Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells

Metabolic Engineering

Volumn 15, Issue 1, 2013, Pages 206-217

  Murphy, Taylor A ^a   Dang, Chi V ^b   Young, Jamey D ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cancer metabolism; Isotopomer analysis; Lymphoma; Mass spectrometry; Metabolic flux analysis; Warburg effect

Indexed keywords

B CELLS; DIRECT EXTRACTION; EXPRESSION LEVELS; FLUX ANALYSIS; GLUCOSE UPTAKE; INTRACELLULAR METABOLITES; ISOTOPIC ANALYSIS; ISOTOPIC MEASUREMENT; ISOTOPOMER ANALYSIS; LYMPHOMA; MAXIMUM FLUX; METABOLIC FLUX; METABOLIC FLUX ANALYSIS; MITOCHONDRIAL PATHWAYS; NONSTATIONARY; ONCOPROTEINS; OXIDATIVE METABOLISM; TCA CYCLE; TUMOR MODELS; WARBURG EFFECTS;

AMINO ACIDS; CELLS; CYTOLOGY; GLUCOSE; ISOTOPES; MASS SPECTROMETRY; PHYSIOLOGY; RNA;

METABOLISM;

AMINO ACID; CARBON 13; GLUCOSE; MYC PROTEIN; CARBON;

AEROBIC METABOLISM; ANALYSIS; ARTICLE; B LYMPHOCYTE; HUMAN; HUMAN CELL; MEASUREMENT; METABOLIC FLUX ANALYSIS; METABOLIC PARAMETERS; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; CELL LINE; GENETICS; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY;

B-LYMPHOCYTES; CARBON ISOTOPES; CELL LINE; GLUCOSE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROTO-ONCOGENE PROTEINS C-MYC;

MLCS; MLOWN;

EID: 84872376676     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2012.07.008     Document Type: Article

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