Metabolic flux analysis of CHO cell metabolism in the late non-growth phase

Biotechnology and Bioengineering

Volumn 108, Issue 1, 2011, Pages 82-92

  Sengupta, Neelanjan ^a   Rose, Steven T ^b   Morgan, John A ^a  

^a PURDUE UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

13C flux analysis; Mammalian cell culture; Oxidative stress

Indexed keywords

CELL BIOLOGY; CHINESE HAMSTER OVARY CELLS; CHO CELL; COMMONLY USED; CULTURE CONDITIONS; FLUX ANALYSIS; FLUX NETWORK; GROWTH PHASE; HUMAN THERAPEUTICS; MAMMALIAN CELL CULTURE; METABOLIC FLUX; METABOLIC FLUX ANALYSIS; PENTOSE PHOSPHATE PATHWAY; PROCESS IMPROVEMENT; PYRUVATES; SIGNIFICANT IMPACTS; TCA CYCLE;

ANIMAL CELL CULTURE; CARBON DIOXIDE; DISSOLVED OXYGEN; GLOBAL WARMING; GLUCOSE; INTERNET PROTOCOLS; MAMMALS; METABOLISM; NUTRIENTS; PATHOLOGY;

CELL CULTURE;

CARBON DIOXIDE; DISSOLVED OXYGEN; LACTIC ACID; PENTOSE PHOSPHATE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ARTICLE; BACTERIUM CULTURE; CELL CULTURE; CELL GROWTH; CELL METABOLISM; CHO CELL; ENZYME SYNTHESIS; GLUCOSE INTAKE; GLYCOLYSIS; NONHUMAN; PENTOSE PHOSPHATE CYCLE; STEADY STATE; STOICHIOMETRY; TEMPERATURE;

ANIMALS; CHO CELLS; CITRIC ACID CYCLE; CRICETINAE; CRICETULUS; EPITHELIAL CELLS; GLUCOSE; GLUCOSE-6-PHOSPHATE; GLYCOLYSIS; NADP; PENTOSE PHOSPHATE PATHWAY;

CRICETULUS GRISEUS; MAMMALIA;

EID: 78649410664     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22890     Document Type: Article

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