Non-stationary 13C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation

BMC Systems Biology

Volumn 8, Issue 1, 2014, Pages

  Nicolae, Averina ^a   Wahrheit, Judith ^a   Bahnemann, Janina ^b   Zeng, An Ping ^b   Heinzle, Elmar ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Chinese hamster ovary cells; CHO; Compartmentation; Mammalian cell culture; Mammalian metabolism; Metabolic flux analysis; Metabolic transport; Mitochondria; Reversibility

Indexed keywords

CARBON;

ANIMAL; ARTICLE; BATCH CELL CULTURE; CHO CELL LINE; CRICETULUS; EXTRACELLULAR SPACE; HAMSTER; METABOLIC FLUX ANALYSIS; METABOLISM; METABOLOMICS; METHODOLOGY; STAINING; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BATCH CELL CULTURE TECHNIQUES; BIOLOGICAL TRANSPORT; CARBON ISOTOPES; CHO CELLS; CRICETINAE; CRICETULUS; EXTRACELLULAR SPACE; METABOLIC FLUX ANALYSIS; METABOLOMICS; STAINING AND LABELING;

EID: 84899952895     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-8-50     Document Type: Article

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