Elucidating a key component of cancer metastasis: CXCL12 (SDF-1α) binding to CXCR4

Journal of Chemical Information and Modeling

Volumn 54, Issue 4, 2014, Pages 1174-1188

  Tamamis, Phanourios ^a   Floudas, Christodoulos A ^a  

^a Princeton University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELL SIGNALING; COMPUTATIONAL CHEMISTRY; DISEASES; FREE ENERGY; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PATHOLOGY;

CHEMOKINE RECEPTOR CXCR4; COMPUTATIONAL PROTOCOLS; CONFORMATIONAL SEARCH; FREE-ENERGY CALCULATIONS; HETEROGENEOUS DIELECTRICS; INTERMOLECULAR INTERACTIONS; MOLECULAR DYNAMICS SIMULATIONS; TRANS-MEMBRANE DOMAINS;

BINDING ENERGY;

CHEMOKINE RECEPTOR CXCR4; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; PROTEIN BINDING; STROMAL CELL DERIVED FACTOR 1;

CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; METASTASIS;

CHEMOKINE CXCL12; HUMANS; MODELS, MOLECULAR; NEOPLASM METASTASIS; PROTEIN BINDING; RECEPTORS, CXCR4;

EID: 84899708038     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci500069y     Document Type: Article

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