The benefits of being transient: Isotope-based metabolic flux analysis at the short time scale

Applied Microbiology and Biotechnology

Volumn 91, Issue 5, 2011, Pages 1247-1265

  Nöh, Katharina ^a   Wiechert, Wolfgang ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

Labeling time constants; Metabolic engineering; Metabolic networks; Non stationary 13C metabolic flux analysis; Systems biology; Transient isotope labeling experiments

Indexed keywords

METABOLIC ENGINEERING; METABOLIC NETWORK; NONSTATIONARY; SYSTEMS BIOLOGY; TIME CONSTANTS;

C (PROGRAMMING LANGUAGE); CULTIVATION; EXPERIMENTS; GENES; ISOTOPES; LAKES; MATHEMATICAL MODELS;

METABOLISM;

CARBON 13; ISOTOPE;

CARBON ISOTOPE; CELL ORGANELLE; CULTIVATION; DATA SET; EXPERIMENTAL STUDY; FLUX MEASUREMENT; GENE EXPRESSION; ISOTOPIC ANALYSIS; MATHEMATICAL ANALYSIS; MEASUREMENT METHOD; METABOLISM; METABOLITE; NUMERICAL MODEL; PROTEIN; QUANTITATIVE ANALYSIS; RESEARCH WORK; STEADY-STATE EQUILIBRIUM; TIMESCALE;

CELL INTERACTION; CELL METABOLISM; CELL TRANSPORT; DILUTION; IN VIVO STUDY; LABELING INDEX; MATHEMATICAL MODEL; MEDICAL RESEARCH; METABOLIC ENGINEERING; METABOLIC FLUX ANALYSIS; METABOLISM; METABOLOME; REVIEW;

ANIMALS; BACTERIA; CARBON ISOTOPES; CELLS; FUNGI; HUMANS; ISOTOPE LABELING; TIME FACTORS;

EID: 80052611173     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3390-4     Document Type: Review

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