., 1999, 91 (2), 176-181.
    • (1999) J. Natl. Cancer Inst , vol.91 , Issue.2 , pp. 176-181
    • Xue, L.1    Lipkin, M.2    Newmark, H.3    Wang, J.4
  • 35
    • 79952755589 scopus 로고    scopus 로고
    • Bioavailability and efficacy of vitamin D2 from UV-irradiated yeast in growing, vitamin D-deficient rats
    • Hohman, E. E.; Martin, B. R.; Lachcik, P. J.; Gordon, D. T.; Fleet, J. C.; Weaver, C. M. Bioavailability and efficacy of vitamin D2 from UV-irradiated yeast in growing, vitamin D-deficient rats. J. Agric. Food Chem., 2011, 59 (6), 2341-2346.
    • (2011) J. Agric. Food Chem , vol.59 , Issue.6 , pp. 2341-2346
    • Hohman, E.E.1    Martin, B.R.2    Lachcik, P.J.3    Gordon, D.T.4    Fleet, J.C.5    Weaver, C.M.6
  • 36
    • 84875591688 scopus 로고    scopus 로고
    • Vitamin D(2) from light-exposed edible mushrooms is safe, bioavailable and effectively supports bone growth in rats
    • Calvo, M. S.; Babu, U. S.; Garthoff, L. H.; Woods, T. O.; Dreher, M.; Hill, G.; Nagaraja, S. Vitamin D(2) from light-exposed edible mushrooms is safe, bioavailable and effectively supports bone growth in rats. Osteoporos. Int., 2012.
    • (2012) Osteoporos. Int.
    • Calvo, M.S.1    Babu, U.S.2    Garthoff, L.H.3    Woods, T.O.4    Dreher, M.5    Hill, G.6    Nagaraja, S.7
  • 37
    • 84884788411 scopus 로고    scopus 로고
    • D., Pike, W.J., Adams, J.S., Ed.; Elsevier
    • Jones, G.; Prosser, D. E. In: Vitamin D Feldman, D., Pike, W.J., Adams, J.S., Ed.; Elsevier, 2011; Vol. 1, pp. 23-42.
    • (2011) Vitamin D Feldman , vol.1 , pp. 23-42
    • Jones, G.1    Prosser, D.E.2
  • 38
    • 68549128631 scopus 로고    scopus 로고
    • Parallel elevation of colonic 1,25-dihydroxyvitamin D3 levels and apoptosis in female mice on a calcium-deficient diet
    • Nittke, T.; Kallay, E.; Manhardt, T.; Cross, H. S. Parallel elevation of colonic 1,25-dihydroxyvitamin D3 levels and apoptosis in female mice on a calcium-deficient diet. Anticancer Res., 2009, 29 (9), 3727-3732.
    • (2009) Anticancer Res , vol.29 , Issue.9 , pp. 3727-3732
    • Nittke, T.1    Kallay, E.2    Manhardt, T.3    Cross, H.S.4
  • 39
    • 84855989071 scopus 로고    scopus 로고
    • Determination of 1,25-dihydroxyvitamin D concentrations in human colon tissues and matched serum samples
    • Wagner, D.; Dias, A. G.; Schnabl, K.; Van der Kwast, T.; Vieth, R. Determination of 1,25-dihydroxyvitamin D concentrations in human colon tissues and matched serum samples. Anticancer Res., 2012, 32 (1), 259-263.
    • (2012) Anticancer Res , vol.32 , Issue.1 , pp. 259-263
    • Wagner, D.1    Dias, A.G.2    Schnabl, K.3    van der Kwast, T.4    Vieth, R.5
  • 40
    • 0014608571 scopus 로고
    • Activation of vitamin D by the liver
    • Ponchon, G.; Kennan, A. L.; DeLuca, H.F. Activation of vitamin D by the liver. J. Clin. Invest., 1969, 48 (11), 2032-2037.
    • (1969) J. Clin. Invest , vol.48 , Issue.11 , pp. 2032-2037
    • Ponchon, G.1    Kennan, A.L.2    Deluca, H.F.3
  • 41
    • 0014544345 scopus 로고
    • The role of the liver in the metabolism of vitamin D
    • Ponchon, G.; DeLuca, H. F. The role of the liver in the metabolism of vitamin D. J. Clin. Invest., 1969, 48 (7), 1273-1279.
    • (1969) J. Clin. Invest , vol.48 , Issue.7 , pp. 1273-1279
    • Ponchon, G.1    Deluca, H.F.2
  • 42
    • 2542433007 scopus 로고    scopus 로고
    • Identification of a novel rat microsomal vitamin D3 25-hydroxylase
    • Yamasaki, T.; Izumi, S.; Ide, H.; Ohyama, Y. Identification of a novel rat microsomal vitamin D3 25-hydroxylase. J. Biol. Chem., 2004, 279 (22), 22848-22856.
    • (2004) J. Biol. Chem , vol.279 , Issue.22 , pp. 22848-22856
    • Yamasaki, T.1    Izumi, S.2    Ide, H.3    Ohyama, Y.4
  • 43
    • 0037432633 scopus 로고    scopus 로고
    • 25-Hydroxylation of vitamin D3 in primary cultures of pig hepatocytes: Evidence for a role of both CYP2D25 and CYP27A1
    • Hosseinpour, F.; Ibranovic, I.; Tang, W.; Wikvall, K. 25-Hydroxylation of vitamin D3 in primary cultures of pig hepatocytes: evidence for a role of both CYP2D25 and CYP27A1. Biochem. Biophys. Res. Commun., 2003, 303 (3), 877-883.
    • (2003) Biochem. Biophys. Res. Commun , vol.303 , Issue.3 , pp. 877-883
    • Hosseinpour, F.1    Ibranovic, I.2    Tang, W.3    Wikvall, K.4
  • 44
    • 0025868097 scopus 로고
    • Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis
    • Cali, J. J.; Russell, D. W. Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. J. Biol. Chem., 1991, 266 (12), 7774-7778.
    • (1991) J. Biol. Chem , vol.266 , Issue.12 , pp. 7774-7778
    • Cali, J.J.1    Russell, D.W.2
  • 45
    • 0027305109 scopus 로고
    • Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positions
    • Guo, Y. D.; Strugnell, S.; Back, D. W.; Jones, G. Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positions. Proc. Natl. Acad. Sci. U. S. A., 1993, 90 (18), 8668-8672.
    • (1993) Proc. Natl. Acad. Sci. U. S. A , vol.90 , Issue.18 , pp. 8668-8672
    • Guo, Y.D.1    Strugnell, S.2    Back, D.W.3    Jones, G.4
  • 46
    • 0028982644 scopus 로고
    • 1 alpha,24(S)-dihydroxyvitamin D2: A biologically active product of 1 alpha-hydroxyvitamin D2 made in the human hepatoma, Hep3B
    • Strugnell, S.; Byford, V.; Makin, H. L.; Moriarty, R. M.; Gilardi, R.; LeVan, L. W.; Knutson, J. C.; Bishop, C. W.; Jones, G. 1 alpha,24(S)-dihydroxyvitamin D2: a biologically active product of 1 alpha-hydroxyvitamin D2 made in the human hepatoma, Hep3B. Biochem. J., 1995, 310 (Pt 1), 233-241.
    • (1995) Biochem. J , vol.310 , Issue.Pt 1 , pp. 233-241
    • Strugnell, S.1    Byford, V.2    Makin, H.L.3    Moriarty, R.M.4    Gilardi, R.5    Levan, L.W.6    Knutson, J.C.7    Bishop, C.W.8    Jones, G.9
  • 49
    • 0024394549 scopus 로고
    • Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
    • Andersson, S.; Davis, D. L.; Dahlback, H.; Jornvall, H.; Russell, D. W. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J. Biol. Chem., 1989, 264 (14), 8222-8229.
    • (1989) J. Biol. Chem , vol.264 , Issue.14 , pp. 8222-8229
    • Andersson, S.1    Davis, D.L.2    Dahlback, H.3    Jornvall, H.4    Russell, D.W.5
  • 50
    • 0026096610 scopus 로고
    • Multi-functional property of rat liver mitochondrial cytochrome P-450
    • Ohyama, Y.; Masumoto, O.; Usui, E.; Okuda, K. Multi-functional property of rat liver mitochondrial cytochrome P-450. J. Biochem., 1991, 109 (3), 389-393.
    • (1991) J. Biochem , vol.109 , Issue.3 , pp. 389-393
    • Ohyama, Y.1    Masumoto, O.2    Usui, E.3    Okuda, K.4
  • 51
    • 0032511035 scopus 로고    scopus 로고
    • Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene
    • Rosen, H.; Reshef, A.; Maeda, N.; Lippoldt, A.; Shpizen, S.; Triger, L.; Eggertsen, G.; Bjorkhem, I.; Leitersdorf, E. Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene. J. Biol. Chem., 1998, 273 (24), 14805-14812.
    • (1998) J. Biol. Chem , vol.273 , Issue.24 , pp. 14805-14812
    • Rosen, H.1    Reshef, A.2    Maeda, N.3    Lippoldt, A.4    Shpizen, S.5    Triger, L.6    Eggertsen, G.7    Bjorkhem, I.8    Leitersdorf, E.9
  • 52
    • 0034671509 scopus 로고    scopus 로고
    • Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding
    • Repa, J. J.; Lund, E. G.; Horton, J. D.; Leitersdorf, E.; Russell, D. W.; Dietschy, J. M.; Turley, S. D. Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding. J. Biol. Chem., 2000, 275 (50), 39685-39692.
    • (2000) J. Biol. Chem , vol.275 , Issue.50 , pp. 39685-39692
    • Repa, J.J.1    Lund, E.G.2    Horton, J.D.3    Leitersdorf, E.4    Russell, D.W.5    Dietschy, J.M.6    Turley, S.D.7
  • 53
    • 0141732321 scopus 로고    scopus 로고
    • Deorphanization of cytochrome P450 2R1: A microsomal vitamin D 25-hydroxilase
    • Cheng, J. B.; Motola, D. L.; Mangelsdorf, D. J.; Russell, D. W. Deorphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase. J Biol Chem, 2003, 278 (39), 38084-38093.
    • (2003) J Biol Chem , vol.278 , Issue.39 , pp. 38084-38093
    • Cheng, J.B.1    Motola, D.L.2    Mangelsdorf, D.J.3    Russell, D.W.4
  • 54
    • 78649447575 scopus 로고    scopus 로고
    • Cytochromes P450 are essential players in the vitamin D signaling system
    • Schuster, I. Cytochromes P450 are essential players in the vitamin D signaling system. Biochim. Biophys. Acta, 2011, 1814 (1), 186-199.
    • (2011) Biochim. Biophys. Acta , vol.1814 , Issue.1 , pp. 186-199
    • Schuster, I.1
  • 56
    • 80054725615 scopus 로고    scopus 로고
    • Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis
    • Simon, K. C.; Munger, K. L.; Kraft, P.; Hunter, D. J.; De Jager, P. L.; Ascherio, A. Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis. J. Neurol., 2011, 258 (9), 1676-1682.
    • (2011) J. Neurol , vol.258 , Issue.9 , pp. 1676-1682
    • Simon, K.C.1    Munger, K.L.2    Kraft, P.3    Hunter, D.J.4    de Jager, P.L.5    Ascherio, A.6
  • 57
    • 78049431943 scopus 로고    scopus 로고
    • Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects
    • Bu, F. X.; Armas, L.; Lappe, J.; Zhou, Y.; Gao, G.; Wang, H. W.; Recker, R.; Zhao, L. J. Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects. Hum. Genet., 2010, 128 (5), 549-556.
    • (2010) Hum. Genet , vol.128 , Issue.5 , pp. 549-556
    • Bu, F.X.1    Armas, L.2    Lappe, J.3    Zhou, Y.4    Gao, G.5    Wang, H.W.6    Recker, R.7    Zhao, L.J.8
  • 59
    • 36749050449 scopus 로고    scopus 로고
    • CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans
    • Ramos-Lopez, E.; Bruck, P.; Jansen, T.; Herwig, J.; Badenhoop, K. CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans. Diabetes Metab. Res. Rev., 2007, 23 (8), 631-636.
    • (2007) Diabetes Metab. Res. Rev , vol.23 , Issue.8 , pp. 631-636
    • Ramos-Lopez, E.1    Bruck, P.2    Jansen, T.3    Herwig, J.4    Badenhoop, K.5
  • 64
    • 15444379063 scopus 로고    scopus 로고
    • Characterization of recombinant CYP2C11: A vitamin D 25-hydroxylase and 24- hydroxylase
    • Rahmaniyan, M.; Patrick, K.; Bell, N. H. Characterization of recombinant CYP2C11: a vitamin D 25-hydroxylase and 24- hydroxylase. Am. J. Physiol. Endocrinol. Metab., 2005, 288 (4), E753-760.
    • (2005) Am. J. Physiol. Endocrinol. Metab , vol.288 , Issue.4
    • Rahmaniyan, M.1    Patrick, K.2    Bell, N.H.3
  • 65
    • 0023752569 scopus 로고
    • Purification and characterization of vitamin D 25-hydroxylase from rat liver mitochondria
    • Masumoto, O.; Ohyama, Y.; Okuda, K. Purification and characterization of vitamin D 25-hydroxylase from rat liver mitochondria. J. Biol. Chem., 1988, 263 (28), 14256-14260.
    • (1988) J. Biol. Chem , vol.263 , Issue.28 , pp. 14256-14260
    • Masumoto, O.1    Ohyama, Y.2    Okuda, K.3
  • 66
    • 0023423581 scopus 로고
    • Sex differences in the hydroxylation of cholecalciferol and of 5 beta-cholestane-3 alpha, 7 alpha, 12 alphatriol in rat liver
    • Saarem, K.; Pedersen, J. I. Sex differences in the hydroxylation of cholecalciferol and of 5 beta-cholestane-3 alpha, 7 alpha, 12 alphatriol in rat liver. Biochem. J., 1987, 247 (1), 73-78.
    • (1987) Biochem. J , vol.247 , Issue.1 , pp. 73-78
    • Saarem, K.1    Pedersen, J.I.2
  • 67
    • 45249121177 scopus 로고    scopus 로고
    • Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4
    • Zhou, S. F. Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4. Curr. Drug. Metab., 2008, 9 (4), 310-322.
    • (2008) Curr. Drug. Metab , vol.9 , Issue.4 , pp. 310-322
    • Zhou, S.F.1
  • 68
    • 14044271607 scopus 로고    scopus 로고
    • CYP3A4 is a vitamin D-24- and 25-hydroxylase: Analysis of structure function by site-directed mutagenesis
    • Gupta, R. P.; He, Y. A.; Patrick, K. S.; Halpert, J. R.; Bell, N. H. CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis. J. Clin. Endocrinol. Metab., 2005, 90 (2), 1210-1219.
    • (2005) J. Clin. Endocrinol. Metab , vol.90 , Issue.2 , pp. 1210-1219
    • Gupta, R.P.1    He, Y.A.2    Patrick, K.S.3    Halpert, J.R.4    Bell, N.H.5
  • 70
    • 27544509096 scopus 로고    scopus 로고
    • Biological actions of extra-renal 25- hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment
    • Townsend, K.; Evans, K. N.; Campbell, M. J.; Colston, K. W.; Adams, J. S.; Hewison, M. Biological actions of extra-renal 25- hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment. J. Steroid Biochem. Mol. Biol., 2005, 97 (1-2), 103-109.
    • (2005) J. Steroid Biochem. Mol. Biol , vol.97 , Issue.1-2 , pp. 103-109
    • Townsend, K.1    Evans, K.N.2    Campbell, M.J.3    Colston, K.W.4    Adams, J.S.5    Hewison, M.6
  • 73
    • 77950301126 scopus 로고    scopus 로고
    • Metabolism of substrates incorporated into phospholipid vesicles by mouse 25- hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1)
    • Tang, E. K.; Voo, K. J.; Nguyen, M. N.; Tuckey, R. C. Metabolism of substrates incorporated into phospholipid vesicles by mouse 25- hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1). J. Steroid Biochem. Mol. Biol., 2010, 119 (3-5), 171-179.
    • (2010) J. Steroid Biochem. Mol. Biol , vol.119 , Issue.3-5 , pp. 171-179
    • Tang, E.K.1    Voo, K.J.2    Nguyen, M.N.3    Tuckey, R.C.4
  • 74
    • 77953951034 scopus 로고    scopus 로고
    • Genetic disorders and defects in vitamin d action
    • table of contents
    • Malloy, P. J.; Feldman, D. Genetic disorders and defects in vitamin d action. Endocrinol. Metab. Clin. North. Am., 2010, 39 (2), 333-346, table of contents.
    • (2010) Endocrinol. Metab. Clin. North. Am , vol.39 , Issue.2 , pp. 333-346
    • Malloy, P.J.1    Feldman, D.2
  • 78
    • 78649447575 scopus 로고    scopus 로고
    • Cytochromes P450 are essential players in the vitamin D signaling system
    • Schuster, I. Cytochromes P450 are essential players in the vitamin D signaling system. Biochim. Biophys. Acta, 2011, 1814 (1), 186-199.
    • (2011) Biochim. Biophys. Acta , vol.1814 , Issue.1 , pp. 186-199
    • Schuster, I.1
  • 79
    • 8544284075 scopus 로고    scopus 로고
    • Enzymes involved in the activation and inactivation of vitamin D
    • Prosser, D. E.; Jones, G. Enzymes involved in the activation and inactivation of vitamin D. Trends Biochem. Sci., 2004, 29 (12), 664-673.
    • (2004) Trends Biochem. Sci , vol.29 , Issue.12 , pp. 664-673
    • Prosser, D.E.1    Jones, G.2
  • 80
    • 0001241446 scopus 로고    scopus 로고
    • Metabolic studies using recombinant escherichia coli cells producing rat mitochondrial CYP24 CYP24 can convert 1alpha,25- dihydroxyvitamin D3 to calcitroic acid
    • Sakaki, T.; Sawada, N.; Nonaka, Y.; Ohyama, Y.; Inouye, K. Metabolic studies using recombinant escherichia coli cells producing rat mitochondrial CYP24 CYP24 can convert 1alpha,25- dihydroxyvitamin D3 to calcitroic acid. Eur. J. Biochem., 1999, 262 (1), 43-48.
    • (1999) Eur. J. Biochem , vol.262 , Issue.1 , pp. 43-48
    • Sakaki, T.1    Sawada, N.2    Nonaka, Y.3    Ohyama, Y.4    Inouye, K.5
  • 81
    • 80051691314 scopus 로고    scopus 로고
    • Bioengineering anabolic vitamin D-25-hydroxylase activity into the human vitamin D catabolic enzyme, cytochrome P450 CYP24A1, by a V391L mutation
    • Kaufmann, M.; Prosser, D. E.; Jones, G. Bioengineering anabolic vitamin D-25-hydroxylase activity into the human vitamin D catabolic enzyme, cytochrome P450 CYP24A1, by a V391L mutation. J. Biol. Chem., 2011, 286 (33), 28729-28737.
    • (2011) J. Biol. Chem , vol.286 , Issue.33 , pp. 28729-28737
    • Kaufmann, M.1    Prosser, D.E.2    Jones, G.3
  • 82
    • 0028218006 scopus 로고
    • Increased renal 25- hydroxyvitamin D3-24-hydroxylase messenger ribonucleic acid and immunoreactive protein in phosphate-deprived Hyp mice: A mechanism for accelerated 1,25-dihydroxyvitamin D3 catabolism in X-linked hypophosphatemic rickets
    • Roy, S.; Martel, J.; Ma, S.; Tenenhouse, H. S. Increased renal 25- hydroxyvitamin D3-24-hydroxylase messenger ribonucleic acid and immunoreactive protein in phosphate-deprived Hyp mice: a mechanism for accelerated 1,25-dihydroxyvitamin D3 catabolism in X-linked hypophosphatemic rickets. Endocrinology, 1994, 134 (4), 1761-1767.
    • (1994) Endocrinology , vol.134 , Issue.4 , pp. 1761-1767
    • Roy, S.1    Martel, J.2    Ma, S.3    Tenenhouse, H.S.4
  • 86
    • 84863229578 scopus 로고    scopus 로고
    • Hypercalcemia, Hypercalciuria, and Elevated Calcitriol Concentrations with Autosomal Dominant Transmission Due to CYP24A1 Mutations: Effects of Ketoconazole Therapy
    • Tebben, P. J.; Milliner, D. S.; Horst, R. L.; Harris, P. C.; Singh, R. J.; Wu, Y.; Foreman, J. W.; Chelminski, P. R.; Kumar, R. Hypercalcemia, Hypercalciuria, and Elevated Calcitriol Concentrations with Autosomal Dominant Transmission Due to CYP24A1 Mutations: Effects of Ketoconazole Therapy. J. Clin. Endocrinol. Metab., 2012, 97 (3), E423-427.
    • (2012) J. Clin. Endocrinol. Metab , vol.97 , Issue.3
    • Tebben, P.J.1    Milliner, D.S.2    Horst, R.L.3    Harris, P.C.4    Singh, R.J.5    Wu, Y.6    Foreman, J.W.7    Chelminski, P.R.8    Kumar, R.9
  • 88
    • 66449083031 scopus 로고    scopus 로고
    • Vitamin D for cancer prevention: Global perspective
    • Garland, C. F.; Gorham, E. D.; Mohr, S. B.; Garland, F. C. Vitamin D for cancer prevention: global perspective. Ann. Epidemiol., 2009, 19 (7), 468-483.
    • (2009) Ann. Epidemiol , vol.19 , Issue.7 , pp. 468-483
    • Garland, C.F.1    Gorham, E.D.2    Mohr, S.B.3    Garland, F.C.4
  • 91
    • 77951127705 scopus 로고    scopus 로고
    • Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
    • Blomberg Jensen, M.; Andersen, C. B.; Nielsen, J. E.; Bagi, P.; Jorgensen, A.; Juul, A.; Leffers, H. Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer. J. Steroid Biochem. Mol. Biol., 2010, 121 (1-2), 376-382.
    • (2010) J. Steroid Biochem. Mol. Biol , vol.121 , Issue.1-2 , pp. 376-382
    • Blomberg, J.M.1    Andersen, C.B.2    Nielsen, J.E.3    Bagi, P.4    Jorgensen, A.5    Juul, A.6    Leffers, H.7
  • 92
    • 0036920846 scopus 로고    scopus 로고
    • Increased 25-hydroxyvitamin D3 1alpha-hydroxylase and reduced 25-hydroxyvitamin D3 24-hydroxylase expression in parathyroid tumors--new prospects for treatment of hyperparathyroidism with vitamin d
    • Correa, P.; Segersten, U.; Hellman, P.; Akerstrom, G.; Westin, G. Increased 25-hydroxyvitamin D3 1alpha-hydroxylase and reduced 25-hydroxyvitamin D3 24-hydroxylase expression in parathyroid tumors--new prospects for treatment of hyperparathyroidism with vitamin d. J. Clin. Endocrinol. Metab., 2002, 87 (12), 5826-5829.
    • (2002) J. Clin. Endocrinol. Metab , vol.87 , Issue.12 , pp. 5826-5829
    • Correa, P.1    Segersten, U.2    Hellman, P.3    Akerstrom, G.4    Westin, G.5
  • 94
    • 66849135038 scopus 로고    scopus 로고
    • Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells
    • Ellfolk, M.; Norlin, M.; Gyllensten, K.; Wikvall, K. Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells. Mol. Pharmacol., 2009, 75 (6), 1392-1399.
    • (2009) Mol. Pharmacol , vol.75 , Issue.6 , pp. 1392-1399
    • Ellfolk, M.1    Norlin, M.2    Gyllensten, K.3    Wikvall, K.4
  • 95
    • 33746644285 scopus 로고    scopus 로고
    • Vitamin D metabolism in human prostate cells: Implications for prostate cancer chemoprevention by vitamin D
    • Flanagan, J. N.; Young, M. V.; Persons, K. S.; Wang, L.; Mathieu, J. S.; Whitlatch, L. W.; Holick, M. F.; Chen, T. C. Vitamin D metabolism in human prostate cells: implications for prostate cancer chemoprevention by vitamin D. Anticancer Res., 2006, 26 (4A), 2567-2572.
    • (2006) Anticancer Res , vol.26 , Issue.4 A , pp. 2567-2572
    • Flanagan, J.N.1    Young, M.V.2    Persons, K.S.3    Wang, L.4    Mathieu, J.S.5    Whitlatch, L.W.6    Holick, M.F.7    Chen, T.C.8
  • 96
    • 24744447722 scopus 로고    scopus 로고
    • Cholecalciferol (vitamin D3) inhibits growth and invasion by up-regulating nuclear receptors and 25-hydroxylase (CYP27A1) in human prostate cancer cells
    • Tokar, E. J.; Webber, M. M. Cholecalciferol (vitamin D3) inhibits growth and invasion by up-regulating nuclear receptors and 25-hydroxylase (CYP27A1) in human prostate cancer cells. Clin. Exp. Metastasis, 2005, 22 (3), 275-284.
    • (2005) Clin. Exp. Metastasis , vol.22 , Issue.3 , pp. 275-284
    • Tokar, E.J.1    Webber, M.M.2
  • 97
    • 84862808037 scopus 로고    scopus 로고
    • Vitamin D 25-hydroxylase-Four decades of searching, are we there yet?
    • Zhu, J.; Deluca, H. F. Vitamin D 25-hydroxylase-Four decades of searching, are we there yet? Arch. Biochem. Biophys., 2012.
    • (2012) Arch. Biochem. Biophys
    • Zhu, J.1    Deluca, H.F.2
  • 99
    • 0036186116 scopus 로고    scopus 로고
    • Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: A novel autocrine determinant of vascular cell adhesion
    • Zehnder, D.; Bland, R.; Chana, R. S.; Wheeler, D. C.; Howie, A. J.; Williams, M. C.; Stewart, P. M.; Hewison, M. Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: a novel autocrine determinant of vascular cell adhesion. J. Am. Soc. Nephrol., 2002, 13 (3), 621-629.
    • (2002) J. Am. Soc. Nephrol , vol.13 , Issue.3 , pp. 621-629
    • Zehnder, D.1    Bland, R.2    Chana, R.S.3    Wheeler, D.C.4    Howie, A.J.5    Williams, M.C.6    Stewart, P.M.7    Hewison, M.8
  • 100
    • 0036353084 scopus 로고    scopus 로고
    • Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: Effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3)
    • Bareis, P.; Kállay, E.; Bischof, M. G.; Bises, G.; Hofer, H.; Pötzi, C.; Manhardt, T.; Bland, R.; Cross, H. S. Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3). Exp. Cell Res., 2002, 276 (2), 320-327.
    • (2002) Exp. Cell Res , vol.276 , Issue.2 , pp. 320-327
    • Bareis, P.1    Kállay, E.2    Bischof, M.G.3    Bises, G.4    Hofer, H.5    Pötzi, C.6    Manhardt, T.7    Bland, R.8    Cross, H.S.9
  • 102
    • 78650236614 scopus 로고    scopus 로고
    • Vitamin D calcidiol and calcitriol regulate vitamin D metabolizing enzymes in cervical and ovarian cancer cells
    • Kloss, M.; Fischer, D.; Thill, M.; Friedrich, M.; Cordes, T.; Salehin, D.; Diedrich, K.; Köster, F. Vitamin D, calcidiol and calcitriol regulate vitamin D metabolizing enzymes in cervical and ovarian cancer cells. Anticancer Res., 2010, 30 (11), 4429-4434.
    • (2010) Anticancer Res , vol.30 , Issue.11 , pp. 4429-4434
    • Kloss, M.1    Fischer, D.2    Thill, M.3    Friedrich, M.4    Cordes, T.5    Salehin, D.6    Diedrich, K.7    Köster, F.8
  • 103
    • 23044460496 scopus 로고    scopus 로고
    • Vitamin D(3) metabolism in human glioblastoma multiforme: Functionality of CYP27B1 splice variants, metabolism of calcidiol, and effect of calcitriol
    • Diesel, B.; Radermacher, J.; Bureik, M.; Bernhardt, R.; Seifert, M.; Reichrath, J.; Fischer, U.; Meese, E. Vitamin D(3) metabolism in human glioblastoma multiforme: functionality of CYP27B1 splice variants, metabolism of calcidiol, and effect of calcitriol. Clin. Cancer. Res., 2005, 11 (15), 5370-5380.
    • (2005) Clin. Cancer. Res , vol.11 , Issue.15 , pp. 5370-5380
    • Diesel, B.1    Radermacher, J.2    Bureik, M.3    Bernhardt, R.4    Seifert, M.5    Reichrath, J.6    Fischer, U.7    Meese, E.8
  • 104
    • 0035342721 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D(3)-1alpha-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis
    • Cross, H. S.; Bareis, P.; Hofer, H.; Bischof, M. G.; Bajna, E.; Kriwanek, S.; Bonner, E.; Peterlik, M. 25-Hydroxyvitamin D(3)-1alpha-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis. Steroids, 2001, 66 (3-5), 287-292.
    • (2001) Steroids , vol.66 , Issue.3-5 , pp. 287-292
    • Cross, H.S.1    Bareis, P.2    Hofer, H.3    Bischof, M.G.4    Bajna, E.5    Kriwanek, S.6    Bonner, E.7    Peterlik, M.8
  • 105
    • 0034806436 scopus 로고    scopus 로고
    • 25-hydroxy-vitamin d metabolism in human colon cancer cells during tumor progression
    • Bareis, P.; Bises, G.; Bischof, M. G.; Cross, H. S.; Peterlik, M. 25-hydroxy-vitamin d metabolism in human colon cancer cells during tumor progression. Biochem. Biophys. Res. Commun., 2001, 285 (4), 1012-1017.
    • (2001) Biochem. Biophys. Res. Commun , vol.285 , Issue.4 , pp. 1012-1017
    • Bareis, P.1    Bises, G.2    Bischof, M.G.3    Cross, H.S.4    Peterlik, M.5
  • 108
    • 31544473457 scopus 로고    scopus 로고
    • Upregulation of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase by butyrate in Caco-2 cells
    • Schröder, O.; Turak, S.; Daniel, C.; Gaschott, T.; Stein, J. Upregulation of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase by butyrate in Caco-2 cells. World J. Gastroenterol., 2005, 11 (45), 7136-7141.
    • (2005) World. J. Gastroenterol , vol.11 , Issue.45 , pp. 7136-7141
    • Schröder, O.1    Turak, S.2    Daniel, C.3    Gaschott, T.4    Stein, J.5
  • 109
    • 48549090882 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate
    • Chen, T. C. 25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate. Anticancer Res., 2008, 28 (4A), 2015-2017.
    • (2008) Anticancer Res , vol.28 , Issue.4 A , pp. 2015-2017
    • Chen, T.C.1
  • 110
    • 2442598406 scopus 로고    scopus 로고
    • Phytoestrogens and vitamin D metabolism: A new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas
    • Cross, H. S.; Kállay, E.; Lechner, D.; Gerdenitsch, W.; Adlercreutz, H.; Armbrecht, H. J. Phytoestrogens and vitamin D metabolism: a new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas. J. Nutr., 2004, 134 (5), 1207S-1212S.
    • (2004) J. Nutr , vol.134 , Issue.5
    • Cross, H.S.1    Kállay, E.2    Lechner, D.3    Gerdenitsch, W.4    Adlercreutz, H.5    Armbrecht, H.J.6
  • 111
    • 33746638482 scopus 로고    scopus 로고
    • Genistein and 17beta-estradiol, but not equol, regulate vitamin D synthesis in human colon and breast cancer cells
    • Lechner, D.; Bajna, E.; Adlercreutz, H.; Cross, H. S. Genistein and 17beta-estradiol, but not equol, regulate vitamin D synthesis in human colon and breast cancer cells. Anticancer Res., 2006, 26 (4A), 2597-2603.
    • (2006) Anticancer Res , vol.26 , Issue.4 A , pp. 2597-2603
    • Lechner, D.1    Bajna, E.2    Adlercreutz, H.3    Cross, H.S.4
  • 112
    • 65249141108 scopus 로고    scopus 로고
    • Constitutive NFkappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth
    • Sakamoto, K.; Maeda, S.; Hikiba, Y.; Nakagawa, H.; Hayakawa, Y.; Shibata, W.; Yanai, A.; Ogura, K.; Omata, M. Constitutive NFkappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth. Clin. Cancer Res., 2009, 15 (7), 2248-2258.
    • (2009) Clin. Cancer Res , vol.15 , Issue.7 , pp. 2248-2258
    • Sakamoto, K.1    Maeda, S.2    Hikiba, Y.3    Nakagawa, H.4    Hayakawa, Y.5    Shibata, W.6    Yanai, A.7    Ogura, K.8    Omata, M.9
  • 114
    • 5044224519 scopus 로고    scopus 로고
    • Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter
    • Ebert, R.; Jovanovic, M.; Ulmer, M.; Schneider, D.; Meissner-Weigl, J.; Adamski, J.; Jakob, F. Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter. Mol. Endocrinol., 2004, 18 (10), 2440-2450.
    • (2004) Mol. Endocrinol , vol.18 , Issue.10 , pp. 2440-2450
    • Ebert, R.1    Jovanovic, M.2    Ulmer, M.3    Schneider, D.4    Meissner-Weigl, J.5    Adamski, J.6    Jakob, F.7
  • 115
    • 0030962170 scopus 로고    scopus 로고
    • Mouse vitamin D-24-hydroxylase: Molecular cloning, tissue distribution, and transcriptional regulation by 1alpha,25-dihydroxyvitamin D3
    • Akeno, N.; Saikatsu, S.; Kawane, T.; Horiuchi, N. Mouse vitamin D-24-hydroxylase: molecular cloning, tissue distribution, and transcriptional regulation by 1alpha,25-dihydroxyvitamin D3. Endocrinology, 1997, 138 (6), 2233-2240.
    • (1997) Endocrinology , vol.138 , Issue.6 , pp. 2233-2240
    • Akeno, N.1    Saikatsu, S.2    Kawane, T.3    Horiuchi, N.4
  • 117
    • 34547942910 scopus 로고    scopus 로고
    • Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo
    • Meyer, M. B.; Zella, L. A.; Nerenz, R. D.; Pike, J. W. Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo. J. Biol. Chem., 2007, 282 (31), 22344-22352.
    • (2007) J. Biol. Chem , vol.282 , Issue.31 , pp. 22344-22352
    • Meyer, M.B.1    Zella, L.A.2    Nerenz, R.D.3    Pike, J.W.4
  • 122
    • 1342310079 scopus 로고    scopus 로고
    • Clinical significance of the overexpression of the candidate oncogene CYP24 in esophageal cancer
    • Mimori, K.; Tanaka, Y.; Yoshinaga, K.; Masuda, T.; Yamashita, K.; Okamoto, M.; Inoue, H.; Mori, M. Clinical significance of the overexpression of the candidate oncogene CYP24 in esophageal cancer. Ann. Oncol., 2004, 15 (2), 236-241.
    • (2004) Ann. Oncol , vol.15 , Issue.2 , pp. 236-241
    • Mimori, K.1    Tanaka, Y.2    Yoshinaga, K.3    Masuda, T.4    Yamashita, K.5    Okamoto, M.6    Inoue, H.7    Mori, M.8
  • 124
    • 79954576002 scopus 로고    scopus 로고
    • Expression of vitamin D receptor decreases during progression of pigmented skin lesions
    • Brozyna, A. A.; Jozwicki, W.; Janjetovic, Z.; Slominski, A. T. Expression of vitamin D receptor decreases during progression of pigmented skin lesions. Hum. Pathol., 2011, 42 (5), 618-631.
    • (2011) Hum. Pathol , vol.42 , Issue.5 , pp. 618-631
    • Brozyna, A.A.1    Jozwicki, W.2    Janjetovic, Z.3    Slominski, A.T.4
  • 125
    • 77956478256 scopus 로고    scopus 로고
    • Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: A study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions
    • Lopes, N.; Sousa, B.; Martins, D.; Gomes, M.; Vieira, D.; Veronese, L. A.; Milanezi, F.; Paredes, J.; Costa, J. L.; Schmitt, F. Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions. BMC Cancer, 2010, 10, 483.
    • (2010) BMC Cancer , vol.10 , pp. 483
    • Lopes, N.1    Sousa, B.2    Martins, D.3    Gomes, M.4    Vieira, D.5    Veronese, L.A.6    Milanezi, F.7    Paredes, J.8    Costa, J.L.9    Schmitt, F.10
  • 126
    • 77954758969 scopus 로고    scopus 로고
    • Expression of vitamin D receptor (VDR), cyclooxygenase-2 (COX-2) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in benign and malignant ovarian tissue and 25-hydroxycholecalciferol (25(OH2)D3) and prostaglandin E2 (PGE2) serum level in ovarian cancer patients
    • Thill, M.; Fischer, D.; Kelling, K.; Hoellen, F.; Dittmer, C.; Hornemann, A.; Salehin, D.; Diedrich, K.; Friedrich, M.; Becker, S. Expression of vitamin D receptor (VDR), cyclooxygenase-2 (COX-2) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in benign and malignant ovarian tissue and 25-hydroxycholecalciferol (25(OH2)D3) and prostaglandin E2 (PGE2) serum level in ovarian cancer patients. J. Steroid. Biochem. Mol. Biol., 2010, 121 (1-2), 387-390.
    • (2010) J. Steroid. Biochem. Mol. Biol , vol.121 , Issue.1-2 , pp. 387-390
    • Thill, M.1    Fischer, D.2    Kelling, K.3    Hoellen, F.4    Dittmer, C.5    Hornemann, A.6    Salehin, D.7    Diedrich, K.8    Friedrich, M.9    Becker, S.10
  • 128
    • 0029096145 scopus 로고
    • Vitamin D receptor expression, 24-hydroxylase activity, and inhibition of growth by 1alpha,25-dihydroxyvitamin D3 in seven human prostatic carcinoma cell lines
    • Miller, G. J.; Stapleton, G. E.; Hedlund, T. E.; Moffat, K. A. Vitamin D receptor expression, 24-hydroxylase activity, and inhibition of growth by 1alpha,25-dihydroxyvitamin D3 in seven human prostatic carcinoma cell lines. Clin. Cancer Res., 1995, 1 (9), 997-1003.
    • (1995) Clin. Cancer Res , vol.1 , Issue.9 , pp. 997-1003
    • Miller, G.J.1    Stapleton, G.E.2    Hedlund, T.E.3    Moffat, K.A.4
  • 130
    • 0034807280 scopus 로고    scopus 로고
    • Methylation and colorectal cancer
    • Jubb, A. M.; Bell, S. M.; Quirke, P. Methylation and colorectal cancer. J. Pathol., 2001, 195 (1), 111-134.
    • (2001) J. Pathol , vol.195 , Issue.1 , pp. 111-134
    • Jubb, A.M.1    Bell, S.M.2    Quirke, P.3
  • 131
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg, A. P.; Vogelstein, B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature, 1983, 301 (5895), 89-92.
    • (1983) Nature , vol.301 , Issue.5895 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 132
    • 0021950948 scopus 로고
    • Hypomethylation of DNA from benign and malignant human colon neoplasms
    • Goelz, S. E.; Vogelstein, B.; Hamilton, S. R.; Feinberg, A. P. Hypomethylation of DNA from benign and malignant human colon neoplasms. Science, 1985, 228 (4696), 187-190.
    • (1985) Science , vol.228 , Issue.4696 , pp. 187-190
    • Goelz, S.E.1    Vogelstein, B.2    Hamilton, S.R.3    Feinberg, A.P.4
  • 133
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman, J. G.; Baylin, S. B. Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med., 2003, 349 (21), 2042-2054.
    • (2003) N. Engl. J. Med , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 134
    • 0036605995 scopus 로고    scopus 로고
    • Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells
    • Shi, H.; Yan, P. S.; Chen, C. M.; Rahmatpanah, F.; Lofton-Day, C.; Caldwell, C. W.; Huang, T. H. Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells. Cancer. Res., 2002, 62 (11), 3214-3220.
    • (2002) Cancer. Res , vol.62 , Issue.11 , pp. 3214-3220
    • Shi, H.1    Yan, P.S.2    Chen, C.M.3    Rahmatpanah, F.4    Lofton-Day, C.5    Caldwell, C.W.6    Huang, T.H.7
  • 136
    • 18044385966 scopus 로고    scopus 로고
    • Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells
    • Khorchide, M.; Lechner, D.; Cross, H. S. Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells. J. Steroid Biochem. Mol. Biol., 2005, 93 (2-5), 167-172.
    • (2005) J. Steroid Biochem. Mol. Biol , vol.93 , Issue.2-5 , pp. 167-172
    • Khorchide, M.1    Lechner, D.2    Cross, H.S.3
  • 137
    • 0041317202 scopus 로고    scopus 로고
    • Extensive methylation of CpG island of CYP24 gene in osteoblastic ROS17/2.8 cells
    • Ohyama, Y.; Kusada, T.; Yamasaki, T.; Ide, H. Extensive methylation of CpG island of CYP24 gene in osteoblastic ROS17/2.8 cells. Nucleic Acids Res. Suppl., 2002, (2), 249-250.
    • (2002) Nucleic Acids Res , Issue.2 SUPPL. , pp. 249-250
    • Ohyama, Y.1    Kusada, T.2    Yamasaki, T.3    Ide, H.4
  • 138
    • 34247895767 scopus 로고    scopus 로고
    • Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol
    • Chung, I.; Karpf, A. R.; Muindi, J. R.; Conroy, J. M.; Nowak, N. J.; Johnson, C. S.; Trump, D. L. Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol. J. Biol. Chem., 2007, 282 (12), 8704-8714.
    • (2007) J. Biol. Chem , vol.282 , Issue.12 , pp. 8704-8714
    • Chung, I.1    Karpf, A.R.2    Muindi, J.R.3    Conroy, J.M.4    Nowak, N.J.5    Johnson, C.S.6    Trump, D.L.7
  • 139
    • 77955037065 scopus 로고    scopus 로고
    • Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer
    • Luo, W.; Karpf, A. R.; Deeb, K. K.; Muindi, J. R.; Morrison, C. D.; Johnson, C. S.; Trump, D. L. Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. Cancer Res., 2010, 70 (14), 5953-5962.
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 5953-5962
    • Luo, W.1    Karpf, A.R.2    Deeb, K.K.3    Muindi, J.R.4    Morrison, C.D.5    Johnson, C.S.6    Trump, D.L.7
  • 140
    • 79961220956 scopus 로고    scopus 로고
    • Differential vitamin D 24-hydroxylase/CYP24A1 gene promoter methylation in endothelium from benign and malignant human prostate
    • Deeb, K. K.; Luo, W.; Karpf, A. R.; Omilian, A. R.; Bshara, W.; Tian, L.; Tangrea, M. A.; Morrison, C. D.; Johnson, C. S.; Trump, D. L. Differential vitamin D 24-hydroxylase/CYP24A1 gene promoter methylation in endothelium from benign and malignant human prostate. Epigenetics, 2011, 6 (8), 994-1000.
    • (2011) Epigenetics , vol.6 , Issue.8 , pp. 994-1000
    • Deeb, K.K.1    Luo, W.2    Karpf, A.R.3    Omilian, A.R.4    Bshara, W.5    Tian, L.6    Tangrea, M.A.7    Morrison, C.D.8    Johnson, C.S.9    Trump, D.L.10
  • 141
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D.; Weinberg, R. A. Hallmarks of cancer: the next generation. Cell, 2011, 144 (5), 646-674.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 142
    • 0027978368 scopus 로고
    • Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2
    • Reifenberger, G.; Reifenberger, J.; Ichimura, K.; Meltzer, P. S.; Collins, V. P. Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2. Cancer Res., 1994, 54 (16), 4299-4303.
    • (1994) Cancer Res , vol.54 , Issue.16 , pp. 4299-4303
    • Reifenberger, G.1    Reifenberger, J.2    Ichimura, K.3    Meltzer, P.S.4    Collins, V.P.5
  • 143
    • 0034896365 scopus 로고    scopus 로고
    • Amplification and expression of splice variants of the gene encoding the P450 cytochrome 25-hydroxyvitamin D(3) 1,alpha-hydroxylase (CYP 27B1) in human malignant glioma
    • Maas, R. M.; Reus, K.; Diesel, B.; Steudel, W. I.; Feiden, W.; Fischer, U.; Meese, E. Amplification and expression of splice variants of the gene encoding the P450 cytochrome 25-hydroxyvitamin D(3) 1,alpha-hydroxylase (CYP 27B1) in human malignant glioma. Clin. Cancer Res., 2001, 7 (4), 868-875.
    • (2001) Clin. Cancer Res , vol.7 , Issue.4 , pp. 868-875
    • Maas, R.M.1    Reus, K.2    Diesel, B.3    Steudel, W.I.4    Feiden, W.5    Fischer, U.6    Meese, E.7
  • 145
    • 0141889935 scopus 로고    scopus 로고
    • High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use of CGH analysis of cDNA microarrays
    • Squire, J. A.; Pei, J.; Marrano, P.; Beheshti, B.; Bayani, J.; Lim, G.; Moldovan, L.; Zielenska, M. High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use of CGH analysis of cDNA microarrays. Genes Chromosomes Cancer, 2003, 38 (3), 215-225.
    • (2003) Genes Chromosomes Cancer , vol.38 , Issue.3 , pp. 215-225
    • Squire, J.A.1    Pei, J.2    Marrano, P.3    Beheshti, B.4    Bayani, J.5    Lim, G.6    Moldovan, L.7    Zielenska, M.8
  • 148
    • 79951886089 scopus 로고    scopus 로고
    • Prostate cancer susceptibility Loci identified on chromosome 12 in African Americans
    • Bonilla, C.; Hooker, S.; Mason, T.; Bock, C. H.; Kittles, R. A. Prostate cancer susceptibility Loci identified on chromosome 12 in African Americans. PLoS One, 2011, 6 (2), e16044.
    • (2011) PLoS One , vol.6 , Issue.2
    • Bonilla, C.1    Hooker, S.2    Mason, T.3    Bock, C.H.4    Kittles, R.A.5
  • 149
    • 35448993870 scopus 로고    scopus 로고
    • Comprehensive association analysis of the vitamin D pathway genes, VDR, CYP27B1, and CYP24A1, in prostate cancer
    • Holick, C. N.; Stanford, J. L.; Kwon, E. M.; Ostrander, E. A.; Nejentsev, S.; Peters, U. Comprehensive association analysis of the vitamin D pathway genes, VDR, CYP27B1, and CYP24A1, in prostate cancer. Cancer Epidemiol. Biomarkers Prev., 2007, 16 (10), 1990-1999.
    • (2007) Cancer Epidemiol. Biomarkers Prev , vol.16 , Issue.10 , pp. 1990-1999
    • Holick, C.N.1    Stanford, J.L.2    Kwon, E.M.3    Ostrander, E.A.4    Nejentsev, S.5    Peters, U.6
  • 153
    • 58149085877 scopus 로고    scopus 로고
    • Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism
    • Lauter, K.; Arnold, A. Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism. J. Bone Miner. Res., 2009, 24 (1), 102-104.
    • (2009) J. Bone Miner. Res , vol.24 , Issue.1 , pp. 102-104
    • Lauter, K.1    Arnold, A.2
  • 159
    • 84863563725 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D
    • Jones, G.; Prosser, D. E.; Kaufmann, M. 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D. Arch. Biochem. Biophys., 2011.
    • (2011) Arch. Biochem. Biophys
    • Jones, G.1    Prosser, D.E.2    Kaufmann, M.3
  • 160
    • 55349087215 scopus 로고    scopus 로고
    • A novel SNP in a vitamin D response element of the CYP24A1 promoter reduces protein binding, transactivation, and gene expression
    • Roff, A.; Wilson, R. T. A novel SNP in a vitamin D response element of the CYP24A1 promoter reduces protein binding, transactivation, and gene expression. J. Steroid Biochem. Mol. Biol., 2008, 112 (1-3), 47-54.
    • (2008) J. Steroid Biochem. Mol. Biol , vol.112 , Issue.1-3 , pp. 47-54
    • Roff, A.1    Wilson, R.T.2
  • 161
    • 68549118801 scopus 로고    scopus 로고
    • The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: A review of the literature
    • Kostner, K.; Denzer, N.; Muller, C. S.; Klein, R.; Tilgen, W.; Reichrath, J. The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature. Anticancer research, 2009, 29 (9), 3511-3536.
    • (2009) Anticancer Research , vol.29 , Issue.9 , pp. 3511-3536
    • Kostner, K.1    Denzer, N.2    Muller, C.S.3    Klein, R.4    Tilgen, W.5    Reichrath, J.6
  • 162
    • 80054026938 scopus 로고    scopus 로고
    • Vitamin D receptor (VDR) polymorphisms and skin cancer: A systematic review
    • Denzer, N.; Vogt, T.; Reichrath, J. Vitamin D receptor (VDR) polymorphisms and skin cancer: A systematic review. Dermatoendocrinol., 2011, 3 (3), 205-210.
    • (2011) Dermatoendocrinol , vol.3 , Issue.3 , pp. 205-210
    • Denzer, N.1    Vogt, T.2    Reichrath, J.3
  • 164
    • 81155124251 scopus 로고    scopus 로고
    • MicroRNAs in the pathogenesis of cancer
    • Lovat, F.; Valeri, N.; Croce, C. M. MicroRNAs in the pathogenesis of cancer. Semin. Oncol., 2011, 38 (6), 724-733.
    • (2011) Semin. Oncol , vol.38 , Issue.6 , pp. 724-733
    • Lovat, F.1    Valeri, N.2    Croce, C.M.3
  • 166
    • 3042594279 scopus 로고    scopus 로고
    • Towards a complete picture of splice variants of the gene for 25-hydroxyvitamin D31alpha-hydroxylase in brain and skin cancer
    • Diesel, B.; Seifert, M.; Radermacher, J.; Fischer, U.; Tilgen, W.; Reichrath, J.; Meese, E. Towards a complete picture of splice variants of the gene for 25-hydroxyvitamin D31alpha-hydroxylase in brain and skin cancer. J. Steroid Biochem. Mol. Biol., 2004, 89-90 (1-5), 527-532.
    • (2004) J. Steroid Biochem. Mol. Biol , vol.89-90 , Issue.1-5 , pp. 527-532
    • Diesel, B.1    Seifert, M.2    Radermacher, J.3    Fischer, U.4    Tilgen, W.5    Reichrath, J.6    Meese, E.7
  • 167
    • 34347214450 scopus 로고    scopus 로고
    • Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production
    • Wu, S.; Ren, S.; Nguyen, L.; Adams, J. S.; Hewison, M. Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production. Endocrinology, 2007, 148 (7), 3410-3418.
    • (2007) Endocrinology , vol.148 , Issue.7 , pp. 3410-3418
    • Wu, S.1    Ren, S.2    Nguyen, L.3    Adams, J.S.4    Hewison, M.5
  • 169
    • 33947150498 scopus 로고    scopus 로고
    • Expression of 25 hydroxyvitamin D3-1alpha-hydroxylase in human endometrial tissue
    • Becker, S.; Cordes, T.; Diesing, D.; Diedrich, K.; Friedrich, M. Expression of 25 hydroxyvitamin D3-1alpha-hydroxylase in human endometrial tissue. J. Steroid Biochem. Mol. Biol., 2007, 103 (3-5), 771-775.
    • (2007) J. Steroid Biochem. Mol. Biol , vol.103 , Issue.3-5 , pp. 771-775
    • Becker, S.1    Cordes, T.2    Diesing, D.3    Diedrich, K.4    Friedrich, M.5
  • 170
    • 68549122662 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D3 1alphahydroxylase splice variants in benign and malignant ovarian cell lines and tissue
    • Fischer, D.; Thomé, M.; Becker, S.; Cordes, T.; Diedrich, K.; Friedrich, M.; Thill, M. 25-Hydroxyvitamin D3 1alphahydroxylase splice variants in benign and malignant ovarian cell lines and tissue. Anticancer Res., 2009, 29 (9), 3627-3633.
    • (2009) Anticancer Res , vol.29 , Issue.9 , pp. 3627-3633
    • Fischer, D.1    Thomé, M.2    Becker, S.3    Cordes, T.4    Diedrich, K.5    Friedrich, M.6    Thill, M.7
  • 171
    • 70349333224 scopus 로고    scopus 로고
    • Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b
    • Komagata, S.; Nakajima, M.; Takagi, S.; Mohri, T.; Taniya, T.; Yokoi, T. Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b. Mol. Pharmacol., 2009, 76 (4), 702-709.
    • (2009) Mol. Pharmacol , vol.76 , Issue.4 , pp. 702-709
    • Komagata, S.1    Nakajima, M.2    Takagi, S.3    Mohri, T.4    Taniya, T.5    Yokoi, T.6
  • 173
    • 77954910711 scopus 로고    scopus 로고
    • The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells
    • Matilainen, J. M.; Malinen, M.; Turunen, M. M.; Carlberg, C.; Väisänen, S. The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells. J. Biol. Chem., 2010, 285 (31), 24174-24183.
    • (2010) J. Biol. Chem , vol.285 , Issue.31 , pp. 24174-24183
    • Matilainen, J.M.1    Malinen, M.2    Turunen, M.M.3    Carlberg, C.4    Väisänen, S.5
  • 174
    • 20144362158 scopus 로고    scopus 로고
    • Alternative splicing of vitamin D-24-hydroxylase: A novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis
    • Ren, S.; Nguyen, L.; Wu, S.; Encinas, C.; Adams, J. S.; Hewison, M. Alternative splicing of vitamin D-24-hydroxylase: a novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis. J. Biol. Chem., 2005, 280 (21), 20604-20611.
    • (2005) J. Biol. Chem , vol.280 , Issue.21 , pp. 20604-20611
    • Ren, S.1    Nguyen, L.2    Wu, S.3    Encinas, C.4    Adams, J.S.5    Hewison, M.6
  • 176
    • 33947124593 scopus 로고    scopus 로고
    • CYP24 splicing variants are associated with different patterns of constitutive and calcitriol-inducible CYP24 activity in human prostate cancer cell lines
    • Muindi, J. R.; Nganga, A.; Engler, K. L.; Coignet, L. J.; Johnson, C. S.; Trump, D. L. CYP24 splicing variants are associated with different patterns of constitutive and calcitriol-inducible CYP24 activity in human prostate cancer cell lines. J. Steroid Biochem. Mol. Biol., 2007, 103 (3-5), 334-337.
    • (2007) J. Steroid Biochem. Mol. Biol , vol.103 , Issue.3-5 , pp. 334-337
    • Muindi, J.R.1    Nganga, A.2    Engler, K.L.3    Coignet, L.J.4    Johnson, C.S.5    Trump, D.L.6
  • 180
    • 55949120225 scopus 로고    scopus 로고
    • Role of bile acid secretion in human colorectal cancer
    • Peterlik, M. Role of bile acid secretion in human colorectal cancer. Wien. Med. Wochenschr., 2008, 158 (19-20), 539-541.
    • (2008) Wien. Med. Wochenschr , vol.158 , Issue.19-20 , pp. 539-541
    • Peterlik, M.1
  • 181
    • 34547145317 scopus 로고    scopus 로고
    • Lithocholic acid can carry out in vivo functions of vitamin D
    • Nehring, J. A.; Zierold, C.; DeLuca, H. F. Lithocholic acid can carry out in vivo functions of vitamin D. Proc. Natl. Acad. Sci. U S A, 2007, 104 (24), 10006-10009.
    • (2007) Proc. Natl. Acad. Sci. U S A , vol.104 , Issue.24 , pp. 10006-10009
    • Nehring, J.A.1    Zierold, C.2    Deluca, H.F.3
  • 182
    • 12544253005 scopus 로고    scopus 로고
    • Calcium sensing receptor in human colon carcinoma: Interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3)
    • Chakrabarty, S.; Wang, H.; Canaff, L.; Hendy, G. N.; Appelman, H.; Varani, J. Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3). Cancer Res., 2005, 65 (2), 493-498.
    • (2005) Cancer Res , vol.65 , Issue.2 , pp. 493-498
    • Chakrabarty, S.1    Wang, H.2    Canaff, L.3    Hendy, G.N.4    Appelman, H.5    Varani, J.6
  • 183
    • 0037119447 scopus 로고    scopus 로고
    • Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D
    • Canaff, L.; Hendy, G. N. Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D. J. Biol. Chem., 2002, 277 (33), 30337-30350.
    • (2002) J. Biol. Chem , vol.277 , Issue.33 , pp. 30337-30350
    • Canaff, L.1    Hendy, G.N.2
  • 184
    • 84855502399 scopus 로고    scopus 로고
    • Negative cross-talk between calcium-sensing receptor and beta-catenin signaling systems in colonic epithelium
    • Rey, O.; Chang, W.; Bikle, D.; Rozengurt, N.; Young, S. H.; Rozengurt, E. Negative cross-talk between calcium-sensing receptor and beta-catenin signaling systems in colonic epithelium. J. Biol. Chem., 2012, 287 (2), 1158-1167.
    • (2012) Biol. Chem , vol.287 , Issue.2 , pp. 1158-1167
    • Rey, O.1    Chang, W.2    Bikle, D.3    Rozengurt, N.4    Young, S.H.5    Rozengurt, E.6
  • 185
    • 65249144951 scopus 로고    scopus 로고
    • The role of the calciumsensing receptor in the development and progression of cancer
    • Saidak, Z.; Mentaverri, R.; Brown, E. M. The role of the calciumsensing receptor in the development and progression of cancer. Endocr. Rev., 2009, 30 (2), 178-195.
    • (2009) Endocr. Rev , vol.30 , Issue.2 , pp. 178-195
    • Saidak, Z.1    Mentaverri, R.2    Brown, E.M.3
  • 186
    • 0842305872 scopus 로고    scopus 로고
    • Molecular and functional characterization of the extracellular calcium-sensing receptor in human colon cancer cells
    • Kallay, E.; Bonner, E.; Wrba, F.; Thakker, R. V.; Peterlik, M.; Cross, H. S. Molecular and functional characterization of the extracellular calcium-sensing receptor in human colon cancer cells. Oncol. Res., 2003, 13 (12), 551-559.
    • (2003) Oncol. Res , vol.13 , Issue.12 , pp. 551-559
    • Kallay, E.1    Bonner, E.2    Wrba, F.3    Thakker, R.V.4    Peterlik, M.5    Cross, H.S.6
  • 187
    • 0037224244 scopus 로고    scopus 로고
    • Extracellular calcium and calcium sensing receptor function in human colon carcinomas: Promotion of E-cadherin expression and suppression of beta-catenin/TCF activation
    • Chakrabarty, S.; Radjendirane, V.; Appelman, H.; Varani, J. Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of beta-catenin/TCF activation. Cancer Res., 2003, 63 (1), 67-71.
    • (2003) Cancer Res , vol.63 , Issue.1 , pp. 67-71
    • Chakrabarty, S.1    Radjendirane, V.2    Appelman, H.3    Varani, J.4
  • 188
    • 65949102999 scopus 로고    scopus 로고
    • The calcium-sensing receptor--a driver of colon cell differentiation
    • Whitfield, J. F. The calcium-sensing receptor--a driver of colon cell differentiation. Curr. Pharm. Biotechnol., 2009, 10 (3), 311-316.
    • (2009) Curr. Pharm. Biotechnol , vol.10 , Issue.3 , pp. 311-316
    • Whitfield, J.F.1
  • 189
    • 0342314479 scopus 로고    scopus 로고
    • Immunocytochemical localization of the extracellular calcium-sensing receptor in normal and malignant human large intestinal mucosa
    • Sheinin, Y.; Kallay, E.; Wrba, F.; Kriwanek, S.; Peterlik, M.; Cross, H. S. Immunocytochemical localization of the extracellular calcium-sensing receptor in normal and malignant human large intestinal mucosa. J. Histochem. Cytochem., 2000, 48 (5), 595-602.
    • (2000) J. Histochem. Cytochem , vol.48 , Issue.5 , pp. 595-602
    • Sheinin, Y.1    Kallay, E.2    Wrba, F.3    Kriwanek, S.4    Peterlik, M.5    Cross, H.S.6
  • 190
    • 0033934254 scopus 로고    scopus 로고
    • Dietary calcium and growth modulation of human colon cancer cells: Role of the extracellular calcium-sensing receptor
    • Kallay, E.; Bajna, E.; Wrba, F.; Kriwanek, S.; Peterlik, M.; Cross, H. S. Dietary calcium and growth modulation of human colon cancer cells: role of the extracellular calcium-sensing receptor. Cancer Detect. Prev., 2000, 24 (2), 127-136.
    • (2000) Cancer Detect. Prev , vol.24 , Issue.2 , pp. 127-136
    • Kallay, E.1    Bajna, E.2    Wrba, F.3    Kriwanek, S.4    Peterlik, M.5    Cross, H.S.6
  • 192
    • 68749112871 scopus 로고    scopus 로고
    • Calcium-sensing receptor in cancer: Good cop or bad cop?
    • Chakravarti, B.; Dwivedi, S. K.; Mithal, A.; Chattopadhyay, N. Calcium-sensing receptor in cancer: good cop or bad cop? Endocrine, 2009, 35 (3), 271-284.
    • (2009) Endocrine , vol.35 , Issue.3 , pp. 271-284
    • Chakravarti, B.1    Dwivedi, S.K.2    Mithal, A.3    Chattopadhyay, N.4
  • 193
    • 54049137686 scopus 로고    scopus 로고
    • Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells
    • Mamillapalli, R.; VanHouten, J.; Zawalich, W.; Wysolmerski, J. Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells. J. Biol. Chem., 2008, 283 (36), 24435-24447.
    • (2008) J. Biol. Chem , vol.283 , Issue.36 , pp. 24435-24447
    • Mamillapalli, R.1    Vanhouten, J.2    Zawalich, W.3    Wysolmerski, J.4
  • 195
    • 34547103285 scopus 로고    scopus 로고
    • Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells
    • MacLeod, R. J.; Hayes, M.; Pacheco, I. Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells. Am. J. Physiol. Gastrointest. Liver Physiol., 2007, 293 (1), G403-411.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol , vol.293 , Issue.1
    • Macleod, R.J.1    Hayes, M.2    Pacheco, I.3
  • 196
    • 0034098691 scopus 로고    scopus 로고
    • Biology of the adenomatous polyposis coli tumor suppressor
    • Goss, K. H.; Groden, J. Biology of the adenomatous polyposis coli tumor suppressor. J. Clin. Oncol., 2000, 18 (9), 1967-1979.
    • (2000) J. Clin. Oncol , vol.18 , Issue.9 , pp. 1967-1979
    • Goss, K.H.1    Groden, J.2
  • 197
    • 84858159230 scopus 로고    scopus 로고
    • Mechanism of action of vitamin D and the vitamin D receptor in colorectal cancer prevention and treatment
    • Byers, S. W.; Rowlands, T.; Beildeck, M.; Bong, Y. S. Mechanism of action of vitamin D and the vitamin D receptor in colorectal cancer prevention and treatment. Rev. Endocr. Metab. Disord., 2012, 13 (1), 31-38.
    • (2012) Rev. Endocr. Metab. Disord , vol.13 , Issue.1 , pp. 31-38
    • Byers, S.W.1    Rowlands, T.2    Beildeck, M.3    Bong, Y.S.4
  • 198
    • 55749104413 scopus 로고    scopus 로고
    • Vitamin D and Wnt/beta-catenin pathway in colon cancer: Role and regulation of DICKKOPF genes
    • Pendas-Franco, N.; Aguilera, O.; Pereira, F.; Gonzalez-Sancho, J. M.; Munoz, A. Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. Anticancer Res., 2008, 28 (5A), 2613-2623.
    • (2008) Anticancer Res , vol.28 , Issue.5 A , pp. 2613-2623
    • Pendas-Franco, N.1    Aguilera, O.2    Pereira, F.3    Gonzalez-Sancho, J.M.4    Munoz, A.5
  • 200
    • 62349138124 scopus 로고    scopus 로고
    • The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
    • Greenhough, A.; Smartt, H. J.; Moore, A. E.; Roberts, H. R.; Williams, A. C.; Paraskeva, C.; Kaidi, A. The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis, 2009, 30 (3), 377-386.
    • (2009) Carcinogenesis , vol.30 , Issue.3 , pp. 377-386
    • Greenhough, A.1    Smartt, H.J.2    Moore, A.E.3    Roberts, H.R.4    Williams, A.C.5    Paraskeva, C.6    Kaidi, A.7
  • 201
    • 77649179672 scopus 로고    scopus 로고
    • Eicosanoids and cancer
    • Wang, D.; Dubois, R. N. Eicosanoids and cancer. Nat. Rev. Cancer, 10 (3), 181-193.
    • Nat. Rev. Cancer , vol.10 , Issue.3 , pp. 181-193
    • Wang, D.1    Dubois, R.N.2
  • 202
    • 4143107932 scopus 로고    scopus 로고
    • Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition
    • Simmons, D. L.; Botting, R. M.; Hla, T. Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. Pharmacol. Rev., 2004, 56 (3), 387-437.
    • (2004) Pharmacol. Rev , vol.56 , Issue.3 , pp. 387-437
    • Simmons, D.L.1    Botting, R.M.2    Hla, T.3
  • 203
    • 33846031547 scopus 로고    scopus 로고
    • Gender-specific modulation of markers for premalignancy by nutritional soy and calcium in the mouse colon
    • Bises, G.; Bajna, E.; Manhardt, T.; Gerdenitsch, W.; Kallay, E.; Cross, H. S. Gender-specific modulation of markers for premalignancy by nutritional soy and calcium in the mouse colon. J. Nutr., 2007, 137 (1 Suppl), 211S-215S.
    • (2007) J. Nutr , vol.137 , Issue.1 SUPPL.
    • Bises, G.1    Bajna, E.2    Manhardt, T.3    Gerdenitsch, W.4    Kallay, E.5    Cross, H.S.6
  • 204
    • 0031555878 scopus 로고    scopus 로고
    • Calcium-dependent c-myc protooncogene expression and proliferation of Caco-2 cells: A role for a luminal extracellular calcium-sensing receptor
    • Kallay, E.; Kifor, O.; Chattopadhyay, N.; Brown, E. M.; Bischof, M. G.; Peterlik, M.; Cross, H. S. Calcium-dependent c-myc protooncogene expression and proliferation of Caco-2 cells: a role for a luminal extracellular calcium-sensing receptor. Biochem. Biophys. Res. Commun., 1997, 232 (1), 80-83.
    • (1997) Biochem. Biophys. Res. Commun , vol.232 , Issue.1 , pp. 80-83
    • Kallay, E.1    Kifor, O.2    Chattopadhyay, N.3    Brown, E.M.4    Bischof, M.G.5    Peterlik, M.6    Cross, H.S.7
  • 205
    • 53449098889 scopus 로고    scopus 로고
    • Nutritional calcium modulates colonic expression of vitamin D receptor and pregnane X receptor target genes
    • Nittke, T.; Selig, S.; Kallay, E.; Cross, H. S. Nutritional calcium modulates colonic expression of vitamin D receptor and pregnane X receptor target genes. Mol. Nutr. Food. Res., 2008, 52 Suppl 1, S45-51.
    • (2008) Mol. Nutr. Food. Res , vol.52 , Issue.SUPPL. 1
    • Nittke, T.1    Selig, S.2    Kallay, E.3    Cross, H.S.4
  • 206
    • 24744452645 scopus 로고    scopus 로고
    • Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells
    • Moreno, J.; Krishnan, A. V.; Swami, S.; Nonn, L.; Peehl, D. M.; Feldman, D. Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells. Cancer Res., 2005, 65 (17), 7917-7925.
    • (2005) Cancer Res , vol.65 , Issue.17 , pp. 7917-7925
    • Moreno, J.1    Krishnan, A.V.2    Swami, S.3    Nonn, L.4    Peehl, D.M.5    Feldman, D.6
  • 207
    • 33947176624 scopus 로고    scopus 로고
    • Novel pathways that contribute to the anti-proliferative and chemopreventive activities of calcitriol in prostate cancer
    • Krishnan, A. V.; Moreno, J.; Nonn, L.; Malloy, P.; Swami, S.; Peng, L.; Peehl, D. M.; Feldman, D. Novel pathways that contribute to the anti-proliferative and chemopreventive activities of calcitriol in prostate cancer. J. Steroid Biochem. Mol. Biol., 2007, 103 (3-5), 694-702.
    • (2007) J. Steroid Biochem. Mol. Biol , vol.103 , Issue.3-5 , pp. 694-702
    • Krishnan, A.V.1    Moreno, J.2    Nonn, L.3    Malloy, P.4    Swami, S.5    Peng, L.6    Peehl, D.M.7    Feldman, D.8
  • 209
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna, G.; Adorini, L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J. Immunol., 2000, 164 (5), 2405-2411.
    • (2000) J. Immunol , vol.164 , Issue.5 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 210
    • 77950119759 scopus 로고    scopus 로고
    • Vitamin D supplementation and regulatory T cells in apparently healthy subjects: Vitamin D treatment for autoimmune diseases
    • Prietl, B.; Pilz, S.; Wolf, M.; Tomaschitz, A.; Obermayer-Pietsch, B.; Graninger, W.; Pieber, T. R. Vitamin D supplementation and regulatory T cells in apparently healthy subjects: vitamin D treatment for autoimmune diseases? Isr. Med. Assoc. J., 2010, 12 (3), 136-139.
    • (2010) Isr. Med. Assoc. J , vol.12 , Issue.3 , pp. 136-139
    • Prietl, B.1    Pilz, S.2    Wolf, M.3    Tomaschitz, A.4    Obermayer-Pietsch, B.5    Graninger, W.6    Pieber, T.R.7
  • 211
    • 79960122931 scopus 로고    scopus 로고
    • Dual roles of immune cells and their factors in cancer development and progression
    • Zamarron, B. F.; Chen, W. Dual roles of immune cells and their factors in cancer development and progression. Int. J. Biol. Sci., 2011, 7 (5), 651-658.
    • (2011) Int. J. Biol. Sci , vol.7 , Issue.5 , pp. 651-658
    • Zamarron, B.F.1    Chen, W.2
  • 212
    • 0023894660 scopus 로고
    • 25-Hydroxylation of vitamin D3 by a cytochrome P-450 from rabbit liver mitochondria
    • Dahlback, H.; Wikvall, K. 25-Hydroxylation of vitamin D3 by a cytochrome P-450 from rabbit liver mitochondria. Biochem. J., 1988, 252 (1), 207-213.
    • (1988) Biochem. J , vol.252 , Issue.1 , pp. 207-213
    • Dahlback, H.1    Wikvall, K.2
  • 216
    • 21344450763 scopus 로고    scopus 로고
    • Cytochrome P450 3A and 2B6 in the developing kidney: Implications for ifosfamide nephrotoxicity
    • Aleksa, K.; Matsell, D.; Krausz, K.; Gelboin, H.; Ito, S.; Koren, G. Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity. Pediatr. Nephrol., 2005, 20 (7), 872-885.
    • (2005) Pediatr. Nephrol , vol.20 , Issue.7 , pp. 872-885
    • Aleksa, K.1    Matsell, D.2    Krausz, K.3    Gelboin, H.4    Ito, S.5    Koren, G.6
  • 217
    • 27744539745 scopus 로고    scopus 로고
    • Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa
    • Bergheim, I.; Bode, C.; Parlesak, A. Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa. BMC Clin. Pharmacol., 2005, 5, 4.
    • (2005) BMC Clin. Pharmacol , vol.5 , pp. 4
    • Bergheim, I.1    Bode, C.2    Parlesak, A.3
  • 219
    • 1842430562 scopus 로고    scopus 로고
    • Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues
    • Enayetallah, A. E.; French, R. A.; Thibodeau, M. S.; Grant, D. F. Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues. J. Histochem. Cytochem., 2004, 52 (4), 447-454.
    • (2004) J. Histochem. Cytochem , vol.52 , Issue.4 , pp. 447-454
    • Enayetallah, A.E.1    French, R.A.2    Thibodeau, M.S.3    Grant, D.F.4
  • 220
    • 0030923112 scopus 로고    scopus 로고
    • Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes
    • Wu, S.; Chen, W.; Murphy, E.; Gabel, S.; Tomer, K. B.; Foley, J.; Steenbergen, C.; Falck, J. R.; Moomaw, C. R.; Zeldin, D. C. Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes. J. Biol. Chem., 1997, 272 (19), 12551-12559.
    • (1997) J. Biol. Chem , vol.272 , Issue.19 , pp. 12551-12559
    • Wu, S.1    Chen, W.2    Murphy, E.3    Gabel, S.4    Tomer, K.B.5    Foley, J.6    Steenbergen, C.7    Falck, J.R.8    Moomaw, C.R.9    Zeldin, D.C.10
  • 221
    • 33644861778 scopus 로고    scopus 로고
    • Localization of rat cytochrome P450 in various tissues and comparison of arachidonic acid metabolism by rat P450 with that by human P450 orthologs
    • Imaoka, S.; Hashizume, T.; Funae, Y. Localization of rat cytochrome P450 in various tissues and comparison of arachidonic acid metabolism by rat P450 with that by human P450 orthologs. Drug. Metab. Pharmacokinet., 2005, 20 (6), 478-484.
    • (2005) Drug. Metab. Pharmacokinet , vol.20 , Issue.6 , pp. 478-484
    • Imaoka, S.1    Hashizume, T.2    Funae, Y.3
  • 222
    • 0028791854 scopus 로고
    • Purification from pig kidney of a microsomal cytochrome P450 catalyzing 1 alpha-hydroxylation of 25-hydroxyvitamin D3
    • Axen, E. Purification from pig kidney of a microsomal cytochrome P450 catalyzing 1 alpha-hydroxylation of 25-hydroxyvitamin D3. FEBS Lett., 1995, 375 (3), 277-279.
    • (1995) FEBS Lett , vol.375 , Issue.3 , pp. 277-279
    • Axen, E.1
  • 223
    • 0037172427 scopus 로고    scopus 로고
    • Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase mRNA in individuals with colorectal cancer
    • Ogunkolade, B. W.; Boucher, B. J.; Fairclough, P. D.; Hitman, G. A.; Dorudi, S.; Jenkins, P. J.; Bustin, S. A. Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase mRNA in individuals with colorectal cancer. Lancet, 2002, 359 (9320), 1831-1832.
    • (2002) Lancet , vol.359 , Issue.9320 , pp. 1831-1832
    • Ogunkolade, B.W.1    Boucher, B.J.2    Fairclough, P.D.3    Hitman, G.A.4    Dorudi, S.5    Jenkins, P.J.6    Bustin, S.A.7
  • 224
    • 61449090703 scopus 로고    scopus 로고
    • Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase, and vitamin D receptor mRNA in normal and malignant breast tissue
    • McCarthy, K.; Laban, C.; Bustin, S. A.; Ogunkolade, W.; Khalaf, S.; Carpenter, R.; Jenkins, P. J. Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase, and vitamin D receptor mRNA in normal and malignant breast tissue. Anticancer Res., 2009, 29 (1), 155-157.
    • (2009) Anticancer Res , vol.29 , Issue.1 , pp. 155-157
    • McCarthy, K.1    Laban, C.2    Bustin, S.A.3    Ogunkolade, W.4    Khalaf, S.5    Carpenter, R.6    Jenkins, P.J.7
  • 226
    • 33746822914 scopus 로고    scopus 로고
    • 25(OH)D3 and 1,25(OH)2D3 serum concentration and breast tissue expression of 1alpha-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer
    • de Lyra, E. C.; da Silva, I. A.; Katayama, M. L.; Brentani, M. M.; Nonogaki, S.; Góes, J. C.; Folgueira, M. A. 25(OH)D3 and 1,25(OH)2D3 serum concentration and breast tissue expression of 1alpha-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer. J. Steroid Biochem. Mol. Biol., 2006, 100 (4-5), 184-192.
    • (2006) J. Steroid Biochem. Mol. Biol , vol.100 , Issue.4-5 , pp. 184-192
    • de Lyra, E.C.1    da Silva, I.A.2    Katayama, M.L.3    Brentani, M.M.4    Nonogaki, S.5    Góes, J.C.6    Folgueira, M.A.7
  • 227
    • 3042517352 scopus 로고    scopus 로고
    • Mechanisms of decreased Vitamin D 1alphahydroxylase activity in prostate cancer cells
    • Ma, J. F.; Nonn, L.; Campbell, M. J.; Hewison, M.; Feldman, D.; Peehl, D. M. Mechanisms of decreased Vitamin D 1alphahydroxylase activity in prostate cancer cells. Mol. Cell. Endocrinol., 2004, 221 (1-2), 67-74.
    • (2004) Mol. Cell. Endocrinol , vol.221 , Issue.1-2 , pp. 67-74
    • Ma, J.F.1    Nonn, L.2    Campbell, M.J.3    Hewison, M.4    Feldman, D.5    Peehl, D.M.6
  • 228
    • 0037302258 scopus 로고    scopus 로고
    • Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer
    • Chen, T. C.; Wang, L.; Whitlatch, L. W.; Flanagan, J. N.; Holick, M. F. Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer. J. Cell. Biochem., 2003, 88 (2), 315-322.
    • (2003) J. Cell. Biochem , vol.88 , Issue.2 , pp. 315-322
    • Chen, T.C.1    Wang, L.2    Whitlatch, L.W.3    Flanagan, J.N.4    Holick, M.F.5
  • 229
    • 0035297540 scopus 로고    scopus 로고
    • Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition
    • Hsu, J. Y.; Feldman, D.; McNeal, J. E.; Peehl, D. M. Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition. Cancer Res., 2001, 61 (7), 2852-2856.
    • (2001) Cancer Res , vol.61 , Issue.7 , pp. 2852-2856
    • Hsu, J.Y.1    Feldman, D.2    McNeal, J.E.3    Peehl, D.M.4
  • 232
    • 33344474685 scopus 로고    scopus 로고
    • 25-hydroxyvitamin D3 1alpha-hydroxylase and vitamin D receptor expression in papillary thyroid carcinoma
    • Khadzkou, K.; Buchwald, P.; Westin, G.; Dralle, H.; Akerström, G.; Hellman, P. 25-hydroxyvitamin D3 1alpha-hydroxylase and vitamin D receptor expression in papillary thyroid carcinoma. J. Histochem. Cytochem., 2006, 54 (3), 355-361.
    • (2006) J. Histochem. Cytochem , vol.54 , Issue.3 , pp. 355-361
    • Khadzkou, K.1    Buchwald, P.2    Westin, G.3    Dralle, H.4    Akerström, G.5    Hellman, P.6
  • 233
    • 4344592313 scopus 로고    scopus 로고
    • Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: A novel form of humoral hypercalcemia of malignancy
    • Evans, K. N.; Taylor, H.; Zehnder, D.; Kilby, M. D.; Bulmer, J. N.; Shah, F.; Adams, J. S.; Hewison, M. Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy. Am. J. Pathol., 2004, 165 (3), 807-813.
    • (2004) Am. J. Pathol , vol.165 , Issue.3 , pp. 807-813
    • Evans, K.N.1    Taylor, H.2    Zehnder, D.3    Kilby, M.D.4    Bulmer, J.N.5    Shah, F.6    Adams, J.S.7    Hewison, M.8
  • 235
    • 77951127705 scopus 로고    scopus 로고
    • Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
    • Blomberg Jensen, M.; Andersen, C. B.; Nielsen, J. E.; Bagi, P.; Jørgensen, A.; Juul, A.; Leffers, H. Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer. J. Steroid Biochem. Mol. Biol., 2010, 121 (1-2), 376-382.
    • (2010) J. Steroid Biochem. Mol. Biol , vol.121 , Issue.1-2 , pp. 376-382
    • Blomberg, J.M.1    Andersen, C.B.2    Nielsen, J.E.3    Bagi, P.4    Jørgensen, A.5    Juul, A.6    Leffers, H.7


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