Metabolic control at the cytosol-mitochondria interface in different growth phases of CHO cells

Metabolic Engineering

Volumn 23, Issue , 2014, Pages 9-21

  Wahrheit, Judith ^a   Niklas, Jens ^a,b   Heinzle, Elmar ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b INSILICO Biotechnology GmbH   (Germany)

Author keywords

CHO; Compartmentation; Enzyme activities; Mammalian cell culture; Metabolic flux analysis; Metabolic switches; Mitochondria

Indexed keywords

CHINESE HAMSTER OVARY CELLS; CHO; COMPARTMENTATION; GLYCOLYTIC REGULATIONS; MAMMALIAN CELL CULTURE; METABOLIC FLUX ANALYSIS; SITU ENZYME ACTIVITIES; SPATIAL AND TEMPORAL RESOLUTIONS;

CELL CULTURE; ENZYME ACTIVITY; MITOCHONDRIA; PATHOLOGY;

METABOLISM;

AMINOTRANSFERASE; GLYCOLYTIC ENZYME; OXALOACETIC ACID; PYRUVIC ACID;

ANIMAL CELL; ARTICLE; BATCH CELL CULTURE; CELL GROWTH; CELL METABOLISM; CELL TRANSPORT; CELLULAR DISTRIBUTION; CHO CELL; CITRIC ACID CYCLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; FEMALE; GLYCOLYSIS; GROWTH CURVE; IN VIVO STUDY; METABOLIC PARAMETERS; METABOLIC REGULATION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CHO CELL LINE; CRICETULUS; ENZYMOLOGY; HAMSTER; PHYSIOLOGY;

ANIMALS; CHO CELLS; CITRIC ACID CYCLE; CRICETINAE; CRICETULUS; CYTOSOL; GLYCOLYSIS; MITOCHONDRIA;

EID: 84896821388     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.02.001     Document Type: Article

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